{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T03:08:54Z","timestamp":1774062534756,"version":"3.50.1"},"reference-count":26,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2021,12,5]],"date-time":"2021-12-05T00:00:00Z","timestamp":1638662400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["1.1.1.2\/VIAA\/1\/16\/242"],"award-info":[{"award-number":["1.1.1.2\/VIAA\/1\/16\/242"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>N,N-Dimethylaziridine-2-carboxamides react with organolithium reagents yielding 2-aziridinylketones. The reaction with one equivalent of organolithium compound is selective to amide carbonyl at a low (\u221278 \u00b0C) temperature. These ketones, in reaction with organolithium reagents, give symmetrical and unsymmetrical aziridinyl carbinols. The usage of excess phenyllithium may serve as a special N-Boc-protecting group cleavage method for acid-sensitive substrates.<\/jats:p>","DOI":"10.3390\/ijms222313145","type":"journal-article","created":{"date-parts":[[2021,12,5]],"date-time":"2021-12-05T21:01:45Z","timestamp":1638738105000},"page":"13145","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["An Easy Route to Aziridine Ketones and Carbinols"],"prefix":"10.3390","volume":"22","author":[{"given":"Boriss","family":"Strumfs","sequence":"first","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"},{"name":"Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jekaterina","family":"Hermane","sequence":"additional","affiliation":[{"name":"Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey","family":"Belyakov","sequence":"additional","affiliation":[{"name":"Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artjoms","family":"Sobolevs","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirils","family":"Velikijs","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romans","family":"Uljanovs","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peteris","family":"Trapencieris","sequence":"additional","affiliation":[{"name":"Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7393-9524","authenticated-orcid":false,"given":"Ilze","family":"Strumfa","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/bs.aihch.2018.12.003","article-title":"Advances in synthesis and chemistry of aziridines","volume":"129","author":"Singh","year":"2019","journal-title":"Adv. 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