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The fusion of monocytes\/macrophages with tumor cells may promote cancer metastasis. We describe types and examples of monocyte\u2013macrophage lineage cell fusion and the role of actin-based structures in cell fusion.<\/jats:p>","DOI":"10.3390\/ijms23126553","type":"journal-article","created":{"date-parts":[[2022,6,12]],"date-time":"2022-06-12T09:26:48Z","timestamp":1655026008000},"page":"6553","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Monocyte\u2013Macrophage Lineage Cell Fusion"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5192-8584","authenticated-orcid":false,"given":"Malgorzata","family":"Kloc","sequence":"first","affiliation":[{"name":"Transplant Immununology, The Houston Methodist Research Institute, Houston, TX 77030, USA"},{"name":"Department of Surgery, The Houston Methodist Hospital, Houston, TX 77030, USA"},{"name":"Department of Genetics, MD Anderson Cancer Center, The University of Texas, Houston, TX 78712, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arijita","family":"Subuddhi","sequence":"additional","affiliation":[{"name":"Transplant Immununology, The Houston Methodist Research Institute, Houston, TX 77030, USA"},{"name":"Department of Surgery, The Houston Methodist Hospital, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Uosef","sequence":"additional","affiliation":[{"name":"Transplant Immununology, The Houston Methodist Research Institute, Houston, TX 77030, USA"},{"name":"Department of Surgery, The Houston Methodist Hospital, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2772-5127","authenticated-orcid":false,"given":"Jacek Z.","family":"Kubiak","sequence":"additional","affiliation":[{"name":"Dynamics and Mechanics of Epithelia Group, Faculty of Medicine, Institute of Genetics and Development of Rennes, University of Rennes, CNRS, UMR 6290, 35000 Rennes, France"},{"name":"Laboratory of Molecular Oncology and Innovative Therapies, Department of Oncology, Military Institute of Medicine, 04-141 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafik M.","family":"Ghobrial","sequence":"additional","affiliation":[{"name":"Transplant Immununology, The Houston Methodist Research Institute, Houston, TX 77030, USA"},{"name":"Department of Surgery, The Houston Methodist Hospital, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Burr, D.B., and Allen, M.R. 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