{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:30:35Z","timestamp":1792801835348,"version":"4.5.0"},"reference-count":11,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T00:00:00Z","timestamp":1666656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Psoriasis is a chronic inflammatory skin disease with many comorbidities resulting from not only local but also systemic inflammation [...]<\/jats:p>","DOI":"10.3390\/ijms232112851","type":"journal-article","created":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T22:00:27Z","timestamp":1666735227000},"page":"12851","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["New Insights into Psoriasis"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6286-0693","authenticated-orcid":false,"given":"Boguslaw","family":"Nedoszytko","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology, Medical University of Gda\u0144sk, 80-211 Gda\u0144sk, Poland"},{"name":"Molecular Laboratory, Invicta Fertility and Reproductive Center, 81-740 Sopot, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8372-0438","authenticated-orcid":false,"given":"Agnieszka","family":"Owczarczyk-Saczonek","sequence":"additional","affiliation":[{"name":"Dermatology, Sexually Transmitted Diseases and Clinical Immunology, School of Medicine, University Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3176-9870","authenticated-orcid":false,"given":"Dorota","family":"Krasowska","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, 20-081 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneta","family":"Szczerkowska-Dobosz","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology, Medical University of Gda\u0144sk, 80-211 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.5114\/ada.2020.94832","article-title":"Pathogenesis of psoriasis in the \u201comic\u201d era. Part I. Epidemiology, clinical manifestation, immunological and neuroendocrine disturbances","volume":"37","author":"Samotij","year":"2020","journal-title":"Adv. Dermatol. Allergol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"283","DOI":"10.5114\/ada.2020.96243","article-title":"Pathogenesis of psoriasis in the \u201comic\u201d era. Part II. Genetic, genomic and epigenetic changes in psoriasis","volume":"37","author":"Nedoszytko","year":"2020","journal-title":"Adv. Dermatol. Allergol."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Bro\u017cyna, A.A., Slominski, R.M., Nedoszytko, B., Zmijewski, M.A., and Slominski, A.T. (2022). Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23158575"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Wierzbicka, J.M., Piotrowska, A., Purzycka-Bohdan, D., Olszewska, A., Nowak, J.I., Szczerkowska-Dobosz, A., Nedoszytko, B., Nowicki, R.J., and \u017bmijewski, M.A. (2021). The Effects of Vitamin D on the Expression of IL-33 and Its Receptor ST2 in Skin Cells; Potential Implication for Psoriasis. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms222312907"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Marek-Jozefowicz, L., Czajkowski, R., Borkowska, A., Nedoszytko, B., \u017bmijewski, M.A., Cuba\u0142a, W.J., and Slominski, A.T. (2022). The Brain\u2013Skin Axis in Psoriasis\u2014Psychological, Psychiatric, Hormonal, and Dermatological Aspects. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23020669"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Alalaiwe, A., Chen, C.-Y., Chang, Z.-Y., Sung, J.-T., Chuang, S.-Y., and Fang, J.-Y. (2021). Psoriasiform Inflammation Is Associated with Mitochondrial Fission\/GDAP1L1 Signaling in Macrophages. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms221910410"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Czerwi\u0144ska, J., and Owczarczyk-Saczonek, A. (2022). The Role of the Neutrophilic Network in the Pathogenesis of Psoriasis. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23031840"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Nowowiejska, J., Baran, A., and Flisiak, I. (2021). Aberrations in Lipid Expression and Metabolism in Psoriasis. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22126561"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Ikeda, K., Morizane, S., Akagi, T., Hiramatsu-Asano, S., Tachibana, K., Yahagi, A., Iseki, M., Kaneto, H., Wada, J., and Ishihara, K. (2022). Obesity and Dyslipidemia Synergistically Exacerbate Psoriatic Skin Inflammation. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23084312"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Purzycka-Bohdan, D., Kisielnicka, A., Bohdan, M., Szczerkowska-Dobosz, A., Sobalska-Kwapis, M., Nedoszytko, B., and Nowicki, R.J. (2021). Analysis of the Potential Genetic Links between Psoriasis and Cardiovascular Risk Factors. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22169063"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Merzel \u0160abovi\u0107, E.K., Starbek Zorko, M., and Jani\u0107, M. (2022). Killing Two Birds with One Stone: Potential Therapies Targeting Psoriasis and Atherosclerosis at the Same Time. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23126648"}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/23\/21\/12851\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:02:10Z","timestamp":1760144530000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/23\/21\/12851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,25]]},"references-count":11,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2022,11]]}},"alternative-id":["ijms232112851"],"URL":"https:\/\/doi.org\/10.3390\/ijms232112851","relation":{},"ISSN":["1422-0067"],"issn-type":[{"value":"1422-0067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,25]]}}}