{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T09:02:46Z","timestamp":1791450166791,"version":"4.3.3"},"reference-count":51,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2022,12,10]],"date-time":"2022-12-10T00:00:00Z","timestamp":1670630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015829","name":"Polish Ministry of Health","doi-asserted-by":"publisher","award":["6\/6\/4\/1\/NPZ\/2017\/1210\/13522"],"award-info":[{"award-number":["6\/6\/4\/1\/NPZ\/2017\/1210\/13522"]}],"id":[{"id":"10.13039\/501100015829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015829","name":"Polish Ministry of Health","doi-asserted-by":"publisher","award":["1W51\/M\/MB2\/N\/20"],"award-info":[{"award-number":["1W51\/M\/MB2\/N\/20"]}],"id":[{"id":"10.13039\/501100015829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015829","name":"Polish Ministry of Health","doi-asserted-by":"publisher","award":["101008193 TRENDO"],"award-info":[{"award-number":["101008193 TRENDO"]}],"id":[{"id":"10.13039\/501100015829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004166","name":"Medical University of Warsaw, Poland","doi-asserted-by":"publisher","award":["6\/6\/4\/1\/NPZ\/2017\/1210\/13522"],"award-info":[{"award-number":["6\/6\/4\/1\/NPZ\/2017\/1210\/13522"]}],"id":[{"id":"10.13039\/501100004166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004166","name":"Medical University of Warsaw, Poland","doi-asserted-by":"publisher","award":["1W51\/M\/MB2\/N\/20"],"award-info":[{"award-number":["1W51\/M\/MB2\/N\/20"]}],"id":[{"id":"10.13039\/501100004166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004166","name":"Medical University of Warsaw, Poland","doi-asserted-by":"publisher","award":["101008193 TRENDO"],"award-info":[{"award-number":["101008193 TRENDO"]}],"id":[{"id":"10.13039\/501100004166","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Union\u2019s Horizon 2020 Research and Innovation Program under the Marie Sk\u0142odowska-Curie","award":["6\/6\/4\/1\/NPZ\/2017\/1210\/13522"],"award-info":[{"award-number":["6\/6\/4\/1\/NPZ\/2017\/1210\/13522"]}]},{"name":"European Union\u2019s Horizon 2020 Research and Innovation Program under the Marie Sk\u0142odowska-Curie","award":["1W51\/M\/MB2\/N\/20"],"award-info":[{"award-number":["1W51\/M\/MB2\/N\/20"]}]},{"name":"European Union\u2019s Horizon 2020 Research and Innovation Program under the Marie Sk\u0142odowska-Curie","award":["101008193 TRENDO"],"award-info":[{"award-number":["101008193 TRENDO"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Laparoscopy as a diagnostic tool for patients with suspected endometriosis is associated with several potentially life-threatening complications. Therefore, it is imperative to identify reliable, non-invasive biomarkers of the disease. The aim of this study was to analyse the concentrations of fibronectin and type IV collagen in peritoneal fluid and plasma to assess their role as potential biomarkers in the diagnosis of endometriosis. Fibronectin and collagen IV protein levels were assessed by surface plasmon resonance imaging (SPRi) biosensors with the usage of monoclonal antibodies. All patients enrolled in the study were referred for laparoscopy for the diagnosis of infertility or chronic pelvic pain (n = 84). The study group included patients with endometriosis confirmed during surgery (n = 49). The concentration of fibronectin in the plasma (329.3 \u00b1 98.5 mg\/L) and peritoneal fluid (26.8 \u00b1 11.1 \u03bcg\/L) in women with endometriosis was significantly higher than in the control group (251.2 \u00b1 84.0 mg\/L, 7.0 \u00b1 5.9 \u03bcg\/L). Fibronectin levels were independent of endometriosis stage (p = 0.874, p = 0.469). No significant differences were observed in collagen IV levels (p = 0.385, p = 0.465). The presence of elevated levels of fibronectin may indicate abnormalities in cell\u2013ECM signalling during the course of endometriosis, and may be a potential biomarker for early detection.<\/jats:p>","DOI":"10.3390\/ijms232415669","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T01:42:27Z","timestamp":1670809347000},"page":"15669","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Plasma and Peritoneal Fluid Fibronectin and Collagen IV Levels as Potential Biomarkers of Endometriosis"],"prefix":"10.3390","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2822-4896","authenticated-orcid":false,"given":"Damian","family":"Warzecha","sequence":"first","affiliation":[{"name":"1st Department of Obstetrics and Gynaecology, Medical University of Warsaw, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Za\u0142\u0119cka","sequence":"additional","affiliation":[{"name":"1st Department of Obstetrics and Gynaecology, Medical University of Warsaw, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Ma\u0144ka","sequence":"additional","affiliation":[{"name":"Angelius Provita Hospital, 40-611 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz","family":"Kiecka","sequence":"additional","affiliation":[{"name":"Angelius Provita Hospital, 40-611 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Lipa","sequence":"additional","affiliation":[{"name":"1st Department of Obstetrics and Gynaecology, Medical University of Warsaw, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4306-6590","authenticated-orcid":false,"given":"Robert","family":"Spaczy\u0144ski","sequence":"additional","affiliation":[{"name":"Division of Infertility and Reproductive Endocrinology, Department of Gynaecology, Obstetrics and Gynaecological Oncology, Poznan University of Medical Sciences, 61-701 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Piekarski","sequence":"additional","affiliation":[{"name":"Division of Infertility and Reproductive Endocrinology, Department of Gynaecology, Obstetrics and Gynaecological Oncology, Poznan University of Medical Sciences, 61-701 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"Banaszewska","sequence":"additional","affiliation":[{"name":"Division of Infertility and Reproductive Endocrinology, Department of Gynaecology, Obstetrics and Gynaecological Oncology, Poznan University of Medical Sciences, 61-701 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7373-7690","authenticated-orcid":false,"given":"Artur","family":"Jakimiuk","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Institute of Mother and Child in Warsaw, 01-211 Warsaw, Poland"},{"name":"Department of Obstetrics and Gynaecology, Central Clinical Hospital of the Ministry of Interior, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3647-3550","authenticated-orcid":false,"given":"Tadeusz","family":"Issat","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Institute of Mother and Child in Warsaw, 01-211 Warsaw, Poland"},{"name":"Department of Obstetrics and Gynaecology, Central Clinical Hospital of the Ministry of Interior, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Rokita","sequence":"additional","affiliation":[{"name":"Collegium Medicum, Jan Kochanowski University in Kielce, 25-369 Kielce, Poland"},{"name":"Clinic of Obstetrics and Gynaecology, Provincial Combined Hospital in Kielce, 25-736 Kielce, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5740-9822","authenticated-orcid":false,"given":"Jakub","family":"M\u0142odawski","sequence":"additional","affiliation":[{"name":"Collegium Medicum, Jan Kochanowski University in Kielce, 25-369 Kielce, Poland"},{"name":"Clinic of Obstetrics and Gynaecology, Provincial Combined Hospital in Kielce, 25-736 Kielce, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Szubert","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics, Medical University of Lodz, 90-419 Lodz, Poland"},{"name":"Department of Surgical Gynaecology and Oncology, Medical University of Lodz, 90-419 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Sieroszewski","sequence":"additional","affiliation":[{"name":"Department of Gynaecology and Obstetrics, Medical University of Lodz, 90-419 Lodz, Poland"},{"name":"Department of Fetal Medicine and Gynaecology, Medical University of Lodz, 90-419 Lodz, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9196-8548","authenticated-orcid":false,"given":"Grzegorz","family":"Raba","sequence":"additional","affiliation":[{"name":"Clinic of Obstetrics and Gynaecology in Przemysl, 37-700 Przemysl, Poland"},{"name":"Department of Gynaecology and Obstetrics, University of Rzeszow, 35-310 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Szczupak","sequence":"additional","affiliation":[{"name":"Clinic of Obstetrics and Gynaecology in Przemysl, 37-700 Przemysl, Poland"},{"name":"Department of Gynaecology and Obstetrics, University of Rzeszow, 35-310 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Kluz","sequence":"additional","affiliation":[{"name":"Department of Gynaecology, Gynaecology Oncology and Obstetrics, Institute of Medical Sciences, Medical College of Rzeszow University, 35-310 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Kluza","sequence":"additional","affiliation":[{"name":"Department of Gynaecology, Gynaecology Oncology and Obstetrics, Institute of Medical Sciences, Medical College of Rzeszow University, 35-310 Rzeszow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2581-3668","authenticated-orcid":false,"given":"Miros\u0142aw","family":"Wielgo\u015b","sequence":"additional","affiliation":[{"name":"1st Department of Obstetrics and Gynaecology, Medical University of Warsaw, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1829-7466","authenticated-orcid":false,"given":"\u0141ukasz","family":"O\u0142dak","sequence":"additional","affiliation":[{"name":"Bioanalysis Laboratory, Faculty of Chemistry, University of Bialystok, 15-245 Bialystok, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Le\u015bniewska","sequence":"additional","affiliation":[{"name":"Bioanalysis Laboratory, Faculty of Chemistry, University of Bialystok, 15-245 Bialystok, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Gorodkiewicz","sequence":"additional","affiliation":[{"name":"Bioanalysis Laboratory, Faculty of Chemistry, University of Bialystok, 15-245 Bialystok, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Lauda\u0144ski","sequence":"additional","affiliation":[{"name":"1st Department of Obstetrics and Gynaecology, Medical University of Warsaw, 02-091 Warsaw, Poland"},{"name":"OVIklinika Infertility Center, 01-377 Warsaw, Poland"},{"name":"Women\u2019s Health Research Institute, Calisia University, 62-800 Kalisz, Poland"},{"name":"Department of Obstetrics, Gynaecology, Gynecology and Gynaecological Oncology, Medical University of Warsaw, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,10]]},"reference":[{"key":"ref_1","first-page":"349","article-title":"Endometriosis still a challenge","volume":"7","author":"Mehedintu","year":"2014","journal-title":"J. Med. Life"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Smolarz, B., Szyllo, K., and Romanowicz, H. (2021). Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature). Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms221910554"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1055\/a-1033-9588","article-title":"Cycle-related Diarrhea and Dysmenorrhea are Independent Predictors of Peritoneal Endometriosis, Cycle-related Dyschezia is an Independent Predictor of Rectal Involvement","volume":"80","author":"Nicolaus","year":"2020","journal-title":"Geburtshilfe Frauenheilkd."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/aogs.13082","article-title":"Endometriosis-associated infertility: Aspects of pathophysiological mechanisms and treatment options","volume":"96","author":"Tanbo","year":"2017","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"ref_5","first-page":"273","article-title":"Ethiopathogenic mechanisms of endometriosis-related infertility","volume":"23","author":"Broi","year":"2019","journal-title":"JBRA Assist. Reprod."},{"key":"ref_6","first-page":"68","article-title":"Quality of life in women with endometriosis: A narrative overview","volume":"111","author":"Barra","year":"2020","journal-title":"Minerva Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1080\/01443615.2019.1603217","article-title":"Diagnostic delay for superficial and deep endometriosis in the United Kingdom","volume":"40","author":"Ghai","year":"2020","journal-title":"J. Obstet. Gynaecol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.advms.2022.02.003","article-title":"Diagnostic delay of endometriosis in adults and adolescence-current stage of knowledge","volume":"67","author":"Wrobel","year":"2022","journal-title":"Adv. Med. Sci."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Golawski, K., Soczewica, R., Kacperczyk-Bartnik, J., Manka, G., Kiecka, M., Lipa, M., Warzecha, D., Spaczynski, R., Piekarski, P., and Banaszewska, B. (2022). The Role of Cadherin 12 (CDH12) in the Peritoneal Fluid among Patients with Endometriosis and Endometriosis-Related Infertility. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph191811586"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Bartnik, P., Kacperczyk-Bartnik, J., Go\u0142awski, K., Sierdzi\u0144ski, J., Ma\u0144ka, G., Kiecka, M., Lipa, M., Warzecha, D., Spaczy\u0144ski, R., and Piekarski, P. (2022). Plasma and Peritoneal Fluid ZEB Levels in Patients with Endometriosis and Infertility. Biomedicines, 10.","DOI":"10.3390\/biomedicines10102460"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Kacperczyk-Bartnik, J., Bartnik, P., Go\u0142awski, K., Sierdzi\u0144ski, J., Ma\u0144ka, G., Kiecka, M., Lipa, M., Warzecha, D., Spaczy\u0144ski, R., and Piekarski, P. (2022). Plasma and Peritoneal Poly (ADP-Ribose) Polymerase Levels in Patients with Endometriosis. Biomedicines, 10.","DOI":"10.3390\/biomedicines10102451"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Lagana, A.S., Garzon, S., Gotte, M., Vigano, P., Franchi, M., Ghezzi, F., and Martin, D.C. (2019). The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20225615"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.fertnstert.2018.10.013","article-title":"Pathogenesis of endometriosis: The genetic\/epigenetic theory","volume":"111","author":"Koninckx","year":"2019","journal-title":"Fertil. Steril."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1016\/j.cell.2021.04.041","article-title":"Endometriosis: Etiology, pathobiology, and therapeutic prospects","volume":"184","author":"Saunders","year":"2021","journal-title":"Cell"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/gye.16.2.137.141","article-title":"Chemokine growth-regulated-alpha: A possible role in the pathogenesis of endometriosis","volume":"16","author":"Szamatowicz","year":"2002","journal-title":"Gynecol. Endocrinol."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Zalecka, J., Pankiewicz, K., Issat, T., and Laudanski, P. (2022). Molecular Mechanisms Underlying the Association between Endometriosis and Ectopic Pregnancy. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23073490"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ab.2014.09.021","article-title":"Development of surface plasmon resonance imaging biosensors for detection of ubiquitin carboxyl-terminal hydrolase L1","volume":"469","author":"Sankiewicz","year":"2015","journal-title":"Anal. Biochem."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.ejogrb.2013.01.024","article-title":"Determination of cathepsins B, D and G concentration in eutopic proliferative endometrium of women with endometriosis by the surface plasmon resonance imaging (SPRI) technique","volume":"169","author":"Laudanski","year":"2013","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_19","first-page":"148","article-title":"Profiling of peritoneal fluid of women with endometriosis by chemokine protein array","volume":"51","author":"Laudanski","year":"2006","journal-title":"Adv. Med. Sci."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/jog.13559","article-title":"Involvement of immune cells in the pathogenesis of endometriosis","volume":"44","author":"Izumi","year":"2018","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev-pathmechdis-012419-032654","article-title":"The Origin and Pathogenesis of Endometriosis","volume":"15","author":"Wang","year":"2020","journal-title":"Annu. Rev. Pathol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ejogrb.2013.10.007","article-title":"Profiling of selected angiogenesis-related genes in proliferative eutopic endometrium of women with endometriosis","volume":"172","author":"Laudanski","year":"2014","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"5269","DOI":"10.1007\/s00216-016-9621-x","article-title":"SPR imaging biosensor for determination of laminin-5 as a potential cancer marker in biological material","volume":"408","author":"Sankiewicz","year":"2016","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Dalton, C.J., and Lemmon, C.A. (2021). Fibronectin: Molecular Structure, Fibrillar Structure and Mechanochemical Signaling. Cells, 10.","DOI":"10.20944\/preprints202108.0010.v1"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.ctdb.2018.02.002","article-title":"The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate","volume":"130","author":"Muncie","year":"2018","journal-title":"Curr. Top. Dev. Biol."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Musiime, M., Chang, J., Hansen, U., Kadler, K.E., Zeltz, C., and Gullberg, D. (2021). Collagen Assembly at the Cell Surface: Dogmas Revisited. Cells, 10.","DOI":"10.3390\/cells10030662"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1016\/j.bpj.2017.02.027","article-title":"Mechanotransduction Dynamics at the Cell-Matrix Interface","volume":"112","author":"Weinberg","year":"2017","journal-title":"Biophys. J."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/bs.ctdb.2018.02.004","article-title":"Collagen Fibril Assembly and Function","volume":"130","author":"Holmes","year":"2018","journal-title":"Curr. Top. Dev. Biol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/bs.mcb.2017.08.010","article-title":"Basement membrane collagen IV: Isolation of functional domains","volume":"143","author":"Boudko","year":"2018","journal-title":"Methods Cell Biol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/iwj.12109","article-title":"Role of fibronectin in normal wound healing","volume":"12","author":"Lenselink","year":"2015","journal-title":"Int. Wound J."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1146\/annurev-cellbio-100109-104020","article-title":"Assembly of fibronectin extracellular matrix","volume":"26","author":"Singh","year":"2010","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ceb.2016.03.014","article-title":"Collaboration of fibronectin matrix with other extracellular signals in morphogenesis and differentiation","volume":"42","author":"Vega","year":"2016","journal-title":"Curr. Opin. Cell Biol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/cyto.a.20938","article-title":"Using surface plasmon resonance imaging to probe dynamic interactions between cells and extracellular matrix","volume":"77","author":"Peterson","year":"2010","journal-title":"Cytom. A"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"443","DOI":"10.2174\/092986607780782803","article-title":"The Surface Plasmon Resonance Imaging sensor for papain based on immobilized cystatin","volume":"14","author":"Gorodkiewicz","year":"2007","journal-title":"Protein Pept. Lett."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Oldak, L., Chludzinska-Kasperuk, S., Milewska, P., Grubczak, K., Reszec, J., and Gorodkiewicz, E. (2022). Laminin-5, Fibronectin, and Type IV Collagen as Potential Biomarkers of Brain Glioma Malignancy. Biomedicines, 10.","DOI":"10.3390\/biomedicines10092290"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Gorodkiewicz, E., and Lukaszewski, Z. (2018). Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018). Biosensors, 8.","DOI":"10.20944\/preprints201810.0675.v1"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ejogrb.2010.10.026","article-title":"Attachment to extracellular matrices is enhanced in human endometriotic stromal cells: A possible mechanism underlying the pathogenesis of endometriosis","volume":"155","author":"Adachi","year":"2011","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1007\/s10815-020-01905-4","article-title":"GRN, NOTCH3, FN1, and PINK1 expression in eutopic endometrium-potential biomarkers in the detection of endometriosis\u2014A pilot study","volume":"37","author":"Holzer","year":"2020","journal-title":"J. Assist. Reprod. Genet."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Lis-Kuberka, J., Kubik, P., Chrobak, A., Pajak, J., Chelmonska-Soyta, A., and Orczyk-Pawilowicz, M. (2021). Fibronectin Molecular Status in Plasma of Women with Endometriosis and Fertility Disorders. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms222111410"},{"key":"ref_40","first-page":"13","article-title":"Production of fibronectin by peritoneal macrophages and concentration of fibronectin in peritoneal fluid from patients with or without endometriosis","volume":"72","author":"Kauma","year":"1988","journal-title":"Obstet. Gynecol."},{"key":"ref_41","first-page":"111","article-title":"Role of FN1 and GREB1 gene polymorphisms in endometriosis","volume":"20","author":"Matalliotaki","year":"2019","journal-title":"Mol. Med. Rep."},{"key":"ref_42","first-page":"31","article-title":"The role of NADPH-derived reactive oxygen species production in the pathogenesis of endometriosis: A novel mechanistic approach","volume":"30","author":"Nassif","year":"2016","journal-title":"J. Biol. Regul. Homeost. Agents"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S0015-0282(97)81909-7","article-title":"Localization of laminin, fibronectin, E-cadherin, and integrins in endometrium and endometriosis","volume":"67","author":"Beliard","year":"1997","journal-title":"Fertil. Steril."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1046\/j.8755-8920.2003.00129.x","article-title":"The influence of extracellular matrix proteins on T-cell proliferation and apoptosis in women with endometriosis or uterine leiomyoma","volume":"51","author":"Chrobak","year":"2004","journal-title":"Am. J. Reprod. Immunol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.celrep.2018.07.037","article-title":"Clonal Expansion and Diversification of Cancer-Associated Mutations in Endometriosis and Normal Endometrium","volume":"24","author":"Suda","year":"2018","journal-title":"Cell Rep."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s10585-021-10082-2","article-title":"Type IV collagen as a potential biomarker of metastatic breast cancer","volume":"38","author":"Lindgren","year":"2021","journal-title":"Clin. Exp. Metastasis"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1525-1438.2006.00750.x","article-title":"Endometriosis is characterized by an impaired localization of laminin-5 and alpha3beta1 integrin receptor","volume":"17","author":"Giannelli","year":"2007","journal-title":"Int. J. Gynecol. Cancer"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"10","DOI":"10.12701\/yujm.2020.00444","article-title":"Classification of endometriosis","volume":"38","author":"Lee","year":"2021","journal-title":"Yeungnam Univ. J. Med."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.ab.2016.10.002","article-title":"Determination of collagen type IV by Surface Plasmon Resonance Imaging using a specific biosensor","volume":"515","author":"Sankiewicz","year":"2016","journal-title":"Anal. Biochem."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpba.2017.11.070","article-title":"SPR imaging biosensor for the quantitation of fibronectin concentration in blood samples","volume":"150","author":"Sankiewicz","year":"2018","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Falkowski, P., Mrozek, P., Lukaszewski, Z., Oldak, L., and Gorodkiewicz, E. (2021). An Immunosensor for the Determination of Cathepsin S in Blood Plasma by Array SPRi\u2014A Comparison of Analytical Properties of Silver-Gold and Pure Gold Chips. Biosensors, 11.","DOI":"10.3390\/bios11090298"}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/23\/24\/15669\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:37:46Z","timestamp":1760146666000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/23\/24\/15669"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,10]]},"references-count":51,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["ijms232415669"],"URL":"https:\/\/doi.org\/10.3390\/ijms232415669","relation":{},"ISSN":["1422-0067"],"issn-type":[{"value":"1422-0067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,10]]}}}