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To summarize the modern technology and progress in reproductive medicine, all scientific papers related to reproductive medicine, especially papers related to reproductive translational medicine, were fully searched, manually curated and reviewed. Results indicated whether male reproductive medicine or female reproductive medicine all have made significant progress, and their markers have experienced the progress from karyotype analysis to single-cell omics. However, due to the lack of comprehensive databases, especially databases collecting risk exposures, disease markers and models, prevention drugs and effective treatment methods, the application of the latest precision medicine technologies and methods in reproductive medicine is limited.<\/jats:p>","DOI":"10.3390\/ijms24010004","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T03:29:20Z","timestamp":1671506960000},"page":"4","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Translational Bioinformatics for Human Reproductive Biology Research: Examples, Opportunities and Challenges for a Future Reproductive Medicine"],"prefix":"10.3390","volume":"24","author":[{"given":"Kun","family":"Liu","sequence":"first","affiliation":[{"name":"Reproductive Medicine Centre, The First Hospital of Lanzhou University, Lanzhou 730000, China"},{"name":"Biofisika Institute (UPV\/EHU, CSIC), 48940 Leioa, Spain"},{"name":"Department of Biochemistry and Molecular Biology, University of the Basque Country UPV\/EHU, 48080 Bilbao, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5067-1548","authenticated-orcid":false,"given":"Yingbo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institutes for Systems Genetics, West China Hospital Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4087-8729","authenticated-orcid":false,"given":"C\u00e9sar","family":"Martin","sequence":"additional","affiliation":[{"name":"Biofisika Institute (UPV\/EHU, CSIC), 48940 Leioa, Spain"},{"name":"Department of Biochemistry and Molecular Biology, University of the Basque Country UPV\/EHU, 48080 Bilbao, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Ma","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Centre, The First Hospital of Lanzhou University, Lanzhou 730000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bairong","family":"Shen","sequence":"additional","affiliation":[{"name":"Institutes for Systems Genetics, West China Hospital Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.gpb.2016.01.003","article-title":"Translational Bioinformatics: Past, Present, and Future","volume":"14","author":"Tenenbaum","year":"2016","journal-title":"Genom. 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