{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:43:18Z","timestamp":1790660598555,"version":"4.1.0"},"reference-count":37,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,2,19]],"date-time":"2023-02-19T00:00:00Z","timestamp":1676764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the program for fundamental research SSC RF\u2014IBMP RAS","award":["65.4"],"award-info":[{"award-number":["65.4"]}]},{"name":"UNU \u201cTransgenbank\u201d","award":["65.4"],"award-info":[{"award-number":["65.4"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>The impact of weightlessness on the female reproductive system remains poorly understood, although deep space exploration is impossible without the development of effective measures to protect women\u2019s health. The purpose of this work was to study the effect of a 5-day \u201cdry\u201d immersion on the state of the reproductive system of female subjects. On the fourth day of the menstrual cycle after immersion, we observed an increase in inhibin B of 35% (p &lt; 0.05) and a decrease in luteinizing hormone of 12% (p &lt; 0.05) and progesterone of 52% (p &lt; 0.05) compared with the same day before immersion. The size of the uterus and the thickness of the endometrium did not change. On the ninth day of the menstrual cycle after immersion, the average diameters of the antral follicles and the dominant follicle were, respectively, 14% and 22% (p &lt; 0.05) higher than before. The duration of the menstrual cycle did not change. The obtained results may indicate that the stay in the 5-day \u201cdry\u201d immersion, on the one hand, can stimulate the growth of the dominant follicle, but, on the other hand, can cause functional insufficiency of the corpus lutea.<\/jats:p>","DOI":"10.3390\/ijms24044160","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T04:28:57Z","timestamp":1676867337000},"page":"4160","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The State of the Organs of the Female Reproductive System after a 5-Day \u201cDry\u201d Immersion"],"prefix":"10.3390","volume":"24","author":[{"given":"Elena Yu.","family":"Gorbacheva","sequence":"first","affiliation":[{"name":"Cell Biophysics Laboratory, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia"},{"name":"Gynecology Department, FGBU KB1 (Volynskaya) UDP RF, 121352 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantin A.","family":"Toniyan","sequence":"additional","affiliation":[{"name":"Cell Biophysics Laboratory, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia"},{"name":"Gynecology Department, FGBU KB1 (Volynskaya) UDP RF, 121352 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulia A.","family":"Biriukova","sequence":"additional","affiliation":[{"name":"Gynecology Department, FGBU KB1 (Volynskaya) UDP RF, 121352 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadezhda A.","family":"Lukicheva","sequence":"additional","affiliation":[{"name":"Cell Biophysics Laboratory, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleg I.","family":"Orlov","sequence":"additional","affiliation":[{"name":"Cell Biophysics Laboratory, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valery V.","family":"Boyarintsev","sequence":"additional","affiliation":[{"name":"Emergency and Extreme Medicine Department, FGBU DPO CGMA UDP RF, 121359 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0125-5876","authenticated-orcid":false,"given":"Irina V.","family":"Ogneva","sequence":"additional","affiliation":[{"name":"Cell Biophysics Laboratory, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1089\/jwh.2014.4915","article-title":"Effects of sex and gender on adaptations to space: Reproductive health","volume":"23","author":"Ronca","year":"2014","journal-title":"J. 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