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University","award":["2022CYZC-47"],"award-info":[{"award-number":["2022CYZC-47"]}]},{"name":"Funding for Discipline team Construction of Gansu Agricultural University","award":["LCJ20210020"],"award-info":[{"award-number":["LCJ20210020"]}]},{"name":"Funding for Discipline team Construction of Gansu Agricultural University","award":["2500011004"],"award-info":[{"award-number":["2500011004"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Seasonal reproduction is a survival strategy by which animals adapt to environmental changes to improve their fitness. Males are often characterized by a significantly reduced testicular volume, indicating that they are in an immature state. Although many hormones, including gonadotropins, have played a role in testicular development and spermatogenesis, research on other hormones is insufficient. The anti-M\u00fcllerian hormone (AMH), which is a hormone responsible for inducing the regression of M\u00fcllerian ducts involved in male sex differentiation, was discovered in 1953. Disorders in AMH secretion are the main biomarkers of gonadal dysplasia, indicating that it may play a crucial role in reproduction regulation. A recent study has found that the AMH protein is expressed at a high level during the non-breeding period of seasonal reproduction in animals, implying that it may play a role in restricting breeding activities. In this review, we summarize the research progress on the AMH gene expression, regulatory factors of the gene\u2019s expression, and its role in reproductive regulation. Using males as an example, we combined testicular regression and the regulatory pathway of seasonal reproduction and attempted to identify the potential relationship between AMH and seasonal reproduction, to broaden the physiological function of AMH in reproductive suppression, and to provide new ideas for understanding the regulatory pathway of seasonal reproduction.<\/jats:p>","DOI":"10.3390\/ijms24065874","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T06:48:35Z","timestamp":1679294915000},"page":"5874","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Potential Role of Anti-M\u00fcllerian Hormone in Regulating Seasonal Reproduction in Animals: The Example of Males"],"prefix":"10.3390","volume":"24","author":[{"given":"Kang","family":"An","sequence":"first","affiliation":[{"name":"Key Laboratory of Grassland Ecosystem, Ministry of Education, College of Grassland Science, Gansu Agricultural University, Lanzhou 730070, China"},{"name":"Massey University Research Centre for Grassland Biodiversity, Gansu Agricultural University, Lanzhou 730070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baohui","family":"Yao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Grassland Ecosystem, Ministry of Education, College of Grassland Science, Gansu Agricultural University, Lanzhou 730070, China"},{"name":"Massey University Research Centre for Grassland Biodiversity, Gansu Agricultural University, Lanzhou 730070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchen","family":"Tan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Grassland Ecosystem, Ministry of Education, College of Grassland Science, Gansu Agricultural University, Lanzhou 730070, China"},{"name":"Massey University Research Centre for Grassland Biodiversity, Gansu Agricultural University, Lanzhou 730070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukun","family":"Kang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Grassland Ecosystem, Ministry of Education, College of Grassland Science, Gansu Agricultural University, Lanzhou 730070, China"},{"name":"Massey University Research Centre for Grassland Biodiversity, Gansu Agricultural University, Lanzhou 730070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhu","family":"Su","sequence":"additional","affiliation":[{"name":"Key Laboratory of Grassland Ecosystem, Ministry of Education, College of Grassland Science, Gansu Agricultural University, Lanzhou 730070, China"},{"name":"Massey University Research Centre for Grassland Biodiversity, Gansu Agricultural University, Lanzhou 730070, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"R117","DOI":"10.1530\/JOE-16-0066","article-title":"Molecular basis for regulating seasonal reproduction in vertebrates","volume":"229","author":"Yoshimura","year":"2016","journal-title":"J. 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