{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T19:04:26Z","timestamp":1766689466391,"version":"build-2065373602"},"reference-count":42,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T00:00:00Z","timestamp":1683590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research, Development and Innovation Fund of Hungary","award":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"],"award-info":[{"award-number":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"]}]},{"DOI":"10.13039\/501100018818","name":"National Research, Development and Innovation Office","doi-asserted-by":"publisher","award":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"],"award-info":[{"award-number":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"]}],"id":[{"id":"10.13039\/501100018818","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Pecs Medical School","award":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"],"award-info":[{"award-number":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"]}]},{"name":"Hungarian Academy of Sciences","award":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"],"award-info":[{"award-number":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"]}]},{"name":"National Research, Development and Innovation Fund","award":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"],"award-info":[{"award-number":["2020-4.1.1-TKP2020","NKFIH K119529","KA-2021-20"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Preeclampsia is the leading cause of complicated neonatal adaptation. The present investigation aimed to study the hemorheological factors during the early perinatal period (cord blood, 24 and 72 h after delivery) in newborns of early-onset preeclamptic mothers (n = 13) and healthy neonates (n = 17). Hematocrit, plasma, and whole blood viscosity (WBV), red blood cell (RBC) aggregation, and deformability were investigated. There were no significant differences in hematocrit. WBV was significantly lower in preterm neonates at birth than in the term 24 and 72 h samples. Plasma viscosity was significantly lower in preterm neonates\u2019 cord blood than in healthy controls. RBC aggregation parameters were significantly lower in preterm newborns\u2019 cord blood than in term neonates\u2019 cord blood 24 and 72 h samples. RBC elongation indices were significantly lower in the term group than in preterm neonates 72 h\u2019 sample at the high and middle shear stress range. Changes in the hemorheological parameters, especially RBC aggregation properties, refer to better microcirculation of preterm neonates at birth, which could be an adaptation mechanism to the impaired uteroplacental microcirculation in preeclampsia.<\/jats:p>","DOI":"10.3390\/ijms24108496","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T03:32:27Z","timestamp":1683689547000},"page":"8496","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Influence of Early Onset Preeclampsia on Perinatal Red Blood Cell Characteristics of Neonates"],"prefix":"10.3390","volume":"24","author":[{"given":"Barbara","family":"Sandor","sequence":"first","affiliation":[{"name":"1st Department of Medicine, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5537-9738","authenticated-orcid":false,"given":"Beata","family":"Csiszar","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Therapy, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gergely","family":"Galos","sequence":"additional","affiliation":[{"name":"1st Department of Medicine, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Funke","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dora Kinga","family":"Kevey","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9913-2024","authenticated-orcid":false,"given":"Matyas","family":"Meggyes","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunology, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1208-2969","authenticated-orcid":false,"given":"Laszlo","family":"Szereday","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunology, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0114-5231","authenticated-orcid":false,"given":"Kalman","family":"Toth","sequence":"additional","affiliation":[{"name":"1st Department of Medicine, Medical School, University of P\u00e9cs, 7624 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.ajog.2005.10.813","article-title":"Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions?","volume":"194","author":"Villar","year":"2006","journal-title":"Am. 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