{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:09:56Z","timestamp":1760148596335,"version":"build-2065373602"},"reference-count":48,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"UAE University","award":["12M106","31M491"],"award-info":[{"award-number":["12M106","31M491"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Cardiovascular disease (CVD) during pregnancy varies significantly worldwide, influenced by factors such as access to healthcare, delayed diagnosis, causes, and risk factors. Our study sought to explore the spectrum of CVD present in pregnant women in the United Arab Emirates to better understand this population\u2019s unique needs and challenges. Central to our study is an emphasis on the importance of implementing a multidisciplinary approach that involves the collaboration of obstetricians, cardiologists, geneticists, and other healthcare professionals to ensure that patients receive comprehensive and coordinated care. This approach can also help identify high-risk patients and implement preventive measures to reduce the occurrence of adverse maternal outcomes. Furthermore, increasing awareness among women about the risk of CVD during pregnancy and obtaining detailed family histories can help in the early identification and management of these conditions. Genetic testing and family screening can also aid in identifying inherited CVD that can be passed down through families. To illustrate the significance of such an approach, we provide a comprehensive analysis of five women\u2019s cases from our retrospective study of 800 women. The findings from our study emphasize the importance of addressing maternal cardiac health in pregnancy and the need for targeted interventions and improvements in the existing healthcare system to reduce adverse maternal outcomes.<\/jats:p>","DOI":"10.3390\/ijms24119119","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T03:20:06Z","timestamp":1684812006000},"page":"9119","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Introducing and Implementing Genetic Assessment in Cardio-Obstetrics Clinical Practice: Clinical and Genetic Workup of Patients with Cardiomyopathy"],"prefix":"10.3390","volume":"24","author":[{"given":"Ghadeera Al","family":"Mansoori","sequence":"first","affiliation":[{"name":"Department of Cardiology, Sheikh Shakhbout Medical City, Abu Dhabi 11001, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0312-9910","authenticated-orcid":false,"given":"Wael Al","family":"Mahmeed","sequence":"additional","affiliation":[{"name":"Heart, Vascular & Thoracic Institute, Cleveland Clinic, Abu Dhabi 112412, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saleema","family":"Wani","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Corniche Hospital, Abu Dhabi 3788, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bashir Taha","family":"Salih","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Corniche Hospital, Abu Dhabi 3788, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9129-2353","authenticated-orcid":false,"given":"Tarek El","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Corniche Hospital, Abu Dhabi 3788, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fathima","family":"Farook","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Corniche Hospital, Abu Dhabi 3788, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zenab","family":"Farooq","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Sciences, Khalifa University, Abu Dhabi 127788, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howaida","family":"Khair","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8262-4380","authenticated-orcid":false,"given":"Kornelia","family":"Zar\u0119ba","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nahid Al","family":"Dhahouri","sequence":"additional","affiliation":[{"name":"Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6704-8350","authenticated-orcid":false,"given":"Anjana","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger S.","family":"Foo","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Institute, National University Healthcare Systems, Singapore 117599, Singapore"},{"name":"Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore 138672, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1306-6618","authenticated-orcid":false,"given":"Bassam R.","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma Al","family":"Jasmi","sequence":"additional","affiliation":[{"name":"Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6311-7028","authenticated-orcid":false,"given":"Nadia","family":"Akawi","sequence":"additional","affiliation":[{"name":"Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates"},{"name":"Division of Cardiovascular Medicine, University of Oxford, Oxford OX3 9DU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,23]]},"reference":[{"key":"ref_1","first-page":"e6034","article-title":"Twenty-Eight Pregnant Women with Cardiac Diseases: A Review of Maternal and Fetal Outcomes in Pakistan","volume":"11","author":"Soomro","year":"2019","journal-title":"Cureus"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e017832","DOI":"10.1161\/JAHA.120.017832","article-title":"Disparities in 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