{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:51:34Z","timestamp":1791982294977,"version":"4.4.0"},"reference-count":139,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Key R &amp; D Program of China","award":["2021YFD1400800"],"award-info":[{"award-number":["2021YFD1400800"]}]},{"name":"National Key R &amp; D Program of China","award":["QKHJC-ZK (2022)039"],"award-info":[{"award-number":["QKHJC-ZK (2022)039"]}]},{"name":"National Key R &amp; D Program of China","award":["2022115"],"award-info":[{"award-number":["2022115"]}]},{"name":"Natural Science Foundation of Guizhou Province","award":["2021YFD1400800"],"award-info":[{"award-number":["2021YFD1400800"]}]},{"name":"Natural Science Foundation of Guizhou Province","award":["QKHJC-ZK (2022)039"],"award-info":[{"award-number":["QKHJC-ZK (2022)039"]}]},{"name":"Natural Science Foundation of Guizhou Province","award":["2022115"],"award-info":[{"award-number":["2022115"]}]},{"name":"Scientific Research Project of Guizhou Provincial Education Department (Young Project)","award":["2021YFD1400800"],"award-info":[{"award-number":["2021YFD1400800"]}]},{"name":"Scientific Research Project of Guizhou Provincial Education Department (Young Project)","award":["QKHJC-ZK (2022)039"],"award-info":[{"award-number":["QKHJC-ZK (2022)039"]}]},{"name":"Scientific Research Project of Guizhou Provincial Education Department (Young Project)","award":["2022115"],"award-info":[{"award-number":["2022115"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Benzoxazole and benzothiazole have a broad spectrum of agricultural biological activities, such as antibacterial, antiviral, and herbicidal activities, which are important fused heterocyclic scaffold structures in agrochemical discovery. In recent years, great progress has been made in the research of benzoxazoles and benzothiazoles, especially in the development of herbicides and insecticides. With the widespread use of benzoxazoles and benzothiazoles, there may be more new products containing benzoxazoles and benzothiazoles in the future. We systematically reviewed the application of benzoxazoles and benzothiazoles in discovering new agrochemicals in the past two decades and summarized the antibacterial, fungicidal, antiviral, herbicidal, and insecticidal activities of the active compounds. We also discussed the structural\u2013activity relationship and mechanism of the active compounds. This work aims to provide inspiration and ideas for the discovery of new agrochemicals based on benzoxazole and benzothiazole.<\/jats:p>","DOI":"10.3390\/ijms241310807","type":"journal-article","created":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T00:41:45Z","timestamp":1687999305000},"page":"10807","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Research Progress of Benzothiazole and Benzoxazole Derivatives in the Discovery of Agricultural Chemicals"],"prefix":"10.3390","volume":"24","author":[{"given":"Yue","family":"Zou","sequence":"first","affiliation":[{"name":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Liu","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyi","family":"Song","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingfeng","family":"Cai","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Wang","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chongfen","family":"Yi","sequence":"additional","affiliation":[{"name":"Guizhou Rice Research Institute, Guizhou Academy of Agricultural Sciences, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jixiang","family":"Chen","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1146\/annurev.phyto.43.113004.133839","article-title":"Plant disease: A threat to global food security","volume":"43","author":"Strange","year":"2005","journal-title":"Annu. 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