{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:04:29Z","timestamp":1792789469194,"version":"4.5.0"},"reference-count":100,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T00:00:00Z","timestamp":1694822400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Italian Ministry of Health","award":["RC-2023-2778976"],"award-info":[{"award-number":["RC-2023-2778976"]}]},{"name":"Italian Ministry of Health","award":["RBFR12D1CB"],"award-info":[{"award-number":["RBFR12D1CB"]}]},{"name":"FIRB Futura","award":["RC-2023-2778976"],"award-info":[{"award-number":["RC-2023-2778976"]}]},{"name":"FIRB Futura","award":["RBFR12D1CB"],"award-info":[{"award-number":["RBFR12D1CB"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Peripheral T-cell lymphomas (PTCLs) are a rare subset of non-Hodgkin lymphomas that often carry significant difficulty in diagnosis and classification because of their rarity and biological complexity. Previous editions of the World Health Organization (WHO) classifications of hemopoietic neoplasms in 2001, 2008, and 2017 aimed to standardize hemopoietic neoplasm diagnosis in general. Since then, crucial clinico-pathological, immunophenotypic, and recent molecular discoveries have been made in the field of lymphomas, contributing to refining diagnostic criteria of several diseases, upgrading entities previously defined as provisional, and identifying new entities. In 2022, two different models were proposed to classify hematolymphoid neoplasms: the 5th edition of the WHO classification (WHO-HAEM5) and the International Consensus Classification (ICC). Of note, a common nosography is mandatory to ensure progress in health science and ensure the basis for a real precision medicine. In this article, the authors summarized the main differences with the previous fourth WHO edition and reviewed the main discrepancies between the two newest classifications, as far as PTCLs are concerned.<\/jats:p>","DOI":"10.3390\/ijms241814170","type":"journal-article","created":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T06:12:21Z","timestamp":1694931141000},"page":"14170","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["A Comparison of the Fifth World Health Organization and the International Consensus Classifications of Mature T-Cell Lymphomas"],"prefix":"10.3390","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9432-0595","authenticated-orcid":false,"given":"Pier Paolo","family":"Piccaluga","sequence":"first","affiliation":[{"name":"Biobank of Research, IRCCS Azienda Opedaliera-Universitaria di Bologna, 40138 Bologna, Italy"},{"name":"Department of Medical and Surgical Sciences, Bologna University School of Medicine, 40138 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3212-5081","authenticated-orcid":false,"given":"Shaimaa S.","family":"Khattab","sequence":"additional","affiliation":[{"name":"Medical Research Institute, Hematology Department, Alexandria University, Alexandria 5310002, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,16]]},"reference":[{"key":"ref_1","first-page":"4384","article-title":"Classification of lymphoid neoplasms: The microscope as a tool for disease discovery","volume":"112","author":"Jaffe","year":"2008","journal-title":"Blood J. 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