{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T21:08:03Z","timestamp":1788901683469,"version":"build-2803163510"},"reference-count":194,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T00:00:00Z","timestamp":1699056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research Grants Council (RGC) of Hong Kong","award":["T13-602\/21-N"],"award-info":[{"award-number":["T13-602\/21-N"]}]},{"name":"Research Grants Council (RGC) of Hong Kong","award":["KJQN202000408"],"award-info":[{"award-number":["KJQN202000408"]}]},{"name":"Scientific and Technological Research Program of Chongqing Municipal Education Commission","award":["T13-602\/21-N"],"award-info":[{"award-number":["T13-602\/21-N"]}]},{"name":"Scientific and Technological Research Program of Chongqing Municipal Education Commission","award":["KJQN202000408"],"award-info":[{"award-number":["KJQN202000408"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Endometriosis, a prevalent disorder in women of reproductive age, is often associated with undesired infertility. Ovarian reserve, an essential measure of ovarian function that is crucial for maintaining fecundity, is frequently diminished in women with endometriosis. Though the causative relationship between endometriosis and reduced ovarian reserve is not fully understood due to the lack of standardized and precise measurements of ovarian reserve, there is ongoing discussion regarding the impact of interventions for endometriosis on ovarian reserve. Therefore, in this review, we investigate articles that have related keywords and which were also published in recent years. Thereafter, we provide a comprehensive summary of evidence from in vitro, in vivo, and human studies, thereby shedding light on the decreased ovarian reserve in endometriosis. This research consolidates evidence from in vitro, in vivo, and human studies on the diminished ovarian reserve associated with endometriosis, as well as enhances our understanding of whether and how endometriosis, as well as its interventions, contribute to reductions in ovarian reserve. Furthermore, we explore potential strategies to modify existing therapy options that could help prevent diminished ovarian reserve in patients with endometriosis.<\/jats:p>","DOI":"10.3390\/ijms242115967","type":"journal-article","created":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T14:51:01Z","timestamp":1699109461000},"page":"15967","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Diminished Ovarian Reserve in Endometriosis: Insights from In Vitro, In Vivo, and Human Studies\u2014A Systematic Review"],"prefix":"10.3390","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5446-2273","authenticated-orcid":false,"given":"Zhouyurong","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0069-2599","authenticated-orcid":false,"given":"Xue","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China"},{"name":"Department of Obstetrics and Gynaecology, The Second Affiliated Hospital, The Chinese University of Hong Kong, Shenzhen 518172, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3928-7278","authenticated-orcid":false,"given":"Chi Chiu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China"},{"name":"School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China"},{"name":"Chinese University of Hong Kong-Sichuan University Joint Laboratory in Reproductive Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China"},{"name":"Reproduction and Development, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5737-4498","authenticated-orcid":false,"given":"Jin","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China"},{"name":"Department of Obstetrics and Gynaecology, The Second Affiliated Hospital, The Chinese University of Hong Kong, Shenzhen 518172, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s13669-017-0187-1","article-title":"Endometriosis: Epidemiology, Diagnosis and Clinical Management","volume":"6","author":"Parasar","year":"2017","journal-title":"Curr. Obs. Gynecol. Rep."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1056\/NEJMra0804690","article-title":"Endometriosis","volume":"360","author":"Bulun","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"The Practice Committee of the American Society for Reproductive Medicine (2012). Testing and interpreting measures of ovarian reserve: A committee opinion. Fertil. Steril., 98, 1407\u20131415.","DOI":"10.1016\/j.fertnstert.2012.09.036"},{"key":"ref_4","unstructured":"The Practice Committee of the American Society for Reproductive Medicine (2020). Testing and interpreting measures of ovarian reserve: A committee opinion. Fertil. Steril., 114, 1151\u20131157."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3109\/00365513.2014.936674","article-title":"The regulation and assessment of follicular growth","volume":"244","author":"Dunlop","year":"2014","journal-title":"Scand. J. Clin. Lab. Investig."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Jones, R.E., and Lopez, K.H. (2013). Human Reproductive Biology, Academic Press. [4th ed.].","DOI":"10.1016\/B978-0-12-382184-3.00007-6"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s13048-023-01151-z","article-title":"Mechanisms of ovarian aging in women: A review","volume":"16","author":"Wang","year":"2023","journal-title":"J. Ovarian Res."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1073261","DOI":"10.3389\/fendo.2022.1073261","article-title":"Impacts of endometrioma on ovarian aging from basic science to clinical management","volume":"13","author":"Tan","year":"2022","journal-title":"Front. Endocrinol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s10815-014-0415-9","article-title":"Knowledge of ovarian reserve and reproductive choices","volume":"32","author":"Azhar","year":"2015","journal-title":"J. Assist. Reprod. Genet."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1055\/s-0035-1567820","article-title":"The Impact of Endometriosis and Its Treatment on Ovarian Reserve","volume":"33","author":"Seyhan","year":"2015","journal-title":"Semin. Reprod. Med."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Moher, D., Liberati, A., Tetzlaff, J., and Altman, D.G. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Med., 6.","DOI":"10.1371\/journal.pmed.1000097"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Tan, Z., Hung, S.W., Zheng, X., Wang, C.C., Chung, J.P., and Zhang, T. (2022). What We Have Learned from Animal Models to Understand the Etiology and Pathology of Endometrioma-Related Infertility. Biomedicines, 10.","DOI":"10.3390\/biomedicines10071483"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.25122\/jml-2021-0391","article-title":"The effect of endometriosis on fertility in an animal model","volume":"15","author":"Kanellopoulos","year":"2022","journal-title":"J. Med. Life"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Park, Y., Cho, Y.J., Sung, N., Park, M.J., Guan, X., Gibbons, W.E., O\u2019Malley, B.W., and Han, S.J. (2022). Oleuropein suppresses endometriosis progression and improves the fertility of mice with endometriosis. J. Biomed. Sci., 29.","DOI":"10.1186\/s12929-022-00883-2"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Hayashi, S., Nakamura, T., Motooka, Y., Ito, F., Jiang, L., Akatsuka, S., Iwase, A., Kajiyama, H., Kikkawa, F., and Toyokuni, S. (2020). Novel ovarian endometriosis model causes infertility via iron-mediated oxidative stress in mice. Redox Biol., 37.","DOI":"10.1016\/j.redox.2020.101726"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"5547","DOI":"10.1210\/jc.2019-00281","article-title":"Endometriosis Triggers Excessive Activation of Primordial Follicles via PI3K-PTEN-Akt-Foxo3 Pathway","volume":"104","author":"Takeuchi","year":"2019","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1055\/s-0042-115566","article-title":"Everolimus as an mTOR Inhibitor Suppresses Endometriotic Implants: An Experimental Rat Study","volume":"77","author":"Kacan","year":"2017","journal-title":"Geburtshilfe Frauenheilkde"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1177\/1933719112452941","article-title":"The efficacy of bevacizumab, sorafenib, and retinoic acid on rat endometriosis model","volume":"20","author":"Ozer","year":"2013","journal-title":"Reprod. Sci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1095\/biolreprod.109.083287","article-title":"Neutralizing TIMP1 restores fecundity in a rat model of endometriosis and treating control rats with TIMP1 causes anomalies in ovarian function and embryo development","volume":"83","author":"Stilley","year":"2010","journal-title":"Biol. Reprod."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1095\/biolreprod.108.073411","article-title":"Reduced fecundity in female rats with surgically induced endometriosis and in their daughters: A potential role for tissue inhibitors of metalloproteinase 1","volume":"80","author":"Stilley","year":"2009","journal-title":"Biol. Reprod."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0015-0282(16)58641-5","article-title":"The cycle pregnancy rate is normal in baboons with stage I endometriosis but decreased in primates with stage II and stage III\u2013IV disease","volume":"66","author":"Bambra","year":"1996","journal-title":"Fertil. Steril."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/S0015-0282(16)55572-1","article-title":"Experimentally induced endometriosis in rats: Effect on fertility and the effects of pregnancy and lactation on the ectopic endometrial tissue","volume":"58","author":"Barragan","year":"1992","journal-title":"Fertil. Steril."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1749-6632.1991.tb37868.x","article-title":"Experimental endometriosis in monkeys","volume":"622","author":"Schenken","year":"1991","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Muraoka, A., Osuka, S., Yabuki, A., Yoshihara, M., Tanaka, H., Sonehara, R., Miyake, N., Murakami, M., and Yoshita, S. (2021). Impact of perioperative use of GnRH agonist or dienogest on ovarian reserve after cystectomy for endometriomas: A randomized controlled trial. Reprod. Biol. Endocrinol., 19.","DOI":"10.1186\/s12958-021-00866-2"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"56","DOI":"10.4103\/jhrs.JHRS_94_20","article-title":"Effect of Laparoscopic Ovarian Cystectomy on Ovarian Reserve in Benign Ovarian Cysts","volume":"14","author":"Sireesha","year":"2021","journal-title":"J. Hum. Reprod. Sci."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.rbmo.2020.07.022","article-title":"Pretreatment with dienogest in women with endometriosis undergoing IVF after a previous failed cycle","volume":"41","author":"Barra","year":"2020","journal-title":"Reprod. Biomed. Online"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1080\/01443615.2019.1633518","article-title":"The effects of endometrioma size and bilaterality on ovarian reserve","volume":"40","author":"Karadag","year":"2020","journal-title":"J. Obstet. Gynaecol."},{"key":"ref_28","first-page":"2205","article-title":"Assessment of ovarian reserve after cystectomy versus \u2018one-step\u2019 laser vaporization in the treatment of ovarian endometrioma: A small randomized clinical trial","volume":"33","author":"Candiani","year":"2018","journal-title":"Hum. Reprod."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.fertnstert.2018.03.015","article-title":"Endometrioma-related reduction in ovarian reserve (ERROR): A prospective longitudinal study","volume":"110","author":"Kasapoglu","year":"2018","journal-title":"Fertil. Steril."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1080\/09513590.2017.1415676","article-title":"Dienogest treatment after ovarian endometrioma removal in infertile women prior to IVF","volume":"33","author":"Muller","year":"2017","journal-title":"Gynecol. Endocrinol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ejogrb.2015.06.006","article-title":"Effects of low dose oral contraceptive pill containing drospirenone\/ethinylestradiol in patients with endometrioma","volume":"191","author":"Taniguchi","year":"2015","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/uog.14763","article-title":"Assessment of ovarian reserve by antral follicle count in ovaries with endometrioma","volume":"46","author":"Lima","year":"2015","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/j.fertnstert.2008.08.071","article-title":"The impact of electrocoagulation on ovarian reserve after laparoscopic excision of ovarian cysts: A prospective clinical study of 191 patients","volume":"92","author":"Li","year":"2009","journal-title":"Fertil. Steril."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Khan, H.L., Bhatti, S., Suhail, S., Gul, R., Awais, A., Hamayun, H., Enver, F., Abbas, S., Hassan, Z., and Nisar, R. (2019). Antral follicle count (AFC) and serum anti-M\u00fcllerian hormone (AMH) are the predictors of natural fecundability have similar trends irrespective of fertility status and menstrual characteristics among fertile and infertile women below the age of 40 years. Reprod. Biol. Endocrinol., 17.","DOI":"10.1186\/s12958-019-0464-0"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/uog.18945","article-title":"Counting ovarian antral follicles by ultrasound: A practical guide","volume":"51","author":"Ludwin","year":"2018","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1196\/annals.1335.032","article-title":"Endometriosis and inflammation in infertility","volume":"1034","author":"Halis","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/j.ejrad.2014.04.032","article-title":"Basics, principles, techniques and modern methods in paediatric ultrasonography","volume":"83","author":"Riccabona","year":"2014","journal-title":"Eur. J. Radiol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1038\/s12276-022-00858-1","article-title":"A novel role of follicle-stimulating hormone (FSH) in various regeneration-related functions of endometrial stem cells","volume":"54","author":"Park","year":"2022","journal-title":"Exp. Mol. Med."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Leung, P.C.K., Armstrong, D.T., Ruf, K.B., Moger, W.H., and Friesen, H.G. (1987). Endocrinology and Physiology of Reproduction, Springer.","DOI":"10.1007\/978-1-4899-1971-7"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1677\/joe.1.06614","article-title":"Follicle-stimulating hormone increases primordial follicle reserve in mature female hypogonadal mice","volume":"188","author":"Allan","year":"2006","journal-title":"J. Endocrinol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.fertnstert.2007.06.023","article-title":"Serum antim\u00fcllerian hormone levels remain stable throughout the menstrual cycle and after oral or vaginal administration of synthetic sex steroids","volume":"90","author":"Streuli","year":"2008","journal-title":"Fertil. Steril."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Arslan, A.A., Zeleniuch-Jacquotte, A., Lukanova, A., Rinaldi, S., Kaaks, R., and Toniolo, P. (2003). Reliability of follicle-stimulating hormone measurements in serum. Reprod. Biol. Endocrinol., 1.","DOI":"10.1186\/1477-7827-1-49"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"108","DOI":"10.4103\/0974-1208.92283","article-title":"Ovarian reserve tests","volume":"4","author":"Jirge","year":"2011","journal-title":"J. Hum. Reprod. Sci."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/GCO.0000000000000536","article-title":"Diminished ovarian reserve versus ovarian aging: Overlaps and differences","volume":"31","author":"Ata","year":"2019","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/molehr\/gah015","article-title":"Anti-M\u00fcllerian hormone expression pattern in the human ovary: Potential implications for initial and cyclic follicle recruitment","volume":"10","author":"Weenen","year":"2004","journal-title":"Mol. Hum. Reprod."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/molehr\/gat024","article-title":"Which follicles make the most anti-Mullerian hormone in humans? Evidence for an abrupt decline in AMH production at the time of follicle selection","volume":"19","author":"Jeppesen","year":"2013","journal-title":"Mol. Hum. Reprod."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1210\/endo.143.3.8691","article-title":"Anti-M\u00fcllerian hormone inhibits initiation of primordial follicle growth in the mouse ovary","volume":"143","author":"Durlinger","year":"2002","journal-title":"Endocrinology"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0015-0282(99)00639-1","article-title":"Serum m\u00fcllerian-inhibiting substance levels during normal menstrual cycles","volume":"73","author":"Cook","year":"2000","journal-title":"Fertil. Steril."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/humrep\/dep366","article-title":"Comparison of inter- and intra-cycle variability of anti-Mullerian hormone and antral follicle counts","volume":"25","author":"Lambalk","year":"2010","journal-title":"Hum. Reprod."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.fertnstert.2013.04.024","article-title":"Prediction of an excessive response in in vitro fertilization from patient characteristics and ovarian reserve tests and comparison in subgroups: An individual patient data meta-analysis","volume":"100","author":"Broer","year":"2013","journal-title":"Fertil. Steril."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0015-0282(01)02993-4","article-title":"Antimullerian hormone serum levels: A putative marker for ovarian aging","volume":"77","author":"Laven","year":"2002","journal-title":"Fertil. Steril."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1093\/humupd\/dmu062","article-title":"Technical and performance characteristics of anti-M\u00fcllerian hormone and antral follicle count as biomarkers of ovarian response","volume":"21","author":"Iliodromiti","year":"2015","journal-title":"Hum. Reprod. Update"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"3085","DOI":"10.1093\/humrep\/des260","article-title":"Anti-Mullerian hormone: Poor assay reproducibility in a large cohort of subjects suggests sample instability","volume":"27","author":"Rustamov","year":"2012","journal-title":"Hum. Reprod."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.fertnstert.2014.10.037","article-title":"What is the \u201covarian reserve\u201d?","volume":"103","author":"Findlay","year":"2015","journal-title":"Fertil. Steril."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"3228","DOI":"10.1210\/en.2005-1588","article-title":"Serum Anti-M\u00fcllerian Hormone Levels Reflect the Size of the Primordial Follicle Pool in Mice","volume":"147","author":"Kevenaar","year":"2006","journal-title":"Endocrinology"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1530\/rep.1.00095","article-title":"Methods for quantifying follicular numbers within the mouse ovary","volume":"127","author":"Myers","year":"2004","journal-title":"Reproduction"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"13499","DOI":"10.1038\/s41598-018-31883-8","article-title":"High-throughput ovarian follicle counting by an innovative deep learning approach","volume":"8","author":"Sonigo","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.2527\/jas.2013-6233","article-title":"Triennial Reproduction Symposium: The ovarian follicular reserve in cattle: What regulates its formation and size?","volume":"91","author":"Fortune","year":"2013","journal-title":"J. Anim. Sci."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1159\/000495895","article-title":"Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation","volume":"51","author":"Nie","year":"2018","journal-title":"Cell Physiol. Biochem."},{"key":"ref_60","unstructured":"Tulandi, T.G.R. (2004). Preservation of Fertility, Taylor and Francis."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/humrep\/dew330","article-title":"Inter-observer and intra-observer agreement between embryologists during selection of a single Day 5 embryo for transfer: A multicenter study","volume":"32","author":"Storr","year":"2017","journal-title":"Hum. Reprod."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1093\/humrep\/dew183","article-title":"Correlation between aneuploidy, standard morphology evaluation and morphokinetic development in 1730 biopsied blastocysts: A consecutive case series study","volume":"31","author":"Minasi","year":"2016","journal-title":"Hum. Reprod."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.molcel.2018.10.029","article-title":"Transcriptome Landscape of Human Folliculogenesis Reveals Oocyte and Granulosa Cell Interactions","volume":"72","author":"Zhang","year":"2018","journal-title":"Mol. Cell"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1007\/s10815-016-0782-5","article-title":"Intrafollicular interleukin-8, interleukin-12, and adrenomedullin are the promising prognostic markers of oocyte and embryo quality in women with endometriosis","volume":"33","author":"Singh","year":"2016","journal-title":"J. Assist. Reprod. Genet."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"e32757","DOI":"10.1097\/MD.0000000000032757","article-title":"The effect of individual oocyte matched follicular fluid oxidant, antioxidant status, and pro- and anti-inflammatory cytokines on IVF outcomes of patients with diminished ovarian reserve","volume":"102","author":"Ilhan","year":"2023","journal-title":"Medicine"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.rbmo.2020.09.014","article-title":"Antral follicle count is reduced in the presence of endometriosis: A systematic review and meta-analysis","volume":"42","author":"Tian","year":"2021","journal-title":"Reprod. Biomed. Online"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1093\/humrep\/deu199","article-title":"The effect of surgery for endometrioma on ovarian reserve evaluated by antral follicle count: A systematic review and meta-analysis","volume":"29","author":"Muzii","year":"2014","journal-title":"Hum. Reprod."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.fertnstert.2018.06.025","article-title":"Antimullerian hormone is reduced in the presence of ovarian endometriomas: A systematic review and meta-analysis","volume":"110","author":"Muzii","year":"2018","journal-title":"Fertil. Steril."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"e070750","DOI":"10.1136\/bmj-2022-070750","article-title":"Pathophysiology, diagnosis, and management of endometriosis","volume":"379","author":"Horne","year":"2022","journal-title":"BMJ"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/S0140-6736(21)00389-5","article-title":"Endometriosis is a chronic systemic disease: Clinical challenges and novel innovations","volume":"397","author":"Taylor","year":"2021","journal-title":"Lancet"},{"key":"ref_71","unstructured":"NICE (2017). Endometriosis: Diagnosis and Management, National Institute for Health and Care Excellence."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"hoac009","DOI":"10.1093\/hropen\/hoac009","article-title":"ESHRE guideline: Endometriosis","volume":"2022","author":"Becker","year":"2022","journal-title":"Hum. Reprod. Open"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/S0140-6736(01)06455-8","article-title":"Reproductive consequences of COX-2 inhibition","volume":"358","author":"Norman","year":"2001","journal-title":"Lancet"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1136\/annrheumdis-2014-205383","article-title":"Fertility in women with rheumatoid arthritis: Influence of disease activity and medication","volume":"74","author":"Brouwer","year":"2015","journal-title":"Ann. Rheum. Dis."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1002\/acr.20510","article-title":"Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies","volume":"63","author":"Micu","year":"2011","journal-title":"Arthritis Care Res."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/978-1-4899-0952-7_8","article-title":"Ovulation as a tissue remodelling process. Proteolysis and cumulus expansion","volume":"377","author":"Tsafriri","year":"1995","journal-title":"Adv. Exp. Med. Biol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1093\/rheumatology\/35.5.458","article-title":"Reversible ovulatory failure associated with the development of luteinized unruptured follicles in women with inflammatory arthritis taking non-steroidal anti-inflammatory drugs","volume":"35","author":"Smith","year":"1996","journal-title":"Br. J. Rheumatol."},{"key":"ref_78","first-page":"CD001019","article-title":"Oral contraceptives for pain associated with endometriosis","volume":"5","author":"Brown","year":"2018","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_79","first-page":"CD002122","article-title":"Progestagens and anti-progestagens for pain associated with endometriosis","volume":"2012","author":"Brown","year":"2012","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0010-7824(81)90035-4","article-title":"Pituitary response to LHRH stimulation in women on oral contraceptives: A followup dose response study","volume":"24","author":"Wan","year":"1981","journal-title":"Contraception"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"d6423","DOI":"10.1136\/bmj.d6423","article-title":"Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001\u20132009","volume":"343","author":"Lidegaard","year":"2011","journal-title":"BMJ"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1007\/s40265-018-0928-0","article-title":"Current and Emerging Therapeutics for the Management of Endometriosis","volume":"78","author":"Ferrero","year":"2018","journal-title":"Drugs"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1002\/uog.10114","article-title":"Quantifying effect of combined oral contraceptive pill on functional ovarian reserve as measured by serum anti-Mullerian hormone and small antral follicle count using three-dimensional ultrasound","volume":"39","author":"Deb","year":"2012","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.fertnstert.2012.11.034","article-title":"Antimullerian hormone levels decrease in women using combined contraception independently of administration route","volume":"99","author":"Kallio","year":"2013","journal-title":"Fertil. Steril."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.rbmo.2019.10.004","article-title":"Ovarian reserve markers after discontinuing long-term use of combined oral contraceptives","volume":"40","author":"Landersoe","year":"2020","journal-title":"Reprod. Biomed. Online"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.fertnstert.2014.05.026","article-title":"Antimullerian hormone and antral follicle count are lower in female cancer survivors and healthy women taking hormonal contraception","volume":"102","author":"Johnson","year":"2014","journal-title":"Fertil. Steril."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1093\/humrep\/dev197","article-title":"Ovarian reserve assessment in users of oral contraception seeking fertility advice on their reproductive lifespan","volume":"30","author":"Hvidman","year":"2015","journal-title":"Hum. Reprod."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/13625187.2019.1702158","article-title":"Ovarian reserve markers in women using various hormonal contraceptives","volume":"25","author":"Landersoe","year":"2020","journal-title":"Eur. J. Contracept. Reprod. Health Care"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"515.e1","DOI":"10.1016\/j.ajog.2021.06.052","article-title":"Anti-Mullerian hormone levels among contraceptive users: Evidence from a cross-sectional cohort of 27,125 individuals","volume":"225","author":"Hariton","year":"2021","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1089\/jwh.2019.7733","article-title":"Assessment of Circulating Anti-Mullerian Hormone in Women Using Hormonal Contraception: A Systematic Review","volume":"29","author":"Amer","year":"2020","journal-title":"J. Womens Health"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.contraception.2007.11.005","article-title":"Evaluation of pituitary-ovarian axis suppression with three oral contraceptive regimens","volume":"77","author":"Vandever","year":"2008","journal-title":"Contraception"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/humupd\/8.4.345","article-title":"Residual ovarian activity during oral steroid contraception","volume":"8","author":"Fauser","year":"2002","journal-title":"Hum. Reprod. Update"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1080\/09513590.2020.1756250","article-title":"Ovarian reserve markers and endocrine profile during oral contraception: Is there a link between the degree of ovarian suppression and AMH?","volume":"36","author":"Landersoe","year":"2020","journal-title":"Gynecol. Endocrinol."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1210\/edrv-17-2-121","article-title":"Regulation of ovarian follicular development in primates: Facts and hypotheses","volume":"17","author":"Gougeon","year":"1996","journal-title":"Endocr. Rev."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/17425255.2018.1461840","article-title":"Current understanding on pharmacokinetics, clinical efficacy and safety of progestins for treating pain associated to endometriosis","volume":"14","author":"Barra","year":"2018","journal-title":"Expert Opin. Drug Metab. Toxicol."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1517\/14656566.2014.943734","article-title":"Dienogest in the treatment of endometriosis","volume":"15","author":"Bizzarri","year":"2014","journal-title":"Expert Opin. Pharmacother."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jsbmb.2014.12.008","article-title":"Dienogest, a synthetic progestin, down-regulates expression of CYP19A1 and inflammatory and neuroangiogenesis factors through progesterone receptor isoforms A and B in endometriotic cells","volume":"147","author":"Ichioka","year":"2015","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/humrep\/13.5.1133","article-title":"Development of human primordial follicles to antral stages in SCID\/hpg mice stimulated with follicle stimulating hormone","volume":"13","author":"Oktay","year":"1998","journal-title":"Hum. Reprod."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1002\/med.21802","article-title":"Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review","volume":"41","author":"Hung","year":"2021","journal-title":"Med. Res. Rev."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/j.fertnstert.2006.03.047","article-title":"Antimullerian hormone and pituitary gland activity after prolonged down-regulation with goserelin acetate","volume":"86","author":"Mohamed","year":"2006","journal-title":"Fertil. Steril."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.ejogrb.2015.10.016","article-title":"The impact of GnRH agonists in patients with endometriosis on prolactin and sex hormone levels: A pilot study","volume":"195","author":"Marschalek","year":"2015","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.rbmo.2020.06.020","article-title":"Effect of GnRH agonist before IVF on outcomes in infertile endometriosis patients: A randomized controlled trial","volume":"41","author":"Monzo","year":"2020","journal-title":"Reprod. Biomed. Online"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ijgo.2007.08.021","article-title":"Ovarian suppression treatment prior to in-vitro fertilization and embryo transfer in Chinese women with stage III or IV endometriosis","volume":"100","author":"Ma","year":"2008","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"ref_104","first-page":"CD013240","article-title":"Long-term GnRH agonist therapy before in vitro fertilisation (IVF) for improving fertility outcomes in women with endometriosis","volume":"2019","author":"Georgiou","year":"2019","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1056\/NEJMoa1700089","article-title":"Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist","volume":"377","author":"Taylor","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.fertnstert.2020.02.114","article-title":"Treatment of endometriosis-associated pain with linzagolix, an oral gonadotropin-releasing hormone-antagonist: A randomized clinical trial","volume":"114","author":"Donnez","year":"2020","journal-title":"Fertil. Steril."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1016\/S0140-6736(22)00622-5","article-title":"Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: Two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2)","volume":"399","author":"Giudice","year":"2022","journal-title":"Lancet"},{"key":"ref_108","first-page":"CD004992","article-title":"Excisional surgery versus ablative surgery for ovarian endometriomata","volume":"16","author":"Hart","year":"2008","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1016\/j.fertnstert.2012.08.009","article-title":"Surgical excision of endometriomas and ovarian reserve: A systematic review on serum antimullerian hormone level modifications","volume":"98","author":"Somigliana","year":"2012","journal-title":"Fertil. Steril."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.1210\/jc.2012-1558","article-title":"The impact of excision of ovarian endometrioma on ovarian reserve: A systematic review and meta-analysis","volume":"97","author":"Raffi","year":"2012","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1111\/j.1447-0756.2012.01845.x","article-title":"Histological assessment of impact of ovarian endometrioma and laparoscopic cystectomy on ovarian reserve","volume":"38","author":"Kuroda","year":"2012","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1093\/humrep\/dep043","article-title":"Analysis of risk factors for the removal of normal ovarian tissue during laparoscopic cystectomy for ovarian endometriosis","volume":"24","author":"Matsuzaki","year":"2009","journal-title":"Hum. Reprod."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1016\/j.fertnstert.2011.02.034","article-title":"Histologic analysis of specimens from laparoscopic endometrioma excision performed by different surgeons: Does the surgeon matter?","volume":"95","author":"Muzii","year":"2011","journal-title":"Fertil. Steril."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.fertnstert.2011.04.068","article-title":"Ovarian cystectomy versus laser vaporization in the treatment of ovarian endometriomas: A randomized clinical trial with a five-year follow-up","volume":"96","author":"Carmona","year":"2011","journal-title":"Fertil. Steril."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.rbmo.2015.02.012","article-title":"The impact on ovarian reserve of haemostasis by bipolar coagulation versus suture following surgical stripping of ovarian endometrioma: A meta-analysis","volume":"30","author":"Ding","year":"2015","journal-title":"Reprod. Biomed. Online"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.jmig.2014.12.168","article-title":"Effect of hemostatic method on ovarian reserve following laparoscopic endometrioma excision; comparison of suture, hemostatic sealant, and bipolar dessication. A systematic review and meta-analysis","volume":"22","author":"Ata","year":"2015","journal-title":"J. Minim. Invasive Gynecol."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"3124","DOI":"10.1080\/01443615.2022.2106559","article-title":"Effect of early inflammatory reaction on ovarian reserve after laparoscopic cystectomy for ovarian endometriomas","volume":"42","author":"Shi","year":"2022","journal-title":"J. Obstet. Gynaecol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"806574","DOI":"10.3389\/fphys.2021.806574","article-title":"Endometriosis in the Mouse: Challenges and Progress Toward a \u2018Best Fit\u2019 Murine Model","volume":"12","author":"Burns","year":"2021","journal-title":"Front. Physiol."},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Yotova, I., Hudson, Q.J., Pauler, F.M., Proestling, K., Haslinger, I., Kuessel, L., Perricos, A., Husslein, H., and Wenzl, R. (2021). LINC01133 Inhibits Invasion and Promotes Proliferation in an Endometriosis Epithelial Cell Line. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22168385"},{"key":"ref_120","first-page":"69","article-title":"Primary cell lines: False representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines","volume":"3","author":"Pastor","year":"2010","journal-title":"Int. J. Clin. Exp. Med."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1097\/CM9.0000000000000885","article-title":"Establishment of endometriotic models: The past and future","volume":"133","author":"Gu","year":"2020","journal-title":"Chin. Med. J."},{"key":"ref_122","doi-asserted-by":"crossref","unstructured":"Lin, X., Dai, Y., Tong, X., Xu, W., Huang, Q., Jin, X., Li, C., Zhou, F., Zhou, H., and Lin, X. (2020). Excessive oxidative stress in cumulus granulosa cells induced cell senescence contributes to endometriosis-associated infertility. Redox Biol., 30.","DOI":"10.1016\/j.redox.2020.101431"},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.fertnstert.2014.11.015","article-title":"Oocyte environment: Follicular fluid and cumulus cells are critical for oocyte health","volume":"103","author":"Dumesic","year":"2015","journal-title":"Fertil. Steril."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.fertnstert.2019.07.007","article-title":"Investigating the impact of local inflammation on granulosa cells and follicular development in women with ovarian endometriosis","volume":"112","author":"Li","year":"2019","journal-title":"Fertil. Steril."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1016\/j.fertnstert.2013.07.1985","article-title":"A tumor necrosis factor-\u03b1 inhibitor reduces the embryotoxic effects of endometriotic peritoneal fluid","volume":"100","author":"Chen","year":"2013","journal-title":"Fertil. Steril."},{"key":"ref_126","doi-asserted-by":"crossref","unstructured":"Piromlertamorn, W., Saeng-anan, U., and Vutyavanich, T. (2013). Effects of ovarian endometriotic fluid exposure on fertilization rate of mouse oocytes and subsequent embryo development. Reprod. Biol. Endocrinol., 11.","DOI":"10.1186\/1477-7827-11-4"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1055\/s-0040-1718443","article-title":"Follicular Fluid from Infertile Women with Mild Endometriosis Impairs In Vitro Bovine Embryo Development: Potential Role of Oxidative Stress","volume":"43","author":"Giorgi","year":"2021","journal-title":"Rev. Bras. De Ginecol. E Obs."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1177\/1933719108322430","article-title":"Nonhuman primate models for translational research in endometriosis","volume":"16","author":"Kyama","year":"2009","journal-title":"Reprod. Sci."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1292\/jvms.55.7","article-title":"Endometriosis in cynomolgus monkeys retired from breeding","volume":"55","author":"Ami","year":"1993","journal-title":"J. Vet. Med. Sci."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1093\/humrep\/dey095","article-title":"Spontaneous endometriosis in cynomolgus monkeys as a clinically relevant experimental model","volume":"33","author":"Netsu","year":"2018","journal-title":"Hum. Reprod."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.beem.2018.03.004","article-title":"Animal models of endometriosis: Replicating the aetiology and symptoms of the human disorder","volume":"32","author":"Simitsidellis","year":"2018","journal-title":"Best. Pr. Res. Clin. Endocrinol. Metab."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1620\/tjem.226.95","article-title":"Primate model research for endometriosis","volume":"226","author":"Yamanaka","year":"2012","journal-title":"Tohoku J. Exp. Med."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0002-9378(95)90180-9","article-title":"Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis)","volume":"173","author":"Bambra","year":"1995","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1749-6632.2002.tb02791.x","article-title":"A modified baboon model for endometriosis","volume":"955","author":"Fazleabas","year":"2002","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/humupd\/dml026","article-title":"Animal models in endometriosis research","volume":"12","author":"Grummer","year":"2006","journal-title":"Hum. Reprod. Update"},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1749-6632.2002.tb02792.x","article-title":"Using rats as a research model for the study of endometriosis","volume":"955","year":"2002","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jri.2010.05.001","article-title":"Endometriosis research: Animal models for the study of a complex disease","volume":"86","author":"Barrientos","year":"2010","journal-title":"J. Reprod. Immunol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/nm1173","article-title":"Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer","volume":"11","author":"Dinulescu","year":"2005","journal-title":"Nat. Med."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0015-0282(16)45199-X","article-title":"Surgical induction of endometriosis in the rabbit: Effects on fertility and concentrations of peritoneal fluid prostaglandins","volume":"34","author":"Schenken","year":"1980","journal-title":"Fertil. Steril."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/0002-9378(93)90642-V","article-title":"The presence of luteinized unruptured follicle syndrome and altered folliculogenesis in rats with surgically induced endometriosis","volume":"169","author":"Moon","year":"1993","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1095\/biolreprod60.4.954","article-title":"Effect of pelvic endometrial implants on overall reproductive functions of female rats","volume":"60","author":"Pal","year":"1999","journal-title":"Biol. Reprod."},{"key":"ref_142","doi-asserted-by":"crossref","unstructured":"Elsherbini, M., Koga, K., Maki, E., Kumasawa, K., Satake, E., Taguchi, A., Makabe, T., Takeuchi, A., Izumi, G., and Takamura, M. (2022). Impact of Chronic Exposure to Endometriosis on Perinatal Outcomes: Establishment of a Mouse Model. Biomedicines, 10.","DOI":"10.3390\/biomedicines10102627"},{"key":"ref_143","unstructured":"Bengochea, T.S.O.C., Ricci, A.G., Abramovich, D., Parborell, F., Meresman, G.F., Bara\u00f1ao, R.I., and Bilotas, M.A. (2016). XVIII Jornadas Anuales Multidisciplinarias, De la Sociedad Argentina de Biolog\u00eda."},{"key":"ref_144","first-page":"416","article-title":"Cyclic changes of peritoneal fluid parameters in normal and infertile patients","volume":"69","author":"Syrop","year":"1987","journal-title":"Obstet. Gynecol."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0015-0282(98)00204-0","article-title":"The follicular and endocrine environment in women with endometriosis: Local and systemic cytokine production","volume":"70","author":"Pellicer","year":"1998","journal-title":"Fertil. Steril."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1093\/humrep\/15.6.1250","article-title":"Elevated expression of tumour necrosis factor alpha in cultured granulosa cells from women with endometriosis","volume":"15","author":"Carlberg","year":"2000","journal-title":"Hum. Reprod."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0015-0282(01)01816-7","article-title":"Role of cytokines in endometriosis","volume":"76","author":"Harada","year":"2001","journal-title":"Fertil. Steril."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1023\/A:1009495913119","article-title":"Relationships between concentrations of tumor necrosis factor-alpha and nitric oxide in follicular fluid and oocyte quality","volume":"17","author":"Lee","year":"2000","journal-title":"J. Assist. Reprod. Genet."},{"key":"ref_149","doi-asserted-by":"crossref","unstructured":"Cacciottola, L., Donnez, J., and Dolmans, M.-M. (2021). Can Endometriosis-Related Oxidative Stress Pave the Way for New Treatment Targets?. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22137138"},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.mam.2013.06.001","article-title":"The root of reduced fertility in aged women and possible therapentic options: Current status and future perspects","volume":"38","author":"Qiao","year":"2014","journal-title":"Mol. Asp. Med."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1262\/jrd.2019-091","article-title":"Increased supply from blood vessels promotes the activation of dormant primordial follicles in mouse ovaries","volume":"66","author":"Komatsu","year":"2020","journal-title":"J. Reprod. Dev."},{"key":"ref_152","doi-asserted-by":"crossref","unstructured":"Saito, A., Iwase, A., Nakamura, T., Osuka, S., Murase, T., Kato, N., Ishida, C., Takikawa, S., and Goto, M. (2016). Involvement of mesosalpinx in endometrioma is a possible risk factor for decrease of ovarian reserve after cystectomy: A retrospective cohort study. Reprod. Biol. Endocrinol., 14.","DOI":"10.1186\/s12958-016-0210-9"},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3892\/etm.2020.9242","article-title":"Effect of endometrioma and its surgical excision on fertility (Review)","volume":"20","author":"Jiang","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"ref_154","first-page":"71","article-title":"Manipulation of human ovarian function: Physiological concepts and clinical consequences","volume":"18","author":"Fauser","year":"1997","journal-title":"Endocr. Rev."},{"key":"ref_155","doi-asserted-by":"crossref","unstructured":"Drummond, A.E. (2006). The role of steroids in follicular growth. Reprod. Biol. Endocrinol., 4.","DOI":"10.1186\/1477-7827-4-16"},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1210\/jc.2013-3873","article-title":"Association Between Sex Steroids, Ovarian Reserve, and Vitamin D Levels in Healthy Nonobese Women","volume":"99","author":"Chang","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"ref_157","doi-asserted-by":"crossref","unstructured":"Marquardt, R.M., Kim, T.H., Shin, J.H., and Jeong, J.W. (2019). Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis?. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20153822"},{"key":"ref_158","doi-asserted-by":"crossref","unstructured":"Chantalat, E., Valera, M.C., Vaysse, C., Noirrit, E., Rusidze, M., Weyl, A., Vergriete, K., Buscail, E., Lluel, P., and Fontaine, C. (2020). Estrogen Receptors and Endometriosis. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21082815"},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3390\/endocrines2020014","article-title":"The Effects of Endometriosis on Ovarian Functions","volume":"2","author":"Kitajima","year":"2021","journal-title":"Endocrines"},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/s00441-011-1309-0","article-title":"Cellular and molecular basis for endometriosis-associated infertility","volume":"349","author":"Stilley","year":"2012","journal-title":"Cell Tissue Res."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0002-9378(89)90083-5","article-title":"Effect of ovarian endometriosis on ovulation in rabbits","volume":"160","author":"Kaplan","year":"1989","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/path.4657","article-title":"Models of endometriosis and their utility in studying progression to ovarian clear cell carcinoma","volume":"238","author":"King","year":"2016","journal-title":"J. Pathol."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/bs.vh.2018.01.013","article-title":"The Effect of Steroid Hormones on Ovarian Follicle Development","volume":"107","author":"Chou","year":"2018","journal-title":"Vitam. Horm."},{"key":"ref_164","doi-asserted-by":"crossref","unstructured":"Chauvin, S., Cohen-Tannoudji, J., and Guigon, C.J. (2022). Estradiol Signaling at the Heart of Folliculogenesis: Its Potential Deregulation in Human Ovarian Pathologies. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23010512"},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"3960","DOI":"10.1210\/en.2012-1294","article-title":"Role of Estrogen Receptor Signaling Required for Endometriosis-Like Lesion Establishment in a Mouse Model","volume":"153","author":"Burns","year":"2012","journal-title":"Endocrinology"},{"key":"ref_166","doi-asserted-by":"crossref","unstructured":"Pati\u00f1o-Garc\u00eda, D., Palomino, J., Pom\u00e9s, C., Celle, C., Torres-Estay, V., and Orellana, R. (2023). Estetrol Increases Progesterone Genetic Response without Triggering Common Estrogenic Effects in Endometriotic Cell Lines and Primary Cultures. Biomedicines, 11.","DOI":"10.3390\/biomedicines11041169"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/humupd\/6.1.56","article-title":"Pituitary-ovarian dysfunction and endometriosis","volume":"6","author":"Cahill","year":"2000","journal-title":"Hum. Reprod. Update"},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.fertnstert.2013.12.049","article-title":"Enhanced follicular recruitment and atresia in cortex derived from ovaries with endometriomas","volume":"101","author":"Kitajima","year":"2014","journal-title":"Fertil. Steril."},{"key":"ref_169","doi-asserted-by":"crossref","unstructured":"Maidarti, M., Anderson, R.A., and Telfer, E.E. (2020). Crosstalk between PTEN\/PI3K\/Akt Signalling and DNA Damage in the Oocyte: Implications for Primordial Follicle Activation, Oocyte Quality and Ageing. Cells, 9.","DOI":"10.3390\/cells9010200"},{"key":"ref_170","doi-asserted-by":"crossref","unstructured":"Jagarlamudi, K., Liu, L., Adhikari, D., Reddy, P., Idahl, A., Ottander, U., Lundin, E., and Liu, K. (2009). Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN\/PI3K signaling in oocytes in controlling follicular activation. PLoS ONE, 4.","DOI":"10.1371\/journal.pone.0006186"},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/GCO.0000000000000268","article-title":"Activation of dormant follicles: A new treatment for premature ovarian failure?","volume":"28","author":"Kawamura","year":"2016","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"ref_172","doi-asserted-by":"crossref","unstructured":"De Felici, M., and Klinger, F.G. (2021). PI3K\/PTEN\/AKT Signaling Pathways in Germ Cell Development and Their Involvement in Germ Cell Tumors and Ovarian Dysfunctions. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22189838"},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1126\/science.1193573","article-title":"Granulosa cell ligand NPPC and its receptor NPR2 maintain meiotic arrest in mouse oocytes","volume":"330","author":"Zhang","year":"2010","journal-title":"Science"},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1038\/ncomms2861","article-title":"Constitutively active Foxo3 in oocytes preserves ovarian reserve in mice","volume":"4","author":"Pelosi","year":"2013","journal-title":"Nat. Commun."},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Andrade, G.M., da Silveira, J.C., Perrini, C., Del Collado, M., Gebremedhn, S., Tesfaye, D., Meirelles, F.V., and Perecin, F. (2017). The role of the PI3K-Akt signaling pathway in the developmental competence of bovine oocytes. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0185045"},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1055\/s-0031-1272475","article-title":"Management and prevention of pelvic adhesions","volume":"29","author":"Tulandi","year":"2011","journal-title":"Semin. Reprod. Med."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"1000422","DOI":"10.4172\/2161-0932.1000422","article-title":"Reduction of Postoperative Adhesions after Laparoscopic Surgery for Endometriosis by Using a Novel Anti-Fibrotic Drug Pirfenidone: A Randomized Double Blind Study","volume":"7","author":"Halwagy","year":"2017","journal-title":"Gynecol. Obstet."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1007\/s00423-021-02193-x","article-title":"Adhesion prevention after endometriosis surgery\u2014Results of a randomized, controlled clinical trial with second-look laparoscopy","volume":"406","author":"Kramer","year":"2021","journal-title":"Langenbecks Arch. Surg."},{"key":"ref_179","doi-asserted-by":"crossref","unstructured":"Kramer, B., Andress, J., Neis, F., Hoffmann, S., Brucker, S., Kommoss, S., and Holler, A. (2023). Improvement in Fertility and Pain after Endometriosis Resection and Adhesion Prevention with 4DryField\u00ae PH: Follow-up of a Randomized Controlled Clinical Trial. J. Clin. Med., 12.","DOI":"10.3390\/jcm12103597"},{"key":"ref_180","first-page":"160","article-title":"Clinical experience with the surgicel family of absorbable hemostats (oxidized regenerated cellulose) in neurosurgical applications: A review","volume":"25","author":"Keshavarzi","year":"2013","journal-title":"Wounds"},{"key":"ref_181","doi-asserted-by":"crossref","unstructured":"Wu, Q., Yang, Q., Lin, Y., Wu, L., and Lin, T. (2023). The optimal time for laparoscopic excision of ovarian endometrioma: A prospective randomized controlled trial. Reprod. Biol. Endocrinol., 21.","DOI":"10.1186\/s12958-023-01109-2"},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"D1398","DOI":"10.1093\/nar\/gkab953","article-title":"Therapeutic target database update 2022: Facilitating drug discovery with enriched comparative data of targeted agents","volume":"50","author":"Zhou","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1186\/s40425-019-0706-x","article-title":"Phase I trial of HuMax-IL8 (BMS-986253), an anti-IL-8 monoclonal antibody, in patients with metastatic or unresectable solid tumors","volume":"7","author":"Bilusic","year":"2019","journal-title":"J. Immunother. Cancer"},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.ygyno.2017.08.001","article-title":"A phase I trial of intraperitoneal GEN-1, an IL-12 plasmid formulated with PEG-PEI-cholesterol lipopolymer, administered with pegylated liposomal doxorubicin in patients with recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancers: An NRG Oncology\/Gynecologic Oncology Group study","volume":"147","author":"Thaker","year":"2017","journal-title":"Gynecol. Oncol."},{"key":"ref_185","unstructured":"Petroski, N. (2017). Immunopotentiators in Modern Vaccines, National Library of Medicine."},{"key":"ref_186","unstructured":"(2023, February 01). Mayoclinic Tafenoquine (Oral Route). Available online: https:\/\/www.mayoclinic.org\/drugs-supplements\/tafenoquine-oral-route\/side-effects\/drg-20443911."},{"key":"ref_187","unstructured":"(2023, July 30). Mayoclinic Drugs and Supplements, Sirolimus (Oral Route). Available online: https:\/\/www.mayoclinic.org\/drugs-supplements\/sirolimus-oral-route\/side-effects\/drg-20068199."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/0031-9422(92)80255-D","article-title":"Antioxidative activities of Olea europaea leaves and related phenolic compounds","volume":"31","author":"Guedon","year":"1992","journal-title":"Phytochemistry"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.pain.2013.02.025","article-title":"Efficacy of melatonin in the treatment of endometriosis: A phase II, randomized, double-blind, placebo-controlled trial","volume":"154","author":"Schwertner","year":"2013","journal-title":"Pain"},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1007\/s00404-014-3466-3","article-title":"The effects of different doses of melatonin treatment on endometrial implants in an oophorectomized rat endometriosis model","volume":"291","author":"Cetinkaya","year":"2015","journal-title":"Arch. Gynecol. Obstet."},{"key":"ref_191","doi-asserted-by":"crossref","unstructured":"Li, Y., Hung, S.W., Zhang, R., Man, G.C., Zhang, T., Chung, J.P., Fang, L., and Wang, C.C. (2022). Melatonin in Endometriosis: Mechanistic Understanding and Clinical Insight. Nutrients, 14.","DOI":"10.3390\/nu14194087"},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1038\/214919a0","article-title":"Acute pharmacology of melatonin","volume":"214","author":"Barchas","year":"1967","journal-title":"Nature"},{"key":"ref_193","doi-asserted-by":"crossref","unstructured":"Zhao, X., Wang, D., Wu, Z., Pan, B., Yang, H., Zeng, C., Zhang, M., Liu, G., Han, H., and Zhou, G. (2018). Female Reproductive Performance in the Mouse: Effect of Oral Melatonin. Molecules, 23.","DOI":"10.3390\/molecules23081845"},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1007\/s10815-011-9604-y","article-title":"Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems","volume":"28","author":"Eryilmaz","year":"2011","journal-title":"J. Assist. Reprod. Genet."}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/24\/21\/15967\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:17:39Z","timestamp":1760131059000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/24\/21\/15967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,4]]},"references-count":194,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2023,11]]}},"alternative-id":["ijms242115967"],"URL":"https:\/\/doi.org\/10.3390\/ijms242115967","relation":{},"ISSN":["1422-0067"],"issn-type":[{"value":"1422-0067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,4]]}}}