{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:15:24Z","timestamp":1791555324723,"version":"4.3.4"},"reference-count":149,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research Foundation of Korea","award":["2021R1A6A1A03038785"],"award-info":[{"award-number":["2021R1A6A1A03038785"]}]},{"name":"National Research Foundation of Korea","award":["2021R1F1A1055694"],"award-info":[{"award-number":["2021R1F1A1055694"]}]},{"name":"National Research Foundation of Korea","award":["2021R1C1C1013875"],"award-info":[{"award-number":["2021R1C1C1013875"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Diabetes is one of the most significant causes of death all over the world. This illness, due to abnormal blood glucose levels, leads to impaired wound healing and, as a result, foot ulcers. These ulcers cannot heal quickly in diabetic patients and may finally result in amputation. In recent years, different research has been conducted to heal diabetic foot ulcers: one of them is using cold atmospheric pressure plasma. Nowadays, cold atmospheric pressure plasma is highly regarded in medicine because of its positive effects and lack of side effects. These conditions have caused plasma to be considered a promising technology in medicine and especially diabetic wound healing because studies show that it can heal chronic wounds that are resistant to standard treatments. The positive effects of plasma are due to different reactive species, UV radiation, and electromagnetic fields. This work reviews ongoing cold atmospheric pressure plasma improvements in diabetic wound healing. It shows that plasma can be a promising tool in treating chronic wounds, including ones resulting from diabetes.<\/jats:p>","DOI":"10.3390\/ijms242316657","type":"journal-article","created":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T06:06:23Z","timestamp":1700719583000},"page":"16657","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing\u2014Mechanism and Clinical Significance"],"prefix":"10.3390","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9758-8602","authenticated-orcid":false,"given":"Azadeh","family":"Barjasteh","sequence":"first","affiliation":[{"name":"Department of Physics, Lorestan University, Khorramabad 68151-44316, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8671-6779","authenticated-orcid":false,"given":"Neha","family":"Kaushik","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, College of Engineering, The University of Suwon, Hwaseong 18323, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5385-1878","authenticated-orcid":false,"given":"Eun Ha","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Electrical and Biological Physics\/Plasma, Bioscience Research Center, Kwangwoon University, Seoul 01897, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4965-5046","authenticated-orcid":false,"given":"Nagendra Kumar","family":"Kaushik","sequence":"additional","affiliation":[{"name":"Department of Electrical and Biological Physics\/Plasma, Bioscience Research Center, Kwangwoon University, Seoul 01897, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1111\/iwj.13341","article-title":"The efficacy and safety of cold atmospheric plasma as a novel therapy for diabetic wound in vitro and in vivo","volume":"17","author":"He","year":"2020","journal-title":"Int. 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