{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:58:14Z","timestamp":1791914294430,"version":"4.3.4"},"reference-count":123,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T00:00:00Z","timestamp":1701129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Pyogenic granuloma (PG) is a benign vascular lesion found predominantly in the oral cavity. Characterized by rapid growth and propensity to bleed, PG presents diagnostic challenges due to its similarity and alarming proliferation. This narrative review synthesizes current knowledge on the epidemiology, etiopathogenesis, clinical manifestations, and management of oral PG, with emphasis on recent advances in diagnostic and therapeutic approaches. The epidemiology of the injury is meticulously analyzed, revealing a higher incidence in women and a wide range of ages of onset. It delves into the etiopathogenesis, highlighting the uncertainty surrounding the exact causal factors, although historical attributions suggest an infectious origin. It exhaustively analyzes the clinical and histopathological aspects of oral PG, offering information on its various presentations and the importance of an accurate diagnosis to guide effective treatment. It details treatment strategies, emphasizing the personalized approach based on individual patient characteristics. This comprehensive review consolidates current knowledge on oral PG, highlighting the need for further research to clarify its pathogenesis and optimize treatment protocols.<\/jats:p>","DOI":"10.3390\/ijms242316885","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T11:43:16Z","timestamp":1701171796000},"page":"16885","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Oral Pyogenic Granuloma: A Narrative Review"],"prefix":"10.3390","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0569-1387","authenticated-orcid":false,"given":"Sarah Monserrat","family":"Lomeli Martinez","sequence":"first","affiliation":[{"name":"Department of Medical and Life Sciences, University of Guadalajara (CUCi\u00e9nega-UdeG), 1115 Ave. Universidad, Ocotl\u00e1n 47810, Jalisco, Mexico"},{"name":"Master of Public Health, Department of Wellbeing and Sustainable Development, University of Guadalajara (CUNorte-UdeG), 23 Federal Highway, Km. 191, Colotl\u00e1n 46200, Jalisco, Mexico"},{"name":"Periodontics Program, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico"},{"name":"Prostodontics Program, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia Guadalupe","family":"Carrillo Contreras","sequence":"additional","affiliation":[{"name":"Periodontics Program, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3336-5159","authenticated-orcid":false,"given":"Juan Ram\u00f3n","family":"G\u00f3mez Sandoval","sequence":"additional","affiliation":[{"name":"Periodontics Program, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico"},{"name":"Research Institute of Dentistry, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Sergio","family":"Zepeda Nu\u00f1o","sequence":"additional","affiliation":[{"name":"Microbiology and Pathology Department, Pathology Laboratory, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Gomez Mireles","sequence":"additional","affiliation":[{"name":"Periodontics Program, Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Jos\u00e9","family":"Varela Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Medical and Life Sciences, University of Guadalajara (CUCi\u00e9nega-UdeG), 1115 Ave. Universidad, Ocotl\u00e1n 47810, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Esther","family":"Mercado-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Antiguo Hospital Civil de Guadalajara \u201cFray Antonio Alcalde\u201d, 777 Coronel Calder\u00f3n, Guadalajara 44200, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0851-348X","authenticated-orcid":false,"given":"Rub\u00e9n Alberto","family":"Bayardo Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Integrated Dentistry Clinics, University of Guadalajara (CUCS-UdeG), 950 Sierra Mojada, Guadalajara 44340, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1645-8705","authenticated-orcid":false,"given":"Adri\u00e1n Fernando","family":"Guti\u00e9rrez-Maldonado","sequence":"additional","affiliation":[{"name":"Department of Medical and Life Sciences, University of Guadalajara (CUCi\u00e9nega-UdeG), 1115 Ave. Universidad, Ocotl\u00e1n 47810, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,28]]},"reference":[{"key":"ref_1","unstructured":"Sarwal, P., and Lapumnuaypol, K. 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