{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:21:16Z","timestamp":1790090476085,"version":"4.0.1"},"reference-count":35,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T00:00:00Z","timestamp":1706832000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Saint Petersburg State University","award":["1021050501070-0-1.4.3"],"award-info":[{"award-number":["1021050501070-0-1.4.3"]}]},{"name":"Saint Petersburg State University","award":["0097-2022-0006"],"award-info":[{"award-number":["0097-2022-0006"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>The experimental study of the DNA interaction with three cadmium coordination compounds [Cd(phen)3](CH3CO2)2, [Cd(phen)2(H2O)2](CH3CO2)2, and [Cd2(phen)4(H2O)2](CH3CO2)4 was carried out using spectrophotometry, viscosity, and dynamic light scattering methods. The role of the solution ionic strength (concentration of NaCl) was analyzed. All compounds can penetrate (fully or partly) to the major or minor DNA grooves. It was shown that, in addition to the important role of electrostatic interactions in the formation of the complex, intercalation of the 1,10-phenanthroline ligand occurs for compounds [Cd(phen)2(H2O)2](CH3CO2)2 and [Cd2(phen)4(H2O)2](CH3CO2)4. Compound [Cd(phen)3](CH3CO2)2 binds to DNA externally. The coordination bond between cadmium and DNA was formed in DNA complexes with [Cd2(phen)4(H2O)2](CH3CO2)4. Preliminary computer modeling of the DNA interaction with the compounds used was performed.<\/jats:p>","DOI":"10.3390\/ijms25031820","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T09:24:08Z","timestamp":1706865848000},"page":"1820","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["DNA Interaction with Coordination Compounds of Cd(II)containing 1,10-Phenanthroline"],"prefix":"10.3390","volume":"25","author":[{"given":"Nina","family":"Kasyanenko","sequence":"first","affiliation":[{"name":"Faculty of Physics, Saint Petersburg State University, 199034 Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugeny","family":"Belyi","sequence":"additional","affiliation":[{"name":"Faculty of Physics, Saint Petersburg State University, 199034 Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3926-9846","authenticated-orcid":false,"given":"Irina","family":"Silanteva","sequence":"additional","affiliation":[{"name":"Faculty of Physics, Saint Petersburg State University, 199034 Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Demidov","sequence":"additional","affiliation":[{"name":"I.V. Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences, 194021 Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3577-1978","authenticated-orcid":false,"given":"Andrei","family":"Komolkin","sequence":"additional","affiliation":[{"name":"Faculty of Physics, Saint Petersburg State University, 199034 Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/205698a0","article-title":"Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode","volume":"205","author":"Rosenberg","year":"1965","journal-title":"Nature"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1595\/003214071X1524251","article-title":"Some Biological effects of platinum compounds","volume":"15","author":"Rosenberg","year":"1971","journal-title":"Platin. 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