{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T14:37:14Z","timestamp":1769092634814,"version":"3.49.0"},"reference-count":49,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>The management of hyperparathyroidism (intact parathyroid hormone (iPTH) serum levels &gt; 585 pg\/mL), frequently focuses on the appropriate control of mineral and bone markers, with the decrease in serum and dietary phosphorus as two of the targets. We aimed to investigate the association between iPTH, serum phosphorus levels and dietary intake. This was a cross-sectional, multicenter, observational study with 561 patients on hemodialysis treatment. Clinical parameters, body composition and dietary intake were assessed. For the analysis, patients were divided into three groups: (a) iPTH &lt; 130, (b) iPTH between 130 and 585 and (c) iPTH &gt; 585 pg\/mL. The association between PTH, serum phosphorus and dietary intake was analyzed using linear regression models. In the whole sample, 23.2% of patients presented an iPTH &gt; 585 pg\/mL. Patients with higher iPTH levels were those with longer HD vintage and lower ages, higher serum phosphorus, serum calcium, Ca\/P product, albumin and caffeine intake, and a lower dietary intake of phosphorus, fiber, riboflavin and folate. Higher serum phosphorus predicted higher iPTH levels, even in the adjusted model. However, lower dietary phosphorus and fiber intake were predictors of higher iPTH levels, including in the adjusted model. Our results bring new data to the relationship between dietary intake and iPTH values. Despite higher serum phosphorus being observed in patients with HPTH, an opposite association was noted regarding dietary phosphate and fiber.<\/jats:p>","DOI":"10.3390\/ijms25042006","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T03:47:09Z","timestamp":1707277629000},"page":"2006","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients: Is There a Novel Relationship?"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3333-4694","authenticated-orcid":false,"given":"Cristina","family":"Garagarza","sequence":"first","affiliation":[{"name":"Nutrition Department, Nephrocare, 1750 Lisboa, Portugal"},{"name":"Laborat\u00f3rio de Nutri\u00e7\u00e3o, Faculdade de Medicina, Universidade de Lisboa, 1649 Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Valente","sequence":"additional","affiliation":[{"name":"Nutrition Department, Nephrocare, 1750 Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e1tia","family":"Queir\u00f3s","sequence":"additional","affiliation":[{"name":"Nutrition Department, Nephrocare, 1750 Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5934-9200","authenticated-orcid":false,"given":"In\u00eas Pastor","family":"Neto","sequence":"additional","affiliation":[{"name":"Nutrition Department, Nephrocare, 1750 Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Sebasti\u00e3o","sequence":"additional","affiliation":[{"name":"Nutrition Department, Nephrocare, 1750 Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Gomes","sequence":"additional","affiliation":[{"name":"Nutrition Department, Nephrocare, 1750 Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An\u00edbal","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Nefrologia, Hospital de Curry Cabral\u2014Centro Hospitalar Universit\u00e1rio de Lisboa Central, 1069 Lisboa, Portugal"},{"name":"NOVA Medical School, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Nova de Lisboa Centro Cl\u00ednico Acad\u00e9mico de Lisboa, 1169 Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Update Work Group (2017). 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