{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:04:29Z","timestamp":1787069069652,"version":"build-2736575974"},"reference-count":305,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union \u2013 Next Generation EU, MISSION 4, COMPONENT 2, \u201cFrom research to business\u201d, INVESTMENT 1.4, \u201cStrengthening research structures and creation of &quot; national R&amp;D champions&quot;","award":["CN00000041"],"award-info":[{"award-number":["CN00000041"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>This review focuses on the latest advancements in magnetic hydroxyapatite (mHA) nanoparticles and their potential applications in nanomedicine and regenerative medicine. mHA nanoparticles have gained significant interest over the last few years for their great potential, offering advanced multi-therapeutic strategies because of their biocompatibility, bioactivity, and unique physicochemical features, enabling on-demand activation and control. The most relevant synthetic methods to obtain magnetic apatite-based materials, either in the form of iron-doped HA nanoparticles showing intrinsic magnetic properties or composite\/hybrid compounds between HA and superparamagnetic metal oxide nanoparticles, are described as highlighting structure\u2013property correlations. Following this, this review discusses the application of various magnetic hydroxyapatite nanomaterials in bone regeneration and nanomedicine. Finally, novel perspectives are investigated with respect to the ability of mHA nanoparticles to improve nanocarriers with homogeneous structures to promote multifunctional biological applications, such as cell stimulation and instruction, antimicrobial activity, and drug release with on-demand triggering.<\/jats:p>","DOI":"10.3390\/ijms25052809","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T02:59:39Z","timestamp":1709175579000},"page":"2809","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Magnetic Hydroxyapatite Nanoparticles in Regenerative Medicine and Nanomedicine"],"prefix":"10.3390","volume":"25","author":[{"given":"Hina","family":"Inam","sequence":"first","affiliation":[{"name":"Institute of Science, Technology and Sustainability for Ceramics (ISSMC), National Research Council of Italy (CNR), 48018 Faenza, Italy"},{"name":"Department of Material Science and Technology, University of Parma, 43121 Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1526-7915","authenticated-orcid":false,"given":"Simone","family":"Sprio","sequence":"additional","affiliation":[{"name":"Institute of Science, Technology and Sustainability for Ceramics (ISSMC), National Research Council of Italy (CNR), 48018 Faenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Tavoni","sequence":"additional","affiliation":[{"name":"Institute of Science, Technology and Sustainability for Ceramics (ISSMC), National Research Council of Italy (CNR), 48018 Faenza, Italy"},{"name":"Department of Material Science and Technology, University of Parma, 43121 Parma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahid","family":"Abbas","sequence":"additional","affiliation":[{"name":"Institute of Science, Technology and Sustainability for Ceramics (ISSMC), National Research Council of Italy (CNR), 48018 Faenza, Italy"},{"name":"Department of Chemistry \u201cGiacomo Ciamician\u201d, University of Bologna, 40126 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Pupilli","sequence":"additional","affiliation":[{"name":"Institute of Science, Technology and Sustainability for Ceramics (ISSMC), National Research Council of Italy (CNR), 48018 Faenza, Italy"},{"name":"Department of Chemical Sciences, University of Padova, 35122 Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Tampieri","sequence":"additional","affiliation":[{"name":"Institute of Science, Technology and Sustainability for Ceramics (ISSMC), National Research Council of Italy (CNR), 48018 Faenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Tran, H.-V., Ngo, N.M., Medhi, R., Srinoi, P., Liu, T., Rittikulsittichai, S., and Lee, T.R. (2022). Multifunctional iron oxide magnetic nanoparticles for biomedical applications: A review. Materials, 15.","DOI":"10.3390\/ma15020503"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Mittal, A., Roy, I., and Gandhi, S. (2022). Magnetic nanoparticles: An overview for biomedical applications. Magnetochemistry, 8.","DOI":"10.3390\/magnetochemistry8090107"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"103899","DOI":"10.1016\/j.jddst.2022.103899","article-title":"Magnetic nanoparticles\u2014A new era in nanotechnology","volume":"77","author":"Chavan","year":"2022","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Schneider, M.G.M., Mart\u00edn, M.J., Otarola, J., Vakarelska, E., Simeonov, V., Lassalle, V., and Nedyalkova, M. (2022). Biomedical applications of iron oxide nanoparticles: Current insights progress and perspectives. Pharmaceutics, 14.","DOI":"10.3390\/pharmaceutics14010204"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"100163","DOI":"10.1016\/j.apsadv.2021.100163","article-title":"Magnetic nanoparticles in biomedical applications: A review","volume":"6","author":"Miyazaki","year":"2021","journal-title":"Appl. Surf. Sci. Adv."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1039\/D0NA00828A","article-title":"Hybrid magnetic nanoparticles as efficient nanoheaters in biomedical applications","volume":"3","author":"Lavorato","year":"2021","journal-title":"Nanoscale Adv."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1002\/nano.202000162","article-title":"Recent progress of magnetic nanoparticles in biomedical applications: A review","volume":"2","author":"Anik","year":"2021","journal-title":"Nano Sel."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"8760","DOI":"10.1039\/c0jm00994f","article-title":"Magnetic nanoparticles: Biomedical applications and challenges","volume":"20","author":"Tran","year":"2010","journal-title":"J. Mater. Chem."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"19632","DOI":"10.1016\/j.ceramint.2021.03.301","article-title":"Greener synthesis and medical applications of metal oxide nanoparticles","volume":"47","author":"Marouzi","year":"2021","journal-title":"Ceram. Int."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"100070","DOI":"10.1016\/j.onano.2022.100070","article-title":"The purview of doped nanoparticles: Insights into their biomedical applications","volume":"8","author":"Shenoy","year":"2022","journal-title":"OpenNano"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"9770212","DOI":"10.1155\/2023\/9770212","article-title":"Green synthesis of cobalt ferrite nanoparticles: An emerging material for environmental and biomedical applications","volume":"2023","author":"Tamboli","year":"2023","journal-title":"J. Nanomater."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"121711","DOI":"10.1016\/j.ijpharm.2022.121711","article-title":"Magnetic mesoporous silica nanoparticles as a theranostic approach for breast cancer: Loading and release of the poorly soluble drug exemestane","volume":"619","author":"Laranjeira","year":"2022","journal-title":"Int. J. Pharm."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"872","DOI":"10.3390\/chemistry4030063","article-title":"Magnetic Nanoparticles: Current Advances in Nanomedicine, Drug Delivery and MRI","volume":"4","author":"Comanescu","year":"2022","journal-title":"Chemistry"},{"key":"ref_14","first-page":"276","article-title":"Iron oxide based magnetic nanomaterials for biomedical applications","volume":"66","author":"Fopase","year":"2020","journal-title":"Magnetochem. Mater. Appl."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"4446","DOI":"10.1021\/acs.inorgchem.6b03143","article-title":"Fe-Doping-Induced Magnetism in Nano-Hydroxyapatites","volume":"56","author":"Iannotti","year":"2017","journal-title":"Inorg. Chem."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Panseri, S., Cunha, C., D\u2019Alessandro, T., Sandri, M., Giavaresi, G., Marcacci, M., Hung, C.T., and Tampieri, A. (2012). Intrinsically superparamagnetic Fe-hydroxyapatite nanoparticles positively influence osteoblast-like cell behaviour. J. Nanobiotechnol., 10.","DOI":"10.1186\/1477-3155-10-32"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.7150\/thno.11544","article-title":"Magnetic nanoparticles in cancer theranostics","volume":"5","author":"Gobbo","year":"2015","journal-title":"Theranostics"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Shabatina, T.I., Vernaya, O.I., Shabatin, V.P., and Melnikov, M.Y. (2020). Magnetic nanoparticles for biomedical purposes: Modern trends and prospects. Magnetochemistry, 6.","DOI":"10.3390\/magnetochemistry6030030"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e1901058","DOI":"10.1002\/adhm.201901058","article-title":"Magnetic nanoparticles in cancer therapy and diagnosis","volume":"9","author":"Farzin","year":"2020","journal-title":"Adv. Healthc. Mater."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Dasari, A., Xue, J., and Deb, S. (2022). Magnetic Nanoparticles in Bone Tissue Engineering. Nanomaterials, 12.","DOI":"10.3390\/nano12050757"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1016\/j.biotechadv.2015.02.003","article-title":"Tailored functionalization of iron oxide nanoparticles for MRI, drug delivery, magnetic separation and immobilization of biosubstances","volume":"33","author":"Hola","year":"2015","journal-title":"Biotechnol. Adv."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.2147\/IJN.S110542","article-title":"Remote magnetic targeting of iron oxide nanoparticles for cardiovascular diagnosis and therapeutic drug delivery: Where are we now?","volume":"11","author":"Yilmaz","year":"2016","journal-title":"Int. J. Nanomed."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.addr.2009.11.002","article-title":"Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging","volume":"62","author":"Veiseh","year":"2010","journal-title":"Adv. Drug Deliv. Rev."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Alshahrani, A.A., Alorabi, A.Q., Hassan, M.S., Amna, T., and Azizi, M. (2022). Chitosan-Functionalized Hydroxyapatite-Cerium Oxide Heterostructure: An Efficient Adsorbent for Dyes Removal and Antimicrobial Agent. Nanomaterials, 12.","DOI":"10.3390\/nano12152713"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1007\/s00396-014-3357-y","article-title":"Magnetic polymer nanocomposites for environmental and biomedical applications","volume":"292","author":"Kalia","year":"2014","journal-title":"Colloid Polym. Sci."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"023501","DOI":"10.1088\/1468-6996\/16\/2\/023501","article-title":"Recent progress on magnetic iron oxide nanoparticles: Synthesis, surface functional strategies and biomedical applications","volume":"16","author":"Wu","year":"2015","journal-title":"Sci. Technol. Adv. Mater."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.partic.2016.06.001","article-title":"Magnetic nanoparticles for environmental and biomedical applications: A review","volume":"30","author":"Mohammed","year":"2017","journal-title":"Particuology"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"110388","DOI":"10.1016\/j.eurpolymj.2021.110388","article-title":"Advanced polymer-based composites and structures for biomedical applications","volume":"149","author":"Guo","year":"2021","journal-title":"Eur. Polym. J."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Govindan, B., Sabri, M.A., Hai, A., Banat, F., and Abu Haija, M. (2023). A Review of Advanced Multifunctional Magnetic Nanostructures for Cancer Diagnosis and Therapy Integrated into an Artificial Intelligence Approach. Pharmaceutics, 15.","DOI":"10.3390\/pharmaceutics15030868"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.trac.2014.06.016","article-title":"Sensors and biosensors based on magnetic nanoparticles","volume":"62","year":"2014","journal-title":"TrAC Trends Anal. Chem."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"10152","DOI":"10.1021\/ie3024438","article-title":"Preparation of Fe3O4@C@ layered double hydroxide composite for magnetic separation of uranium","volume":"52","author":"Zhang","year":"2013","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s10311-020-01149-9","article-title":"Magnetic materials and magnetic separation of dyes from aqueous solutions: A review","volume":"19","author":"Nithya","year":"2021","journal-title":"Environ. Chem. Lett."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"225101","DOI":"10.1088\/0957-4484\/22\/22\/225101","article-title":"Magnetite\/CdTe magnetic\u2013fluorescent composite nanosystem for magnetic separation and bio-imaging","volume":"22","author":"Kale","year":"2011","journal-title":"Nanotechnology"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.desal.2010.08.004","article-title":"Removal of methylene blue from aqueous solution by montmorillonite\/CoFe2O4 composite with magnetic separation performance","volume":"266","author":"Ai","year":"2011","journal-title":"Desalination"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1080\/01496395.2018.1446986","article-title":"Influence of Fe3O4 nanoparticles decoration on dye adsorption and magnetic separation properties of Fe3O4\/rGO nanocomposites","volume":"53","author":"Minitha","year":"2018","journal-title":"Sep. Sci. Technol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s10853-015-9324-2","article-title":"Magnetic nanoparticles: Material engineering and emerging applications in lithography and biomedicine","volume":"51","author":"Bao","year":"2015","journal-title":"J. Mater. Sci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1002\/jbm.a.35654","article-title":"Current investigations into magnetic nanoparticles for biomedical applications","volume":"104","author":"Li","year":"2016","journal-title":"J. Biomed. Mater. Res. Part A"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s13204-013-0216-y","article-title":"Magnetic nanoparticle drug delivery systems for targeting tumor","volume":"4","author":"Mody","year":"2013","journal-title":"Appl. Nanosci."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Nordin, A.H., Ahmad, Z., Husna, S.M.N., Ilyas, R.A., Azemi, A.K., Ismail, N., Nordin, M.L., Ngadi, N., Siti, N.H., and Nabgan, W. (2023). The State of the Art of Natural Polymer Functionalized Fe3O4 Magnetic Nanoparticle Composites for Drug Delivery Applications: A Review. Gels, 9.","DOI":"10.3390\/gels9020121"},{"key":"ref_40","unstructured":"Rana, G., Dhiman, P., and Sharma, A. (2023). Magnetic Nanoferrites and Their Composites, Elsevier."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"4284","DOI":"10.1021\/acsanm.1c00852","article-title":"magnetic nanoparticles: From synthesis to theranostic applications","volume":"4","author":"Khizar","year":"2021","journal-title":"ACS Appl. Nano Mater."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1021\/acsabm.9b00949","article-title":"Facile strategy to synthesize magnetic upconversion nanoscale metal\u2013organic framework composites for theranostics application","volume":"3","author":"Mukherjee","year":"2019","journal-title":"ACS Appl. Bio Mater."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Kucharczyk, K., Rybka, J.D., Hilgendorff, M., Krupinski, M., Slachcinski, M., Mackiewicz, A., Giersig, M., and Dams-Kozlowska, H. (2019). Composite spheres made of bioengineered spider silk and iron oxide nanoparticles for theranostics applications. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0219790"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"103179","DOI":"10.1016\/j.jece.2019.103179","article-title":"Recent advances in copper ferrite nanoparticles and nanocomposites synthesis, magnetic properties and application in water treatment: Review","volume":"7","author":"Masunga","year":"2019","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.apsusc.2018.06.028","article-title":"Hybrid ZnO: Ag core-shell nanoparticles for wastewater treatment: Growth mechanism and plasmonically enhanced photocatalytic activity","volume":"456","author":"Jadhav","year":"2018","journal-title":"Appl. Surf. Sci."},{"key":"ref_46","unstructured":"Khazeni, N. (2013). Synthesis and Characterization of Zirconium Tungstate-Zirconia Core-Shell Composite Particles. [Master\u2019s Thesis, Middle East Technical University]."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1400010","DOI":"10.1002\/advs.201400010","article-title":"Nanoparticle\u2013hydrogel composites: Concept, design, and applications of these promising, multi-functional materials","volume":"2","author":"Thoniyot","year":"2015","journal-title":"Adv. Sci."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"4012","DOI":"10.1016\/j.biomaterials.2008.07.004","article-title":"Magnetic nanoparticles with dual functional properties: Drug delivery and magnetic resonance imaging","volume":"29","author":"Jain","year":"2008","journal-title":"Biomaterials"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1002\/ejic.202000012","article-title":"Fe3O4@MOF magnetic nanocomposites: Synthesis and applications","volume":"2020","author":"Safarifard","year":"2020","journal-title":"Eur. J. Inorg. Chem."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/ceat.201600631","article-title":"Microwave-assisted synthesis of magnetic hydroxyapatite for removal of heavy metals from groundwater","volume":"41","author":"Elkady","year":"2017","journal-title":"Chem. Eng. Technol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/B978-0-12-415769-9.00009-1","article-title":"Application of inorganic nanoparticles for diagnosis based on MRI","volume":"4","year":"2012","journal-title":"Front. Nanosci."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"065602","DOI":"10.1088\/0957-4484\/19\/6\/065602","article-title":"Room temperature synthesis of rod-like FeC2O4\u00b72H2O and its transition to maghemite, magnetite and hematite nanorods through controlled thermal decomposition","volume":"19","author":"Zhou","year":"2008","journal-title":"Nanotechnology"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jmmm.2014.05.015","article-title":"Progress in electrochemical synthesis of magnetic iron oxide nanoparticles","volume":"368","author":"Ramimoghadam","year":"2014","journal-title":"J. Magn. Magn. Mater."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1021\/cr068445e","article-title":"Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications","volume":"108","author":"Laurent","year":"2008","journal-title":"Chem. Rev."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"41305","DOI":"10.1039\/D0RA06683D","article-title":"Activatable superparamagnetic iron oxide nanoparticles scavenge reactive oxygen species in macrophages and endothelial cells","volume":"10","author":"Nwasike","year":"2020","journal-title":"RSC Adv."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"e2001588","DOI":"10.1002\/smll.202001588","article-title":"New insights into biocompatible iron oxide nanoparticles: A potential booster of gene delivery to stem cells","volume":"16","author":"Zhang","year":"2020","journal-title":"Small"},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Wang, N., Xie, Y., Xi, Z., Mi, Z., Deng, R., Liu, X., Kang, R., and Liu, X. (2022). Hope for bone regeneration: The versatility of iron oxide nanoparticles. Front. Bioeng. Biotechnol., 10.","DOI":"10.3389\/fbioe.2022.937803"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Xia, Y., Zhao, Y., Zhang, F., Chen, B., Hu, X., Weir, M.D., Schneider, A., Jia, L., Gu, N., and Xu, H.H. (2019). Iron oxide nanoparticles in liquid or powder form enhanced osteogenesis via stem cells on injectable calcium phosphate scaffold. Nanomed. Nanotechnol. Biol. Med., 21.","DOI":"10.1016\/j.nano.2019.102069"},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Liao, W., Lu, J., Wang, Q., Yan, S., Li, Y., Zhang, Y., Wang, P., Jiang, Q., and Gu, N. (2022). Osteogenesis of iron oxide nanoparticles-labeled human precartilaginous stem cells in interpenetrating network printable hydrogel. Front. Bioeng. Biotechnol., 10.","DOI":"10.3389\/fbioe.2022.872149"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"7850","DOI":"10.1038\/s41598-017-08092-w","article-title":"Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging","volume":"7","author":"Hachani","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"7831","DOI":"10.1039\/C5TB00931F","article-title":"Synthesis and design of biologically inspired biocompatible iron oxide nanoparticles for biomedical applications","volume":"3","author":"Demirer","year":"2015","journal-title":"J. Mater. Chem. B"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3390\/jnt1010008","article-title":"Use of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) via Multiple Imaging Modalities and Modifications to Reduce Cytotoxicity: An Educational Review","volume":"1","author":"Nelson","year":"2020","journal-title":"J. Nanotheranostics"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.2147\/IJN.S26355","article-title":"Subtle cytotoxicity and genotoxicity differences in superparamagnetic iron oxide nanoparticles coated with various functional groups","volume":"6","author":"Han","year":"2011","journal-title":"Int. J. Nanomed."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"110314","DOI":"10.1016\/j.msec.2019.110314","article-title":"Spinel ferrite nanoparticles and nanocomposites for biomedical applications and their toxicity","volume":"107","author":"Kefeni","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ccr.2015.01.001","article-title":"Silica-decorated magnetic nanocomposites for catalytic applications","volume":"288","author":"Gawande","year":"2015","journal-title":"Coord. Chem. Rev."},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Mari\u00f1o, M.A., Fulaz, S., and Tasic, L. (2021). Magnetic nanomaterials as biocatalyst carriers for biomass processing: Immobilization strategies, reusability, and applications. Magnetochemistry, 7.","DOI":"10.3390\/magnetochemistry7100133"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"102696","DOI":"10.1016\/j.jwpe.2022.102696","article-title":"Magnetic-MXene-based nanocomposites for water and wastewater treatment: A review","volume":"47","author":"Mansoorianfar","year":"2022","journal-title":"J. Water Process. Eng."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.molliq.2018.10.161","article-title":"One-step synthesis of hydrophilic functionalized and cytocompatible superparamagnetic iron oxide nanoparticles (SPIONs) based aqueous ferrofluids for biomedical applications","volume":"274","author":"Kandasamy","year":"2018","journal-title":"J. Mol. Liq."},{"key":"ref_69","first-page":"1435","article-title":"SPIONs and magnetic hybrid materials: Synthesis, toxicology and biomedical applications","volume":"8","author":"Friedrich","year":"2021","journal-title":"Phys. Sci. Rev."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1039\/C4BM00119B","article-title":"Multifunctional nanoprobes based on upconverting lanthanide doped CaF2: Towards biocompatible materials for biomedical imaging","volume":"2","author":"Cantarelli","year":"2014","journal-title":"Biomater. Sci."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"7176","DOI":"10.1039\/C4TB00925H","article-title":"An intrinsically magnetic biomaterial with tunable magnetic properties","volume":"2","author":"Zilm","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.matpr.2020.11.1023","article-title":"Sol gel deposited hydroxyapatite-based coating technique on porous titanium niobium for biomedical applications: A mini review","volume":"41","author":"Mohammad","year":"2021","journal-title":"Mater. Today Proc."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"225","DOI":"10.4236\/aces.2018.84016","article-title":"Hydroxyapatite: Preparation, properties and its biomedical applications","volume":"8","author":"Pokhrel","year":"2018","journal-title":"Adv. Chem. Eng. Sci."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.cis.2017.04.007","article-title":"Synthesis of hydroxyapatite for biomedical applications","volume":"249","author":"Chibowski","year":"2017","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1039\/D0TB02407D","article-title":"A review on hydroxyapatite coatings for the biomedical applications: Experimental and theoretical perspectives","volume":"9","author":"Awasthi","year":"2020","journal-title":"J. Mater. Chem. B"},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Sobczak-Kupiec, A., Drabczyk, A., Florkiewicz, W., G\u0142\u0105b, M., Kud\u0142acik-Kramarczyk, S., S\u0142ota, D., Tomala, A., and Tyliszczak, B. (2021). Review of the applications of biomedical compositions containing hydroxyapatite and collagen modified by bioactive components. Materials, 14.","DOI":"10.3390\/ma14092096"},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Ielo, I., Calabrese, G., De Luca, G., and Conoci, S. (2022). Recent advances in hydroxyapatite-based biocomposites for bone tissue regeneration in orthopedics. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23179721"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"7442","DOI":"10.1039\/C6RA26124H","article-title":"Recent advances in the synthesis, functionalization and biomedical applications of hydroxyapatite: A review","volume":"7","author":"Haider","year":"2017","journal-title":"RSC Adv."},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"Shi, H., Zhou, Z., Li, W., Fan, Y., Li, Z., and Wei, J. (2021). Hydroxyapatite based materials for bone tissue engineering: A brief and comprehensive introduction. Crystals, 11.","DOI":"10.3390\/cryst11020149"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"6477","DOI":"10.2147\/IJN.S298936","article-title":"Nanomaterials-upconverted hydroxyapatite for bone tissue engineering and a platform for drug delivery","volume":"16","author":"Halim","year":"2021","journal-title":"Int. J. Nanomed."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"108790","DOI":"10.1016\/j.compositesb.2021.108790","article-title":"Recent advances in biomedical engineering of nano-hydroxyapatite including dentistry, cancer treatment and bone repair","volume":"215","author":"Du","year":"2021","journal-title":"Compos. Part B Eng."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.ijbiomac.2018.06.200","article-title":"Injectable polysaccharide hydrogel embedded with hydroxyapatite and calcium carbonate for drug delivery and bone tissue engineering","volume":"118","author":"Ren","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1016\/j.actbio.2011.03.019","article-title":"Nanoscale hydroxyapatite particles for bone tissue engineering","volume":"7","author":"Zhou","year":"2011","journal-title":"Acta Biomater."},{"key":"ref_84","doi-asserted-by":"crossref","unstructured":"Said, H.A., Mabroum, H., Lahcini, M., Oudadesse, H., Barroug, A., Ben Youcef, H., and Noukrati, H. (2023). Manufacturing methods, properties, and potential applications in bone tissue regeneration of hydroxyapatite-chitosan biocomposites: A review. Int. J. Biol. Macromol., 243.","DOI":"10.1016\/j.ijbiomac.2023.125150"},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Mo, X., Zhang, D., Liu, K., Zhao, X., Li, X., and Wang, W. (2023). Nano-hydroxyapatite composite scaffolds loaded with bioactive factors and drugs for bone tissue engineering. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24021291"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"13348","DOI":"10.1039\/C9RA01168D","article-title":"Si, Sr, Ag co-doped hydroxyapatite\/TiO2 coating: Enhancement of its antibacterial activity and osteoinductivity","volume":"9","author":"Qiao","year":"2019","journal-title":"RSC Adv."},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Jebapriya, M., Venkatesan, R., Ansar, S., and Kim, S.-C. (2023). Enhancement of physicochemical characterization of nanocomposites on Ag+\/Fe2+ codoped hydroxyapatite for antibacterial and anticancer properties. Colloids Surf. B Biointerfaces, 229.","DOI":"10.1016\/j.colsurfb.2023.113463"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"20576","DOI":"10.1038\/s41598-022-24904-0","article-title":"In silico study on probing atomistic insights into structural stability and tensile properties of Fe-doped hydroxyapatite single crystals","volume":"12","author":"Basu","year":"2022","journal-title":"Sci. Rep."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1080\/03639045.2023.2193655","article-title":"Preparation and characterization of hydroxyapatite nanoparticles doped with nickel, tin, and molybdate ions for their antimicrobial effects","volume":"49","author":"Mollaei","year":"2023","journal-title":"Drug Dev. Ind. Pharm."},{"key":"ref_90","unstructured":"Surblyte, R., and Baltakys, K. (2023, January 10). Microwave synthesis of hydroxyapatite substituted with Zn2+ ions in the temperature range of 80\u2013200 \u00b0C. Proceedings of the Chemistry and Chemical Technology: International Conference CCT-2023, Vilnius, Lithuania."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"14783","DOI":"10.1016\/j.ceramint.2019.04.208","article-title":"The influence of simultaneous divalent cations (Mg2+, Co2+ and Sr2+) substitution on the physico-chemical properties of carbonated hydroxyapatite","volume":"45","author":"Syazwan","year":"2019","journal-title":"Ceram. Int."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"16104","DOI":"10.1016\/j.ceramint.2020.03.163","article-title":"The effects of Fe3+ and Co2+ substitution in Ca10-x-yFexCoy(PO4)6(OH)2 hydroxyapatite nanoparticles: Magnetic, antibacterial, and improved drug release behavior","volume":"46","author":"Pasandideh","year":"2020","journal-title":"Ceram. Int."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1007\/s10904-018-0864-1","article-title":"Study of in vitro bioactivity of nano hydroxyapatite composites doped by various cations","volume":"28","author":"Heshmatpour","year":"2018","journal-title":"J. Inorg. Organomet. Polym. Mater."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.surfcoat.2016.02.042","article-title":"Improving the bioactivity and corrosion resistance properties of electrodeposited hydroxyapatite coating by dual doping of bivalent strontium and manganese ion","volume":"291","author":"Huang","year":"2016","journal-title":"Surf. Coatings Technol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1111\/ijac.13229","article-title":"Multisubstituted hydroxyapatite powders and coatings: The influence of the codoping on the hydroxyapatite performances","volume":"16","author":"Cacciotti","year":"2019","journal-title":"Int. J. Appl. Ceram. Technol."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"13082","DOI":"10.1016\/j.ceramint.2018.04.128","article-title":"Nanoemulsion synthesis of carbonated hydroxyapatite nanopowders: Effect of variant CO32\u2212\/PO43\u2212 molar ratios on phase, morphology, and bioactivity","volume":"44","author":"Ezekiel","year":"2018","journal-title":"Ceram. Int."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"103734","DOI":"10.1016\/j.mtcomm.2022.103734","article-title":"Biocompatible magnetic hydroxyapatite Fe3O4-HAp nanocomposites for T1-magnetic resonance imaging guided photothermal therapy of breast cancer","volume":"31","author":"Mushtaq","year":"2022","journal-title":"Mater. Today Commun."},{"key":"ref_98","doi-asserted-by":"crossref","unstructured":"Govindan, B., Latha, B.S., Nagamony, P., Ahmed, F., Alam Saifi, M., Harrath, A.H., Alwasel, S., Mansour, L., and Alsharaeh, E.H. (2017). Designed synthesis of nanostructured magnetic hydroxyapatite based drug nanocarrier for anti-cancer drug delivery toward the treatment of human epidermoid carcinoma. Nanomaterials, 7.","DOI":"10.3390\/nano7060138"},{"key":"ref_99","doi-asserted-by":"crossref","unstructured":"Mondal, S., Manivasagan, P., Bharathiraja, S., Moorthy, M.S., Nguyen, V.T., Kim, H.H., Nam, S.Y., Lee, K.D., and Oh, J. (2017). Hydroxyapatite coated iron oxide nanoparticles: A promising nanomaterial for magnetic hyperthermia cancer treatment. Nanomaterials, 7.","DOI":"10.3390\/nano7120426"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.actbio.2011.09.032","article-title":"Intrinsic magnetism and hyperthermia in bioactive Fe-doped hydroxyapatite","volume":"8","author":"Tampieri","year":"2012","journal-title":"Acta Biomater."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.1021\/cm4007298","article-title":"Magnetic bioactive and biodegradable hollow fe-doped hydroxyapatite coated poly(l-lactic) acid micro-nanospheres","volume":"25","author":"Iafisco","year":"2013","journal-title":"Chem. Mater."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.actbio.2018.04.040","article-title":"On the use of superparamagnetic hydroxyapatite nanoparticles as an agent for magnetic and nuclear in vivo imaging","volume":"73","author":"Adamiano","year":"2018","journal-title":"Acta Biomater."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1111\/jace.17861","article-title":"A critical review of bioceramics for magnetic hyperthermia","volume":"105","author":"Sedighi","year":"2021","journal-title":"J. Am. Ceram. Soc."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.2217\/nnm-2018-0372","article-title":"Magnetic calcium phosphates nanocomposites for the intracellular hyperthermia of cancers of bone and brain","volume":"14","author":"Adamiano","year":"2019","journal-title":"Nanomedicine"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1700845","DOI":"10.1002\/adhm.201700845","article-title":"Advances in magnetic nanoparticles for biomedical applications","volume":"7","author":"Cardoso","year":"2018","journal-title":"Adv. Healthc. Mater."},{"key":"ref_106","first-page":"223","article-title":"Fabrication of Magnetic Hydroxyapatite by a Homogeneous Precipitation Method","volume":"6","author":"Yan","year":"2016","journal-title":"Mater. Sci."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.msec.2017.03.060","article-title":"Simplified preparation and characterization of magnetic hydroxyapatite-based nanocomposites","volume":"76","author":"Scialla","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.msec.2018.12.148","article-title":"Controlled nanoparticle synthesis of Ag\/Fe co-doped hydroxyapatite system for cancer cell treatment","volume":"98","author":"Veerla","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1111\/jace.12746","article-title":"Fabrication of a novel biocompatible magnetic biomaterial with hyperthermia potential","volume":"97","author":"Karunamoorthi","year":"2013","journal-title":"J. Am. Ceram. Soc."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.jmst.2013.10.011","article-title":"Synthesis and characterization of nano-hydroxyapatite powder using wet chemical precipitation reaction","volume":"30","author":"Abidi","year":"2014","journal-title":"J. Mater. Sci. Technol."},{"key":"ref_111","first-page":"144802","article-title":"Impact of different transition metal ions in the structural, mechanical, optical, chemico-physical and biological properties of nanohydroxyapatite","volume":"506","author":"Panneerselvam","year":"2019","journal-title":"Appl. Surf. Sci."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"125440","DOI":"10.1016\/j.matchemphys.2021.125440","article-title":"Effects of physico-chemical properties of ions-doped hydroxyapatite on adsorption and release performance of doxorubicin as a model anticancer drug","volume":"276","author":"Jiang","year":"2021","journal-title":"Mater. Chem. Phys."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"224","DOI":"10.3389\/fmats.2020.00224","article-title":"Enhancement of the biological and mechanical performances of sintered hydroxyapatite by multiple ions doping","volume":"7","author":"Sprio","year":"2020","journal-title":"Front. Mater."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.microc.2018.10.007","article-title":"Co-doped hydroxyapatites as potential materials for biomedical applications","volume":"144","author":"Yilmaz","year":"2018","journal-title":"Microchem. J."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"13773","DOI":"10.1039\/C7NJ01777D","article-title":"Physico-mechanical properties of Mg and Ag doped hydroxyapatite\/chitosan biocomposites","volume":"41","author":"Mansour","year":"2017","journal-title":"New J. Chem."},{"key":"ref_116","first-page":"327","article-title":"Effects of doping metal nanoparticles in hydroxyapatite in Improving the physical and chemical properties of dental implants","volume":"6","author":"Tosan","year":"2021","journal-title":"Nanomed. Res. J."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1007\/s10856-012-4767-3","article-title":"Magnesium- and strontium-co-substituted hydroxyapatite: The effects of doped-ions on the structure and chemico-physical properties","volume":"23","author":"Aina","year":"2012","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1016\/j.ceramint.2018.11.003","article-title":"Effect of multi-ions doping on the properties of carbonated hydroxyapatite bioceramic","volume":"45","author":"Safarzadeh","year":"2018","journal-title":"Ceram. Int."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ymeth.2021.04.018","article-title":"Magnetite nanoparticles: Synthesis methods\u2014A comparative review","volume":"199","author":"Niculescu","year":"2022","journal-title":"Methods"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1007\/s12668-022-00996-w","article-title":"Methods of chemical synthesis in the synthesis of nanomaterial and nanoparticles by the chemical deposition method: A review","volume":"12","author":"Hachem","year":"2022","journal-title":"BioNanoScience"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"033057","DOI":"10.1088\/1757-899X\/688\/3\/033057","article-title":"Three common preparation methods of hydroxyapatite","volume":"688","author":"Ma","year":"2019","journal-title":"IOP Conf. Ser. Mater. Sci. Eng."},{"key":"ref_122","doi-asserted-by":"crossref","unstructured":"Ignatovich, Z., Novik, K., Abakshonok, A., Koroleva, E., Beklemisheva, A., Panina, L., Kaniukov, E., Anisovich, M., and Shumskaya, A. (2021). One-Step Synthesis of Magnetic Nanocomposite with Embedded Biologically Active Substance. Molecules, 26.","DOI":"10.3390\/molecules26040937"},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"321","DOI":"10.2298\/PAC2004321J","article-title":"Influence of wet chemical processing conditions on structure and properties of magnetic hydroxyapatite nanocomposites","volume":"14","author":"Jakab","year":"2020","journal-title":"Process. Appl. Ceram."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"012018","DOI":"10.1088\/1757-899X\/1053\/1\/012018","article-title":"The Effect of Addition of F3O4 and Sintering Temperature on Properties of the Magnetite\/Hydroxyapatite Particles Produced through the Coprecipitation Technique","volume":"1053","author":"Fadli","year":"2021","journal-title":"IOP Conf. Ser. Mater. Sci. Eng."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"110633","DOI":"10.1016\/j.msec.2020.110633","article-title":"Impact of structural features of Sr\/Fe co-doped HAp on the osteoblast proliferation and osteogenic differentiation for its application as a bone substitute","volume":"110","author":"Ullah","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1021\/acsbiomaterials.9b01666","article-title":"Synthesis and characterization of sintered Sr\/Fe-modified hydroxyapatite bioceramics for bone tissue engineering applications","volume":"6","author":"Ullah","year":"2019","journal-title":"ACS Biomater. Sci. Eng."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/s40145-012-0012-2","article-title":"Application of mechanochemical synthesis of advanced materials","volume":"1","author":"Wu","year":"2012","journal-title":"J. Adv. Ceram."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"6698","DOI":"10.1039\/C4CC09876E","article-title":"Mechanochemical synthesis of advanced nanomaterials for catalytic applications","volume":"51","author":"Xu","year":"2015","journal-title":"Chem. Commun."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1039\/C1CS15171A","article-title":"Mechanochemistry: Opportunities for new and cleaner synthesis","volume":"41","author":"James","year":"2011","journal-title":"Chem. Soc. Rev."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.powtec.2006.03.021","article-title":"Mechanochemical synthesis of the nanocrystalline semiconductors in an industrial mill","volume":"164","author":"Gock","year":"2006","journal-title":"Powder Technol."},{"key":"ref_131","first-page":"99","article-title":"Preparation and characterization of an iron oxide-hydroxyapatite nanocomposite for potential bone cancer therapy","volume":"10","author":"Sneha","year":"2015","journal-title":"Int. J. Nanomed."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"9365","DOI":"10.3390\/ijms14059365","article-title":"Simple and rapid synthesis of magnetite\/hydroxyapatite composites for hyperthermia treatments via a mechanochemical route","volume":"14","author":"Iwasaki","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1134\/S1027451023030266","article-title":"Substitution in the Structure of Hydroxyapatite Doped with Iron Cations upon Mechanochemical Synthesis","volume":"17","author":"Isaev","year":"2023","journal-title":"J. Surf. Investig. X-ray Synchrotron Neutron Tech."},{"key":"ref_134","unstructured":"Iwasaki, T. (2013). Materials Science-Advanced Topics, IntechOpen."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10856-016-5704-7","article-title":"Spherical porous hydroxyapatite granules containing composites of magnetic and hydroxyapatite nanoparticles for the hyperthermia treatment of bone tumor","volume":"27","author":"Kamitakahara","year":"2016","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3390\/powders2020022","article-title":"Thermal Stability of Iron- and Silicon-Substituted Hydroxyapatite Prepared by Mechanochemical Method","volume":"2","author":"Makarova","year":"2023","journal-title":"Powders"},{"key":"ref_137","doi-asserted-by":"crossref","unstructured":"Goldberg, M.A., Gafurov, M.R., Murzakhanov, F.F., Fomin, A.S., Antonova, O.S., Khairutdinova, D.R., and Komlev, V.S. (2021). Mesoporous iron (III)-doped hydroxyapatite nanopowders obtained via iron oxalate. Nanomaterials, 11.","DOI":"10.3390\/nano11030811"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.actbio.2010.08.023","article-title":"Hydroxyapatite\/biodegradable poly (l-lactide\u2013co-\u03b5-caprolactone) composite microparticles as injectable scaffolds by a Pickering emulsion route","volume":"7","author":"Liu","year":"2011","journal-title":"Acta Biomater."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"110962","DOI":"10.1016\/j.msec.2020.110962","article-title":"One-step hydrothermal synthesis with in situ milling of biologically relevant hydroxyapatite","volume":"113","author":"Chesley","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"3928","DOI":"10.1016\/j.ceramint.2020.09.256","article-title":"Novel green synthesis of hydroxyapatite uniform nanorods via microwave-hydrothermal route using licorice root extract as template","volume":"47","author":"Ali","year":"2020","journal-title":"Ceram. Int."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"950","DOI":"10.2109\/jcersj2.116.950","article-title":"Hydrothermal synthesis of magnetite\/hydroxyapatite composite material for hyperthermia therapy for bone cancer","volume":"116","author":"Murakami","year":"2008","journal-title":"J. Ceram. Soc. Jpn."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"147352","DOI":"10.1016\/j.apsusc.2020.147352","article-title":"Fe3O4@HAp core\u2013shell nanoparticles as MRI contrast agent: Synthesis, characterization and theoretical and experimental study of shell impact on magnetic properties","volume":"531","author":"Zheltova","year":"2020","journal-title":"Appl. Surf. Sci."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"2302595","DOI":"10.1155\/2016\/2302595","article-title":"Review of research on template methods in preparation of nanomaterials","volume":"2016","author":"Xie","year":"2016","journal-title":"J. Nanomater."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.1039\/C2CS35369E","article-title":"Templated synthesis of nanostructured materials","volume":"42","author":"Liu","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s12034-016-1165-3","article-title":"Synthesis and characterization of magnetite\/hydroxyapatite tubes using natural template for biomedical applications","volume":"39","author":"Sneha","year":"2016","journal-title":"Bull. Mater. Sci."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1007\/s10856-010-4090-9","article-title":"Aqueous ferrofluids as templates for magnetic hydroxyapatite nanocomposites","volume":"21","author":"Mir","year":"2010","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.matlet.2012.01.129","article-title":"A novel preparation of magnetic hydroxyapatite nanotubes","volume":"75","author":"Singh","year":"2012","journal-title":"Mater. Lett."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"9332","DOI":"10.1039\/C5CC02259B","article-title":"Al(OH)3 facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles","volume":"51","author":"Cui","year":"2015","journal-title":"Chem. Commun."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"6228","DOI":"10.1039\/C9RA00051H","article-title":"Tailoring the morphological features of sol\u2013gel synthesized mesoporous hydroxyapatite using fatty acids as an organic modifier","volume":"9","author":"Lett","year":"2019","journal-title":"RSC Adv."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1007\/s10971-018-4910-9","article-title":"Structural characterization and antibacterial activity of hydroxyapatite synthesized via sol-gel method using glutinous rice as a template","volume":"89","author":"Phatai","year":"2019","journal-title":"J. Sol-Gel Sci. Technol."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"122337","DOI":"10.1016\/j.matchemphys.2019.122337","article-title":"Catechin adsorption on magnetic hydroxyapatite nanoparticles: A synergistic interaction with calcium ions","volume":"241","author":"Yusoff","year":"2019","journal-title":"Mater. Chem. Phys."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1380\/ejssnt.2017.121","article-title":"Synthesis of superparamagnetic hydroxyapatite core-shell nanostructure by a rapid sol-gel route","volume":"15","author":"Yusoff","year":"2017","journal-title":"e-J. Surf. Sci. Nanotechnol."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"131911","DOI":"10.1016\/j.colsurfa.2023.131911","article-title":"Facile Synthesis of Metformin Loaded Mn3O4-HAp Magnetic Hydroxyapatite Nanocomposites for T1-Magnetic Resonance Imaging Guided Targeted Chemo-Phototherapy In Vitro","volume":"674","author":"Mushtaq","year":"2023","journal-title":"Colloids Surfaces A Physicochem. Eng. Asp."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"12860","DOI":"10.1016\/j.ceramint.2019.03.209","article-title":"Development of multifunctional cobalt ferrite\/hydroxyapatite nanocomposites by microwave assisted wet precipitation method: A promising platform for synergistic chemo-hyperthermia therapy","volume":"45","author":"Sangeetha","year":"2019","journal-title":"Ceram. Int."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"169544","DOI":"10.1016\/j.jallcom.2023.169544","article-title":"Microwave-assisted hydrothermal synthesis of Fe-doped 1T\/2H-MoS2 few-layer nanosheets for efficient electromagnetic wave absorbing","volume":"947","author":"Zhang","year":"2023","journal-title":"J. Alloys Compd."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"3725","DOI":"10.1016\/j.ceramint.2015.11.044","article-title":"Microwave-assisted preparation of Nano-hydroxyapatite for bone substitutes","volume":"42","author":"Hassan","year":"2016","journal-title":"Ceram. Int."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1039\/c3bm60086f","article-title":"Magnetic nanocomposite of hydroxyapatite ultrathin nanosheets\/Fe3O4 nanoparticles: Microwave-assisted rapid synthesis and application in pH-responsive drug release","volume":"1","author":"Chen","year":"2013","journal-title":"Biomater. Sci."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"15143","DOI":"10.1016\/j.ceramint.2019.04.256","article-title":"Sodium dodecyl sulfate mediated microwave synthesis of biocompatible superparamagnetic mesoporous hydroxyapatite nanoparticles using black Chlamys varia seashell as a calcium source for biomedical applications","volume":"45","author":"Karunakaran","year":"2019","journal-title":"Ceram. Int."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"165564","DOI":"10.1016\/j.ijleo.2020.165564","article-title":"Surfactant-assisted microwave synthesis of luminescent\/magnetic bifunctional hydroxyapatite nanorods for dual-model imaging","volume":"225","author":"Agalya","year":"2020","journal-title":"Optik"},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"13153","DOI":"10.1016\/j.ceramint.2015.07.088","article-title":"Synthesis of magnetic hydroxyapatite by hydrothermal\u2013microwave technique: Dielectric, protein adsorption, blood compatibility and drug release studies","volume":"41","author":"Chandra","year":"2015","journal-title":"Ceram. Int."},{"key":"ref_161","doi-asserted-by":"crossref","unstructured":"Iglesias, G.R., Jabalera, Y., Peigneux, A., Fern\u00e1ndez, B.L.C., Delgado, V., and Jimenez-Lopez, C. (2019). Enhancement of magnetic hyperthermia by mixing synthetic inorganic and biomimetic magnetic nanoparticles. Pharmaceutics, 11.","DOI":"10.3390\/pharmaceutics11060273"},{"key":"ref_162","doi-asserted-by":"crossref","unstructured":"Drozdov, A.S., Komarova, K.S., Mochalova, E.N., Komedchikova, E.N., Shipunova, V.O., and Nikitin, M.P. (2022). Fluorescent magnetic nanoparticles for bioimaging through biomimetic surface modification. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24010134"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3389\/fmats.2019.00313","article-title":"Additive manufacturing methods for producing hydroxyapatite and hydroxyapatite-based composite scaffolds: A review","volume":"6","author":"Kumar","year":"2019","journal-title":"Front. Mater."},{"key":"ref_164","first-page":"697","article-title":"Novel synthesis and characterization of an AB-type carbonate-substituted hydroxyapatite","volume":"59","author":"Gibson","year":"2002","journal-title":"J. Biomed. Mater. Res. Off. J. Soc. Biomater. Jpn. Soc. Biomater. Aust. Soc. Biomater. Korean Soc. Biomater."},{"key":"ref_165","first-page":"57","article-title":"Preparation and characterization of microcrystalline hydroxyapatite using sol gel method","volume":"19","author":"Vijayalakshmi","year":"2006","journal-title":"Trends Biomater. Artif. Organs"},{"key":"ref_166","unstructured":"Luz, G., and Mano, J. (2014). Tissue Engineering Using Ceramics and Polymers, Elsevier."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1039\/jm9950500935","article-title":"Biomineralization and biomimetic materials chemistry","volume":"5","author":"Mann","year":"1995","journal-title":"J. Mater. Chem."},{"key":"ref_168","doi-asserted-by":"crossref","unstructured":"Strbak, O., Hnilicova, P., Gombos, J., Lokajova, A., and Kopcansky, P. (2022). Magnetotactic bacteria: From evolution to biomineralization and biomedical applications. Minerals, 12.","DOI":"10.3390\/min12111403"},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"110450","DOI":"10.1016\/j.inoche.2023.110450","article-title":"Evaluation of bone-like apatite biomineralization on biomimetic graphene oxide\/hydroxyapatite nanocomposite","volume":"149","author":"Hakimi","year":"2023","journal-title":"Inorg. Chem. Commun."},{"key":"ref_170","doi-asserted-by":"crossref","unstructured":"Tithito, T., Sillapaprayoon, S., Pimtong, W., Thongbunchoo, J., Charoenphandhu, N., Krishnamra, N., Lert-Itthiporn, A., Maneeprakorn, W., and Pon-On, W. (2023). Development of Biomaterials Based on Biomimetic Trace Elements Co-Doped Hydroxyapatite: Physical, In Vitro Osteoblast-like Cell Growth and In Vivo Cytotoxicity in Zebrafish Studies. Nanomaterials, 13.","DOI":"10.3390\/nano13020255"},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"27866","DOI":"10.1016\/j.ceramint.2020.07.285","article-title":"Biosynthesis and characterization of nano magnetic hydroxyapatite (nMHAp): An accelerated approach using simulated body fluid for biomedical applications","volume":"46","author":"Bhatt","year":"2020","journal-title":"Ceram. Int."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s40201-023-00869-8","article-title":"Antibiotic photocatalysis and antimicrobial activity of low-cost multifunctional Fe3O4@HAp nanocomposites","volume":"21","author":"Labrag","year":"2023","journal-title":"J. Environ. Health Sci. Eng."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"045006","DOI":"10.1088\/2053-1591\/acca65","article-title":"Synthesis of iron-substituted hydroxyapatite nanomaterials by co-precipitation method for defluoridation","volume":"10","author":"Adamu","year":"2023","journal-title":"Mater. Res. Express"},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"110213","DOI":"10.1016\/j.jece.2023.110213","article-title":"Spongy magnetic hydroxyapatite for the enhanced Pb2+ removal and its dynamic sorption mechanism","volume":"11","author":"Zhou","year":"2023","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_175","doi-asserted-by":"crossref","unstructured":"Wu, S.-C., Hsu, H.-C., Wang, H.-F., Liou, S.-P., and Ho, W.-F. (2023). Synthesis and characterization of nano-hydroxyapatite obtained from eggshell via the hydrothermal process and the precipitation method. Molecules, 28.","DOI":"10.3390\/molecules28134926"},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.saa.2011.11.047","article-title":"Synthesis and spectroscopic characterization of magnetic hydroxyapatite nanocomposite using ultrasonic irradiation","volume":"87","author":"Gopi","year":"2012","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"e04928","DOI":"10.1016\/j.heliyon.2020.e04928","article-title":"One-pot hydrothermal synthesis of a magnetic hydroxyapatite nanocomposite for MR imaging and pH-Sensitive drug delivery applications","volume":"6","author":"Kermanian","year":"2020","journal-title":"Heliyon"},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s10450-017-9931-0","article-title":"Facile synthesis of magnetic hydroxyapatite-supported nickel oxide nanocomposite and its dye adsorption characteristics","volume":"24","author":"Phasuk","year":"2017","journal-title":"Adsorption"},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00723-014-0613-8","article-title":"EPR and Optical Studies of Fe3+-Doped Ca\u2013Li Hydroxyapatite Nanopowder: Mechanochemical Synthesis","volume":"46","author":"Ravindranadh","year":"2014","journal-title":"Appl. Magn. Reson."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"2102120","DOI":"10.1002\/admi.202102120","article-title":"Tunable Hydroxyapatite\/Magnetite Nanohybrids with Preserved Magnetic Properties","volume":"9","author":"Ayesh","year":"2022","journal-title":"Adv. Mater. Interfaces"},{"key":"ref_181","first-page":"90","article-title":"Mechanical properties of the hydroxyapatite and magnetic nanocomposite of hydroxyapatite adsorbents","volume":"33","author":"Vahdat","year":"2020","journal-title":"S. Afr. J. Chem. Eng."},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"210","DOI":"10.2298\/PAC1902210V","article-title":"Hydroxyapatite\/iron oxide nanocomposite prepared by high energy ball milling","volume":"13","author":"Antic","year":"2019","journal-title":"Process. Appl. Ceram."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1021\/acs.langmuir.0c02408","article-title":"Dual stimuli-responsive pickering emulsions from novel magnetic hydroxyapatite nanoparticles and their characterization using a microfluidic platform","volume":"37","author":"Mendiratta","year":"2021","journal-title":"Langmuir"},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"128347","DOI":"10.1016\/j.colsurfa.2022.128347","article-title":"One-step preparation of hydroxyapatite-loaded magnetic Polycaprolactone hollow microspheres for malachite green adsorption by Pickering emulsion template method","volume":"639","author":"Yan","year":"2022","journal-title":"Colloids Surfaces A Physicochem. Eng. Asp."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"135062","DOI":"10.1016\/j.matlet.2023.135062","article-title":"Synthesis of chitosan\/hydroxyapatite\/Fe3O4 microspheres with NIR-induced antibacterial property","volume":"351","author":"Zhang","year":"2023","journal-title":"Mater. Lett."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"11816","DOI":"10.1039\/c3ra45896b","article-title":"Emulsion fabrication of magnetic mesoporous carbonated hydroxyapatite microspheres for treatment of bone infection","volume":"4","author":"Long","year":"2014","journal-title":"RSC Adv."},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"223","DOI":"10.4028\/www.scientific.net\/KEM.529-530.223","article-title":"A Novel Approach to Prepare Hydroxyapatite-Coated Biodegradable Polymer Microspheres Loaded with Magnetic Fe3O4 via Nanoparticle-Stabilized Emulsions","volume":"529\u2013530","author":"Okada","year":"2012","journal-title":"Key Eng. Mater."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jmmm.2015.01.075","article-title":"Microemulsion synthesis and magnetic properties of hydroxyapatite-encapsulated nano CoFe2O4","volume":"382","author":"Foroughi","year":"2015","journal-title":"J. Magn. Magn. Mater."},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"141474","DOI":"10.1016\/j.cej.2023.141474","article-title":"In-situ hydrothermal synthesis of Fe-doped hydroxyapatite photocatalyst derived from converter slag toward xanthate photodegradation and Cr(VI) reduction under visible-light irradiation","volume":"459","author":"Shu","year":"2023","journal-title":"Chem. Eng. J."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1039\/c3tb21769h","article-title":"Magnetic hydroxyapatite coatings with oriented nanorod arrays: Hydrothermal synthesis, structure and biocompatibility","volume":"2","author":"Chen","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"ref_191","first-page":"39","article-title":"Hydrothermal synthesis of cobalt-doped hydroxyapatite nanoparticles: Structure, magnetic behaviour, bioactivity and antibacterial activity","volume":"16","author":"Yazdani","year":"2019","journal-title":"Iran. J. Mater. Sci. Eng."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/j.jece.2018.01.007","article-title":"Hydrothermal assisted magnetic nano-hydroxyapatite encapsulated alginate beads for efficient Cr(VI) uptake from water","volume":"6","author":"Periyasamy","year":"2018","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"130513","DOI":"10.1016\/j.colsurfa.2022.130513","article-title":"ROS-responsive chlorin e6 and silk fibroin loaded ultrathin magnetic hydroxyapatite nanorods for T1-magnetic resonance imaging guided photodynamic therapy in vitro","volume":"656","author":"Mushtaq","year":"2023","journal-title":"Colloids Surfaces A Physicochem. Eng. Asp."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1039\/C8EW00027A","article-title":"Fabrication of magnetic particles reinforced nano-hydroxyapatite\/gelatin composite for selective Cr(vi) removal from water","volume":"4","author":"Gopalakannan","year":"2018","journal-title":"Environ. Sci. Water Res. Technol."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1039\/c3tb21829e","article-title":"Hydrothermal fabrication of magnetic mesoporous carbonated hydroxyapatite microspheres: Biocompatibility, osteoinductivity, drug delivery property and bactericidal property","volume":"2","author":"Guo","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.matlet.2019.06.059","article-title":"Synthesis of magnetic Fe-doped hydroxyapatite nanocages with highly efficient and selective adsorption for Cd2+","volume":"253","author":"Guo","year":"2019","journal-title":"Mater. Lett."},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.matlet.2011.10.079","article-title":"Preparation and characterization of a novel laminated magnetic hydroxyapatite for application on gene delivery","volume":"68","author":"Zuo","year":"2011","journal-title":"Mater. Lett."},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s10856-015-5393-7","article-title":"In situ synthesis of hydroxyapatite nanocomposites using iron oxide nanofluids at ambient conditions","volume":"26","author":"Sheikh","year":"2015","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1007\/s10967-020-07148-y","article-title":"Magnetic solid-phase extraction of U(VI) in aqueous solution by Fe3O4@hydroxyapatite","volume":"324","author":"Zeng","year":"2020","journal-title":"J. Radioanal. Nucl. Chem."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"9395","DOI":"10.1016\/j.ceramint.2014.02.009","article-title":"Dielectric properties of Fe doped hydroxyapatite prepared by sol\u2013gel method","volume":"40","author":"Dorozhkin","year":"2014","journal-title":"Ceram. Int."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.colsurfa.2018.07.036","article-title":"Magnetic \u03b3-Fe2O3\/Fe-doped hydroxyapatite nanostructures as high-efficiency cadmium adsorbents","volume":"555","author":"Xiao","year":"2018","journal-title":"Colloids Surf. A Physicochem. Eng. Asp."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.apt.2015.07.002","article-title":"Synthesis and characterization of iron-doped\/substituted calcium hydroxyapatite from seashells Macoma balthica (L.)","volume":"26","author":"Prichodko","year":"2015","journal-title":"Adv. Powder Technol."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"10997","DOI":"10.1039\/C5RA21479C","article-title":"Preparation and characterization of novel Ag doped hydroxyapatite\u2013Fe3O4\u2013chitosan hybrid composites and in vitro biological evaluations for orthopaedic applications","volume":"6","author":"Anjaneyulu","year":"2016","journal-title":"RSC Adv."},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1049\/iet-nbt.2017.0029","article-title":"Development and characterisation of novel Ce-doped hydroxyapatite\u2013Fe3O4 nanocomposites and their in vitro biological evaluations for biomedical applications","volume":"12","author":"Baskaran","year":"2018","journal-title":"IET Nanobiotechnol."},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"5901","DOI":"10.1166\/asl.2018.12217","article-title":"Preparation of Ag doped hydroxyapatite-Fe3O4-Chitosan composites: In vitro biocompatibility study on MG-63 cells for orthopedic applications","volume":"24","author":"Anjaneyulu","year":"2018","journal-title":"Adv. Sci. Lett."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"8219","DOI":"10.1007\/s10853-017-1038-1","article-title":"Ag@Fe3O4@cellulose nanocrystals nanocomposites: Microwave-assisted hydrothermal synthesis, antimicrobial properties, and good adsorption of dye solution","volume":"52","author":"Dong","year":"2017","journal-title":"J. Mater. Sci."},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.materresbull.2014.06.018","article-title":"Mesoporous Fe3O4\/hydroxyapatite composite for targeted drug delivery","volume":"59","author":"Gu","year":"2014","journal-title":"Mater. Res. Bull."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.cclet.2016.06.022","article-title":"Preparation of a novel, efficient, and recyclable magnetic catalyst, \u03b3-Fe2O3@ HAp-Ag nanoparticles, and a solvent-and halogen-free protocol for the synthesis of coumarin derivatives","volume":"28","author":"Abbasi","year":"2017","journal-title":"Chin. Chem. Lett."},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s00339-023-06477-5","article-title":"Influence of phase ratio on structural, magnetic, and microwave characteristics of hard\/soft SrEr0.01Cr0.01Fe11.98O19\/NiFe2O4 magnetic nanocomposites","volume":"129","author":"Almessiere","year":"2023","journal-title":"Appl. Phys. A"},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1007\/s13738-020-01883-5","article-title":"Synthesis of a novel magnetic zeolite\u2013hydroxyapatite adsorbent via microwave-assisted method for protein adsorption via magnetic solid-phase extraction","volume":"17","author":"Piri","year":"2019","journal-title":"J. Iran. Chem. Soc."},{"key":"ref_211","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.matpr.2021.01.421","article-title":"Synthesis and characterization of Fe and Eu containing hydroxyapataite","volume":"46","author":"Saikiran","year":"2021","journal-title":"Mater. Today Proc."},{"key":"ref_212","doi-asserted-by":"crossref","first-page":"8642","DOI":"10.1016\/j.ceramint.2020.11.234","article-title":"Microwave-assisted synthesis of superparamagnetic mesoporous Co-doped hydroxyapatite nanorods for various biomedical applications","volume":"47","author":"Karunakaran","year":"2020","journal-title":"Ceram. Int."},{"key":"ref_213","doi-asserted-by":"crossref","first-page":"103338","DOI":"10.1016\/j.jece.2019.103338","article-title":"Enhanced adsorption of dyes on microwave-assisted synthesized magnetic zeolite-hydroxyapatite nanocomposite","volume":"7","author":"Piri","year":"2019","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_214","doi-asserted-by":"crossref","first-page":"111310","DOI":"10.1016\/j.msec.2020.111310","article-title":"In vitro study of a novel multi-substituted hydroxyapatite nanopowder synthesized by an ultra-fast, efficient and green microwave-assisted method","volume":"117","author":"Kheradmandfard","year":"2020","journal-title":"Mater. Sci. Eng."},{"key":"ref_215","doi-asserted-by":"crossref","first-page":"110169","DOI":"10.1016\/j.enzmictec.2022.110169","article-title":"Biomimetic one-pot preparation of surface biofunctionalized silica-coated magnetic composites for dual enzyme oriented immobilization without pre-purification","volume":"164","author":"Ge","year":"2023","journal-title":"Enzym. Microb. Technol."},{"key":"ref_216","doi-asserted-by":"crossref","first-page":"153","DOI":"10.14723\/tmrsj.43.153","article-title":"Biomimetic Method for Production of Magnetic Hydroxyapatite Microcapsules for Enzyme Immobilization","volume":"43","author":"Yamamoto","year":"2018","journal-title":"Trans. Mater. Res. Soc. Jpn."},{"key":"ref_217","doi-asserted-by":"crossref","first-page":"15697","DOI":"10.1021\/am5050967","article-title":"Magnetic bioinspired hybrid nanostructured collagen\u2013hydroxyapatite scaffolds supporting cell proliferation and tuning regenerative process","volume":"6","author":"Tampieri","year":"2014","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_218","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/1097-4636(200011)52:2<270::AID-JBM5>3.0.CO;2-1","article-title":"Calcium and phosphate supplementation promotes bone cell mineralization: Implications for hydroxyapatite (HA)-enhanced bone formation","volume":"52","author":"Chang","year":"2000","journal-title":"J. Biomed. Mater. Res."},{"key":"ref_219","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.biomaterials.2018.08.040","article-title":"Magnetic field and nano-scaffolds with stem cells to enhance bone regeneration","volume":"183","author":"Xia","year":"2018","journal-title":"Biomaterials"},{"key":"ref_220","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.biomaterials.2016.01.035","article-title":"Magnetic nanocomposite scaffolds combined with static magnetic field in the stimulation of osteoblastic differentiation and bone formation","volume":"85","author":"Yun","year":"2016","journal-title":"Biomaterials"},{"key":"ref_221","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s11517-010-0639-5","article-title":"Static magnetic field exposure promotes differentiation of osteoblastic cells grown on the surface of a poly-l-lactide substrate","volume":"48","author":"Feng","year":"2010","journal-title":"Med. Biol. Eng. Comput."},{"key":"ref_222","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.pbiomolbio.2022.11.006","article-title":"Evidence of the static magnetic field effects on bone-related diseases and bone cells","volume":"177","author":"Yang","year":"2023","journal-title":"Prog. Biophys. Mol. Biol."},{"key":"ref_223","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jare.2018.06.003","article-title":"A review on the use of magnetic fields and ultrasound for non-invasive cancer treatment","volume":"14","author":"Sengupta","year":"2018","journal-title":"J. Adv. Res."},{"key":"ref_224","doi-asserted-by":"crossref","first-page":"7979","DOI":"10.2147\/IJN.S275650","article-title":"Exosomes derived from bone mesenchymal stem cells with the stimulation of Fe3O4 nanoparticles and static magnetic field enhance wound healing through upregulated miR-21-5p","volume":"15","author":"Wu","year":"2020","journal-title":"Int. J. Nanomed."},{"key":"ref_225","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41579-020-0420-1","article-title":"Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections","volume":"19","author":"Makabenta","year":"2020","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_226","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1080\/0955300031000096289","article-title":"Strong static magnetic field and the induction of mutations through elevated production of reactive oxygen species in Escherichia coli soxR","volume":"79","author":"Zhang","year":"2003","journal-title":"Int. J. Radiat. Biol."},{"key":"ref_227","doi-asserted-by":"crossref","first-page":"124","DOI":"10.3389\/fchem.2020.00124","article-title":"Recent Advances on Magnetic Sensitive Hydrogels in Tissue Engineering","volume":"8","author":"Liu","year":"2020","journal-title":"Front. Chem."},{"key":"ref_228","first-page":"126","article-title":"1\u20132 T static magnetic field combined with Ferumoxytol prevent unloading-induced bone loss by regulating iron metabolism in osteoclastogenesis","volume":"38","author":"Zhang","year":"2022","journal-title":"J. Orthop. Transl."},{"key":"ref_229","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jmmm.2015.09.004","article-title":"The effect of low static magnetic field on osteogenic and adipogenic differentiation potential of human adipose stromal\/stem cells","volume":"398","author":"Tomaszewski","year":"2016","journal-title":"J. Magn. Magn. Mater."},{"key":"ref_230","first-page":"213028","article-title":"Tension exerted on cells by magnetic nanoparticles regulates differentiation of human mesenchymal stem cells","volume":"139","author":"Cho","year":"2022","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_231","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1007\/s12011-017-1161-5","article-title":"Regulation of osteoblast differentiation and iron content in MC3T3-E1 cells by static magnetic field with different intensities","volume":"184","author":"Yang","year":"2017","journal-title":"Biol. Trace Element Res."},{"key":"ref_232","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/jbm.b.33836","article-title":"Bone regeneration in a rabbit critical femoral defect by means of magnetic hydroxyapatite macroporous scaffolds","volume":"106","author":"Russo","year":"2017","journal-title":"J. Biomed. Mater. Res. Part B Appl. Biomater."},{"key":"ref_233","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1166\/jbn.2015.2065","article-title":"Towards the design of 3D fiber-deposited poly (-caprolactone)\/iron-doped hydroxyapatite nanocomposite magnetic scaffolds for bone regeneration","volume":"11","author":"Russo","year":"2015","journal-title":"J. Biomed. Nanotechnol."},{"key":"ref_234","doi-asserted-by":"crossref","first-page":"102401","DOI":"10.1016\/j.cis.2021.102401","article-title":"Hydroxyapatite with magnetic core: Synthesis methods, properties, adsorption and medical applications","volume":"291","author":"Biedrzycka","year":"2021","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_235","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.msec.2018.12.120","article-title":"Novel magnetic calcium phosphate-stem cell construct with magnetic field enhances osteogenic differentiation and bone tissue engineering","volume":"98","author":"Xia","year":"2018","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_236","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1007\/s42247-022-00430-7","article-title":"Magnetic hydroxyapatite bisphosphonate-based composites: A bone-targeting nanosystem","volume":"6","author":"Mostafa","year":"2022","journal-title":"Emergent Mater."},{"key":"ref_237","doi-asserted-by":"crossref","first-page":"106672","DOI":"10.1016\/j.compositesa.2021.106672","article-title":"Graphene Oxide-loaded magnetic nanoparticles within 3D hydrogel form High-performance scaffolds for bone regeneration and tumour treatment","volume":"152","author":"Li","year":"2021","journal-title":"Compos. Part A Appl. Sci. Manuf."},{"key":"ref_238","doi-asserted-by":"crossref","unstructured":"Shi, Z., Jia, L., Zhang, Q., Sun, L., Wang, X., Qin, X., and Xia, Y. (2023). An altered oral microbiota induced by injections of superparamagnetic iron oxide nanoparticle-labeled periodontal ligament stem cells helps periodontal bone regeneration in rats. Bioeng. Transl. Med., 8.","DOI":"10.1002\/btm2.10466"},{"key":"ref_239","doi-asserted-by":"crossref","first-page":"107986","DOI":"10.1016\/j.compositesb.2020.107986","article-title":"Magnetically actuated bone scaffold: Microstructure, cell response and osteogenesis","volume":"192","author":"Shuai","year":"2020","journal-title":"Composit. Part B Eng."},{"key":"ref_240","doi-asserted-by":"crossref","first-page":"44279","DOI":"10.1021\/acsami.8b17427","article-title":"Magnetic Cell\u2013Scaffold Interface Constructed by Superparamagnetic IONP Enhanced Osteogenesis of Adipose-Derived Stem Cells","volume":"10","author":"Chen","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_241","doi-asserted-by":"crossref","first-page":"108275","DOI":"10.1016\/j.matdes.2019.108275","article-title":"A magnetic micro-environment in scaffolds for stimulating bone regeneration","volume":"185","author":"Shuai","year":"2019","journal-title":"Mater. Des."},{"key":"ref_242","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.actbio.2009.09.017","article-title":"A novel route in bone tissue engineering: Magnetic biomimetic scaffolds","volume":"6","author":"Bock","year":"2010","journal-title":"Acta Biomater."},{"key":"ref_243","doi-asserted-by":"crossref","unstructured":"Mocanu-Dobranici, A.-E., Costache, M., and Dinescu, S. (2023). Insights into the Molecular Mechanisms Regulating Cell Behavior in Response to Magnetic Materials and Magnetic Stimulation in Stem Cell (Neurogenic) Differentiation. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24032028"},{"key":"ref_244","doi-asserted-by":"crossref","first-page":"118144","DOI":"10.1016\/j.ces.2022.118144","article-title":"Wet-electrospinning of nanofibrous magnetic composite 3-D scaffolds for enhanced stem cells neural differentiation","volume":"264","author":"Bakhtiary","year":"2022","journal-title":"Chem. Eng. Sci."},{"key":"ref_245","doi-asserted-by":"crossref","unstructured":"Mohd, N., Razali, M., Ghazali, M.J., and Abu Kasim, N.H. (2022). 3D-Printed Hydroxyapatite and Tricalcium Phosphates-Based Scaffolds for Alveolar Bone Regeneration in Animal Models: A Scoping Review. Materials, 15.","DOI":"10.3390\/ma15072621"},{"key":"ref_246","first-page":"2105002","article-title":"3D-printed synthetic hydroxyapatite scaffold with in silico optimized macrostructure enhances bone formation in vivo","volume":"32","author":"Liang","year":"2021","journal-title":"Adv. Funct. Mater."},{"key":"ref_247","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1002\/jbm.a.36823","article-title":"In vitro and in vivo biocompatibility of calcium-phosphate scaffolds three-dimensional printed by stereolithography for bone regeneration","volume":"108","author":"Plougonven","year":"2020","journal-title":"J. Biomed. Mater. Res. Part A"},{"key":"ref_248","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.proeng.2013.05.116","article-title":"Systematic Analysis of Injectable Materials and 3D Rapid Prototyped Magnetic Scaffolds: From CNS Applications to Soft and Hard Tissue Repair\/Regeneration","volume":"59","author":"Russo","year":"2013","journal-title":"Procedia Eng."},{"key":"ref_249","doi-asserted-by":"crossref","unstructured":"Panseri, S., Cunha, C., D\u2019Alessandro, T., Sandri, M., Russo, A., Giavaresi, G., Marcacci, M., Hung, C.T., and Tampieri, A. (2012). Magnetic hydroxyapatite bone substitutes to enhance tissue regeneration: Evaluation in vitro using osteoblast-like cells and in vivo in a bone defect. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0038710"},{"key":"ref_250","doi-asserted-by":"crossref","unstructured":"Tavares, F.J.T.M., Soares, P.I.P., Silva, J.C., and Borges, J.P. (2023). Preparation and in vitro characterization of magnetic CS\/PVA\/HA\/pSPIONs scaffolds for magnetic hyperthermia and bone regeneration. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24021128"},{"key":"ref_251","doi-asserted-by":"crossref","unstructured":"Maglio, M., Sartori, M., Gambardella, A., Shelyakova, T., Dediu, V.A., Santin, M., Pi\u00f1eiro, Y., L\u00f3pez, M.B., Rivas, J., and Tampieri, A. (2023). Bone regeneration guided by a magnetized scaffold in an ovine defect model. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24010747"},{"key":"ref_252","doi-asserted-by":"crossref","unstructured":"Petretta, M., Gambardella, A., Desando, G., Cavallo, C., Bartolotti, I., Shelyakova, T., Goranov, V., Brucale, M., Dediu, V.A., and Fini, M. (2021). Multifunctional 3D-Printed Magnetic Polycaprolactone\/Hydroxyapatite Scaffolds for Bone Tissue Engineering. Polymers, 13.","DOI":"10.3390\/polym13213825"},{"key":"ref_253","doi-asserted-by":"crossref","first-page":"8782","DOI":"10.1039\/C5TB01440A","article-title":"Good hydration and cell-biological performances of superparamagnetic calcium phosphate cement with concentration-dependent osteogenesis and angiogenesis induced by ferric iron","volume":"3","author":"Zhang","year":"2015","journal-title":"J. Mater. Chem. B"},{"key":"ref_254","doi-asserted-by":"crossref","unstructured":"Russo, T., Peluso, V., Gloria, A., Oliviero, O., Rinaldi, L., Improta, G., De Santis, R., and D\u2019Ant\u00f2, V. (2020). Combination design of time-dependent magnetic field and magnetic nanocomposites to guide cell behavior. Nanomaterials, 10.","DOI":"10.3390\/nano10030577"},{"key":"ref_255","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.msec.2017.03.258","article-title":"New bioactive bone-like microspheres with intrinsic magnetic properties obtained by bio-inspired mineralisation process","volume":"77","author":"Panseri","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_256","first-page":"111410","article-title":"Bio-inspired polymeric iron-doped hydroxyapatite microspheres as a tunable carrier of rhBMP-2","volume":"119","author":"Mumcuoglu","year":"2020","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_257","doi-asserted-by":"crossref","first-page":"20120833","DOI":"10.1098\/rsif.2012.0833","article-title":"Magnetic poly (\u03b5-caprolactone)\/iron-doped hydroxyapatite nanocomposite substrates for advanced bone tissue engineering","volume":"10","author":"Gloria","year":"2013","journal-title":"J. R. Soc. Interface"},{"key":"ref_258","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1002\/app.34771","article-title":"A basic approach toward the development of nanocomposite magnetic scaffolds for advanced bone tissue engineering","volume":"122","author":"Gloria","year":"2011","journal-title":"J. Appl. Polym. Sci."},{"key":"ref_259","doi-asserted-by":"crossref","first-page":"e2000318","DOI":"10.1002\/adhm.202000318","article-title":"A Magnetic Iron Oxide\/Polydopamine Coating Can Improve Osteogenesis of 3D-Printed Porous Titanium Scaffolds with a Static Magnetic Field by Upregulating the TGF\u03b2-Smads Pathway","volume":"9","author":"Huang","year":"2020","journal-title":"Adv. Health Mater."},{"key":"ref_260","doi-asserted-by":"crossref","first-page":"172033","DOI":"10.1098\/rsos.172033","article-title":"Enhanced in vitro biocompatibility and osteogenesis of titanium substrates immobilized with dopamine-assisted superparamagnetic Fe3O4 nanoparticles for hBMSCs","volume":"5","author":"Huang","year":"2018","journal-title":"R. Soc. Open Sci."},{"key":"ref_261","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1039\/C5TB00062A","article-title":"Biocompatibility and osteogenic capacity of borosilicate bioactive glass scaffolds loaded with Fe3O4 magnetic nanoparticles","volume":"3","author":"Wang","year":"2015","journal-title":"J. Mater. Chem. B"},{"key":"ref_262","doi-asserted-by":"crossref","unstructured":"Dittler, M.L., Zel\u00eds, P.M., Beltr\u00e1n, A.M., Destch, R., Grillo, C.A., Gonzalez, M.C., and Boccaccini, A.R. (2021). Magnetic 3D scaffolds for tissue engineering applications: Bioactive glass (45S5) coated with iron-loaded hydroxyapatite nanoparticles. Biomed. Mater., 16.","DOI":"10.1088\/1748-605X\/ac14cc"},{"key":"ref_263","doi-asserted-by":"crossref","unstructured":"Tang, B., Shen, X., Yang, Y., Xu, Z., Yi, J., Yao, Y., Cao, M., Zhang, Y., and Xia, H. (2021). Enhanced cellular osteogenic differentiation on CoFe2O4\/P (VDF-TrFE) nanocomposite coatings under static magnetic field. Colloids Surf. B Biointerfaces, 198.","DOI":"10.1016\/j.colsurfb.2020.111473"},{"key":"ref_264","doi-asserted-by":"crossref","first-page":"6446","DOI":"10.1021\/acsbiomaterials.9b00833","article-title":"Periodic-mechanical-stimulus enhanced osteogenic differentiation of mesenchymal stem cells on Fe3O4\/mineralized collagen coatings","volume":"5","author":"Lin","year":"2019","journal-title":"ACS Biomater. Sci. Eng."},{"key":"ref_265","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.actbio.2018.03.009","article-title":"Magnetically actuated mechanical stimuli on Fe3O4\/mineralized collagen coatings to enhance osteogenic differentiation of the MC3T3-E1 cells","volume":"71","author":"Zhuang","year":"2018","journal-title":"Acta Biomater."},{"key":"ref_266","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1039\/C7BM00061H","article-title":"Magnetic field application or mechanical stimulation via magnetic microparticles does not enhance chondrogenesis in mesenchymal stem cell sheets","volume":"5","author":"Dikina","year":"2017","journal-title":"Biomater. Sci."},{"key":"ref_267","doi-asserted-by":"crossref","first-page":"23423","DOI":"10.1039\/C9NR07170A","article-title":"Synergistic osteogenesis promoted by magnetically actuated nano-mechanical stimuli","volume":"11","author":"Hao","year":"2019","journal-title":"Nanoscale"},{"key":"ref_268","doi-asserted-by":"crossref","first-page":"19976","DOI":"10.1021\/acsami.3c01139","article-title":"Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis","volume":"15","author":"Yu","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_269","doi-asserted-by":"crossref","first-page":"19276","DOI":"10.3390\/ijms140919276","article-title":"Receptor-Targeted, Magneto-Mechanical Stimulation of Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells","volume":"14","author":"Hu","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"ref_270","doi-asserted-by":"crossref","first-page":"21690","DOI":"10.1021\/acsnano.3c06909","article-title":"Sophisticated magneto-mechanical actuation promotes in situ stem cell assembly and chondrogenesis for treating osteoarthritis","volume":"17","author":"Deng","year":"2023","journal-title":"ACS Nano"},{"key":"ref_271","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1002\/adhm.201400835","article-title":"Physical Stimuli-Induced Chondrogenic Differentiation of Mesenchymal Stem Cells Using Magnetic Nanoparticles","volume":"4","author":"Son","year":"2015","journal-title":"Adv. Healthc. Mater."},{"key":"ref_272","doi-asserted-by":"crossref","first-page":"19214","DOI":"10.1007\/s11356-019-07231-2","article-title":"Magnetic nanoparticles for hyperthermia in cancer treatment: An emerging tool","volume":"27","author":"Jose","year":"2019","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref_273","doi-asserted-by":"crossref","unstructured":"Manjusha, V., Rajeev, M., and Anirudhan, T. (2023). Magnetic nanoparticle embedded chitosan-based polymeric network for the hydrophobic drug delivery of paclitaxel. Int. J. Biol. Macromol., 235.","DOI":"10.1016\/j.ijbiomac.2023.123900"},{"key":"ref_274","doi-asserted-by":"crossref","unstructured":"Paltanea, G., Paltanea, V.M., Antoniac, I., Antoniac, A., Nemoianu, I.V., Robu, A., and Dura, H. (2023). A Review of Biomimetic and Biodegradable Magnetic Scaffolds for Bone Tissue Engineering and Oncology. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24054312"},{"key":"ref_275","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1016\/j.nano.2018.06.002","article-title":"Effects of static magnetic fields on natural or magnetized mesenchymal stromal cells: Repercussions for magnetic targeting","volume":"14","author":"Silva","year":"2018","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"ref_276","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1166\/jbn.2016.2248","article-title":"Magnetic Labelling of Mesenchymal Stem Cells with Iron-Doped Hydroxyapatite Nanoparticles as Tool for Cell Therapy","volume":"12","author":"Panseri","year":"2016","journal-title":"J. Biomed. Nanotechnol."},{"key":"ref_277","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1186\/s13287-023-03426-0","article-title":"A review on the effect of nanocomposite scaffolds reinforced with magnetic nanoparticles in osteogenesis and healing of bone injuries","volume":"14","author":"Sadeghzadeh","year":"2023","journal-title":"Stem Cell Res. Ther."},{"key":"ref_278","doi-asserted-by":"crossref","unstructured":"Carvalho, T.S.S., Torres, P.M.C., Belo, J.H., Mano, J., and Olhero, S.M. (2023). Bioactive Magnetic Materials in Bone Tissue Engineering: A Review of Recent Findings in CaP-Based Particles and 3D-Printed Scaffolds. Adv. NanoBiomed Res., 3.","DOI":"10.1002\/anbr.202300035"},{"key":"ref_279","doi-asserted-by":"crossref","first-page":"124166","DOI":"10.1016\/j.cej.2020.124166","article-title":"Mineralization of ytterbium-doped hydroxyapatite nanorod arrays in magnetic chitosan scaffolds improves osteogenic and angiogenic abilities for bone defect healing","volume":"387","author":"Tang","year":"2020","journal-title":"Chem. Eng. J."},{"key":"ref_280","doi-asserted-by":"crossref","unstructured":"Cojocaru, F.-D., Balan, V., and Verestiuc, L. (2022). Advanced 3D Magnetic Scaffolds for Tumor-Related Bone Defects. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms232416190"},{"key":"ref_281","doi-asserted-by":"crossref","first-page":"083001","DOI":"10.1149\/2162-8777\/ace994","article-title":"Magnetic and dielectric properties of hybrid nanocomposites of biologically extracted hydroxyapatite\/hematite\/silicon dioxide for potential use in bone replacement applications","volume":"12","author":"Alturky","year":"2023","journal-title":"ECS J. Solid State Sci. Technol."},{"key":"ref_282","doi-asserted-by":"crossref","first-page":"112544","DOI":"10.1016\/j.micromeso.2023.112544","article-title":"Surface PEGylation of ZIF-8 metal-organic framework based on magnetic hydroxyapatite as a pH\/magnetic targeting responsive system for anticancer drug delivery","volume":"354","author":"Zeyni","year":"2023","journal-title":"Microporous Mesoporous Mater."},{"key":"ref_283","doi-asserted-by":"crossref","first-page":"104404","DOI":"10.1016\/j.arabjc.2022.104404","article-title":"Introducing a new pharmaceutical agent: Facile synthesis of CuFe12O19@HAp-APTES magnetic nanocomposites and its cytotoxic effect on HEK-293 cell as an efficient in vitro drug delivery system for atenolol","volume":"16","author":"Naseri","year":"2023","journal-title":"Arab. J. Chem."},{"key":"ref_284","doi-asserted-by":"crossref","first-page":"e2300430","DOI":"10.1002\/smll.202300430","article-title":"Magnetic Microsphere Scaffold-Based Soft Microbots for Targeted Mesenchymal Stem Cell Delivery","volume":"19","author":"Tian","year":"2023","journal-title":"Small"},{"key":"ref_285","doi-asserted-by":"crossref","first-page":"4632","DOI":"10.1021\/acs.molpharmaceut.8b00626","article-title":"Optimization of Deformable Magnetic-Sensitive Hydrogel-Based Targeting System in Suspension Fluid for Site-Specific Drug Delivery","volume":"15","author":"Liu","year":"2018","journal-title":"Mol. Pharm."},{"key":"ref_286","doi-asserted-by":"crossref","first-page":"109269","DOI":"10.1016\/j.matdes.2020.109269","article-title":"Magnetic hydroxyapatite nanocomposites: The advances from synthesis to biomedical applications","volume":"197","author":"Mushtaq","year":"2021","journal-title":"Mater. Des."},{"key":"ref_287","doi-asserted-by":"crossref","first-page":"8389","DOI":"10.2147\/IJN.S147355","article-title":"Magnetic hydroxyapatite: A promising multifunctional platform for nanomedicine application","volume":"12","author":"Mondal","year":"2017","journal-title":"Int. J. Nanomed."},{"key":"ref_288","doi-asserted-by":"crossref","first-page":"20180236","DOI":"10.1098\/rsif.2018.0236","article-title":"A combined low-frequency electromagnetic and fluidic stimulation for a controlled drug release from superparamagnetic calcium phosphate nanoparticles: Potential application for cardiovascular diseases","volume":"15","author":"Marrella","year":"2018","journal-title":"J. R. Soc. Interface"},{"key":"ref_289","first-page":"258","article-title":"Cancer and concerns","volume":"3","author":"Davar","year":"2023","journal-title":"Doctmedico J."},{"key":"ref_290","doi-asserted-by":"crossref","unstructured":"Lara-Ochoa, S., Ortega-Lara, W., and Guerrero-Beltr\u00e1n, C.E. (2021). Hydroxyapatite Nanoparticles in Drug Delivery: Physicochemistry and Applications. Pharmaceutics, 13.","DOI":"10.3390\/pharmaceutics13101642"},{"key":"ref_291","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.msec.2016.07.028","article-title":"In situ microemulsion synthesis of hydroxyapatite-MgFe2O4 nanocomposite as a magnetic drug delivery system","volume":"68","author":"Foroughi","year":"2016","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_292","doi-asserted-by":"crossref","first-page":"144215","DOI":"10.1016\/j.apsusc.2019.144215","article-title":"Synthesis of one-dimensional magnetite hydroxyapatite nanorods on reduced graphene oxide sheets for selective separation and controlled delivery of hemoglobin","volume":"501","author":"Bharath","year":"2020","journal-title":"Appl. Surf. Sci."},{"key":"ref_293","doi-asserted-by":"crossref","unstructured":"Jiang, W., Wang, Q., Cui, D., Han, L., Chen, L., Xu, J., and Niu, N. (2023). Metal-polyphenol network coated magnetic hydroxyapatite for pH-activated MR imaging and drug delivery. Colloids Surf. B Biointerfaces, 222.","DOI":"10.1016\/j.colsurfb.2022.113076"},{"key":"ref_294","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1039\/C5TB01524C","article-title":"Superparamagnetic iron-doped nanocrystalline apatite as a delivery system for doxorubicin","volume":"4","author":"Iafisco","year":"2015","journal-title":"J. Mater. Chem. B"},{"key":"ref_295","doi-asserted-by":"crossref","unstructured":"Pusta, A., Tertis, M., Cr\u0103ciunescu, I., Turcu, R., Mirel, S., and Cristea, C. (2023). Recent Advances in the Development of Drug Delivery Applications of Magnetic Nanomaterials. Pharmaceutics, 15.","DOI":"10.3390\/pharmaceutics15071872"},{"key":"ref_296","doi-asserted-by":"crossref","first-page":"025145","DOI":"10.1063\/9.0000558","article-title":"Ultra-short pulse magnetic fields on effective magnetic hyperthermia for cancer therapy","volume":"13","author":"Kuwahata","year":"2023","journal-title":"AIP Adv."},{"key":"ref_297","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.2147\/IJN.S375964","article-title":"How Magnetic Composites are Effective Anticancer Therapeutics? A Comprehensive Review of the Literature","volume":"18","author":"Yusefi","year":"2023","journal-title":"Int. J. Nanomed."},{"key":"ref_298","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1109\/JERM.2018.2866345","article-title":"Numerical investigation of bone tumor hyperthermia treatment using magnetic scaffolds","volume":"2","author":"Fanti","year":"2018","journal-title":"IEEE J. Electromagn. RF Microw. Med. Biol."},{"key":"ref_299","doi-asserted-by":"crossref","first-page":"127677","DOI":"10.1016\/j.matchemphys.2023.127677","article-title":"Biocompatible polymer functionalized magnetic nanoparticles for antimicrobial and anticancer activities","volume":"301","author":"Munir","year":"2023","journal-title":"Mater. Chem. Phys."},{"key":"ref_300","doi-asserted-by":"crossref","first-page":"13683","DOI":"10.1039\/D3RA01180A","article-title":"Ag NPs decorated on the magnetic rod-like hydroxyapatite\/MIL-101(Fe) nanocomposite as an efficient catalyst for the reduction of some nitroaromatic compounds and as an effective antimicrobial agent","volume":"13","author":"Beiranvand","year":"2023","journal-title":"RSC Adv."},{"key":"ref_301","doi-asserted-by":"crossref","first-page":"5839","DOI":"10.1021\/acsabm.1c00440","article-title":"Magnetic Nanoparticles for Biomedical Applications: From the Soul of the Earth to the Deep History of Ourselves","volume":"4","author":"Martins","year":"2021","journal-title":"ACS Appl. Bio Mater."},{"key":"ref_302","doi-asserted-by":"crossref","unstructured":"Bealer, E.J., Kavetsky, K., Dutko, S., Lofland, S., and Hu, X. (2019). Protein and Polysaccharide-Based Magnetic Composite Materials for Medical Applications. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21010186"},{"key":"ref_303","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.msec.2019.03.066","article-title":"Mesoporous superparamagnetic hydroxyapatite nanocomposite: A multifunctional platform for synergistic targeted chemo-magnetotherapy","volume":"101","author":"Izadi","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_304","doi-asserted-by":"crossref","unstructured":"Katundi, D., Bayraktar, E., Gatamorta, F., and Miskioglu, I. (2019). Design of hydroxyapatite\/magnetite (HAP\/Fe3O4) based composites reinforced with ZnO and MgO for biomedical applications. Biomed. J. Sci. Tech. Res., 21.","DOI":"10.26717\/BJSTR.2019.21.003585"},{"key":"ref_305","doi-asserted-by":"crossref","first-page":"2226845","DOI":"10.1080\/02656736.2023.2226845","article-title":"Mild magnetic hyperthermia is synergistic with an antibiotic treatment against dual species biofilms consisting of S. aureus and P. aeruginosa by enhancing metabolic activity","volume":"40","author":"Almutairi","year":"2023","journal-title":"Int. J. Hyperth."}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/25\/5\/2809\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:06:42Z","timestamp":1760105202000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/25\/5\/2809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,28]]},"references-count":305,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,3]]}},"alternative-id":["ijms25052809"],"URL":"https:\/\/doi.org\/10.3390\/ijms25052809","relation":{},"ISSN":["1422-0067"],"issn-type":[{"value":"1422-0067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,28]]}}}