{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:36:59Z","timestamp":1782603419360,"version":"3.54.5"},"reference-count":55,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,4,14]],"date-time":"2024-04-14T00:00:00Z","timestamp":1713052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Chronic odontogenic maxillary sinusitis (COMS), a prolonged inflammation of the maxillary sinus lasting over 12 weeks, is often a result of periapical lesions, marginal periodontitis, and complications like oro-antral communication (OAC) and fistula (OAF). OAC, commonly emerging post-teeth extraction in the lateral maxilla, lacks documented treatments using advanced platelet-rich fibrin (A-PRF). This study evaluates A-PRF\u2019s efficacy in treating COMS and immediately sealing extensive OAC. A case of a 28-year-old male with COMS linked to a periapical lesion and supernumerary molars is presented. Treatment involved extracting specific teeth while preserving adjacent ones and using A-PRF for immediate OAC closure. A-PRF, enriched with growth factors, was pivotal in healing, showcasing enhanced tissue regeneration, pain reduction, and faster recovery. The findings suggest A-PRF as an effective adjunct in treating extensive OAC and COMS, proposing its inclusion in standard treatment protocols. This study underscores A-PRF\u2019s potential in improving outcomes for patients with COMS and related complications.<\/jats:p>","DOI":"10.3390\/ijms25084339","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T10:24:26Z","timestamp":1713176666000},"page":"4339","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Treatment of Odontogenic Maxillary Sinusitis with the Use of Growth Factors in Advanced Platelet-Rich Fibrin for Immediate Closure of Oro-Antral Communication: A Case Report"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0514-4997","authenticated-orcid":false,"given":"Paulina","family":"Adamska","sequence":"first","affiliation":[{"name":"Division of Oral Surgery, Faculty of Medicine, Medical University of Gda\u0144sk, 7 D\u0119binki Street, 80-210 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"Pyli\u0144ska-D\u0105browska","sequence":"additional","affiliation":[{"name":"Department of Dental Prosthetics, Faculty of Medicine, Medical University of Gda\u0144sk, 18 Orzeszkowej Street, 80-204 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5112-6322","authenticated-orcid":false,"given":"Marcin","family":"Stasiak","sequence":"additional","affiliation":[{"name":"Division of Orthodontics, Faculty of Medicine, Medical University of Gda\u0144sk, Aleja Zwyci\u0119stwa 42c, 80-210 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4494-122X","authenticated-orcid":false,"given":"Magdalena","family":"Kaczoruk-Wieremczuk","sequence":"additional","affiliation":[{"name":"Individual Specialist Oral Surgery Practice Magdalena Kaczoruk-Wieremczuk, 41\/31 W\u0142adys\u0142awa Wysockiego Street, 17-100 Bielsk Podlaski, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6021-2855","authenticated-orcid":false,"given":"Ewa","family":"Koz\u0142owska","sequence":"additional","affiliation":[{"name":"Institute of Manufacturing and Materials Technology, Faculty of Mechanical Engineering and Ship Technology, Gda\u0144sk University of Technology, 11\/12 Gabriela Narutowicza Street, 80-233 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Zedler","sequence":"additional","affiliation":[{"name":"Division of Oral Surgery, Faculty of Medicine, Medical University of Gda\u0144sk, 7 D\u0119binki Street, 80-210 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"Studniarek","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine, Medical University of Gda\u0144sk, 17 Smoluchowskiego Street, 80-210 Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,14]]},"reference":[{"key":"ref_1","first-page":"2357","article-title":"Regenerative Potential of Platelet\u2014Rich Fibrin in Maxillary Sinus Floor Lift Techniques: A Systematic Review","volume":"37","author":"Gerardi","year":"2023","journal-title":"J. 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