{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T19:16:00Z","timestamp":1791573360457,"version":"4.3.4"},"reference-count":132,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>This editorial investigates chronic traumatic encephalopathy (CTE) as a course of Alzheimer\u2019s disease (AD). CTE is a debilitating neurodegenerative disease that is the result of repeated mild traumatic brain injury (TBI). Many epidemiological studies show that experiencing a TBI in early or middle life is associated with an increased risk of dementia later in life. Chronic traumatic encephalopathy (CTE) and Alzheimer\u2019s disease (AD) present a series of similar neuropathological features that were investigated in this work like recombinant tau into filaments or the accumulation and aggregation of A\u03b2 protein. However, these two conditions differ from each other in brain\u2013blood barrier damage. The purpose of this review was to evaluate information about CTE and AD from various articles, focusing especially on new therapeutic possibilities for the improvement in cognitive skills.<\/jats:p>","DOI":"10.3390\/ijms25094639","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T10:18:36Z","timestamp":1713953916000},"page":"4639","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Chronic Traumatic Encephalopathy as the Course of Alzheimer\u2019s Disease"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4068-4772","authenticated-orcid":false,"given":"Magdalena","family":"Pszczo\u0142owska","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Wroclaw Medical University, Ludwika Pasteura 1, 50-367 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Walczak","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Wroclaw Medical University, Ludwika Pasteura 1, 50-367 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2648-7214","authenticated-orcid":false,"given":"Weronika","family":"Mi\u015bk\u00f3w","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Wroclaw Medical University, Ludwika Pasteura 1, 50-367 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5026-0344","authenticated-orcid":false,"given":"Katarzyna","family":"Antosz","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Wroclaw Medical University, Ludwika Pasteura 1, 50-367 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9185-038X","authenticated-orcid":false,"given":"Joanna","family":"Batko","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Wroclaw Medical University, Ludwika Pasteura 1, 50-367 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donata","family":"Kurpas","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Wroclaw Medical University, Ul. Kazimierza Bartla 5, 51-618 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"Leszek","sequence":"additional","affiliation":[{"name":"Clinic of Psychiatry, Department of Psychiatry, Wroclaw Medical University, Ludwika Pasteura 10, 50-367 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"713","DOI":"10.3389\/fneur.2019.00713","article-title":"Chronic Traumatic Encephalopathy: A Brief Overview","volume":"10","year":"2019","journal-title":"Front. Neurol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1001\/archneurol.2011.3747","article-title":"Dementia Resulting from Traumatic Brain Injury","volume":"69","author":"Shively","year":"2012","journal-title":"Arch. 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