{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T21:01:21Z","timestamp":1780434081259,"version":"3.54.1"},"reference-count":14,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministerului Educa\u021biei, prin Agen\u021bia de Credite \u0219i Burse de Studii","award":["5686\/25.08.2023"],"award-info":[{"award-number":["5686\/25.08.2023"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Bordetella hinzii (B. hinzii), a Gram-negative bacillus commonly associated with respiratory infections in animals, has garnered attention for its sporadic cases in humans, particularly in immunocompromised individuals. Despite its opportunistic nature, there remains limited understanding regarding its pathogenicity, diagnostic challenges, and optimal treatment strategies, especially in the context of immunosuppression. Herein, we present the first documented case of acute bronchitis caused by B. hinzii in an immunocompromised patient following double-lung transplantation. The patient, a former smoker with sarcoidosis stage IV, underwent transplant surgery and subsequently developed a febrile episode, leading to the identification of B. hinzii in broncho-alveolar lavage samples. Antimicrobial susceptibility testing revealed resistance to multiple antibiotics, necessitating tailored treatment adjustments. Our case underscores the importance of heightened awareness among clinicians regarding B. hinzii infections and the imperative for further research to elucidate its epidemiology and optimal management strategies, particularly in immunocompromised populations.<\/jats:p>","DOI":"10.3390\/ijms25094708","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T05:13:41Z","timestamp":1714108421000},"page":"4708","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Uncovering the Unseen: Bordetella hinzii Emerges in a Lung Transplant Recipient"],"prefix":"10.3390","volume":"25","author":[{"given":"Damiana-Maria","family":"Vulturar","sequence":"first","affiliation":[{"name":"Pneumology and Lung Transplantation Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"},{"name":"Department of Pneumology, Iuliu Hatieganu University of Medicine and Pharmacy, 400332 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Pilmis","sequence":"additional","affiliation":[{"name":"Mobile Clinical Microbiology Team, Paris Saint-Joseph Hospital Group, 75014 Paris, France"},{"name":"UMR_1319, Micalis Institute, Paris-Saclay University, INRAe, AgroParisTech, 92290 Ch\u00e2tenay-Malabry, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Rouzaud","sequence":"additional","affiliation":[{"name":"Mobile Clinical Microbiology Team, Paris Saint-Joseph Hospital Group, 75014 Paris, France"},{"name":"Necker Pasteur Centre for Infectious Diseases and Tropical Medicine, IHU Imagine, Necker Enfants Malades, University Hospital, 75015 Paris, France"},{"name":"Institut Pasteur, Universit\u00e9 Paris Cit\u00e9, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Gigandon","sequence":"additional","affiliation":[{"name":"Microbiology Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga\u00eblle","family":"Dauriat","sequence":"additional","affiliation":[{"name":"Pneumology and Lung Transplantation Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9verine","family":"Feuillet-Soummer","sequence":"additional","affiliation":[{"name":"Pneumology and Lung Transplantation Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9808-6013","authenticated-orcid":false,"given":"Liviu-Stefan","family":"Moaca","sequence":"additional","affiliation":[{"name":"Pneumology and Lung Transplantation Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elie","family":"Fadel","sequence":"additional","affiliation":[{"name":"Pneumology and Lung Transplantation Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"},{"name":"UMR_1319, Micalis Institute, Paris-Saclay University, INRAe, AgroParisTech, 92290 Ch\u00e2tenay-Malabry, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4760-6267","authenticated-orcid":false,"given":"Olaf","family":"Mercier","sequence":"additional","affiliation":[{"name":"Pneumology and Lung Transplantation Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"},{"name":"UMR_1319, Micalis Institute, Paris-Saclay University, INRAe, AgroParisTech, 92290 Ch\u00e2tenay-Malabry, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Fabre","sequence":"additional","affiliation":[{"name":"Pneumology and Lung Transplantation Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"},{"name":"UMR_1319, Micalis Institute, Paris-Saclay University, INRAe, AgroParisTech, 92290 Ch\u00e2tenay-Malabry, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Lortholary","sequence":"additional","affiliation":[{"name":"Necker Pasteur Centre for Infectious Diseases and Tropical Medicine, IHU Imagine, Necker Enfants Malades, University Hospital, 75015 Paris, France"},{"name":"Institut Pasteur, Universit\u00e9 Paris Cit\u00e9, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Le Pavec","sequence":"additional","affiliation":[{"name":"Pneumology and Lung Transplantation Department, Marie-Lannelongue\u2013Saint Joseph Hospital Group, 92350 Le Plessis-Robinson, France"},{"name":"UMR_1319, Micalis Institute, Paris-Saclay University, INRAe, AgroParisTech, 92290 Ch\u00e2tenay-Malabry, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5452","DOI":"10.1099\/ijsem.0.001540","article-title":"Identification and Taxonomic Characterization of Bordetella pseudohinzii Sp. 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