{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:27:40Z","timestamp":1776410860461,"version":"3.51.2"},"reference-count":50,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T00:00:00Z","timestamp":1724457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University Grant Commission (UGC), New Delhi, India","award":["2021R1I1A1A01057742"],"award-info":[{"award-number":["2021R1I1A1A01057742"]}]},{"name":"University Grant Commission (UGC), New Delhi, India","award":["2022R1A2C2091029"],"award-info":[{"award-number":["2022R1A2C2091029"]}]},{"name":"University Grant Commission (UGC), New Delhi, India","award":["VMRF\/Research\/SeedMoney\/AY2023-24\/AVMC\/1"],"award-info":[{"award-number":["VMRF\/Research\/SeedMoney\/AY2023-24\/AVMC\/1"]}]},{"name":"National Research Foundation of Korea","award":["2021R1I1A1A01057742"],"award-info":[{"award-number":["2021R1I1A1A01057742"]}]},{"name":"National Research Foundation of Korea","award":["2022R1A2C2091029"],"award-info":[{"award-number":["2022R1A2C2091029"]}]},{"name":"National Research Foundation of Korea","award":["VMRF\/Research\/SeedMoney\/AY2023-24\/AVMC\/1"],"award-info":[{"award-number":["VMRF\/Research\/SeedMoney\/AY2023-24\/AVMC\/1"]}]},{"name":"Seed Money Grant, Vinayaka Missions Research Foundation, India","award":["2021R1I1A1A01057742"],"award-info":[{"award-number":["2021R1I1A1A01057742"]}]},{"name":"Seed Money Grant, Vinayaka Missions Research Foundation, India","award":["2022R1A2C2091029"],"award-info":[{"award-number":["2022R1A2C2091029"]}]},{"name":"Seed Money Grant, Vinayaka Missions Research Foundation, India","award":["VMRF\/Research\/SeedMoney\/AY2023-24\/AVMC\/1"],"award-info":[{"award-number":["VMRF\/Research\/SeedMoney\/AY2023-24\/AVMC\/1"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Chitosan-based biomaterials are being investigated for their unique properties that support skin regeneration and wound healing. This study focused on the preparation and characterization of a mupirocin (Mup)-loaded PEGylated chitosan (CS-PEG) nanoparticulate film (NF) [CBNF]. The CBNF was characterized using FTIR spectroscopy and SEM analysis. The results demonstrated that CBNF was successfully incorporated into the composites, as shown by functional group modification through FTIR analysis. Additionally, the SEM micrograph revealed the deposition of nanoparticles (&lt;200 nm) on the surface of transparent CBNF. The film has higher water absorption (\u22651700%) and moderate water retention ability within 6 h. Furthermore, histological findings showed significant development, with re-epithelialization and granulation of tissues after 19 days, indicating the healing efficiency of CNBF. These results suggest that drug-loaded films could be an effective carrier and delivery agent for Mup-like anti-inflammatory drugs.<\/jats:p>","DOI":"10.3390\/ijms25179188","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T05:16:24Z","timestamp":1724649384000},"page":"9188","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Fabrication of Mupirocin-Loaded PEGylated Chitosan Nanoparticulate Films for Enhanced Wound Healing"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7186-6926","authenticated-orcid":false,"given":"Shajahan","family":"Azeez","sequence":"first","affiliation":[{"name":"Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai 600025, India"},{"name":"Department of Medical Biotechnology, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission\u2019s Research Foundation (DU), Puducherry Campus, Puducherry 607402, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8142-0063","authenticated-orcid":false,"given":"Anbazhagan","family":"Sathiyaseelan","sequence":"additional","affiliation":[{"name":"Department of Bio-Health Convergence, Kangwon National University, Chuncheon 24341, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaviyarasan","family":"Venkatesan","sequence":"additional","affiliation":[{"name":"Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai 600025, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1760-1622","authenticated-orcid":false,"given":"Myeong-Hyeon","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Bio-Health Convergence, Kangwon National University, Chuncheon 24341, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s42114-023-00764-8","article-title":"Directional transport of drug droplets based on structural and wettability gradients on antibacterial janus wound plaster with hemostatic, antiextravasation, and prehealing properties","volume":"6","author":"Lin","year":"2023","journal-title":"Adv. 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