{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:53:27Z","timestamp":1788540807999,"version":"build-2803163510"},"reference-count":89,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"N.K.U.A. Special Account for Research Grants"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Selenium-binding proteins (SBPs) represent a ubiquitous and conserved protein family with yet unclear biochemical and molecular functions. The importance of the human homolog has been extensively studied as it is implicated in many cancer types and other diseases. On the other hand, little is known regarding plant homologs. In plants, there is evidence that SBP participates in developmental procedures, oxidative stress responses, selenium and cadmium binding, and pathogenic tolerance. Moreover, recent studies have revealed that SBP is a methanethiol oxidase (MTO) catalyzing the conversion of methanethiol into formaldehyde, H2S, and H2O2. The two later products emerge as key signal molecules, playing pivotal roles in physiological processes and environmental stress responses. In this review, we highlight the available information regarding plants in order to introduce and emphasize the importance of SBP1 and its role in plant growth, development, and abiotic\/biotic stress.<\/jats:p>","DOI":"10.3390\/ijms25179372","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T11:12:13Z","timestamp":1724929933000},"page":"9372","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Selenium-Binding Protein 1 (SBP1): A New Putative Player of Stress Sensing in Plants"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3830-3085","authenticated-orcid":false,"given":"Irene","family":"Dervisi","sequence":"first","affiliation":[{"name":"Department of Botany, Faculty of Biology, National & Kapodistrian University of Athens, 15784 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3873-5304","authenticated-orcid":false,"given":"Aikaterini","family":"Koletti","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 11855 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3918-6355","authenticated-orcid":false,"given":"Adamantia","family":"Agalou","sequence":"additional","affiliation":[{"name":"Laboratory of Toxicological Control of Pesticides, Scientific Directorate of Pesticides\u2019 Control & Phytopharmacy, Benaki Phytopathological Institute (BPI), 14561 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7717-2981","authenticated-orcid":false,"given":"Kosmas","family":"Haralampidis","sequence":"additional","affiliation":[{"name":"Department of Botany, Faculty of Biology, National & Kapodistrian University of Athens, 15784 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanouil","family":"Flemetakis","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 11855 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2346-7132","authenticated-orcid":false,"given":"Andreas","family":"Roussis","sequence":"additional","affiliation":[{"name":"Department of Botany, Faculty of Biology, National & Kapodistrian University of Athens, 15784 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.1021\/ja01569a087","article-title":"Selenium as an Integral Part of Factor 3 against Dietary Necrotic Liver Degeneration","volume":"79","author":"Schwarz","year":"1957","journal-title":"J. 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