{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T01:06:59Z","timestamp":1762391219346,"version":"build-2065373602"},"reference-count":54,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Jilin Province science and technology development plan project","award":["20240303086NC"],"award-info":[{"award-number":["20240303086NC"]}]},{"name":"National College Students Innovation and Entrepreneurship Project in China","award":["20240303086NC"],"award-info":[{"award-number":["20240303086NC"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Straw, a predominant agricultural residue, represents a significant waste product. Harnessing its potential is of paramount importance both in terms of research and economic value. In this study, chemically pretreated corn straw was infused with distinct microbial fungal mycelium variants and subsequently transformed into a series of biochars through a process involving carbonization and activation. The findings revealed enhancements in the specific surface area and total pore volume of mycelium-doped straw biochars compared to the original corn straw biochar (BCS). Additionally, discernible disparities were observed in their physical and chemical attributes, encompassing functional groups, surface chemistry, and micro-morphology. Notably, in water-based antibiotic removal experiments focusing on tetracycline hydrochloride (TH) and chloramphenicol (CP), the mycelium-doped straw biochars outperformed BCS. Their maximum adsorption capacities for TH and CP surpassed those of alternative adsorbents, including other biochars. Impressively, even after five cycles, the biochar exhibited a removal rate exceeding 80%, attesting to its robust stability. This study successfully emphasized the efficacy of incorporating fungal mycelium to enhance the adsorption properties of straw-based biochar, introducing a new theoretical basis for the development of lignocellulosic materials.<\/jats:p>","DOI":"10.3390\/ijms252111387","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T09:07:04Z","timestamp":1729674424000},"page":"11387","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Mycelium-Doped Straw Biochars for Antibiotic Control"],"prefix":"10.3390","volume":"25","author":[{"given":"Bolun","family":"Zhang","sequence":"first","affiliation":[{"name":"College of Life Sciences, Jilin Agricultural University, Changchun 130118, China"},{"name":"Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruqi","family":"Li","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Jilin Agricultural University, Changchun 130118, China"},{"name":"Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiji","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Jilin Agricultural University, Changchun 130118, China"},{"name":"Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Han","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Jilin Agricultural University, Changchun 130118, China"},{"name":"Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunzhe","family":"Jia","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Jilin Agricultural University, Changchun 130118, China"},{"name":"Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siji","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Jilin Agricultural University, Changchun 130118, China"},{"name":"Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxiao","family":"Yu","sequence":"additional","affiliation":[{"name":"College of Life Sciences, Jilin Agricultural University, Changchun 130118, China"},{"name":"Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, Ministry of Education, Jilin Agricultural University, Changchun 130118, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"D\u00edaz, L., Fuentes, R., R-D\u00edaz, J., Rodr\u00edguez, K.E., and Gonzalez, L.A. (2024). Enhancing sustainable energy production in the Canary Islands: Valorization of local biomass resources through thermochemical processes. Biomass Bioenergy, 188.","DOI":"10.1016\/j.biombioe.2024.107327"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Yu, X., Li, J., Sun, Y., Xie, Y., Su, Y., Tang, S., Bian, S., Liu, L., Huo, F., and Huang, Q. (2024). Co-immobilized multi-enzyme biocatalytic system on reversible and solublecarrier for saccharification of corn straw cellulose. Bioresour. Technol., 395.","DOI":"10.1016\/j.biortech.2024.130325"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Yu, X., Li, X., Jin, T., Su, Y., Li, J., Gao, M., Zheng, L., Tan, S., and Chen, G. (2020). Integrated biorefinery process for production of sophorolipids from corn straw. Biochem. Eng. J., 167.","DOI":"10.1016\/j.bej.2020.107908"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Shao, L., Chen, H., Li, Y., Li, J., Chen, G., and Wang, G. (2020). Pretreatment of corn stover via sodium hydroxide-urea solutions to improve the glucose yield. Bioresour. Technol., 307.","DOI":"10.1016\/j.biortech.2020.123191"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"129099","DOI":"10.1016\/j.seppur.2024.129099","article-title":"Biomass-derived functional materials: Preparation, functionalization, and applications in adsorption and catalytic separation of carbon dioxide and other atmospheric pollutants","volume":"354","author":"Kong","year":"2025","journal-title":"Sep. Purif. Technol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"103233","DOI":"10.1016\/j.eti.2023.103233","article-title":"Improvement of cow manure anaerobic digestion performance by three different crop straw biochars","volume":"31","author":"Liu","year":"2023","journal-title":"Environ. Technol. Innov."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"133992","DOI":"10.1016\/j.scitotenv.2023.166992","article-title":"Optimization of biogas production from straw wastes by differentpretreatments: Progress, challenges, and prospects","volume":"905","author":"Wang","year":"2023","journal-title":"Sci. Total. Environ."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Khan, M.F.S., Akbar, M., Xu, Z., and Wang, H. (2021). A review on the role of pretreatment technologies in the hydrolysis oflignocellulosic biomass of corn stover. Biomass Bioenergy, 155.","DOI":"10.1016\/j.biombioe.2021.106276"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"155662","DOI":"10.1016\/j.scitotenv.2022.155662","article-title":"Graphene oxide modified \u03ba-carrageenan\/sodium alginate double-network hydrogel for effective adsorption of antibiotics in a batch and fixed-bed column system","volume":"837","author":"Yang","year":"2022","journal-title":"Sci. Total. Environ."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.ijbiomac.2022.04.033","article-title":"Combining biological and chemical methods to disassemble of cellulose from corn straw for the preparation of porous carbons with enhanced adsorption performance","volume":"209","author":"Jin","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"124956","DOI":"10.1016\/j.jhazmat.2020.124956","article-title":"Disassembly of lignocellulose into cellulose, hemicellulose, and lignin for preparation of porous carbon materials with enhanced performances","volume":"408","author":"Chen","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"100412","DOI":"10.1016\/j.apsadv.2023.100412","article-title":"Impact of modification by red mud components on the sorption properties of activated carbon","volume":"16","author":"Kyrii","year":"2023","journal-title":"Appl. Surf. Sci. Adv."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"110136","DOI":"10.1016\/j.jece.2023.110136","article-title":"2023. Adsorption of lead ions by magnetic carbon: Comparison of magnetic carbon properties and modification methods","volume":"11","author":"Li","year":"2023","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"111258","DOI":"10.1016\/j.inoche.2023.111258","article-title":"The acid modified magnetic carbon quantum dots as a capable nano-catalyst for the synthesis of pyridines and pyrazoles","volume":"156","author":"Ghorbani","year":"2023","journal-title":"Inorg. Chem. Commun."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"109569","DOI":"10.1016\/j.foodhyd.2023.109569","article-title":"Multivalent cations modulating microstructure and interactions of potato protein and fungal hyphae in a functional meat analogue","volume":"149","author":"Yang","year":"2024","journal-title":"Food Hydrocoll."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"101659","DOI":"10.1016\/j.eti.2021.101659","article-title":"Preparation of biomass carbon material based on Fomes fomentarius via alkali activation and its application for the removal of brilliant green in wastewater","volume":"23","author":"Xia","year":"2021","journal-title":"Environ. Technol. Innov."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"5285","DOI":"10.1016\/j.cub.2022.11.009","article-title":"Fungal hyphae regulate bacterial diversity and plasmid-mediated functional novelty during range expansion","volume":"32","author":"Ruan","year":"2022","journal-title":"Curr. Biol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.ijbiomac.2022.02.014","article-title":"A novel lignin-based hierarchical porous carbon for efficient and selective removal of Cr(VI) from wastewater","volume":"204","author":"Liang","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"113218","DOI":"10.1016\/j.mcat.2023.113218","article-title":"Gradient porous biochar materials with high specific surface area as supports for Pd\/C catalysts for efficient maleic acid hydrogenation","volume":"545","author":"Dou","year":"2023","journal-title":"Mol. Catal."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"131962","DOI":"10.1016\/j.chemosphere.2021.131962","article-title":"Fish scale-based biochar with defined pore size and ultrahigh specific surface area for highly efficient adsorption of ciprofloxacin","volume":"287","author":"Dou","year":"2022","journal-title":"Chemosphere"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.indcrop.2018.05.034","article-title":"An efficient strategy for enhancing enzymatic saccharification with delignified fungus Myrothecium verrucaria and solid acid","volume":"121","author":"Su","year":"2018","journal-title":"Ind. Crop. Prod."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Chen, X., Yu, G., Chen, Y., Tang, S., and Su, Y. (2022). Cow dung-based biochar materials prepared via Mixed base and its application in the removal of organic pollutants. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms231710094"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Yang, X., Lotfy, V.F., Basta, A.H., Liu, H., and Fu, S. (2024). Carbon quantum dots derived from rice straw doped with N and S and its nanocomposites with hydroxypropyl cellulose nanocomposite. Int. J. Biol. Macromol., 278.","DOI":"10.1016\/j.ijbiomac.2024.134925"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"109956","DOI":"10.1016\/j.envres.2020.109956","article-title":"A facile synthesis of nitrogen-doped porous carbons from lignocellulose and protein wastes for VOCs sorption","volume":"189","author":"Shen","year":"2022","journal-title":"Environ. Res."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"123916","DOI":"10.1016\/j.fuel.2022.123916","article-title":"Investigation on a novel preparation process of B-COPNA resin from catalytic cracking diesel","volume":"320","author":"Fang","year":"2022","journal-title":"Fuel"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"110947","DOI":"10.1016\/j.jece.2023.110947","article-title":"Lignocellulosic magnetic biochar with multiple functionality; A green chelating system for water purification","volume":"11","author":"John","year":"2023","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"145872","DOI":"10.1016\/j.cej.2023.145872","article-title":"Effect of biochar-derived dissolved organic matter on tetracycline sorption by KMnO4-modified biochar","volume":"474","author":"Yin","year":"2023","journal-title":"Chem. Eng. J."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jes.2018.01.013","article-title":"Mechanistic insights into sequestration of U(VI) toward magnetic biochar: Batch, XPS and EXAFS techniques","volume":"70","author":"Hu","year":"2018","journal-title":"J. Environ. Sci."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Akkoz, Y., and Coskun, R. (2023). Cellulose-supported bioadsorbent from natural hemp fiber for removal of anionic dyes from aqueous solution. Int. J. Biol. Macromol., 252.","DOI":"10.1016\/j.ijbiomac.2023.126447"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1016\/j.electacta.2009.10.040","article-title":"Relationship between the isoelectric point (pHpzc) and the potential of zero charge (Epzc) for passive metals","volume":"55","author":"McCafferty","year":"2010","journal-title":"Electrochimica Acta"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"140341","DOI":"10.1016\/j.chemosphere.2023.140341","article-title":"Carbon-based materials as efficient adsorbents for the removal of antibiotics: The real contributions of carbon edge sites","volume":"344","author":"He","year":"2023","journal-title":"Chemosphere"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"111289","DOI":"10.1016\/j.inoche.2023.111289","article-title":"Adsorption of yttrium by the sodium-modified titanium dioxide: Kinetic, equilibrium studies and investigation of Na-TiO2 radiation resistance","volume":"156","author":"Mironyuk","year":"2023","journal-title":"Inorg. Chem. Commun."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"125210","DOI":"10.1016\/j.seppur.2023.125210","article-title":"Novel application of (NH4)2Mo3S13 for vanadium adsorption: Experiments, characterization, kinetic and equilibrium modeling","volume":"329","author":"Ali","year":"2024","journal-title":"Sep. Purif. Technol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"138165","DOI":"10.1016\/j.chemosphere.2023.138165","article-title":"Removal of pollutants from aqueous product of Co-hydrothermal liquefaction: Adsorption and isotherm studies","volume":"321","author":"Adedeji","year":"2023","journal-title":"Chemosphere"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"116360","DOI":"10.1016\/j.envres.2023.116360","article-title":"Adsorption of antibiotics on bio-adsorbents derived from the forestry and agro-food industries","volume":"233","author":"Barreiro","year":"2023","journal-title":"Environ. Res."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"109159","DOI":"10.1016\/j.dib.2023.109159","article-title":"Isotherm data for adsorption of amoxicillin, ampicillin, and doripenem onto bentonite","volume":"48","author":"Yeo","year":"2023","journal-title":"Data Brief"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"131749","DOI":"10.1016\/j.colsurfa.2023.131749","article-title":"Development of CO2 adsorption materials from recycling spent tire char via orthogonal design: Optimal solution and thermodynamic evaluation","volume":"673","author":"Guo","year":"2023","journal-title":"Colloid. Surface. A."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"134149","DOI":"10.1016\/j.jclepro.2022.134149","article-title":"Sewage sludge-coconut fiber co-pyrolysis biochar: Mechanisms underlying synergistic heavy metal stabilization and ciprofloxacin adsorption","volume":"375","author":"Yang","year":"2022","journal-title":"J. Clean. Prod."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"103179","DOI":"10.1016\/j.algal.2023.103179","article-title":"Thermodynamic and kinetic insights into the adsorption mechanism of Cd(II) using Chlorella vulgaris cells with coverage modified by culture media engineering","volume":"74","author":"Tavernini","year":"2023","journal-title":"Algal Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"110598","DOI":"10.1016\/j.jece.2023.110598","article-title":"Efficient Removal of Pb(II), Cr(VI), and Tetracycline Hydrochloride from Aqueous Solutions Using UiO-66-AMP@PAN: Thermodynamics, Kinetics, and Isothermal Adsorption","volume":"11","author":"Qu","year":"2023","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Nie, Y., Zhao, C., Zhou, Z., Kong, Y., and Ma, J. (2023). Hydrochloric acid-modified fungi-microalgae biochar for adsorption of tetracycline hydrochloride: Performance and mechanism. Bioresour. Technol., 383.","DOI":"10.1016\/j.biortech.2023.129224"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"127103","DOI":"10.1016\/j.jhazmat.2021.127103","article-title":"Facile fabrication of N-doped hierarchical porous carbons derived from soft-templated ZIF-8 for enhanced adsorptive removal of tetracycline hydrochloride from water","volume":"423","author":"Zhang","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"126609","DOI":"10.1016\/j.jhazmat.2021.126609","article-title":"Mussel-inspired triple bionic adsorbent: Facile preparation of layered double hydroxide@polydopamine@metal-polyphenol networks and their selective adsorption of dyes in single and binary systems","volume":"420","author":"Gao","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"128445","DOI":"10.1016\/j.jhazmat.2022.128445","article-title":"Adsorption of dyes methyl violet and malachite green from aqueous solution on multi-step modified rice husk powder in single and binary systems: Characterization, adsorption behavior and physical interpretations","volume":"430","author":"You","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"137909","DOI":"10.1016\/j.jclepro.2023.137909","article-title":"Comprehensive understanding of tetracycline hydrochloride adsorption mechanism onto biochar-based gel pellets based on the combination of characteriza-tion-based and approximate site energy distribution methods","volume":"416","author":"Zhou","year":"2023","journal-title":"J. Clean. Prod."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"133981","DOI":"10.1016\/j.chemosphere.2022.133981","article-title":"Improved adsorption properties of tetracycline on KOH\/KMnO4 modified biochar derived from wheat straw","volume":"296","author":"Xu","year":"2022","journal-title":"Chemosphere"},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Nguyen, T., Nguyen, T., Chen, W., Chen, C., Bui, X., Patel, A.K., and Dong, C. (2023). Hydrothermal and pyrolytic conversion of sun-flower seed husk into novel porous biochar for efficient adsorption of tetracycline. Bioresour. Technol., 373.","DOI":"10.1016\/j.biortech.2023.128711"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"122217","DOI":"10.1016\/j.seppur.2022.122217","article-title":"From biochar to functions: Lignin induced formation of Fe3C in carbon\/Fe composites for efficient adsorption of tetracycline from wastewater","volume":"304","author":"Liu","year":"2022","journal-title":"Sep. Purif. Technol."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Chen, Y., Liu, J., Zeng, Q., Liang, Z., Ye, X., Lv, Y., and Liu, M. (2021). Preparation of Eucommia ulmoides lignin-based high-performance biochar containing sulfonic group: Synergistic pyrolysis mechanism and tetracycline hydrochloride adsorption. Bioresour. Technol., 329.","DOI":"10.1016\/j.biortech.2021.124856"},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Kozyatnyk, I., Oesterle, P., Wurzer, C., Masek, O., and Jansson, S. (2021). Removal of contaminants of emerging concern from multi-component systems using carbon dioxide activated biochar from lignocellulosic feedstocks. Bioresour. Technol., 340.","DOI":"10.1016\/j.biortech.2021.125561"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"112412","DOI":"10.1016\/j.micromeso.2022.112412","article-title":"Methodological approach to the chloramphenicol adsorption by acid-leached halloysites: Preparation, characterization, performance and mechanism","volume":"348","author":"Khelifa","year":"2022","journal-title":"Microporous Mesoporous Mater."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.scitotenv.2017.07.239","article-title":"Chloramphenicol interaction with functionalized biochar in water: Sorptive mechanism, molecular imprinting effect and repeatable application","volume":"609","author":"Ahmed","year":"2017","journal-title":"Sci. Total Environ."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"121516","DOI":"10.1016\/j.jclepro.2020.121516","article-title":"High-yield and high-performance porous biochar produced from pyrolysis of peanut shell with low-dose ammonium polyphosphate for chloramphenicol adsorption","volume":"264","author":"Yang","year":"2020","journal-title":"J. Clean. Prod."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"121374","DOI":"10.1016\/j.seppur.2022.121374","article-title":"Structure-performance correlation of high surface area and hierarchical porous biochars as chloramphenicol adsorbents","volume":"296","author":"Wang","year":"2022","journal-title":"Sep. Purif. Technol."}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/25\/21\/11387\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:18:35Z","timestamp":1760113115000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/25\/21\/11387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,23]]},"references-count":54,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["ijms252111387"],"URL":"https:\/\/doi.org\/10.3390\/ijms252111387","relation":{},"ISSN":["1422-0067"],"issn-type":[{"type":"electronic","value":"1422-0067"}],"subject":[],"published":{"date-parts":[[2024,10,23]]}}}