{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:35:56Z","timestamp":1760146556875,"version":"build-2065373602"},"reference-count":42,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T00:00:00Z","timestamp":1731542400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018227","name":"National Research Foundation of Ukraine","doi-asserted-by":"publisher","award":["2022.01\/0004"],"award-info":[{"award-number":["2022.01\/0004"]}],"id":[{"id":"10.13039\/100018227","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Traumatic skeletal muscle injury is a complex pathology caused by high-energy trauma to muscle tissue. Previously, a positive effect was established when C60 fullerene was administered against the background of muscle ischemia, mechanical muscle injury, and other muscle dysfunctions, which probably protected the muscle tissue from damage caused by oxidative stress. Using tensiometry and biochemical analysis, the biomechanical parameters of skeletal muscle contraction and biochemical indices of the blood of rats 15 days after traumatic injury of the soleus muscle caused by myocyte destruction by compression were studied. The intraperitoneal administration of C60 fullerene aqueous solution (C60FAS) in a daily dose of 1 mg\/kg improved its contractile function by 28\u201340 \u00b1 2% and the values of the investigated biochemical indices of the animals\u2019 blood by 15\u201334 \u00b1 2% relative to the trauma group. The obtained results indicate the potential ability of C60 fullerenes, as powerful antioxidants, to reduce the development of post-traumatic dysfunction of the soleus muscle.<\/jats:p>","DOI":"10.3390\/ijms252212206","type":"journal-article","created":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T04:15:49Z","timestamp":1731557749000},"page":"12206","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["C60 Fullerene Reduces the Development of Post-Traumatic Dysfunction in Rat Soleus Muscle"],"prefix":"10.3390","volume":"25","author":[{"given":"Yuriy","family":"Prylutskyy","sequence":"first","affiliation":[{"name":"ESC \u201cInstitute of Biology and Medicine\u201d, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dmytro","family":"Nozdrenko","sequence":"additional","affiliation":[{"name":"ESC \u201cInstitute of Biology and Medicine\u201d, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olexandr","family":"Motuziuk","sequence":"additional","affiliation":[{"name":"ESC \u201cInstitute of Biology and Medicine\u201d, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine"},{"name":"Faculty of Biology and Forestry, Lesya Ukrainka Volyn National University, 43025 Lutsk, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svitlana","family":"Prylutska","sequence":"additional","affiliation":[{"name":"Faculty of Plant Protection, Biotechnology and Ecology, National University of Life and Environmental Science of Ukraine, 03041 Kyiv, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0202-8042","authenticated-orcid":false,"given":"Kateryna","family":"Bogutska","sequence":"additional","affiliation":[{"name":"ESC \u201cInstitute of Biology and Medicine\u201d, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Abramchuk","sequence":"additional","affiliation":[{"name":"Faculty of Biology and Forestry, Lesya Ukrainka Volyn National University, 43025 Lutsk, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alevtyna","family":"Morenko","sequence":"additional","affiliation":[{"name":"Faculty of Biology and Forestry, Lesya Ukrainka Volyn National University, 43025 Lutsk, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1719-0512","authenticated-orcid":false,"given":"Daria","family":"Franskevych","sequence":"additional","affiliation":[{"name":"ESC \u201cInstitute of Biology and Medicine\u201d, Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Scharff","sequence":"additional","affiliation":[{"name":"Institute of Chemistry and Biotechnology, Technical University of Ilmenau, 98693 Ilmenau, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9315-4863","authenticated-orcid":false,"given":"Uwe","family":"Ritter","sequence":"additional","affiliation":[{"name":"Institute of Chemistry and Biotechnology, Technical University of Ilmenau, 98693 Ilmenau, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.5435\/00124635-200600001-00004","article-title":"Combat orthopaedics: A view from the trenches","volume":"14","author":"Covey","year":"2006","journal-title":"J. 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