{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T11:15:34Z","timestamp":1787483734781,"version":"build-2736575974"},"reference-count":149,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T00:00:00Z","timestamp":1733184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Science Basic Research Plan in Shaanxi Province of China","award":["2023-JC-YB-746"],"award-info":[{"award-number":["2023-JC-YB-746"]}]},{"name":"Natural Science Basic Research Plan in Shaanxi Province of China","award":["32071517"],"award-info":[{"award-number":["32071517"]}]},{"name":"National Natural Science Foundation of China","award":["2023-JC-YB-746"],"award-info":[{"award-number":["2023-JC-YB-746"]}]},{"name":"National Natural Science Foundation of China","award":["32071517"],"award-info":[{"award-number":["32071517"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Psoriasis is a chronic inflammatory skin disease caused by abnormal activation and immune system disorder. Despite the availability of several treatments, they only provide temporary relief, and there is a critical need for more effective therapies to manage this condition. Electrostimulation has been widely used as a physical stimulus in treating various diseases, and recent studies have shown its potential in psoriasis treatment. In this review, we explore the direct and indirect effects of electrostimulation in treating psoriasis and their underlying mechanisms (the decreased secretion of inflammatory cytokines, the loss of cell-to-cell connections, and the cAMP signaling pathway). Our findings suggest that electrostimulation therapy may offer a promising approach to treating psoriasis and developing wearable devices for its management.<\/jats:p>","DOI":"10.3390\/ijms252313005","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T09:18:32Z","timestamp":1733217512000},"page":"13005","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Electrostimulation: A Promising New Treatment for Psoriasis"],"prefix":"10.3390","volume":"25","author":[{"given":"Zhuo","family":"Zuo","sequence":"first","affiliation":[{"name":"Key Laboratory for Space Biosciences & Biotechnology, School of Life Sciences, Institute of Special Environmental Biophysics, Research Center of Special Environmental Biomechanics and Medical Engineering, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment, Northwestern Polytechnical University, Xi\u2019an 710072, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaxing","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Space Biosciences & Biotechnology, School of Life Sciences, Institute of Special Environmental Biophysics, Research Center of Special Environmental Biomechanics and Medical Engineering, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment, Northwestern Polytechnical University, Xi\u2019an 710072, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanwei","family":"Fang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Space Biosciences & Biotechnology, School of Life Sciences, Institute of Special Environmental Biophysics, Research Center of Special Environmental Biomechanics and Medical Engineering, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment, Northwestern Polytechnical University, Xi\u2019an 710072, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Space Biosciences & Biotechnology, School of Life Sciences, Institute of Special Environmental Biophysics, Research Center of Special Environmental Biomechanics and Medical Engineering, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment, Northwestern Polytechnical University, Xi\u2019an 710072, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6960-0958","authenticated-orcid":false,"given":"Zhouqi","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Space Biosciences & Biotechnology, School of Life Sciences, Institute of Special Environmental Biophysics, Research Center of Special Environmental Biomechanics and Medical Engineering, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment, Northwestern Polytechnical University, Xi\u2019an 710072, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Jia","sequence":"additional","affiliation":[{"name":"Key Laboratory for Space Biosciences & Biotechnology, School of Life Sciences, Institute of Special Environmental Biophysics, Research Center of Special Environmental Biomechanics and Medical Engineering, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment, Northwestern Polytechnical University, Xi\u2019an 710072, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6811-5926","authenticated-orcid":false,"given":"Yulong","family":"Sun","sequence":"additional","affiliation":[{"name":"Key Laboratory for Space Biosciences & Biotechnology, School of Life Sciences, Institute of Special Environmental Biophysics, Research Center of Special Environmental Biomechanics and Medical Engineering, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment, Northwestern Polytechnical University, Xi\u2019an 710072, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Nguyen, A.V., and Soulika, A.M. 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