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Ophthalmol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.actbio.2021.09.054","article-title":"Mussel-Inspired Epoxy Bioadhesive with Enhanced Interfacial Interactions for Wound Repair","volume":"136","author":"Du","year":"2021","journal-title":"Acta Biomater."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"eadh4327","DOI":"10.1126\/sciadv.adh4327","article-title":"Injectable, Self-healing Hydrogel Adhesives with Firm Tissue Adhesion and On-demand Biodegradation for Sutureless Wound Closure","volume":"9","author":"Ren","year":"2023","journal-title":"Sci. Adv."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"tkac033","DOI":"10.1093\/burnst\/tkac033","article-title":"Bridging Wounds: Tissue Adhesives\u2019 Essential Mechanisms, Synthesis and Characterization, Bioinspired Adhesives and Future Perspectives","volume":"10","author":"Xu","year":"2022","journal-title":"Burn. Trauma"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"11441","DOI":"10.1007\/s10853-023-08730-x","article-title":"Injectable Carrier Hydrogel for Diabetic Foot Ulcer Wound Repair","volume":"58","author":"Wang","year":"2023","journal-title":"J. Mater. Sci."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Zhu, X., Yuan, W., Li, Z., Lin, Y., Li, W., Ji, L., Wang, D., Zhang, H., and Wang, Y. (2023). Progress of Research on Antioxidants and Carriers for Skin Wound Repair. Processes, 11.","DOI":"10.3390\/pr11072069"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Zou, M.L., Teng, Y.Y., Wu, J.J., Liu, S.Y., Tang, X.Y., Jia, Y., Chen, Z.H., Zhang, K.W., Sun, Z.L., and Li, X. (2021). Fibroblasts: Heterogeneous Cells with Potential in Regenerative Therapy for Scarless Wound Healing. Front. Cell Dev. Biol., 9.","DOI":"10.3389\/fcell.2021.713605"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Feng, P., Luo, Y., Ke, C., Qiu, H., Wang, W., Zhu, Y., Hou, R., Xu, L., and Wu, S. (2021). Chitosan-Based Functional Materials for Skin Wound Repair: Mechanisms and Applications. Front. Bioeng. Biotechnol., 9.","DOI":"10.3389\/fbioe.2021.650598"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"12252","DOI":"10.1073\/pnas.192252799","article-title":"Evidence for Van Der Waals Adhesion in Gecko Setae","volume":"99","author":"Autumn","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"eabd9410","DOI":"10.1126\/sciadv.abd9410","article-title":"Direct Evidence of Acid-Base Interactions in Gecko Adhesion","volume":"7","author":"Singla","year":"2021","journal-title":"Sci. Adv."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1242\/jeb.155.1.103","article-title":"Adhesion and Detachment of the Toe Pads of Tree Frogs","volume":"155","author":"Hanna","year":"1991","journal-title":"J. Exp. Biol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/adfm.201202024","article-title":"Insights into the Adhesive Mechanisms of Tree Frogs using Artificial Mimics","volume":"23","author":"Drotlef","year":"2013","journal-title":"Adv. Funct. Mater."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S1672-6529(11)60040-1","article-title":"Adhesive Contact in Animal: Morphology, Mechanism and Bio-inspired Application","volume":"8","author":"Ji","year":"2011","journal-title":"J. Bionic Eng."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/01932699208943328","article-title":"Surface Properties of Normal and Damaged Corneal Epithelia","volume":"13","author":"Ashutosh","year":"1992","journal-title":"J. Dispers. Sci. Technol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"5604","DOI":"10.1021\/acs.chemrev.1c00815","article-title":"Supramolecular Adhesive Hydrogels for Tissue Engineering Applications","volume":"122","author":"Zhao","year":"2022","journal-title":"Chem. Rev."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e202200081","DOI":"10.1002\/asia.202200081","article-title":"Supramolecular Hydrogels: Design Strategies and Contemporary Biomedical Applications","volume":"17","author":"Omar","year":"2022","journal-title":"Chem. Asian J."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Yu, H., Xiao, Q., Qi, G., Chen, F., Tu, B., Zhang, S., Li, Y., Chen, Y., Yu, H., and Duan, P. (2022). A Hydrogen Bonds-Crosslinked Hydrogels with Self-Healing and Adhesive Properties for Hemostatic. Front. Bioeng. Biotechnol., 10.","DOI":"10.3389\/fbioe.2022.855013"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"4852","DOI":"10.1021\/acsami.1c18983","article-title":"Electrostatic Interaction-Based High Tissue Adhesive, Stretchable Microelectrode Arrays for the Electrophysiological Interface","volume":"14","author":"Tian","year":"2022","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2201798","DOI":"10.1002\/adhm.202201798","article-title":"Instant and Tough Adhesives for Rapid Gastric Perforation and Traumatic Pneumothorax Sealing","volume":"11","author":"Liu","year":"2022","journal-title":"Adv. Healthc. Mater."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1800671","DOI":"10.1002\/adma.201800671","article-title":"Topological Adhesion of Wet Materials","volume":"30","author":"Yang","year":"2018","journal-title":"Adv. Mater."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1038\/nmat4037","article-title":"Surface-initiated Self-healing of Polymers in Aqueous Media","volume":"13","author":"Ahn","year":"2014","journal-title":"Nat. Mater."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrmicro2415","article-title":"The Biofilm Matrix","volume":"8","author":"Flemming","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"15497","DOI":"10.1073\/pnas.2006389117","article-title":"Instant Tough Bioadhesive with Triggerable Benign Detachment","volume":"117","author":"Chen","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2009334","DOI":"10.1002\/adfm.202009334","article-title":"Barnacle Cement Proteins-Inspired Tough Hydrogels with Robust, Long-Lasting, and Repeatable Underwater Adhesion","volume":"31","author":"Fan","year":"2021","journal-title":"Adv. Funct. Mater."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"46816","DOI":"10.1021\/acsami.0c14959","article-title":"Antibacterial Zwitterionic Polyelectrolyte Hydrogel Adhesives with Adhesion Strength Mediated by Electrostatic Mismatch","volume":"12","author":"Wang","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"7344","DOI":"10.1002\/adma.201504059","article-title":"Self-Adjustable Adhesion of Polyampholyte Hydrogels","volume":"27","author":"Roy","year":"2015","journal-title":"Adv. Mater."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"100803","DOI":"10.1016\/j.eml.2020.100803","article-title":"Topological Adhesion. I. Rapid and Strong Topohesives","volume":"39","author":"Steck","year":"2020","journal-title":"Extrem. Mech. Lett."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Bhatia, S.K. (2010). Biomaterials for Clinical Applications, Springer Science & Business Media.","DOI":"10.1007\/978-1-4419-6920-0"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Farrar, D. (2011). 11\u2014Adhesives and Interfacial Phenomena in Wound Healing. Advanced Wound Repair Therapies, Woodhead Publishing.","DOI":"10.1533\/9780857093301"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1002\/jbm.1053","article-title":"A Tissue Sealant Based on Reactive Multifunctional Polyethylene Glycol","volume":"58","author":"Wallace","year":"2001","journal-title":"J. Biomed. Mater. Res."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"14084","DOI":"10.1021\/acs.chemrev.3c00380","article-title":"Bioadhesive Technology Platforms","volume":"123","author":"Wu","year":"2023","journal-title":"Chem. Rev."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"4321","DOI":"10.1016\/j.cclet.2022.01.024","article-title":"A Novel Corneal Adhesive Based on Functionally Coupled PEG-lysozyme Hydrogel for Wound Closure After Surgical Eye Surgery","volume":"33","author":"Zhang","year":"2022","journal-title":"Chin. Chem. Lett."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Ge, L., and Chen, S. (2020). Recent Advances in Tissue Adhesives for Clinical Medicine. Polymers, 12.","DOI":"10.3390\/polym12040939"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ijbiomac.2022.06.087","article-title":"Photocross-linked Silk Fibroin\/Hyaluronic Acid Hydrogel Loaded with hDPSC for Pulp Regeneration","volume":"215","author":"Wang","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1807333","DOI":"10.1002\/adma.201807333","article-title":"Design and Applications of Photoresponsive Hydrogels","volume":"31","author":"Li","year":"2019","journal-title":"Adv. Mater."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2300996","DOI":"10.1002\/smtd.202300996","article-title":"Photocurable and Temperature-Sensitive Bioadhesive Hydrogels for Sutureless Sealing of Full-Thickness Corneal Wounds","volume":"8","author":"Wang","year":"2023","journal-title":"Small Methods"},{"key":"ref_39","first-page":"196","article-title":"Natural Polymer-derived Photocurable Bioadhesive Hydrogels for Sutureless Keratoplasty","volume":"8","author":"Zhao","year":"2021","journal-title":"Bioact. Mater."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"3385","DOI":"10.1021\/acsnano.7b08969","article-title":"Polyphenol-Binding Amyloid Fibrils Self-Assemble into Reversible Hydrogels with Antibacterial Activity","volume":"12","author":"Hu","year":"2018","journal-title":"ACS Nano"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"2003207","DOI":"10.1002\/adfm.202003207","article-title":"A Universal Strategy for Tough Adhesion of Wet Soft Material","volume":"30","author":"Gao","year":"2020","journal-title":"Adv. Funct. Mater."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"22015","DOI":"10.1021\/acsnano.3c08625","article-title":"Injectable Antiswelling and High-Strength Bioactive Hydrogels with a Wet Adhesion and Rapid Gelling Process to Promote Sutureless Wound Closure and Scar-free Repair of Infectious Wounds","volume":"17","author":"Zhao","year":"2023","journal-title":"ACS Nano"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"121231","DOI":"10.1016\/j.carbpol.2023.121231","article-title":"An Injectable, Self-healing, and Antioxidant Collagen- and Hyaluronic Acid-based Hydrogel Mediated with Gallic Acid and Dopamine for Wound Repair","volume":"320","author":"Yang","year":"2023","journal-title":"Carbohydr. Polym."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1167\/iovs.04-1192","article-title":"Modified Chondroitin Sulfate Aldehyde Adhesive for Sealing Corneal Incisions","volume":"46","author":"Reyes","year":"2005","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1904732","DOI":"10.1002\/adma.201904732","article-title":"Tough Bonding, On-Demand Debonding, and Facile Rebonding between Hydrogels and Diverse Metal Surfaces","volume":"31","author":"Li","year":"2019","journal-title":"Adv. Mater."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1907478","DOI":"10.1002\/adfm.201907478","article-title":"Reversible Bioadhesives Using Tannic Acid Primed Thermally-Responsive Polymers","volume":"30","author":"Li","year":"2020","journal-title":"Adv. Funct. Mater."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.actbio.2022.09.049","article-title":"Sutureless Transplantation Using a Semi-interpenetrating Polymer Network Bioadhesive for Ocular Surface Reconstruction","volume":"153","author":"Jia","year":"2022","journal-title":"Acta Biomater."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"104873","DOI":"10.1016\/j.mtcomm.2022.104873","article-title":"Chitosan\/dialdehyde Starch Hybrid In Situ Forming Hydrogel for Ocular Delivery of Betamethasone","volume":"33","author":"Aslzad","year":"2022","journal-title":"Mater. Today Commun."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"2201108","DOI":"10.1002\/adfm.202201108","article-title":"Bio-Inspired Self-Hydrophobized Sericin Adhesive with Tough Underwater Adhesion Enables Wound Healing and Fluid Leakage Sealing","volume":"32","author":"Liu","year":"2022","journal-title":"Adv. Funct. Mater."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1167\/tvst.11.6.26","article-title":"Development of an In Situ Printing System with Human Platelet Lysate-Based Bio-Adhesive to Treat Corneal Perforations","volume":"11","author":"You","year":"2022","journal-title":"Transl. Vis. Sci. Technol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1021\/bm200039s","article-title":"Synthesis and Characterization of Dendron Cross-Linked PEG Hydrogels as Corneal Adhesives","volume":"12","author":"Oelker","year":"2011","journal-title":"Biomacromolecules"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.biomaterials.2019.03.016","article-title":"A Highly Efficient, in situ Wet-Adhesive Dextran Derivative Sponge for Rapid Hemostasis","volume":"205","author":"Liu","year":"2019","journal-title":"Biomaterials"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.ijbiomac.2021.08.132","article-title":"A Mussel-inspired Flexible Chitosan-based Bio-hydrogel as a Tailored Medical Adhesive","volume":"189","author":"Fuyu","year":"2021","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"111281","DOI":"10.1016\/j.matdes.2022.111281","article-title":"Tetra-armed PEG-based Rapid High-adhesion, Antibacterial and Biodegradable Pre-clinical Bioadhesives for Preventing Pancreas Leakage","volume":"224","author":"Yang","year":"2022","journal-title":"Mater. Des."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1167\/tvst.12.5.20","article-title":"Biomechanics of a Plant-Derived Sealant for Corneal Injuries","volume":"12","author":"Liu","year":"2023","journal-title":"Transl. Vis. Sci. Technol."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Kabir, H., Mahdavi, S.S., Abdekhodaie, M.J., Rafii, A.B., and Merati, M. (2024). Development of an In-situ Forming Collagen-based Hydrogel as a Regenerative Bioadhesive for Corneal Perforations. Int. J. Biol. Macromol., 278.","DOI":"10.1016\/j.ijbiomac.2024.134761"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3390\/jfb6020277","article-title":"Nanomedicine Approaches for Corneal Diseases","volume":"6","author":"Chaurasia","year":"2015","journal-title":"J. Funct. Biomater."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/ICU.0000000000000431","article-title":"Wound Closure and Tissue Adhesives in Clear Corneal Incision Cataract Surgery","volume":"29","author":"Tong","year":"2018","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.biomaterials.2019.01.011","article-title":"Ocular adhesives: Design, chemistry, crosslinking mechanisms, and applications","volume":"197","author":"Sharifi","year":"2019","journal-title":"Biomaterials"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"4346","DOI":"10.1039\/D0BM00624F","article-title":"A Natural Polymer Based Bioadhesive with Self-healing Behavior and Improved Antibacterial Properties","volume":"8","author":"Ke","year":"2020","journal-title":"Biomater. Sci."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1039\/D2BM01981G","article-title":"Long-term Antibacterial, Antioxidative, and Bioadhesive Hydrogel Wound Dressing for Infected Wound Healing Applications","volume":"11","author":"Dong","year":"2023","journal-title":"Biomater. Sci."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0021-5155(98)00018-5","article-title":"The Management of Retinal Detachments Associated with Choroidal Colobomas by Vitrectomy with Cyanoacrylate Retinopexy","volume":"42","author":"Hotta","year":"1998","journal-title":"Jpn. J. Ophthalmol."},{"key":"ref_63","first-page":"643","article-title":"Scleral Reinforcement by a Teflon Graft and a Tissue Adhesive","volume":"66","author":"Stenkula","year":"2009","journal-title":"Acta Ophthalmol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0161-6420(93)31674-X","article-title":"Clinical Experience with N-butyl Cyanoacryiate (Nexacryl) Tissue Adhesive","volume":"100","author":"Leahey","year":"1993","journal-title":"Ophthalmology"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"58","DOI":"10.2174\/1574888X16666210715112738","article-title":"Photo Cross-linkable Biopolymers for Cornea Tissue Healing","volume":"17","author":"Nozari","year":"2022","journal-title":"Curr. Stem Cell Res. Ther."},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Barroso, I.A., Man, K., Robinson, T.E., Cox, S.C., and Ghag, A.K. (2022). Photocurable GelMA Adhesives for Corneal Perforations. Bioengineering, 9.","DOI":"10.3390\/bioengineering9020053"},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Tang, Q., Lu, B., He, J., Chen, X., Fu, Q., Han, H., Luo, C., Yin, H., Qin, Z., and Lyu, D. (2022). Exosomes-loaded Thermosensitive Hydrogels for Corneal Epithelium and Stroma Regeneration. Biomaterials, 280.","DOI":"10.1016\/j.biomaterials.2021.121320"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1177\/08839115231167587","article-title":"Fabrication of Poloxamer Based Besifloxacin Thermosensitive in situ Gelling Nanoemulsions for Ophthalmic Delivery","volume":"38","author":"Kassaee","year":"2023","journal-title":"J. Bioact. Compat. Polym."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"eaba2187","DOI":"10.1126\/sciadv.aba2187","article-title":"LiQD Cornea: Pro-regeneration Collagen Mimetics as Patches and Alternatives to Corneal Transplantation","volume":"6","author":"McTiernan","year":"2020","journal-title":"Sci. Adv."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"2300192","DOI":"10.1002\/adhm.202300192","article-title":"ECM-Like Adhesive Hydrogel for the Regeneration of Large Corneal Stromal Defects","volume":"12","author":"Wang","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"104250","DOI":"10.1016\/j.jddst.2023.104250","article-title":"Hydrogel-based Formulations for Drug Delivery to the Anterior Segment of the Eye","volume":"81","author":"Akbari","year":"2023","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1208\/s12249-023-02516-9","article-title":"Ocular Drug Delivery: A Comprehensive Review","volume":"24","author":"Ahmed","year":"2023","journal-title":"AAPS PharmSciTech"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"20210106","DOI":"10.1002\/EXP.20210106","article-title":"Recent Advances in Overcoming Barriers to Cell-based Delivery Systems for Cancer Immunotherapy","volume":"2","author":"Ding","year":"2022","journal-title":"Exploration"},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Naghib, S.M., Ahmadi, B., Kangarshahi, B.M., and Mozafari, M.R. (2024). Chitosan-based Smart Stimuli-responsive Nanoparticles for Gene Delivery and Gene Therapy: Recent Progresses on Cancer Therapy. Int. J. Biol. Macromol., 278.","DOI":"10.1016\/j.ijbiomac.2024.134542"},{"key":"ref_75","doi-asserted-by":"crossref","unstructured":"Tarsitano, M., Mancuso, A., Cristiano, M.C., Urbanek, K., Torella, D., Paolino, D., and Fresta, M. (2023). Perspective Use of Bio-adhesive Liquid Crystals as Ophthalmic Drug Delivery Systems. Sci. Rep., 13.","DOI":"10.1038\/s41598-023-42185-z"},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Koivusalo, L., Kauppila, M., Samanta, S., Parihar, V.S., Ilmarinen, T., Miettinen, S., Oommen, O.P., and Skottman, H. (2019). Tissue Adhesive Hyaluronic Acid Hydrogels for Sutureless Stem Cell Delivery and Regeneration of Corneal Epithelium and Stroma. Biomaterials, 225.","DOI":"10.1016\/j.biomaterials.2019.119516"},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Rakhmetova, A., Yi, Z., Sarmout, M., and Koole, L.H. (2023). Sustained Release of Voriconazole Using 3D-Crosslinked Hydrogel Rings and Rods for Use in Corneal Drug Delivery. Gels, 9.","DOI":"10.3390\/gels9120933"},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Zhao, Y., Guo, P., Li, D., Liu, M., Zhang, J., Yuan, K., Zheng, H., and Liu, L. (2023). Preparation and Evaluation of Oxidized-dextran Based on Antibacterial Hydrogel for Synergistic Photodynamic Therapy. Int. J. Biol. Macromol., 253.","DOI":"10.1016\/j.ijbiomac.2023.127648"},{"key":"ref_79","first-page":"3062","article-title":"Injectable Bio-responsive Hydrogel for Therapy of Inflammation Related Eyelid Diseases","volume":"6","author":"Chen","year":"2021","journal-title":"Bioact. Mater."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"3936","DOI":"10.1016\/j.cclet.2021.03.037","article-title":"Bioinspired Self-assembly Supramolecular Hydrogel for Ocular Drug Delivery","volume":"32","author":"Li","year":"2021","journal-title":"Chin. Chem. Lett."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jconrel.2012.10.010","article-title":"Glaucoma Therapy by Extended Release of Timolol from Nanoparticle Loaded Silicone-hydrogel Contact Lenses","volume":"165","author":"Jung","year":"2013","journal-title":"J. Control. Release"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jconrel.2012.06.017","article-title":"Extended Drug Delivery by Contact Lenses for Glaucoma Therapy","volume":"162","author":"Peng","year":"2012","journal-title":"J. Control. Release"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S1773-2247(14)50021-4","article-title":"Review of Ophthalmic Drug Delivery by Contact Lenses","volume":"24","author":"Hsu","year":"2014","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref_84","doi-asserted-by":"crossref","unstructured":"Mondal, H., Kim, H.-J., Mohanto, N., and Jee, J.-P. (2023). A Review on Dry Eye Disease Treatment: Recent Progress, Diagnostics, and Future Perspectives. Pharmaceutics, 15.","DOI":"10.3390\/pharmaceutics15030990"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1080\/14737159.2021.1957833","article-title":"Application of Selected Biosensor Techniques in Clinical Diagnostics","volume":"21","author":"Olejnik","year":"2021","journal-title":"Expert Rev. Mol. Diagn."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1002\/adhm.201400504","article-title":"Contact Lens Sensors in Ocular Diagnostics","volume":"4","author":"Farandos","year":"2014","journal-title":"Adv. Healthc. Mater."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/IAE.0000000000003263","article-title":"Using RETeval System Flicker Electroretinography for Evaluation of Dense Vitreous Hemorrhage","volume":"42","author":"Han","year":"2022","journal-title":"Retina"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/lsm.21076","article-title":"Sutureless Sealing of Penetrating Corneal Wounds Using a Laser-activated Thin Film Adhesive","volume":"43","author":"Shahbazi","year":"2011","journal-title":"Lasers Surg. Med."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"997","DOI":"10.3109\/02713683.2011.606590","article-title":"Sealing and Healing of Clear Corneal Incisions with an Improved Dextran Aldehyde-PEG Amine Tissue Adhesive","volume":"36","author":"Chenault","year":"2011","journal-title":"Curr. Eye Res."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1021\/acssensors.3c00542","article-title":"Contact Lens Sensor with Anti-jamming Capability and High Sensitivity for Intraocular Pressure Monitoring","volume":"8","author":"Ren","year":"2023","journal-title":"ACS Sens."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.1016\/j.bios.2010.12.042","article-title":"A Contact Lens with Embedded Sensor for Monitoring Tear Glucose Level","volume":"26","author":"Yao","year":"2011","journal-title":"Biosens. Bioelectron."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.clae.2017.09.005","article-title":"Estimating Basal Tear Osmolarity in Normal and Dry Eye Subjects","volume":"41","author":"Willshire","year":"2018","journal-title":"Contact Lens Anterior Eye"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s40005-022-00573-z","article-title":"Smart pH-responsive Nanomedicines for Disease Therapy","volume":"52","author":"Shinn","year":"2022","journal-title":"J. Pharm. Investig."},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Wang, X., Xiao, Y., Deng, F., Chen, Y., and Zhang, H. (2021). Eye-Movement-Controlled Wheelchair Based on Flexible Hydrogel Biosensor and WT-SVM. 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