{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:30:28Z","timestamp":1785162628832,"version":"3.55.0"},"reference-count":24,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T00:00:00Z","timestamp":1738022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research Funds of Joint Research Center for Food Nutrition and Health of IHM","award":["2024SJY02"],"award-info":[{"award-number":["2024SJY02"]}]},{"name":"Research Funds of Joint Research Center for Food Nutrition and Health of IHM","award":["rc352007"],"award-info":[{"award-number":["rc352007"]}]},{"name":"the Introduction and Stabilization of Talent Projects of Anhui Agricultural University","award":["2024SJY02"],"award-info":[{"award-number":["2024SJY02"]}]},{"name":"the Introduction and Stabilization of Talent Projects of Anhui Agricultural University","award":["rc352007"],"award-info":[{"award-number":["rc352007"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Two new triterpenoid saponins, namely camsinsaponins A and B (1, 2), along with two known congeners (3, 4) were isolated from Camellia sinensis flowers. Their structures were determined by extensive spectroscopic data. All compounds were assessed for antifungal bioactivity against Candida albicans, Candida glabrata, and Candida tropicalis. Compounds 1\u20134 showed excellent inhibitory effects. Notably, in regard to compounds 1 and 2, their MIC values against C. albicans were close to those of the positive control, fluconazole. Furthermore, the inhibitory elements of compounds 1\u20134 on C. glabrata were better than those of fluconazole. The aforementioned findings offer valuable insights for future development of novel therapeutic strategies against drug-resistant infections.<\/jats:p>","DOI":"10.3390\/ijms26031147","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T10:44:30Z","timestamp":1738061070000},"page":"1147","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Two New Triterpenoid Saponins with Antifungal Activity from Camellia sinensis Flowers"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3480-3720","authenticated-orcid":false,"given":"Jian-Fa","family":"Zong","sequence":"first","affiliation":[{"name":"National Key Laboratory for Tea Plant Germplasm Innovation and Resource Utilization, Anhui Provincial Key Laboratory of Food Safety Monitoring and Quality Control, Joint Research Center for Food Nutrition and Health of IHM, Anhui Agricultural University, Hefei 230036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Bo","family":"Hong","sequence":"additional","affiliation":[{"name":"National Key Laboratory for Tea Plant Germplasm Innovation and Resource Utilization, Anhui Provincial Key Laboratory of Food Safety Monitoring and Quality Control, Joint Research Center for Food Nutrition and Health of IHM, Anhui Agricultural University, Hefei 230036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Hui","family":"Hu","sequence":"additional","affiliation":[{"name":"National Key Laboratory for Tea Plant Germplasm Innovation and Resource Utilization, Anhui Provincial Key Laboratory of Food Safety Monitoring and Quality Control, Joint Research Center for Food Nutrition and Health of IHM, Anhui Agricultural University, Hefei 230036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4423-694X","authenticated-orcid":false,"given":"Ru-Yan","family":"Hou","sequence":"additional","affiliation":[{"name":"National Key Laboratory for Tea Plant Germplasm Innovation and Resource Utilization, Anhui Provincial Key Laboratory of Food Safety Monitoring and Quality Control, Joint Research Center for Food Nutrition and Health of IHM, Anhui Agricultural University, Hefei 230036, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jiac.2018.10.007","article-title":"Antifungal Susceptibility Trend and Analysis of Resistance Mechanism for Candida Species Isolated from Bloodstream at a Japanese University Hospital","volume":"25","author":"Sakagami","year":"2019","journal-title":"J. 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