{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T21:24:38Z","timestamp":1792877078762,"version":"4.5.0"},"reference-count":90,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T00:00:00Z","timestamp":1751587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fujian Provincial Public Research Institute of Fundamental Research","award":["2022R1026005"],"award-info":[{"award-number":["2022R1026005"]}]},{"name":"Fujian Provincial Public Research Institute of Fundamental Research","award":["KJZD2025002"],"award-info":[{"award-number":["KJZD2025002"]}]},{"name":"Fujian Provincial Public Research Institute of Fundamental Research","award":["YCZX202412"],"award-info":[{"award-number":["YCZX202412"]}]},{"name":"Key Program of Fujian Academy of Agricultural Sciences","award":["2022R1026005"],"award-info":[{"award-number":["2022R1026005"]}]},{"name":"Key Program of Fujian Academy of Agricultural Sciences","award":["KJZD2025002"],"award-info":[{"award-number":["KJZD2025002"]}]},{"name":"Key Program of Fujian Academy of Agricultural Sciences","award":["YCZX202412"],"award-info":[{"award-number":["YCZX202412"]}]},{"name":"Research and Technology Program of Fujian Academy of Agricultural Sciences","award":["2022R1026005"],"award-info":[{"award-number":["2022R1026005"]}]},{"name":"Research and Technology Program of Fujian Academy of Agricultural Sciences","award":["KJZD2025002"],"award-info":[{"award-number":["KJZD2025002"]}]},{"name":"Research and Technology Program of Fujian Academy of Agricultural Sciences","award":["YCZX202412"],"award-info":[{"award-number":["YCZX202412"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Over the past decade, diseases associated with fowl adenoviruses (FAdVs) have exhibited a new epidemic trend worldwide. The presence of numerous FAdVs serotypes, combined with the virus\u2019s broad host range, positions it as a significant pathogen in the poultry industry. In the current context of intensive poultry production and global trade, co-infections involving multiple FAdVs serotypes, as well as co-infections with FAdVs alongside infectious bursal disease or infectious anemia virus, may occur within the same region or even on the same farm. The frequency of these outbreaks complicates the prevention and control of FAdVs. Therefore, the development of effective, targeted vaccines is essential for providing technical support in the management of FAdVs epidemics. Ongoing vaccine research aims to improve vaccine efficacy and address the challenges posed by emerging FAdVs outbreaks. This review focuses on vaccines developed and studied worldwide for various serotypes of FAdVs in the past decade. It encompasses inactivated vaccines, live attenuated vaccines, e.g., host-adapted attenuated vaccines and gene deletion vaccines, viral vector vaccines, and subunit vaccines (including VLP proteins and chimeric proteins). The current limitations and future development directions of FAdVs vaccine development are also proposed to provide a reference for new-generation vaccines and innovative vaccination strategies against FAdVs, as well as for the rapid development of highly effective vaccines.<\/jats:p>","DOI":"10.3390\/ijms26136434","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T03:47:26Z","timestamp":1751600846000},"page":"6434","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Advances and Prospects of Fowl Adenoviruses Vaccine Technologies in the Past Decade"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7148-4311","authenticated-orcid":false,"given":"Chunhua","family":"Zhu","sequence":"first","affiliation":[{"name":"Fujian Provincial Key Laboratory for Avian Diseases Control and Prevention, Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Yang","sequence":"additional","affiliation":[{"name":"Fujian Provincial Key Laboratory for Avian Diseases Control and Prevention, Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Fujian Provincial Key Laboratory for Avian Diseases Control and Prevention, Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9802-4232","authenticated-orcid":false,"given":"Xiaodong","family":"Liu","sequence":"additional","affiliation":[{"name":"Biotechnology Institute, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Huang","sequence":"additional","affiliation":[{"name":"Fujian Provincial Key Laboratory for Avian Diseases Control and Prevention, Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2011-5609","authenticated-orcid":false,"given":"Chunhe","family":"Wan","sequence":"additional","affiliation":[{"name":"Fujian Provincial Key Laboratory for Avian Diseases Control and Prevention, Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"001721","DOI":"10.1099\/jgv.0.001721","article-title":"ICTV Virus Taxonomy Profile: Adenoviridae 2022","volume":"103","author":"Benko","year":"2022","journal-title":"J. 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