{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T18:29:01Z","timestamp":1788805741757,"version":"build-2803163510"},"reference-count":50,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2025,8,16]],"date-time":"2025-08-16T00:00:00Z","timestamp":1755302400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>The expanding literature on nutraceuticals for male androgenetic alopecia (AGA) has inadvertently created knowledge gaps on the relative efficacy of conventional and non-conventional over-the-counter (OTC) treatments. We conducted a Bayesian network meta-analysis (NMA); the outcome measure was the 24-week change in total hair density (INPLASY202570087). We determined the relative efficacy of nine active comparators\u2014including topical minoxidil 5% and 2%. Among the topical OTC agents used to manage male AGA, minoxidil 5% applied twice daily was the most effective.<\/jats:p>","DOI":"10.3390\/ijms26167920","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T16:22:33Z","timestamp":1755534153000},"page":"7920","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparative Effect of Conventional and Non-Conventional Over-the-Counter Treatments for Male Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8664-7723","authenticated-orcid":false,"given":"Aditya K.","family":"Gupta","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 3H2, Canada"},{"name":"Mediprobe Research Inc., London, ON N5X 2P1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mesbah","family":"Talukder","sequence":"additional","affiliation":[{"name":"Mediprobe Research Inc., London, ON N5X 2P1, Canada"},{"name":"School of Pharmacy, BRAC University, Dhaka 1212, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Keene","sequence":"additional","affiliation":[{"name":"Physician\u2019s Hair Institute, Tucson, AZ 85712, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Williams","sequence":"additional","affiliation":[{"name":"Farjo Hair Institute, London W1G 7LH, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary A.","family":"Bamimore","sequence":"additional","affiliation":[{"name":"Mediprobe Research Inc., London, ON N5X 2P1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1473-2165.2005.00158.x","article-title":"The natural history of androgenetic alopecia","volume":"4","author":"Tosti","year":"2005","journal-title":"J. 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