{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T11:54:56Z","timestamp":1784289296783,"version":"3.55.0"},"reference-count":39,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Deanship of Graduate Studies and Scientific Research, Jazan University, Saudi Arabia","award":["RG24-S054"],"award-info":[{"award-number":["RG24-S054"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Mosquitoes pose a significant problem worldwide because of the diseases they transmit. Due to its antimicrobial and disinfectant properties, Commiphora myrrha (C. myrrha) has long been a popular choice in traditional medicine. This study aimed to extract C. myrrha using three different solvents\u2014methanol, acetone, and chloroform\u2014to identify their biochemical components and assess their larvicidal activity. The extracts were analyzed using gas chromatography\u2013mass spectrometry, and their effects were evaluated against Aedes aegypti. We identified 29, 41, and 19 phytoconstituents in the acetone, methanol, and chloroform extracts, respectively, with most belonging to the sesquiterpene and phenol categories. Larval mortality rates were recorded as follows: chloroform (100%), methanol (90%), and acetone (95%) extracts of C. myrrha at a concentration of 1000 ppm, 24 h post-treatment. After 72 h, the C. myrrha extracts showed effectiveness with LC50 values of 118.33, 127.67, and 142.13 ppm for chloroform, acetone, and methanol, respectively. The chloroform extract was the most effective in reducing the average number of eggs laid per day (234 eggs) compared to the untreated control group (1513 eggs) at 1000 ppm. These findings provide scientific evidence of the larvicidal efficacy of C. myrrha extracts and serve as valuable resources for developing plant-based pharmaceuticals.<\/jats:p>","DOI":"10.3390\/ijms26168050","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T08:02:44Z","timestamp":1755763364000},"page":"8050","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Larvicidal Effects and Phytochemical Analysis of Myrrh, Commiphora myrrh Chloroform, Methanol, and Acetone Extracts Against Dengue Vector Aedes aegypti L. (Diptera: Culicidae)"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9735-3501","authenticated-orcid":false,"given":"Abadi M.","family":"Mashlawi","sequence":"first","affiliation":[{"name":"Department of Biology, College of Science, Jazan University, Jazan 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanan","family":"Bosly","sequence":"additional","affiliation":[{"name":"Department of Biology, College of Science, Jazan University, Jazan 45142, Saudi Arabia"},{"name":"Environment and Nature Research Center, Jazan University, Jazan 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal Naif","family":"Alshammari","sequence":"additional","affiliation":[{"name":"Biology Department, Darb University College, Jazan University, Jazan 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5025-3079","authenticated-orcid":false,"given":"Naimah Asid H.","family":"Alanazi","sequence":"additional","affiliation":[{"name":"Department of Biology, College of Sciences, University of Ha\u2019il, Ha\u2019il 53962, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2573-9309","authenticated-orcid":false,"given":"Mohammed A.","family":"Akeel","sequence":"additional","affiliation":[{"name":"Human Anatomy Department, Faculty of Medicine, Jazan University, Jazan 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amani","family":"Alhejely","sequence":"additional","affiliation":[{"name":"Biology Department, Darb University College, Jazan University, Jazan 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahdah Ayed","family":"Alshammari","sequence":"additional","affiliation":[{"name":"Department of Biology, College of Science, Northern Border University, Arar 73241, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5428-9167","authenticated-orcid":false,"given":"Mohammed Abdullah","family":"Jeraiby","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Science, College of Medicine, Jazan University, Jazan 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naser Ahmed","family":"Alkenani","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3755-1135","authenticated-orcid":false,"given":"Salama A.","family":"Salama","sequence":"additional","affiliation":[{"name":"Department of Biology, College of Science, Jazan University, Jazan 45142, Saudi Arabia"},{"name":"Zoology Department, Faculty of Science, Damanhur University, Damanhur 22511, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Wilson, A.L., Courtenay, O., Kelly-Hope, L.A., Scott, T.W., Takken, W., Torr, S.J., and Lindsay, S.W. 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