{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T16:05:53Z","timestamp":1782489953580,"version":"3.54.5"},"reference-count":45,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T00:00:00Z","timestamp":1762128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Silver nanoparticles (AgNPs) were synthesized using a modified literature method involving aqueous AgNO3 (3 mM) and plant extract (LCE) at a constant ratio, under alkaline conditions and controlled temperature. The nanoparticles were characterized by UV-Vis spectroscopy, dynamic light scattering (DLS), zeta potential analysis and scanning transmission electron microscopy (STEM). The UV-Vis spectra displayed a broad absorption band around 450 nm, indicative of polydispersity, while DLS revealed a hydrodynamic diameter of 90.3 nm with a polydispersity index of 0.3366. Zeta potential values suggested reduced electrostatic stability compared with previously reported plant-derived AgNPs, although STEM images confirmed predominantly spherical, well-dispersed nanoparticles with sizes between 15 and 20 nm. Functional assays in zebrafish demonstrated the biological relevance of AgNPs. In scopolamine-induced models of cognitive and behavioral deficits, AgNPs treatment significantly improved memory and locomotor activity, as assessed by the Y-Maze, Novel Tank Diving Test and Novel Object Recognition Test.<\/jats:p>","DOI":"10.3390\/ijms262110693","type":"journal-article","created":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:15:14Z","timestamp":1762175714000},"page":"10693","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Eco-Friendly Synthesis of Silver Nanoparticles Using Lespedeza capitata Extract: Antioxidant and Anti-Inflammatory Properties in Zebrafish (Danio rerio)"],"prefix":"10.3390","volume":"26","author":[{"given":"Roxana Delia","family":"Chitiala","sequence":"first","affiliation":[{"name":"Grigore T. 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