{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T10:45:50Z","timestamp":1764153950520,"version":"3.46.0"},"reference-count":97,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>During pregnancy, the fetus is entirely dependent on maternal sources of vitamin D, which also regulates placental function. Vitamin D deficiency during pregnancy has been associated with intrauterine growth restriction (IUGR). This study aims to provide a narrative review of the potential influence of vitamin D deficiency on the pathogenesis of IUGR, and the potential benefits of vitamin D supplementation during pregnancy on fetal anthropometry. This review highlights the high prevalence of vitamin D deficiency among pregnant women and newborns worldwide, even in sunny countries. Most studies support that fetal vitamin D levels are directly related to maternal vitamin D levels. There is extensive literature confirming the relation between maternal vitamin D status and fetal growth patterns throughout pregnancy (both early and late). However, there is currently insufficient evidence to establish recommendations on optimal prenatal vitamin D supplementation in women to reduce the risk of IUGR.<\/jats:p>","DOI":"10.3390\/ijms262311422","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T10:04:57Z","timestamp":1764151497000},"page":"11422","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vitamin D and Intrauterine Growth Restriction (IUGR)"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4628-2213","authenticated-orcid":false,"given":"Teodoro","family":"Dur\u00e1-Trav\u00e9","sequence":"first","affiliation":[{"name":"Department of Pediatrics, School of Medicine, University of Navarra, 31008 Pamplona, Spain"},{"name":"Navarrabiomed (Biomedical Research Center), 31008 Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fidel","family":"Gallinas-Victoriano","sequence":"additional","affiliation":[{"name":"Navarrabiomed (Biomedical Research Center), 31008 Pamplona, Spain"},{"name":"Department of Pediatrics, Navarra University Hospital, 31008 Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.4161\/derm.24494","article-title":"Sunlight and Vitamin D: A global perspective for health","volume":"5","author":"Wacker","year":"2013","journal-title":"Derm.-Endocrinol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.mayocp.2013.05.011","article-title":"Vitamin D for health: A global perspective","volume":"88","author":"Holick","year":"2013","journal-title":"Mayo Clin. 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