{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:16:28Z","timestamp":1787163388296,"version":"build-2736575974"},"reference-count":100,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Jiangxi University of Chinese Medicine School-level Science and Technology Innovation Team Development Program","award":["CXTD22005"],"award-info":[{"award-number":["CXTD22005"]}]},{"name":"Jiangxi Province Key Laboratory of Pharmacology of Traditional Chinese Medicine","award":["2024SSY07111"],"award-info":[{"award-number":["2024SSY07111"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["No. 82160761"],"award-info":[{"award-number":["No. 82160761"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFF0705300"],"award-info":[{"award-number":["2022YFF0705300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Sesbania cannabina (Retz.) Poir. (S. cannabina), as an important leguminous plant in the genus Sesbania, plays a crucial role in agricultural sustainability and ecological restoration. This review systematically summarizes its current research status and conducts a comprehensive analysis of germplasm resources, chemical composition, biological activity and multi-field applications. Regarding germplasm resources, this article reviews the germplasm resource characteristics of Sesbania, which is widely distributed and has strong stress resistance, as well as its huge application potential in agriculture, ecological restoration and other fields. At the chemical composition level, this study reviews the chemical composition of various parts of Sesbania, with a focus on analyzing the dynamic change patterns of its rich secondary metabolites, and summarizes the related extraction, separation, and analytical identification methods. Regarding medicinal value and bioactivity, this article reviews the traditional medicinal value of S. cannabina, with a focus on exploring the mechanism of action and safety of its modern pharmacological activities such as antioxidation, anti-inflammation, and immunomodulation. In conclusion, the comprehensive value of S. cannabina is remarkable. Future research should delve deeply into its resources, clarify the active mechanism and develop high-value applications to fully tap into its multi-functional potential.<\/jats:p>","DOI":"10.3390\/ijms262412129","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T10:41:23Z","timestamp":1765968083000},"page":"12129","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Panoramic Research on Sesbania cannabina: Germplasm Resources, Phytochemical Constituents, Biological Activities, and Applications"],"prefix":"10.3390","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5860-6492","authenticated-orcid":false,"given":"Ni","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China"},{"name":"The Jiangxi Province Key Laboratory for Diagnosis, Treatment, and Rehabilitation of Cancer in Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhua","family":"Meng","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuiping","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duanrui","family":"Cao","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keping","family":"Hu","sequence":"additional","affiliation":[{"name":"Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9871-0753","authenticated-orcid":false,"given":"Xiaofeng","family":"Cao","sequence":"additional","affiliation":[{"name":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0576-0415","authenticated-orcid":false,"given":"Huanwen","family":"Chen","sequence":"additional","affiliation":[{"name":"The Jiangxi Province Key Laboratory for Diagnosis, Treatment, and Rehabilitation of Cancer in Chinese Medicine, Jiangxi University of Chinese Medicine, Nanchang 330004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Xia, T., Wang, T., Sun, J., Shi, W., Liu, Y., Huang, F., Zhang, J., and Zhong, J. 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