{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T14:36:39Z","timestamp":1767191799390,"version":"3.48.0"},"reference-count":211,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:00:00Z","timestamp":1766620800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"state budget of the Zhirmunsky National Scientific Center of Marine Biology (NSCMB) FEB RAS","award":["121082600034-5"],"award-info":[{"award-number":["121082600034-5"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>This review summarizes a growing collection of data on adult neurogenesis in various vertebrate species, with a focus on teleost fish and mammals. Teleost fish serve as exceptional models for studying the dynamics of the cell cycle and the functions of adult neural stem progenitor cells (aNSPCs) throughout the central nervous system (CNS). New information about the characteristics of cells in various areas of the telencephalon of non-model objects\u2014juvenile masu salmon Oncorhynchus masou and chum salmon Oncorhynchus keta\u2014during postembryonic ontogenesis and after traumatic injury expands the current understanding of the issue. The expression of molecular markers of adult-type glial precursors in the model zebrafish and non-model objects, juveniles O. masou and O. keta, was presented. Immunohistochemical (IHC) verification of BrdU and PCNA made it possible to identify a population of rapidly and slowly proliferating cells in the pallium of intact O. masou and after traumatic brain injury (TBI). In salmonids, unlike in mammals, progenitor cells are able to differentiate into neurons after injury. The expression of vimentin and GFAP in the aNSCPs has functional specificity. A comparative analysis of the expression of Pax transcription factors in various vertebrates and juveniles O. masou is presented. Pax genes maintain cells in an undifferentiated state and ensure the spatiotemporal formation of mature cell types in changing developing neurogenic niches. The functions of glutamine synthetase (GS) and H2S in the brains of vertebrates and juvenile chum salmon under intact conditions and after TBI are characterized. In fish, unlike mammals, as a result of TBI, neuronal conduction is restored in the injury area, whereas in mammals the regenerative process is complicated by neuroinflammation and culminates in the formation of a glial scar.<\/jats:p>","DOI":"10.3390\/ijms27010247","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:50:21Z","timestamp":1766710221000},"page":"247","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Regeneration-Associated Factors in the Regulation of Adult and Post-Traumatic Neurogenesis in the Forebrain of Fish and Other Vertebrates"],"prefix":"10.3390","volume":"27","author":[{"given":"Evgeniya V.","family":"Pushchina","sequence":"first","affiliation":[{"name":"A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva I.","family":"Zharikova","sequence":"additional","affiliation":[{"name":"A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3288","DOI":"10.1016\/j.cub.2017.09.052","article-title":"Life-Long Neurogenic Activity of Individual Neural Stem Cells and Continuous Growth Establish an Outside-In Architecture in the Teleost Pallium","volume":"27","author":"Furlan","year":"2017","journal-title":"Curr. Biol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"101865","DOI":"10.1016\/j.pneurobio.2020.101865","article-title":"Variations of telencephalic development that paved the way for neocortical evolution","volume":"194","year":"2020","journal-title":"Prog. Neurobiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e2206704119","DOI":"10.1073\/pnas.2206704119","article-title":"Adult neurogenesis acts as a neural regularizer","volume":"119","author":"Tran","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_4","first-page":"45","article-title":"Zebrafish as a translational regeneration model to study the activation of neural stem cells and role of their environment","volume":"30","author":"Ceci","year":"2018","journal-title":"Prog. Neurobiol."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Olivera-Pasilio, V., Lasserre, M., and Castell\u00f3, M.E. (2017). Cell Proliferation, Migration, and Neurogenesis in the Adult Brain of the Pulse Type Weakly Electric Fish, Gymnotus omarorum. Front. Neurosci., 11.","DOI":"10.3389\/fnins.2017.00437"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.neuroscience.2025.03.027","article-title":"Adult neurogenesis in the Uruguayan teleost species Austrolebias charrua and Gymnotus omarorum","volume":"573","author":"Rosillo","year":"2025","journal-title":"Neuroscience"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/cne.20571","article-title":"Proliferation, migration, neuronal differentiation, and long-term survival of new cells in the adult zebrafish brain","volume":"488","author":"Zupanc","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.ydbio.2006.03.040","article-title":"Neural stem cells and neurogenesis in the adult zebrafish brain: Origin, proliferation dynamics, migration and cell fate","volume":"295","author":"Grandel","year":"2006","journal-title":"Dev. Biol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/82_2012_297","article-title":"Teleost fish as a model system to study successful regeneration of the central nervous system","volume":"Volume 367","author":"Zupanc","year":"2013","journal-title":"New Perspectives in Regeneration"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e31045","DOI":"10.7554\/eLife.31045","article-title":"Movement maintains forebrain neurogenesis via peripheral neural feedback in larval zebrafish","volume":"7","author":"Hall","year":"2018","journal-title":"Elife"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/procel\/pwad003","article-title":"Recent progress and challenges in the treatment of spinal cord injury","volume":"14","author":"Tian","year":"2023","journal-title":"Protein Cell"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e12474","DOI":"10.1111\/ede.12474","article-title":"Telencephalic eversion in embryos and early larvae of four teleost species","volume":"26","author":"Folgueira","year":"2024","journal-title":"Evol. Dev."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"bpae073","DOI":"10.1093\/biomethods\/bpae073","article-title":"A reproducible method to study traumatic injury-induced zebrafish brain regeneration","volume":"9","author":"Srivastava","year":"2024","journal-title":"Biol. Methods Protoc."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1134\/S1062360417050071","article-title":"GFAP and PCNA Marking in the cerebellum of masu salmon\u2019s (Oncorhynchus masou) juvenile after mechanical injury","volume":"48","author":"Stukaneva","year":"2017","journal-title":"Russ. J. Dev. Biol."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Pushchina, E.V., Zharikova, E.I., and Varaksin, A.A. (2021). Mechanical Brain Injury Increases Cells\u2019 Production of Cystathionine \u03b2-Synthase and Glutamine Synthetase, but Reduces Pax2 Expression in the Telencephalon of Juvenile Chum Salmon, Oncorhynchus keta. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22031279"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Pushchina, E.V., Zharikova, E.I., and Varaksin, A.A. (2022). Expression of Doublecortin, Glial Fibrillar Acidic Protein, and Vimentin in the Intact Subpallium and after Traumatic Injury to the Pallium in Juvenile Salmon, Oncorhynchus masou. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23031334"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"jeb226357","DOI":"10.1242\/jeb.226357","article-title":"Adult neurogenesis in the central nervous system of teleost fish: From stem cells to function and evolution","volume":"224","author":"Zupanc","year":"2021","journal-title":"J. Exp. Biol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Verdile, N., Camin, F., Pavlovic, R., Pasquariello, R., Stuknyt\u0117, M., De Noni, I., Brevini, T.A.L., and Gandolfi, F. (2023). Distinct Organotypic Platforms Modulate Rainbow Trout (Oncorhynchus mykiss) Intestinal Cell Differentiation In Vitro. Cells, 12.","DOI":"10.3390\/cells12141843"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Seki, T. (2020). Understanding the Real State of Human Adult Hippocampal Neurogenesis From Studies of Rodents and Non-human Primates. Front. Neurosci., 14.","DOI":"10.3389\/fnins.2020.00839"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1614329","DOI":"10.1155\/2016\/1614329","article-title":"The Role of Adult-Born Neurons in the Constantly Changing Olfactory Bulb Network","volume":"2016","author":"Malvaut","year":"2016","journal-title":"Neural Plast."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1007\/s00221-023-06621-w","article-title":"The ventricular-subventricular, subgranular and subcallosal zones: Three niches of neural stem cells in the postnatal brain","volume":"241","year":"2023","journal-title":"Exp. Brain Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/nature02211","article-title":"Expression and function of orphan nuclear receptor TLX in adult neural stem cells","volume":"427","author":"Shi","year":"2004","journal-title":"Nature"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1101\/gad.1299505","article-title":"Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways","volume":"19","author":"Molofsky","year":"2005","journal-title":"Genes. Dev."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"3805","DOI":"10.1242\/dev.01204","article-title":"Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain","volume":"131","author":"Ferri","year":"2004","journal-title":"Development"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.tins.2005.03.003","article-title":"SOX2 functions in adult neural stem cells","volume":"28","author":"Episkopou","year":"2005","journal-title":"Trends Neurosci."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0361-9230(01)00769-9","article-title":"The proliferative ventricular zone in adult vertebrates: A comparative study using reptiles, birds, and mammals","volume":"57","author":"Flames","year":"2002","journal-title":"Brain Res. Bull."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/(SICI)1097-4695(199808)36:2<267::AID-NEU12>3.0.CO;2-B","article-title":"Adult neurogenesis: Fromcanaries to the clinic","volume":"36","author":"Goldman","year":"1998","journal-title":"J. Neurobiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1159\/000057569","article-title":"Adult neurogenesis and neuronal regeneration in the central nervous system of teleost fish","volume":"58","author":"Zupanc","year":"2001","journal-title":"Brain Behav. Evol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1023\/A:1008998832552","article-title":"Transgenic zebrafish for studying nervous system development and regeneration","volume":"10","author":"Goldman","year":"2001","journal-title":"Transgenic Res."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Mazzitelli-Fuentes, L.S., Rom\u00e1n, F.R., El\u00edas, J.R.C., Deleglise, E.B., and Mongiat, L.A. (2022). Spatial Learning Promotes Adult Neurogenesis in Specific Regions of the Zebrafish Pallium. Front. Cell Dev. Biol., 10.","DOI":"10.3389\/fcell.2022.840964"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1002\/cne.23065","article-title":"The cellular composition of neurogenic periventricular zones in the adult zebrafish forebrain","volume":"520","author":"Lindsey","year":"2012","journal-title":"J. Comp. Neurol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00427-012-0425-5","article-title":"Comparative aspects of adult neural stem cell activity in vertebrates","volume":"223","author":"Grandel","year":"2013","journal-title":"Dev. Genes. Evol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/(SICI)1097-4695(19971105)33:5<585::AID-NEU7>3.0.CO;2-0","article-title":"Birth, migration, incorporation, and death of vocal control neurons in adult songbirds","volume":"33","author":"Kirn","year":"1997","journal-title":"J. Neurobiol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0166-4328(03)00006-8","article-title":"Effect of age and testosterone on autumnal neurogenesis in male European starlings (Sturnus vulgaris)","volume":"143","author":"Absil","year":"2003","journal-title":"Behav. Brain Res."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/BF00318622","article-title":"Ultrastructural radioautographic analysis of neurogenesis in the hypothalamus of the adult frog, Rana temporaria, with special reference to physiological regeneration of the preoptic nucleus. II. Types of neuronal cells produced","volume":"271","author":"Polenov","year":"1993","journal-title":"Cell Tissue Res."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/cne.1056","article-title":"Ventricular proliferation zones in the brain of an adult teleost fish and their relation to neuromeres and migration (secondary matrix) zones","volume":"436","author":"Ekstrom","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/cne.901940202","article-title":"Neuronal increase in various areas of the nervous system of the guppy, Lebistes","volume":"194","author":"Birse","year":"1980","journal-title":"J. Comp. Neurol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/(SICI)1520-6408(1997)20:3<208::AID-DVG4>3.0.CO;2-B","article-title":"A goldfish Notch-3 homologue is expressed in neurogenic regions of embryonic, adult, and regenerating brain and retina","volume":"20","author":"Sullivan","year":"1997","journal-title":"Dev. Genet."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.devbrainres.2005.08.009","article-title":"Cell proliferation in the developing and adult hindbrain and midbrain of trout and medaka (teleosts): A segmental approach","volume":"160","author":"Candal","year":"2005","journal-title":"Brain Res. Dev. Brain Res."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/cne.21222","article-title":"Identification of aromatase-positive radial glial cells as progenitor cells in the ventricular layer of the forebrain in zebrafish","volume":"501","author":"Pellegrini","year":"2007","journal-title":"J. Comp. Neurol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/3-540-31265-X_14","article-title":"Neural stem cells: On where they hide, in which disguise, and how we may lure them out","volume":"174","author":"Berninger","year":"2006","journal-title":"Handb. Exp. Pharmacol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.neuroscience.2015.09.005","article-title":"Synergistic effects of diet and exercise on hippocampal function in chronically stressed mice","volume":"308","author":"Hutton","year":"2015","journal-title":"Neuroscience"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1242\/dev.124.10.1929","article-title":"Identification of a lineage of multipotent hematopoietic progenitors","volume":"124","author":"Morrison","year":"1997","journal-title":"Development"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/cne.901160307","article-title":"Evidence for division and transformations of neuroglia cells in the mouse brain, as derived from autoradiography after injection of thymidineH3","volume":"116","author":"Smart","year":"1961","journal-title":"J. Comp. Neurol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/cne.901240303","article-title":"Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats","volume":"124","author":"Altman","year":"1965","journal-title":"J. Comp. Neurol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0092-8674(00)80956-3","article-title":"Identification of a neural stem cell in the adult mammalian central nervous system","volume":"96","author":"Johansson","year":"1999","journal-title":"Cell"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0092-8674(00)80783-7","article-title":"Subventricular zone astrocytes are neural stem cells in the adult mammalian brain","volume":"97","author":"Doetsch","year":"1999","journal-title":"Cell"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/cne.20288","article-title":"Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus","volume":"478","author":"Seri","year":"2004","journal-title":"J. Comp. Neurol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1101\/gad.1272305","article-title":"p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity","volume":"19","author":"Kippin","year":"2005","journal-title":"Genes Dev."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1134\/S106236041705006X","article-title":"Persistent and reparative neurogenesis in the juvenile masu salmon Oncorhynchus masou telencephalon after mechanical injury","volume":"48","author":"Pushchina","year":"2017","journal-title":"Russ. J. Dev. Biol."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Pushchina, E.V., Zharikova, E.I., Varaksin, A.A., Prudnikov, I.M., and Tsyvkin, V.N. (2020). Proliferation, Adult Neuronal Stem Cells and Cells Migration in Pallium during Constitutive Neurogenesis and after Traumatic Injury of Telencephalon of Juvenile Masu Salmon, Oncorhynchus masou. Brain Sci., 10.","DOI":"10.3390\/brainsci10040222"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/BF02389022","article-title":"Bromodeoxyuridine: Diagnostic toll in biology and medicine. Part I: Historical perspectives, histochemical methods and cell kinetics","volume":"27","author":"Dolbeare","year":"1995","journal-title":"Histochem. J."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1002\/dneu.22145","article-title":"Age-related changes in stem cell dynamics, neurogenesis, apoptosis, and gliosis in the adult brain: A novel teleost fish model of negligible senescence","volume":"74","author":"Traniello","year":"2014","journal-title":"Dev. Neurobiol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s004290050232","article-title":"Postembrionic neural proliferation in the zebrafish forebrain and its relationship to prosomeric domains","volume":"329","author":"Wullimann","year":"1999","journal-title":"Anat. Embryol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/326515a0","article-title":"Cyclin\/PCNA is the auxiliary protein of DNA polymerase-\u03b4","volume":"326","author":"Bravo","year":"1987","journal-title":"Nature"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"7153","DOI":"10.1523\/JNEUROSCI.21-18-07153.2001","article-title":"Astrocytes give rise to new neurons in the adult mammalian hippocampus","volume":"21","author":"Seri","year":"2001","journal-title":"J. Neurosci."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/cne.903590302","article-title":"Expression of glial fibrillary acidic protein and its relation to tract formation in embryonic zebrafish (Danio rerio)","volume":"359","author":"Marcus","year":"1995","journal-title":"J. Comp. Neurol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"5627","DOI":"10.1242\/dev.01455","article-title":"Conserved and acquired features of neurogenin1 regulation","volume":"131","author":"Blader","year":"2004","journal-title":"Development"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1126\/science.1553558","article-title":"Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system","volume":"255","author":"Reynolds","year":"1992","journal-title":"Science"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1523\/JNEUROSCI.22-05-01784.2002","article-title":"Adult rodent neurogenic regions: The ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors","volume":"22","author":"Seaberg","year":"2002","journal-title":"J. Neurosci."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1038\/nm0302-268","article-title":"Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations","volume":"8","author":"Morshead","year":"2002","journal-title":"Nat. Med."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"3206","DOI":"10.1523\/JNEUROSCI.18-09-03206.1998","article-title":"Experience-induced neurogenesis in the senescent dentate gyrus","volume":"18","author":"Kempermann","year":"1998","journal-title":"J. Neurosci."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1474-9726.2006.00197.x","article-title":"The aging neurogenic subventricular zone","volume":"5","author":"Luo","year":"2006","journal-title":"Aging Cell"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"7907","DOI":"10.1523\/JNEUROSCI.1299-06.2006","article-title":"Origin of oligodendrocytes in the subventricular zone of the adult brain","volume":"26","author":"Menn","year":"2006","journal-title":"J. Neurosci."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1242\/dev.125.12.2251","article-title":"In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain","volume":"125","author":"Morshead","year":"1998","journal-title":"Development"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"14835","DOI":"10.1073\/pnas.0404180101","article-title":"Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors","volume":"101","author":"Consiglio","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jneumeth.2006.05.020","article-title":"Isolation, cultivation, and differentiation of neural stem cells from adult fish brain","volume":"158","author":"Hinsch","year":"2006","journal-title":"J. Neurosci. Methods"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/cne.903530205","article-title":"Proliferation zones in the brain of adult gymnotiform fish: A quantitative mapping study","volume":"353","author":"Zupanc","year":"1995","journal-title":"J. Comp. Neurol."},{"key":"ref_69","unstructured":"Wullimann, M., Rupp, B., and Reichert, H. (1998). Neuroanatomy of the Zebrafish Brain: A Topological Atlas, Birkh\u00e4user."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/S0306-4522(01)00215-9","article-title":"Neurogenesis in the olfactory bulb of adult zebrafish","volume":"105","author":"Byrd","year":"2001","journal-title":"Neuroscience"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0361-9230(01)00666-9","article-title":"The teleostean forebrain: A comparative and developmental view based on early proliferation, Pax6 activity and catecholaminergic organization","volume":"57","author":"Wullimann","year":"2002","journal-title":"Brain Res. Bull."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/j.1749-6632.1998.tb10582.x","article-title":"Addition of new cells to the olfactory bulb of adult zebrafish","volume":"855","author":"Byrd","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.brainres.2004.05.039","article-title":"Morphofunctional characterization of neuronal cells at different stages of maturation in granule cell layer of adult rat dentate gyrus","volume":"1017","author":"Ambrogini","year":"2004","journal-title":"Brain Res."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0896-6273(03)00843-2","article-title":"Doublecortin microtubule affinity is regulated by a balance of kinase and phosphatase activity at the leading edge of migrating neurons","volume":"41","author":"Schaar","year":"2004","journal-title":"Neuron"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S1044-7431(03)00207-0","article-title":"Transient calretinin-expression defines early postmitotic step of neuronal differentiation in adult hippocampus neurogenesis of mice","volume":"24","author":"Brandt","year":"2003","journal-title":"Mol. Cell. Neurosci."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1474-9726.2011.00781.x","article-title":"Adult neurogenesis in the short-lived teleost Nothobranchius furzeri: Localization of neurogenic niches, molecular characterization and effects of aging","volume":"11","author":"Tozzini","year":"2012","journal-title":"Aging Cell"},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Ayanlaja, A.A., Xiong, Y., Gao, Y., Ji, G., Tang, C., Abdikani Abdullah, Z., and Gao, D. (2017). Distinct features of doublecortin as a marker of neuronal migration and its implications in cancer cell mobility. Front. Mol. Neurosci., 10.","DOI":"10.3389\/fnmol.2017.00199"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/cne.20497","article-title":"Expression and estrogen-dependent regulation of the zebrafish brain aromatase gene","volume":"485","author":"Menuet","year":"2005","journal-title":"J. Comp. Neurol."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"5046","DOI":"10.1523\/JNEUROSCI.17-13-05046.1997","article-title":"Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain","volume":"17","author":"Doetsch","year":"1997","journal-title":"J. Neurosci."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0361-9230(96)00116-5","article-title":"Glial tubes in the rostral migratory stream of the adult rat","volume":"42","author":"Peretto","year":"1997","journal-title":"Brain Res. Bull."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.neulet.2003.10.024","article-title":"Identification and functional evidence of GABAergic neurons in parts of the brain of adult zebrafish (Danio rerio)","volume":"355","author":"Kim","year":"2004","journal-title":"Neurosci. Lett."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/cne.10445","article-title":"Odor-stimulated glutamatergic neurotransmission in the zebrafish olfactory bulb","volume":"454","author":"Edwards","year":"2002","journal-title":"J. Comp. Neurol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1038\/nn1479","article-title":"Neuronal fate determinants of adult olfactory bulb neurogenesis","volume":"8","author":"Saghatelyan","year":"2005","journal-title":"Nat. Neurosci."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"6997","DOI":"10.1523\/JNEUROSCI.1435-05.2005","article-title":"Pax6 is required for making specific subpopulations of granule and periglomerular neurons in the olfactory bulb","volume":"25","author":"Kohwi","year":"2005","journal-title":"J. Neurosci."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"4519","DOI":"10.1093\/nar\/gkf567","article-title":"Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins","volume":"30","author":"Kasashima","year":"2002","journal-title":"Nucleic Acids Res."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.gde.2012.12.006","article-title":"Mechanisms coordinating ELAV\/Hu mRNA regulons","volume":"23","author":"Keene","year":"2013","journal-title":"Curr. Opin. Genet. Dev."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0925-4773(98)00156-7","article-title":"Zebrafish contains two Pax6 genes involved in eye development","volume":"77","author":"Nornes","year":"1998","journal-title":"Mech. Dev."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0361-9230(01)00777-8","article-title":"Radial glial cells as neuronal precursors: A new perspective on the correlation of morphology and lineage restriction in the developing cerebral cortex of mice","volume":"57","author":"Hartfuss","year":"2002","journal-title":"Brain Res. Bull."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.tins.2003.09.011","article-title":"Glia as neural progenitor cells","volume":"26","author":"Goldman","year":"2003","journal-title":"Trends Neurosci."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0896-6273(04)00140-0","article-title":"Radial glia serve as neuronal progenitors in all regions of the central nervous system","volume":"41","author":"Klein","year":"2004","journal-title":"Neuron"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1046\/j.1432-1033.2003.03432.x","article-title":"Structure, mRNA expression and linkage mapping of the brain-type fatty acid-binding protein gene (FABP7) from zebrafish (Danio rerio)","volume":"270","author":"Liu","year":"2003","journal-title":"Eur. J. Biochem."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neulet.2004.07.035","article-title":"Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain","volume":"369","author":"Komitova","year":"2004","journal-title":"Neurosci. Lett."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.conb.2005.01.016","article-title":"Sox genes and neural progenitor identity","volume":"15","author":"Pevny","year":"2005","journal-title":"Curr. Opin. Neurobiol."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0171-9335(98)80105-2","article-title":"Zebrafish vimentin: Molecular characterization, assembly properties and developmental expression","volume":"77","author":"Conrad","year":"1998","journal-title":"Eur. J. Cell Biol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/glia.20971","article-title":"Heterogeneity in Progenitor Cell Subtypes in the Ventricular Zone of the Zebrafish Adult Telencephalon","volume":"58","author":"Chapouton","year":"2010","journal-title":"Glia"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0304-3940(95)11988-9","article-title":"Differential expression of two zebrafish emx homeoprotein mRNAs in the developing brain","volume":"198","author":"Morita","year":"1995","journal-title":"Neurosci. Lett."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"3475","DOI":"10.1523\/JNEUROSCI.14-06-03475.1994","article-title":"Combinatorial expression of three zebrafish genes related to distal-less: Part of a homeobox gene code for the head","volume":"14","author":"Akimenko","year":"1994","journal-title":"J. Neurosci."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1006\/dbio.2002.0738","article-title":"olig2 is required for zebrafish primary motor neuron and oligodendrocyte development","volume":"248","author":"Park","year":"2002","journal-title":"Appel. Dev. Biol."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1242\/dev.109.4.797","article-title":"Spatially and temporally restricted expression of Pax2 during murine neurogenesis","volume":"109","author":"Nornes","year":"1990","journal-title":"Development"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1006\/dbio.1994.1334","article-title":"The expression pattern of two zebrafish achaete-scute homolog (ash) genes is altered in the embryonic brain of the cyclops mutant","volume":"166","author":"Allende","year":"1994","journal-title":"Dev. Biol."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"4557","DOI":"10.1242\/dev.124.22.4557","article-title":"The activity of neurogenin1 is controlled by local cues in the zebrafish embryo","volume":"124","author":"Blader","year":"1997","journal-title":"Development"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/cne.11021","article-title":"Development of vimentin and glial fibrillary acidic protein immunoreactivities in the brain of gray mullet (Chelon Labrosus), an advanced teleost","volume":"469","author":"Arochena","year":"2004","journal-title":"J. Comp. Neurol."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"4831","DOI":"10.1242\/dev.072587","article-title":"Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors","volume":"138","author":"Kroehne","year":"2011","journal-title":"Development"},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s12035-014-8692-y","article-title":"Radial glia, the keystone of the development of the hippocampal dentate gyrus","volume":"51","author":"Xu","year":"2015","journal-title":"Mol. Neurobiol."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1146\/annurev.neuro.051508.135600","article-title":"The glial nature of embryonic and adult neural stem cells","volume":"32","author":"Kriegstein","year":"2009","journal-title":"Ann. Rev. Neurosci."},{"key":"ref_106","unstructured":"Privat, A., Gimenez-Ribota, M., and Ridet, J.L. (1995). Morphology of Astrocytes, Oxford University Press."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1083\/jcb.23.2.277","article-title":"The fine structure of the rat cerebellum. II. The stellate neurons, granule cells and glia","volume":"23","author":"Hendon","year":"1964","journal-title":"J. Cell. Biol."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/cne.902390107","article-title":"Glial fibrillary acidic (GFA) protein in vertebrates: Immunofluorescence and immunoblotting study with monoclonal and polyclonal antibodies","volume":"239","author":"Dahl","year":"1985","journal-title":"J. Comp. Neurol."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0378-1119(03)00526-2","article-title":"Structural and functional characterization of the zebrafish gene for glial fibrillary acidic protein, GFAP","volume":"310","author":"Nielsen","year":"2003","journal-title":"Gene"},{"key":"ref_110","first-page":"191","article-title":"Vimentin, the 57,000 molecular weight protein of fibroblasts filaments, is the major cytoskeletal component in immature glia","volume":"24","author":"Dahl","year":"1981","journal-title":"Eur. J. Cell Biol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1002\/cne.901930316","article-title":"Immunoperoxidase localization of glial fibrillary acidic protein in radial glial cells and astrocytes of the developing rhesus monkey brain","volume":"193","author":"Levitt","year":"1980","journal-title":"J. Comp. Neurol."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"5253","DOI":"10.1242\/dev.127.24.5253","article-title":"Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage","volume":"127","author":"Malatesta","year":"2000","journal-title":"Development"},{"key":"ref_113","unstructured":"Lara, J.M., Velasco, A., Alonso, J.R., and Aijon, J. (1995). Neuroglia in the CNS of Teleosts. Neuron\u2013Glia Interrelations During Phylogeny: I. Phylogeny and Ontogeny of Glial Cells, Humana Press."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s004290050108","article-title":"Expression of a low-molecular-weight (10 kDa) calcium binding protein in glial cells of the brain of the trout (Teleostei)","volume":"196","author":"Manso","year":"1997","journal-title":"Anat. Embryol."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s004290050193","article-title":"Astroglial architecture of the carp (Cyprinus carpio) brain as revealed by immunohistochemical staining against glial fibrillary acidic protein (GFAP)","volume":"198","author":"Kalman","year":"1998","journal-title":"Anat. Embryol."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1523\/JNEUROSCI.10-05-01600.1990","article-title":"Reticular astrocytes in the fish optic nerve: Macroglia with epithelial characteristics form an axially repeated lacework pattern, to which nodes of Ranvier are apposed","volume":"10","author":"Maggs","year":"1990","journal-title":"J. Neurosci."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1007\/BF00334758","article-title":"Die Faserglia des Selachiergehirns","volume":"39","author":"Horstmann","year":"1954","journal-title":"Z. Zellforsch. Mikrosk. Anat."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/0040-8166(93)90048-P","article-title":"An immunocytochemical and ultrastructural study of a specialized glial region of the medulla oblongata in a teleost, Chelon Labrosus","volume":"25","author":"Anadon","year":"1993","journal-title":"Tissue Cell"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/glia.1126","article-title":"Three-dimensional distribution of astrocytes in zebrafish spinal cord","volume":"36","author":"Kawai","year":"2001","journal-title":"Glia"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/jez.10134","article-title":"Distribution of GFAP immunoreactive structures in the rhombencephalon of the sterlet (Acipenser ruthenus) and its evolutionary implication","volume":"293","author":"Kalman","year":"2002","journal-title":"J. Exp. Zool."},{"key":"ref_121","first-page":"737","article-title":"Expression of vimentin and GFAP and development of the retina in the trout","volume":"317","author":"Pairault","year":"1994","journal-title":"C. R. Acad. Sci."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/cne.903360107","article-title":"Tanycytes in the sunfish brain: NADPH-diaphorase histochemistry and regional distribution","volume":"336","author":"Ma","year":"1993","journal-title":"J. Comp. Neurol."},{"key":"ref_123","first-page":"62","article-title":"Pax7 is requisite for maintenance of a subpopulation of superior collicular neurons and shows a diverging expression pattern to Pax3 during superior collicular development","volume":"8","author":"Zembrzycki","year":"2008","journal-title":"Dev. Biol."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.molcel.2008.11.002","article-title":"Inhibition of PAX3 by TGF-beta modulates melano- cyte viability","volume":"32","author":"Yang","year":"2008","journal-title":"Mol. Cell"},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1002\/bies.10014","article-title":"Modularity in vertebrate brain development and evolution","volume":"23","author":"Redies","year":"2001","journal-title":"Bioessays"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ydbio.2007.12.040","article-title":"Regulation of the development of tectal neurons and their projections by transcription factors Brn3a and Pax7","volume":"316","author":"Fedtsova","year":"2008","journal-title":"Dev. Biol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s00429-006-0083-3","article-title":"Pax3 and Pax7 expression and regulation in the avian embryo","volume":"211","author":"Otto","year":"2006","journal-title":"Anat. Embryol."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1242\/dev.117.3.1001","article-title":"Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord","volume":"117","author":"Goulding","year":"1993","journal-title":"Development"},{"key":"ref_129","doi-asserted-by":"crossref","unstructured":"Ponti, G., Peretto, P., and Bonfanti, L. (2008). Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits. PLoS ONE, 3.","DOI":"10.1371\/journal.pone.0002366"},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1242\/dev.127.11.2357","article-title":"Pax6 defines the di-mesencephalic boundary by repressing En1 and Pax2","volume":"127","author":"Matsunaga","year":"2000","journal-title":"Development"},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"6439","DOI":"10.1523\/JNEUROSCI.0700-08.2008","article-title":"A dlx2- and Pax6-dependent transcriptional code for periglomerular neuron specification in the adult olfactory bulb","volume":"28","author":"Brill","year":"2008","journal-title":"J. Neurosci."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1242\/dev.00450","article-title":"Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6","volume":"130","author":"Baumer","year":"2003","journal-title":"Development"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"4535","DOI":"10.1242\/dev.129.19.4535","article-title":"Pax6 is required for establishing naso-temporal and dorsal characteristics of the optic vesicle","volume":"129","author":"Marquardt","year":"2002","journal-title":"Development"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1242\/dev.02717","article-title":"Lhx1 and Lhx5 maintain the inhibitory-neurotransmitter status of interneurons in the dorsal spinal cord","volume":"134","author":"Pillai","year":"2007","journal-title":"Development"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"8335","DOI":"10.1523\/JNEUROSCI.5669-08.2009","article-title":"Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice","volume":"29","author":"Tuoc","year":"2009","journal-title":"J. Neurosci."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.ydbio.2008.01.008","article-title":"Key basic helix\u2013loop\u2013helix transcription factor genes Hes1 and Ngn2 are regulated by Pax3 during mouse embryonic development","volume":"316","author":"Nakazaki","year":"2008","journal-title":"Dev. Biol."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0012-1606(02)00046-5","article-title":"Pax6 regulates regional development and neuronal migration in the cerebral cortex","volume":"255","author":"Talamillo","year":"2003","journal-title":"Dev. Biol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1046\/j.1460-9568.2003.02424.x","article-title":"Subpial neuronal migration in the medulla oblongata of Pax-6-deficient rats","volume":"17","author":"Horie","year":"2003","journal-title":"Eur. J. Neurosci."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1111\/j.1365-2443.2006.00992.x","article-title":"Abnormal migration and distribution of neural crest cells in Pax6 heterozygous mutant eye, a model for human eye diseases","volume":"11","author":"Kanakubo","year":"2006","journal-title":"Genes Cells"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1046\/j.1440-169X.1997.00007.x","article-title":"Cranial anomaly of homozygous rSey rat is associated with a defect in the migration pathway of midbrain crest cells","volume":"39","author":"Kuratani","year":"1997","journal-title":"Dev. Growth Differ."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1023\/A:1025751914372","article-title":"Further studies on cortical tangential migration in wild type and Pax-6 mutant mice","volume":"31","author":"Valverde","year":"2002","journal-title":"J. Neurocytol."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ydbio.2010.07.007","article-title":"Pax2 coordinates epithelial morphogenesis and cell fate in the inner ear","volume":"345","author":"Christophorou","year":"2010","journal-title":"Dev. Biol."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.ydbio.2006.11.006","article-title":"Pax6 controls the proliferation rate of neuroepithelial progenitors from the mouse optic vesicle","volume":"301","author":"Duparc","year":"2007","journal-title":"Dev. Biol."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1002\/jnr.20596","article-title":"Expression of the transcription factor Pax 6 in the adult rat dentate gyrus","volume":"81","author":"Nacher","year":"2005","journal-title":"J. Neurosci. Res."},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ydbio.2007.03.017","article-title":"Alterations of rx1 and Pax6 expression levels at neural plate stages differentially affect the production of retinal cell types and maintenance of retinal stem cell qualities","volume":"306","author":"Zaghloul","year":"2007","journal-title":"Dev. Biol."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.ydbio.2007.02.012","article-title":"The on\/off of Pax6 controls the tempo of neuronal differentiation in the developing spinal cord","volume":"305","author":"Medevielle","year":"2007","journal-title":"Dev. Biol."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1111\/j.1365-2443.2005.00893.x","article-title":"Pax6 is required for production and maintenance of progenitor cells in postnatal hippocampal neurogenesis","volume":"10","author":"Maekawa","year":"2005","journal-title":"Genes Cells"},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"156","DOI":"10.4103\/1673-5374.243721","article-title":"Neurolin expression in the optic nerve and immunoreactivity of Pax6-positive niches in the brain of rainbow trout (Oncorhynchus mykiss) after unilateral eye injury","volume":"14","author":"Pushchina","year":"2019","journal-title":"Neural Regen. Res."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1134\/S1062360412010055","article-title":"Neurochemical markers of cells of the periventricular brain area in the masu salmon Oncorhynchus masou (Salmonidae)","volume":"43","author":"Pushchina","year":"2012","journal-title":"Russ. J. Dev. Biol."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"13","DOI":"10.4103\/1673-5374.126963","article-title":"Features of adult neurogenesis and neurochemical signaling in the Cherry salmon Oncorhynchus masou brain","volume":"8","author":"Pushchina","year":"2013","journal-title":"Neural Regen. Res."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.pneurobio.2011.08.012","article-title":"Pax genes during neural development and their potential role in neuroregeneration","volume":"95","author":"Thompson","year":"2011","journal-title":"Prog. Neuro."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.ydbio.2006.11.016","article-title":"Pax2 regulates neuronal-glial cell fate choice in the embryonic optic nerve","volume":"303","author":"Soukkarieh","year":"2007","journal-title":"Dev. Biol."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"4395","DOI":"10.1002\/cne.22463","article-title":"Expression of Pax6 and sox2 in adult olfactory epithelium","volume":"518","author":"Guo","year":"2010","journal-title":"J. Comp. Neurol."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.expneurol.2005.11.022","article-title":"Differential neurogenic potential of progenitor cells in dentate gyrus and CA1 sector of the postischemic adult monkey hippocampus","volume":"198","author":"Tonchev","year":"2006","journal-title":"Exp. Neurol."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"9814","DOI":"10.1523\/JNEUROSCI.21-24-09814.2001","article-title":"Transcription factor expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord","volume":"21","author":"Yamamoto","year":"2001","journal-title":"J. Neurosci."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"19508","DOI":"10.1073\/pnas.0807453105","article-title":"Stimulation of neural regeneration in the mouse retina","volume":"105","author":"Karl","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1242\/jeb.003905","article-title":"Induction of four glutamine synthetase genes in brain of rainbow trout in response to elevated environmental ammonia","volume":"210","author":"Wright","year":"2007","journal-title":"J. Exp. Biol."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.1073\/pnas.90.7.3009","article-title":"Evolution of the glutamine synthetase gene, one of the oldest existing and functioning genes","volume":"90","author":"Kumada","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1242\/jeb.039156","article-title":"Inhibition of glutamine synthetase during ammonia exposure in rainbow trout indicates a high reserve capacity to prevent brain ammonia toxicity","volume":"213","author":"Sanderson","year":"2010","journal-title":"J Exp Biol."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00360-013-0781-0","article-title":"An in vitro analysis of intestinal ammonia handling in fasted and fed freshwater rainbow trout (Oncorhynchus mykiss)","volume":"184","author":"Rubino","year":"2014","journal-title":"J. Comp. Physiol. B"},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0166-445X(98)00094-0","article-title":"Response of carp central nervous system to hyperammonemic conditions: An immunocytochemical study of glutamine synthetase (GS), glial fibrillary acidic protein (GFAP) and 70 kDa heat-shock protein (HSP70)","volume":"45","author":"Bodega","year":"1999","journal-title":"Aquat. Toxicol."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.nurt.2010.05.015","article-title":"Astrocyte glutamine synthetase: Importance in hyperammonemic syndromes and potential target for therapy","volume":"7","author":"Brusilow","year":"2010","journal-title":"Neurotherapeutics"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/(SICI)1098-1136(199803)22:3<221::AID-GLIA2>3.0.CO;2-8","article-title":"Glutamine synthetase (GS) activity and spatial and temporal patterns of GS expression in the developing chick retina: Relationship with synaptogenesis in the outer plexiform layer","volume":"22","author":"Prada","year":"1998","journal-title":"Glia"},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0006-8993(92)91370-T","article-title":"Glutamine synthetase immunoreactivity in two types of mouse brain glial cells","volume":"586","author":"Miyake","year":"1992","journal-title":"Brain Res."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/BF00185897","article-title":"Astroglial pattern in the spinal cord of the adult barbel (Barbus comiza)","volume":"187","author":"Bodega","year":"1993","journal-title":"Anat. Embryol."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF02676355","article-title":"Effects of acute hyperammonemia in vivo and oxidative metabolism in nonsynaptic rat brain mitochondria","volume":"12","author":"Kosenko","year":"1997","journal-title":"Metab. Brain Dis."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0169-328X(89)90068-5","article-title":"The ontogeny and localization of glutamine synthetase gene expression in rat brain","volume":"6","author":"Mearow","year":"1989","journal-title":"Mol. Brain Res."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1159\/000111955","article-title":"Glutamine synthetase: A marker of an astroglial subpopulation in primary cultures of defined brain areas","volume":"10","author":"Fages","year":"1988","journal-title":"Dev. Neurosci."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1007\/BF01959739","article-title":"Glutamine synthetase during mouse brain development","volume":"38","author":"Caldani","year":"1982","journal-title":"Experientia"},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/978-3-319-08894-5_2","article-title":"Glutamate metabolism in the brain focusing on astrocytes","volume":"11","author":"Schousboe","year":"2014","journal-title":"Adv. Neurobiol."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/nrn1886","article-title":"Ageing and neuronal vulnerability","volume":"7","author":"Mattson","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/j.1471-4159.2006.03913.x","article-title":"The glutamate\/GABA-glutamine cycle: Aspects of transport, neurotransmitter homeostasis and ammonia transfer","volume":"98","author":"Bak","year":"2006","journal-title":"J. Neurochem."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/S0197-0186(99)00150-3","article-title":"Neuronal expression of glutamine synthetase in Alzheimer\u2019s disease indicates a profound impairment of metabolic interactions with astrocytes","volume":"36","author":"Robinson","year":"2000","journal-title":"Neurochem. Int."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"10540","DOI":"10.1073\/pnas.88.23.10540","article-title":"Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease","volume":"88","author":"Smith","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1042\/bj3150607","article-title":"Effect of glucose on rat glutamine synthetase in cultured astrocytes","volume":"315","author":"Rosier","year":"1996","journal-title":"Biochem. J."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0006-8993(92)90639-Q","article-title":"Brain glutamine synthetase increases following cerebral ischemia in the rat","volume":"569","author":"Petito","year":"1992","journal-title":"Brain Res."},{"key":"ref_177","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/S0047-6374(01)00249-4","article-title":"Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins Mech","volume":"122","author":"Butterfield","year":"2001","journal-title":"Ageing Dev."},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1046\/j.1471-4159.1997.68062451.x","article-title":"Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: Relevance to Alzheimer\u2019s disease","volume":"68","author":"Butterfield","year":"1997","journal-title":"J. Neurochem."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1093\/jnen\/63.10.1058","article-title":"Expression of excitatory amino acid transporter-1 (EAAT-1) in brain macrophages and microglia of patients with prion diseases","volume":"63","author":"Delisle","year":"2004","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1089\/ars.2016.6715","article-title":"Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells","volume":"26","author":"Palmieri","year":"2016","journal-title":"Antioxid. Redox Signal."},{"key":"ref_181","doi-asserted-by":"crossref","unstructured":"Pushchina, E.V., Stukaneva, M.E., and Varaksin, A.A. (2020). Hydrogen Sulfide Modulates Adult and Reparative Neurogenesis in the Cerebellum of Juvenile Masu Salmon, Oncorhynchus masou. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21249638"},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"7024","DOI":"10.1073\/pnas.94.13.7024","article-title":"Glutamine synthetase protects against neuronal degeneration in injured retinal tissue","volume":"94","author":"Gorovits","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996","article-title":"The possible role of hydrogen sulfide as an endogenous neuromodulator","volume":"16","author":"Abe","year":"1996","journal-title":"J. Neurosci."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1096\/fj.04-1815fje","article-title":"Hydrogen sulfide protects neurons from oxidative stress","volume":"18","author":"Kimura","year":"2004","journal-title":"FASEB J."},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.neuint.2013.11.002","article-title":"Role of hydrogen sulfide in secondary neuronal injury","volume":"64","author":"Wang","year":"2014","journal-title":"Neurochem. Int."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/978-981-16-4254-8_8","article-title":"Regulation of Ion Channel Function by Gas Molecules","volume":"Volume 1349","author":"Shah","year":"2021","journal-title":"Ion Channels in Biophysics and Physiology"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.neures.2005.07.002","article-title":"Modulating effect of hydrogen sulfide on gamma-aminobutyric acid B receptor in recurrent febrile seizures in rats","volume":"53","author":"Han","year":"2005","journal-title":"Neurosci. Res."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.neuroscience.2007.12.008","article-title":"Hydrogen sulphide in the hypothalamus causes an ATP-sensitive K+ channel-dependent decrease in blood pressure in freely moving rats","volume":"152","author":"Dawe","year":"2008","journal-title":"Neuroscience"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/jn\/134.3.489","article-title":"Glutathione metabolism and its implications for health","volume":"134","author":"Wu","year":"2004","journal-title":"J. Nutr."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1152\/japplphysiol.00938.2005","article-title":"Role of astrocytes in cerebrovascular regulation","volume":"100","author":"Koehler","year":"2006","journal-title":"J. Appl. Physiol."},{"key":"ref_191","doi-asserted-by":"crossref","unstructured":"Gamarra, M., de la Cruz, A., Blanco-Urrejola, M., and Baleriola, J. (2021). Local Translation in Nervous System Pathologies. Front. Integr. Neurosci., 15.","DOI":"10.3389\/fnint.2021.689208"},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s11062-011-9192-6","article-title":"Hydrogen Sulfide-, Parvalbumin-, and GABA-Producing Systems in the Masu Salmon Brain","volume":"43","author":"Puschina","year":"2011","journal-title":"Neurophysiology"},{"key":"ref_193","first-page":"85","article-title":"Gaseous intermediates in the brain of the salmon Oncorhynchus masou","volume":"48","author":"Pushchina","year":"2012","journal-title":"Zhurnal Evoliutsionnoi Biokhimii Fiziol."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/978-3-319-18144-8_3","article-title":"Physiological Roles of Hydrogen Sulfide and Polysulfides","volume":"Volume 230","author":"Kimura","year":"2015","journal-title":"Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide"},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.neuint.2019.01.027","article-title":"Signaling by hydrogen sulfide (H2S) and polysulfides (H2Sn) in the central nervous system","volume":"126","author":"Kimura","year":"2019","journal-title":"Neurochem. Int."},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s12987-022-00364-6","article-title":"Activation of NMDA receptors in brain endothelial cells increases transcellular permeability","volume":"19","author":"Kim","year":"2022","journal-title":"Fluids Barriers CNS"},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1134\/S1062360419020048","article-title":"Cystathionine-\u03b2-synthase in the brain of the trout Oncorhynchus mykiss after unilateral eye damage and in conditions of in vitro cultivation","volume":"50","author":"Pushchina","year":"2019","journal-title":"Russ. J. Dev. Biol."},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.brainresrev.2004.12.003","article-title":"Physiology of microglial cells","volume":"48","author":"Kettenmann","year":"2005","journal-title":"Brain Res."},{"key":"ref_199","first-page":"311","article-title":"Microglial cells in neurodegenerative disorders","volume":"43","author":"Wojtera","year":"2005","journal-title":"Folia Neuropathol."},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/emm.2006.40","article-title":"Microglia, major player in the brain inflammation: Their roles in the pathogenesis of Parkinson\u2019s disease","volume":"38","author":"Kim","year":"2006","journal-title":"Exp. Mol. Med."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/glia.20362","article-title":"Hydrogen sulphide regulates calcium homeostasis in microglial cells","volume":"54","author":"Lee","year":"2006","journal-title":"Glia"},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1134\/S1819712411010090","article-title":"Cystathionine \u03b2-synthase in the CNS of masu salmon Oncorhynchus masou (Salmonidae) and carp Cyprinus carpio (Cyprinidae)","volume":"5","author":"Pushchina","year":"2011","journal-title":"Neurochem. J."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.brainresrev.2010.02.004","article-title":"Neurotransmitter signaling in postnatal neurogenesis: The first leg","volume":"63","author":"Platel","year":"2010","journal-title":"Brain. Res. Rev."},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s11064-010-0127-1","article-title":"Developing brain as an endocrine organ: A paradoxical reality","volume":"35","author":"Ugrumov","year":"2010","journal-title":"Neurochem. Res."},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/bies.20221","article-title":"STOP and GO with NO: Nitric oxide as a regulator of cell motility in simple brains","volume":"27","author":"Bicker","year":"2005","journal-title":"BioEssays"},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jchemneu.2009.08.004","article-title":"Non-dopaminergic neurons partly expressing dopaminergic phenotype: Distribution in the brain, development and functional significance","volume":"38","author":"Ugrumov","year":"2009","journal-title":"J. Chem. Neuroanat."},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"8574","DOI":"10.1158\/0008-5472.CAN-06-0947","article-title":"Functional analysis of alternative isoforms of the transcription factor PAX3 in melanocytes in vitro","volume":"66","author":"Wang","year":"2006","journal-title":"Cancer Res."},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1038\/sj.bjp.0706277","article-title":"Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways","volume":"145","author":"Trevisani","year":"2005","journal-title":"Br. J. Pharmacol."},{"key":"ref_209","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1152\/ajplung.00053.2006","article-title":"Role of substance P in hydrogen sulfide-induced pulmonary inflammation in mice","volume":"291","author":"Bhatia","year":"2006","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"ref_210","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1080\/15216540500217875","article-title":"Hydrogen sulfide as a vasodilator","volume":"57","author":"Bhatia","year":"2005","journal-title":"IUBMB Life"},{"key":"ref_211","doi-asserted-by":"crossref","unstructured":"Pushchina, E.V., Pimenova, E.A., Kapustyanov, I.A., and Bykova, M.E. (2025). Ultrastructural Study and Immunohistochemical Characteristics of Mesencephalic Tegmentum in Juvenile Chum Salmon (Oncorhynchus keta) Brain After Acute Traumatic Injury. Int. J. Mol. Sci., 26.","DOI":"10.3390\/ijms26020644"}],"container-title":["International Journal of Molecular Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1422-0067\/27\/1\/247\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T14:34:11Z","timestamp":1767191651000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1422-0067\/27\/1\/247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,25]]},"references-count":211,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1]]}},"alternative-id":["ijms27010247"],"URL":"https:\/\/doi.org\/10.3390\/ijms27010247","relation":{},"ISSN":["1422-0067"],"issn-type":[{"type":"electronic","value":"1422-0067"}],"subject":[],"published":{"date-parts":[[2025,12,25]]}}}