{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:13:58Z","timestamp":1790424838297,"version":"4.1.0"},"reference-count":44,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the National Key Research and Development Program of China","award":["2022YFD1201600"],"award-info":[{"award-number":["2022YFD1201600"]}]},{"name":"Chongqing Special Program for Technological Innovation and Application Development","award":["CSTB2024TIAD-KPX0049"],"award-info":[{"award-number":["CSTB2024TIAD-KPX0049"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>The basic leucine zipper (bZIP) transcription factors play crucial roles in plant growth and stress adaptation. However, a comprehensive genome-wide analysis of this family has been lacking in the medicinal plant Coptis chinensis. In this study, we identified 55 bZIP genes (CcbZIPs) from the C. chinensis genome and systematically classified them into 12 subfamilies through phylogenetic analysis with Arabidopsis thaliana. Notably, subfamilies L and O were absent, while two orphan genes were discovered, indicating lineage-specific evolution. Expression profiling revealed that numerous CcbZIPs respond dynamically to temperature and light stresses in a tissue-specific manner. These findings provide a foundation for understanding the regulatory roles of CcbZIPs in environmental adaptation and secondary metabolism, offering potential genetic targets for future breeding aimed at improving stress tolerance and medicinal compound production in C. chinensis.<\/jats:p>","DOI":"10.3390\/ijms27010431","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T16:08:00Z","timestamp":1767197280000},"page":"431","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Genome-Wide Identification and Analysis of bZIP Transcription Factors in Coptis chinensis Reveals Their Regulatory Roles in Stress Responses"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4076-7900","authenticated-orcid":false,"given":"Wuke","family":"Wei","sequence":"first","affiliation":[{"name":"Chongqing Academy of Chinese Materia Medica, Chongqing 400065, China"},{"name":"Ministry of Education Key Laboratory of Chinese Medicinal Resource from Lingnan, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China"},{"name":"School of Life Sciences, Southwest University, Chongqing 400715, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7612-1658","authenticated-orcid":false,"given":"Zijian","family":"Le","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Southwest University, Chongqing 400715, China"},{"name":"School of Future Technology, University of Chinese Academy of Sciences, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianan","family":"Guo","sequence":"additional","affiliation":[{"name":"Chongqing Academy of Chinese Materia Medica, Chongqing 400065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rangyu","family":"Mo","sequence":"additional","affiliation":[{"name":"Chongqing Academy of Chinese Materia Medica, Chongqing 400065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Chongqing Academy of Chinese Materia Medica, Chongqing 400065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Pan","sequence":"additional","affiliation":[{"name":"Chongqing Academy of Chinese Materia Medica, Chongqing 400065, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.pbi.2018.05.001","article-title":"The Arabidopsis bZIP transcription factor family\u2014An update","volume":"45","author":"Snoek","year":"2018","journal-title":"Curr. 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