{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:20:27Z","timestamp":1787062827106,"version":"build-2736575974"},"reference-count":96,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012190","name":"Ministry of Science and Higher Education of the Russian Federation","doi-asserted-by":"crossref","award":["FSZE-2025-0003"],"award-info":[{"award-number":["FSZE-2025-0003"]}],"id":[{"id":"10.13039\/501100012190","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>Clathrate hydrates of carbon dioxide represent a subject of considerable interest in both fundamental science and the development of promising technologies. The phase behavior of CO2 hydrate in the presence of concentrated aqueous solutions remains poorly understood. In this study, we conducted a comprehensive investigation into the impact of magnesium chloride (0\u201324 mass%) and methanol (0\u201340 mass%) on the thermodynamic stability of CO2 hydrate. New experimental data on the three-phase gas\u2013aqueous solution\u2013gas hydrate equilibrium in the temperature range 243\u2013283 K and pressure range 1\u20134.5 MPa were obtained. A correlation is proposed for the precise representation of equilibrium pressure\u2013temperature lines. A comparison of the anti-hydrate effect, as indicated by the parameter \u2206Th, of these substances demonstrated that ionic MgCl2 exhibits a stronger thermodynamic inhibitory effect on CO2 hydrate formation than nonionic MeOH. The results of measuring the melting point of ice at 0.1 MPa for aqueous solutions of MgCl2 and MeOH confirmed the thermodynamic consistency of the hydrate equilibrium data. A detailed comparison of the anti-hydrate effect of MgCl2 and MeOH in a wide concentration range was performed on hydrates of different gases (CO2 and CH4). The phase composition of CO2 hydrate samples obtained from water and aqueous solutions of MgCl2 and MeOH was examined using powder X-ray diffraction (PXRD) at 133 K. The PXRD results indicate the formation of sI CO2 hydrate with a cell parameter of 11.86 \u00b1 0.04 \u00c5 in all cases.<\/jats:p>","DOI":"10.3390\/ijms27041792","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:09:19Z","timestamp":1770973759000},"page":"1792","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Thermodynamic Inhibition of Carbon Dioxide Hydrate with Magnesium Chloride and Methanol: Comparative Phase Equilibrium and PXRD Study"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0660-6233","authenticated-orcid":false,"given":"Anton","family":"Semenov","sequence":"first","affiliation":[{"name":"Department of Physical and Colloid Chemistry, Gubkin University, 65, Leninsky Prospekt, Building 1, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rais","family":"Mendgaziev","sequence":"additional","affiliation":[{"name":"Department of Physical and Colloid Chemistry, Gubkin University, 65, Leninsky Prospekt, Building 1, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2323-0151","authenticated-orcid":false,"given":"Andrey","family":"Stoporev","sequence":"additional","affiliation":[{"name":"Department of Physical and Colloid Chemistry, Gubkin University, 65, Leninsky Prospekt, Building 1, 119991 Moscow, Russia"},{"name":"Moscow Center for Advanced Studies, Kulakova Str. 20, 123592 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timur","family":"Tulegenov","sequence":"additional","affiliation":[{"name":"Department of Physical and Colloid Chemistry, Gubkin University, 65, Leninsky Prospekt, Building 1, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniil","family":"Lednev","sequence":"additional","affiliation":[{"name":"Department of Physical and Colloid Chemistry, Gubkin University, 65, Leninsky Prospekt, Building 1, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murtazali","family":"Yarakhmedov","sequence":"additional","affiliation":[{"name":"Department of Physical and Colloid Chemistry, Gubkin University, 65, Leninsky Prospekt, Building 1, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Istomin","sequence":"additional","affiliation":[{"name":"Department of Physical and Colloid Chemistry, Gubkin University, 65, Leninsky Prospekt, Building 1, 119991 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3723-9408","authenticated-orcid":false,"given":"Daria","family":"Sergeeva","sequence":"additional","affiliation":[{"name":"Department of Physical and Colloid Chemistry, Gubkin University, 65, Leninsky Prospekt, Building 1, 119991 Moscow, Russia"},{"name":"Center for Petroleum Science and Engineering, Skolkovo Institute of Science and Technology (Skoltech), Bolshoy Boulevard, 30, Building 1, 121205 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2015-7649","authenticated-orcid":false,"given":"Rawil","family":"Fakhrullin","sequence":"additional","affiliation":[{"name":"Institute of Fundamental Medicine and Biology, Kazan Federal University, Kreml uram\u0131 18, Kazan 420008, Republic of Tatarstan, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Sloan, E.D., and Koh, C.A. 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