{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:41:15Z","timestamp":1785415275857,"version":"3.56.0"},"reference-count":31,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Project Coordination, Implementation and Research Center, Yozgat Bozok University","award":["FED-2026-2190"],"award-info":[{"award-number":["FED-2026-2190"]}]},{"award":["FED-2026-2190"],"award-info":[{"award-number":["FED-2026-2190"]}],"id":[{"id":"https:\/\/ror.org\/04qvdf239","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>This study investigates the volatile composition of twelve medicinal plant species belonging to the Lamiaceae family, which are widely recognized for their diverse biological activities, including antioxidant, antibacterial, and antifungal properties. Despite extensive studies on essential oils, comparative analyses using solvent-free techniques under different microclimatic conditions remain limited. This study investigates the volatile compounds in twelve medicinal plants from the Lamiaceae family using headspace solid-phase microextraction coupled with gas chromatography\u2013mass spectrometry (HS-SPME\/GC-MS). Lamiaceae plants are recognized for their diverse medicinal properties, including antioxidative, antibacterial, and antifungal effects. A total of 74 volatile compounds were identified, encompassing terpenes, alcohols, esters, aldehydes, and ketones. Notably, Lavandula spica L. exhibited the highest number of unique volatiles (28), while Melissa officinalis L. had the fewest (16). Key compounds included Citral (65.48%) in Melissa officinalis L., Menthol (33.37%) and Menthyl acetate (30.53%) in Mentha piperita L., Carvone (45.86%) in Mentha spicata L., and Eucalyptol (54.71%) in Origanum syriacum L. Plants from Adana Botanic Park were rich in terpenes and ketones, whereas those from Osmaniye contained higher levels of alcohols, aldehydes, and esters. The findings emphasize the impact of geographic location on volatile profiles and suggest avenues for further research into medicinal efficacy and optimal dosage. This study supports the sustainable use of plant biodiversity (SDG 15) and highlights the importance of bioactive compounds for human health and well-being (SDG 3).<\/jats:p>","DOI":"10.3390\/ijms27104601","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:45:34Z","timestamp":1779291934000},"page":"4601","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of Volatile Compounds of Some Medicinal Plants from Lamiaceae Family by HS-SPME Method"],"prefix":"10.3390","volume":"27","author":[{"given":"Zeynep","family":"Ergun","sequence":"first","affiliation":[{"name":"Department of Biology, Faculty of Engineering and Natural Sciences, Osmaniye Korkut Ata University, Osmaniye 80000, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmira","family":"Ziya Motalebipour","sequence":"additional","affiliation":[{"name":"Department of Agronomy and Plant Breeding, Faculty of Agriculture, Water, Food and Nutraceuticals, Isf. C, Islamic Azad University, Isfahan 1477893780, Iran"},{"name":"Medicinal Plant Research Center, Isf. C., Islamic Azad University, Isfahan 1477893780, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nesibe Ebru","family":"Kafkas","sequence":"additional","affiliation":[{"name":"Department of Horticulture, Faculty of Agriculture, Cukurova University, Adana 01330, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5491-1430","authenticated-orcid":false,"given":"Mujgan","family":"Guney","sequence":"additional","affiliation":[{"name":"Department of Horticulture, Faculty of Agriculture, Yozgat Bozok University, Yozgat 66900, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.24263\/2304-974X-2019-8-2-3","article-title":"Characterization of aromatic compounds and antimicrobial properties of four spice essential oils from family Lamiaceae","volume":"8","author":"Fidan","year":"2019","journal-title":"Ukr. 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