{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:49:43Z","timestamp":1787028583915,"version":"build-2736575974"},"reference-count":65,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"National Science Centre","doi-asserted-by":"publisher","award":["2025\/09\/X\/ST4\/00422"],"award-info":[{"award-number":["2025\/09\/X\/ST4\/00422"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]},{"award":["2025\/09\/X\/ST4\/00422"],"award-info":[{"award-number":["2025\/09\/X\/ST4\/00422"]}],"id":[{"id":"https:\/\/ror.org\/03ha2q922","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJMS"],"abstract":"<jats:p>The integration of carbon nanomaterials with organic compounds offers a promising strategy for developing next-generation electrode materials with superior properties. A novel type of carbon paste electrode was fabricated by modifying a graphite matrix with functionalized multiwalled carbon nanotubes and juglone as a redox mediator, and then it was deposited by manual packing into a PEEK body (JUG-MWCNT\/CPE). The surface morphology and structural parameters of the composite materials were meticulously characterized using scanning electron microscopy (SEM), nitrogen adsorption\u2013desorption isotherms, and spectroscopic techniques, while their electrochemical properties were rigorously evaluated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). This study demonstrates that the synergistic interaction between the conductive nanotube network and the electroactive juglone significantly reduces the oxidation overpotential and enhances the peak current response of melatonin. Under optimized DPV parameters, the developed sensor presents outstanding analytical performance, featuring a wide linear response range from 0.002 to 0.16 mg L\u22121, a low detection limit of 0.49 \u00b5g L\u22121, excellent long-term signal stability for up to 30 days, and valid applicability for real-sample monitoring in commercial tablets and dietary supplements.<\/jats:p>","DOI":"10.3390\/ijms27146237","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T02:34:44Z","timestamp":1783996484000},"page":"6237","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Juglone\/MWCNT-Modified Electrode for High-Performance Melatonin Detection"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7732-0019","authenticated-orcid":false,"given":"Joanna","family":"Smajdor-Baran","sequence":"first","affiliation":[{"name":"Department of Analytical Chemistry and Biochemistry, Faculty of Materials Science and Ceramics, AGH University of Krakow, 30-059 Krakow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/j.1742-1241.2006.01191.x","article-title":"Melatonin: Therapeutic and Clinical Utilization","volume":"61","author":"Altun","year":"2007","journal-title":"Int. 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