{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:56:14Z","timestamp":1791374174633,"version":"4.3.1"},"reference-count":35,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. J. Mol. Sci.","IJMS"],"abstract":"<jats:p>Organ-specific allocation of phenolic metabolites may shape antioxidant responses in Crocus species. This study characterized stamen, pistil, tepal, perigon tube, and corm of Crocus cancellatus Herb. using ultrasound-assisted methanolic extraction, liquid chromatography\u2013tandem mass spectrometry with 30 authentic standards, six antioxidant assays, a relative antioxidant capacity index, Pearson correlation analysis, and principal component analysis. Twenty phenolic compounds were quantified. Hesperidin predominated in all organs and was highest in the tepal (17,660 \u00b1 60 \u03bcg\/g extract), approximately 43-fold above the corm. The pistil contained the highest 3-hydroxybenzoic acid (331 \u00b1 1 \u03bcg\/g extract) and 4-hydroxybenzoic acid (341 \u00b1 2 \u03bcg\/g extract), whereas the corm was enriched in pinoresinol (60.1 \u00b1 0.8 \u03bcg\/g extract) and uniquely contained vanillin (16.0 \u00b1 0.6 \u03bcg\/g extract). The tepal showed the highest total flavonoid content (81.50 \u00b1 0.40 mg RE\/g extract), while the stamen had the highest total phenolic content (12.63 \u00b1 0.05 mg GAE\/g extract). The corm showed the strongest DPPH radical scavenging (IC50 = 3.96 mg\/mL), whereas the pistil led in ABTS and FRAP responses. Principal component analysis explained 64.16% of total variance and separated the five organ profiles. These findings demonstrate organ-specific phenolic specialization and support targeted bioactivity studies.<\/jats:p>","DOI":"10.3390\/ijms27198904","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:34:31Z","timestamp":1791372871000},"page":"8904","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Organ-Specific Phenolic Specialization and Antioxidant Responses in Crocus cancellatus: LC\u2013MS\/MS and Multivariate Analysis"],"prefix":"10.3390","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5819-4894","authenticated-orcid":false,"given":"Bedrettin","family":"Selvi","sequence":"first","affiliation":[{"name":"Department of Biology, Faculty of Arts and Sciences, Tokat Gaziosmanpa\u015fa University, 60250 Tokat, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,10,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"113183","DOI":"10.1016\/j.jpba.2020.113183","article-title":"Comprehensive chemotaxonomic analysis of saffron crocus tepal and stamen samples, as raw materials with potential antidepressant activity","volume":"184","author":"Mottaghipisheh","year":"2020","journal-title":"J. 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