{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:50:21Z","timestamp":1760057421991,"version":"build-2065373602"},"reference-count":2,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T00:00:00Z","timestamp":1739059200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJNS"],"abstract":"<jats:p>The International Society for Neonatal Screening (ISNS) has supported the standardization of the measurement of key biochemical markers for the neonatal screening of diseases: thyroid-stimulating hormone (TSH) for congenital hypothyroidism, phenylalanine (PHE) for phenylketonuria, and 17\u03b1-hydroxyprogesterone (17OHP) for congenital adrenal hyperplasia. These diseases are commonly a part of neonatal screening panels worldwide. The ISNS provides a series of secondary reference materials to the manufacturers of neonatal screening reagents to assist in the production of calibration materials for kits. This technical note describes the manufacture of the seventh combined dried blood spot reference preparation for neonatal screening (RPNS) for these analytes.<\/jats:p>","DOI":"10.3390\/ijns11010013","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T03:39:47Z","timestamp":1739158787000},"page":"13","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seventh ISNS Reference Preparation for Neonatal Screening for Thyroid Stimulating Hormone, Phenylalanine, and 17\u03b1-Hydroxyprogesterone in Blood Spots"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5630-7322","authenticated-orcid":false,"given":"Peter C. J. I.","family":"Schielen","sequence":"first","affiliation":[{"name":"International Society for Neonatal Screening, Reigerskamp 273, 3607HP Maarssen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dianne","family":"Webster","sequence":"additional","affiliation":[{"name":"National Newborn Screening Laboratory, LabPlus, Health New Zealand Te Whatu Ora, Auckland 1023, New Zealand"},{"name":"Liggins Institute, University of Auckland, Auckland 1023, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Gerard","family":"Loeber","sequence":"additional","affiliation":[{"name":"International Society for Neonatal Screening, Reigerskamp 273, 3607HP Maarssen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9485-6754","authenticated-orcid":false,"given":"James R.","family":"Bonham","sequence":"additional","affiliation":[{"name":"Clinical Chemistry, Sheffield Children\u2019s NHSFT, Sheffield S10 2TH, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1007\/s10545-007-0622-y","article-title":"First ISNS Reference Preparation for Neonatal Screening for thyrotropin, phenylalanine and 17a-hydroxyprogesterone in blood spots","volume":"30","author":"Elvers","year":"2007","journal-title":"J. Inherit. Metab. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1053\/j.semperi.2009.12.003","article-title":"Improving and assuring newborn screening laboratory quality worldwide: 30-year experience at the Centers for Disease Control and Prevention","volume":"34","author":"Mei","year":"2010","journal-title":"Semin. Perinatol."}],"container-title":["International Journal of Neonatal Screening"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2409-515X\/11\/1\/13\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:29:50Z","timestamp":1760027390000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2409-515X\/11\/1\/13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,9]]},"references-count":2,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["ijns11010013"],"URL":"https:\/\/doi.org\/10.3390\/ijns11010013","relation":{},"ISSN":["2409-515X"],"issn-type":[{"type":"electronic","value":"2409-515X"}],"subject":[],"published":{"date-parts":[[2025,2,9]]}}}