{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:31:35Z","timestamp":1760059895704,"version":"build-2065373602"},"reference-count":13,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation Screening Improvement Program Award","doi-asserted-by":"publisher","award":["SHENOY23QI0","SESHAD23B0"],"award-info":[{"award-number":["SHENOY23QI0","SESHAD23B0"]}],"id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation Clinical Fellowship Award","doi-asserted-by":"publisher","award":["SHENOY23QI0","SESHAD23B0"],"award-info":[{"award-number":["SHENOY23QI0","SESHAD23B0"]}],"id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJNS"],"abstract":"<jats:p>An essential link in the cystic fibrosis (CF) newborn screening (NBS) process is communication of results. While this is described between NBS programs and primary care providers, data of this occurrence is limited with neonatologists. Neonatology providers represent a group caring for critically ill infants with conditions that can impact their ability to complete diagnostic testing after an abnormal NBS. Delays in testing can prolong time to diagnosis. We fielded a survey to assess neonatology provider knowledge and awareness of the Pennsylvania state CF NBS algorithm after an update occurred. Provider demographics, awareness of CF NBS update, and knowledge of the diagnostic testing process were measured. 86% of respondents were unaware of Pennsylvania CF NBS updates. Provider comfort with interpreting CF NBS results varied. 40% of providers identified the next diagnostic testing steps for a critically ill infant following an abnormal CF NBS. Our survey emphasizes the need for educating neonatology providers about CF NBS to improve knowledge and awareness of CF NBS algorithms to facilitate the early diagnosis of affected infants.<\/jats:p>","DOI":"10.3390\/ijns11030054","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T11:25:17Z","timestamp":1752751517000},"page":"54","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neonatology Providers Need Education About Cystic Fibrosis Newborn Screening Algorithms"],"prefix":"10.3390","volume":"11","author":[{"given":"Nilesh","family":"Seshadri","sequence":"first","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine, The Hub for Clinical Collaboration, Children\u2019s Hospital of Philadelphia, 3500 Civic Center Blvd., Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lori","family":"Christ","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Children\u2019s Hospital of Philadelphia, 3400 Civic Center Blvd., Philadelphia, PA 19104, USA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Munson","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Children\u2019s Hospital of Philadelphia, 3400 Civic Center Blvd., Philadelphia, PA 19104, USA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Borowiec","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine, The Hub for Clinical Collaboration, Children\u2019s Hospital of Philadelphia, 3500 Civic Center Blvd., Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4431-0644","authenticated-orcid":false,"given":"Clement L.","family":"Ren","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine, The Hub for Clinical Collaboration, Children\u2019s Hospital of Philadelphia, 3500 Civic Center Blvd., Philadelphia, PA 19104, USA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6942-9183","authenticated-orcid":false,"given":"Ambika","family":"Shenoy","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine, The Hub for Clinical Collaboration, Children\u2019s Hospital of Philadelphia, 3500 Civic Center Blvd., Philadelphia, PA 19104, USA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.jpeds.2016.09.065","article-title":"Diagnosis of Cystic Fibrosis in Screened Populations","volume":"181S","author":"Farrell","year":"2017","journal-title":"J. Pediatr."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"McGarry, M.E., Raraigh, K.S., Farrell, P., Shropshire, F., Padding, K., White, C., Dorley, M.C., Hicks, S., Ren, C.L., and Tullis, K. (2025). Cystic Fibrosis Newborn Screening: A Systematic Review-Driven Consensus Guideline from the United States Cystic Fibrosis Foundation. Int. J. Neonatal Screen., 11.","DOI":"10.3390\/ijns11020024"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1542\/peds.2006-1639","article-title":"Primary care physicians\u2019 attitudes regarding follow-up care for children with positive newborn screening results","volume":"118","author":"Kemper","year":"2006","journal-title":"Pediatrics"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"439","DOI":"10.46747\/cfp.6706439","article-title":"Primary care providers\u2019 role in newborn screening result notification for cystic fibrosis","volume":"67","author":"Hayeems","year":"2021","journal-title":"Can. Fam. Physician"},{"key":"ref_5","first-page":"57","article-title":"Newborn screening","volume":"31","author":"Pitt","year":"2010","journal-title":"Clin. Biochem. Rev."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1016\/j.jcf.2017.06.007","article-title":"Meconium ileus in Cystic Fibrosis","volume":"16","author":"Sathe","year":"2017","journal-title":"J. Cyst. Fibros."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jpeds.2007.03.002","article-title":"Diagnostic sweat testing: The Cystic Fibrosis Foundation guidelines","volume":"151","author":"LeGrys","year":"2007","journal-title":"J. Pediatr."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Iskrov, G., Angelova, V., Bochev, B., Valchinova, V., Gencheva, T., Dzhuleva, D., Dichev, J., Nedkova, T., Palkova, M., and Tyutyukova, A. (2023). Prospects for Expansion of Universal Newborn Screening in Bulgaria: A Survey among Medical Professionals. Int. J. Neonatal Screen., 9.","DOI":"10.3390\/ijns9040057"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1001\/jamapediatrics.2022.2674","article-title":"Real-world Associations of US Cystic Fibrosis Newborn Screening Programs With Nutritional and Pulmonary Outcomes","volume":"176","author":"Rosenfeld","year":"2022","journal-title":"JAMA Pediatr."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jcf.2016.04.001","article-title":"The benefits of newborn screening for cystic fibrosis: The Canadian experience","volume":"15","author":"Mak","year":"2016","journal-title":"J. Cyst. Fibros."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1001\/jamapediatrics.2017.0206","article-title":"Baby Observational and Nutrition Study (BONUS) Investigators of the Cystic Fibrosis Foundation Therapeutics Development Network. Effects of Diagnosis by Newborn Screening for Cystic Fibrosis on Weight and Length in the First Year of Life","volume":"171","author":"Leung","year":"2017","journal-title":"JAMA Pediatr."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/peds.107.1.1","article-title":"Early diagnosis of cystic fibrosis through neonatal screening prevents severe malnutrition and improves long-term growth. Wisconsin Cystic Fibrosis Neonatal Screening Study Group","volume":"107","author":"Farrell","year":"2001","journal-title":"Pediatrics"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.jcf.2024.09.011","article-title":"Cystic fibrosis foundation position paper: Redefining the cystic fibrosis care team","volume":"23","author":"Brown","year":"2024","journal-title":"J. Cyst. Fibros."}],"container-title":["International Journal of Neonatal Screening"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2409-515X\/11\/3\/54\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:11:14Z","timestamp":1760033474000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2409-515X\/11\/3\/54"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,17]]},"references-count":13,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,9]]}},"alternative-id":["ijns11030054"],"URL":"https:\/\/doi.org\/10.3390\/ijns11030054","relation":{},"ISSN":["2409-515X"],"issn-type":[{"type":"electronic","value":"2409-515X"}],"subject":[],"published":{"date-parts":[[2025,7,17]]}}}