{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:09:41Z","timestamp":1788260981462,"version":"build-2803163510"},"reference-count":23,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T00:00:00Z","timestamp":1680739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"US Department of Health and Human Services, Health Resources and Services Administration under Cooperative Agreement","award":["#U22MC24078"],"award-info":[{"award-number":["#U22MC24078"]}]},{"name":"US Department of Health and Human Services, Health Resources and Services Administration under Cooperative Agreement","award":["HHSH2502015000021\/HHSH25034005T"],"award-info":[{"award-number":["HHSH2502015000021\/HHSH25034005T"]}]},{"name":"Association of Public Health Laboratories and Contract","award":["#U22MC24078"],"award-info":[{"award-number":["#U22MC24078"]}]},{"name":"Association of Public Health Laboratories and Contract","award":["HHSH2502015000021\/HHSH25034005T"],"award-info":[{"award-number":["HHSH2502015000021\/HHSH25034005T"]}]},{"name":"Duke University","award":["#U22MC24078"],"award-info":[{"award-number":["#U22MC24078"]}]},{"name":"Duke University","award":["HHSH2502015000021\/HHSH25034005T"],"award-info":[{"award-number":["HHSH2502015000021\/HHSH25034005T"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJNS"],"abstract":"<jats:p>The Recommended Uniform Screening Panel (RUSP) is the list of conditions recommended by the US Secretary of Health and Human Services for inclusion in state newborn screening (NBS). During 2010\u20132022, seven conditions were added to the RUSP: severe combined immunodeficiency (SCID) (2010), critical congenital heart disease (CCHD) (2011), glycogen storage disease, type II (Pompe) (2015), mucopolysaccharidosis, type I (MPS I) (2016), X-linked adrenoleukodystrophy (X-ALD) (2016), spinal muscular atrophy (SMA) (2018), and mucopolysaccharidosis, type II (MPS II) (2022). The adoption of SCID and CCHD newborn screening by programs in all 50 states and three territories (Washington, D.C.; Guam; and Puerto Rico) took 8.6 and 6.8 years, respectively. As of December 2022, 37 programs screen for Pompe, 34 for MPS I, 32 for X-ALD, and 48 for SMA. The pace of implementation based on the average additional number of NBS programs per year was most rapid for SMA (11.3), followed by CCHD (7.8), SCID (6.2), MPS I (5.4), Pompe (4.9), and X-ALD (4.7).<\/jats:p>","DOI":"10.3390\/ijns9020020","type":"journal-article","created":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T02:29:58Z","timestamp":1680748198000},"page":"20","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Implementation of Newborn Screening for Conditions in the United States First Recommended during 2010\u20132018"],"prefix":"10.3390","volume":"9","author":[{"given":"Sikha","family":"Singh","sequence":"first","affiliation":[{"name":"Association of Public Health Laboratories, Silver Spring, MD 20910, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelili","family":"Ojodu","sequence":"additional","affiliation":[{"name":"Association of Public Health Laboratories, Silver Spring, MD 20910, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex R.","family":"Kemper","sequence":"additional","affiliation":[{"name":"Division of Primary Care Pediatrics, Nationwide Children\u2019s Hospital, Columbus, OH 43205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy K. K.","family":"Lam","sequence":"additional","affiliation":[{"name":"Clinical and Translational Science Institute, Duke University School of Medicine, Durham, NC 27710, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1078-6855","authenticated-orcid":false,"given":"Scott D.","family":"Grosse","sequence":"additional","affiliation":[{"name":"National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Watson, M.S., Lloyd-Puryear, M.A., and Howell, R.R. (2022). The progress and future of US newborn screening. Int. J. 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