{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:50:18Z","timestamp":1760237418184,"version":"build-2065373602"},"reference-count":28,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T00:00:00Z","timestamp":1589414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Grands-in-aid for Scientific Research","award":["No. 14256003, No. 19256002"],"award-info":[{"award-number":["No. 14256003, No. 19256002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Insects"],"abstract":"<jats:p>(1) Dengue is the most spread mosquito-borne viral disease in the world, and vector control is the only available means to suppress its prevalence, since no effective treatment or vaccine has been developed. A biological control program using copepods that feed on mosquito larvae has been practiced in Vietnam and some other countries, but the application of copepods was not always successful. (2) To understand why the utility of copepods varies, we evaluated the predation efficiency of a copepod species (Mesocyclops aspericornis) on a vector species (Aedes aegypti) by laboratory experiments under different temperatures, nutrition and prey-density conditions. (3) We found that copepod predation reduced intraspecific competition among Aedes larvae and then shortened the survivor\u2019s aquatic life and increased their pupal weight. In addition, the predatory efficiency of copepods was reduced at high temperatures. Furthermore, performance of copepod offspring fell when the density of mosquito larvae was high, probably because mosquito larvae had adverse effects on copepod growth through competition for food resources. (4) These results suggest that the increase in mosquitoes will not be suppressed solely by the application of copepods if the density of mosquito larvae is high or ambient temperature is high. We need to consider additional control methods in order to maintain the efficiency of copepods to suppress mosquito increase.<\/jats:p>","DOI":"10.3390\/insects11050307","type":"journal-article","created":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T10:27:19Z","timestamp":1589452039000},"page":"307","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Climate Change May Restrict the Predation Efficiency of Mesocyclops aspericornis (Copepoda: Cyclopidae) on Aedes aegypti (Diptera: Culicidae) Larvae"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4269-8753","authenticated-orcid":false,"given":"Nobuko","family":"Tuno","sequence":"first","affiliation":[{"name":"Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa 920-1192, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tran Vu","family":"Phong","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan"},{"name":"Department of Medical Entomology and Zoology, National Institute of Hygiene and Epidemiology, Hanoi 100000, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Takagi","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,5,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1365-2915.2008.00740.x","article-title":"Effect of dengue vector control interventions on entomological parameters in developing countries: A systematic review and meta-analysis","volume":"22","author":"Erlanger","year":"2008","journal-title":"Med. Veter-Entomol."},{"key":"ref_2","first-page":"613","article-title":"New strategy against Aedes aegypti in Vietnam","volume":"365","author":"Kay","year":"2005","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"822","DOI":"10.4269\/ajtmh.2010.09-0503","article-title":"Sustainability and Cost of a Community-Based Strategy Against Aedes aegypti in Northern and Central Vietnam","volume":"82","author":"Kay","year":"2010","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.4269\/ajtmh.2000.62.5","article-title":"National progress in dengue vector control in Vietnam: Survey for Mesocyclops (Copepoda), Micronecta (Corixidae), and fish as biological control agents","volume":"62","author":"Nam","year":"2000","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"850","DOI":"10.4269\/ajtmh.2012.11-0466","article-title":"Community-based control of Aedes aegypti by using Mesocyclops in southern Vietnam","volume":"86","author":"Nam","year":"2012","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_6","first-page":"689","article-title":"Elimination of Aedes albopictus from tire piles by introducing Macrocyclops albidus (Copepoda, Cyclopidae)","volume":"6","author":"Marten","year":"1990","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2987\/8756-971X(2007)23[65:CC]2.0.CO;2","article-title":"CYCLOPOID COPEPODS","volume":"23","author":"Marten","year":"2007","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/jvec.12355","article-title":"Predation on the invasive mosquito Aedes japonicus (Diptera: Culicidae) by native copepod species in Germany","volume":"44","author":"Kampen","year":"2019","journal-title":"J. Vector Ecol."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Udayanga, L., Ranathunge, T., Iqbal, M.C.M., Abeyewickreme, W., and Hapugoda, M. (2019). Predatory efficacy of five locally available copepods on Aedes larvae under laboratory settings: An approach towards bio-control of dengue in Sri Lanka. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0216140"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4269\/ajtmh.2005.72.67","article-title":"Elimination of dengue by community programs using Mesocyclops(Copepoda) against Aedes aegypti in central Vietnam","volume":"72","author":"Vu","year":"2005","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.actatropica.2014.10.006","article-title":"Social sustainability of Mesocyclops biological control for dengue in South Vietnam","volume":"141","author":"Tran","year":"2015","journal-title":"Acta Trop."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/tmi.12485","article-title":"Community effectiveness of copepods for dengue vector control: Systematic review","volume":"20","author":"Lazaro","year":"2015","journal-title":"Trop. Med. Int. Heal."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"02855","DOI":"10.1002\/ecs2.2855","article-title":"Finding the sweet spot: What levels of larval mortality lead to compensation or overcompensation in adult production?","volume":"10","author":"Neale","year":"2019","journal-title":"Ecosphere"},{"key":"ref_14","first-page":"305","article-title":"Prey and size preference of Mesocyclops longisetus (Copepoda) for Aedes albopictus and Culex quinquefasciatus larvae","volume":"20","author":"Soumare","year":"2004","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_15","first-page":"67","article-title":"Life history effects of prey choice by copepods: Implications for biocontrol of vector mosquitoes","volume":"19","author":"Dieng","year":"2003","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_16","first-page":"409","article-title":"A simple method for cultivating freshwater copepods used in biological control of Aedes aegypti","volume":"8","author":"Suarez","year":"1992","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_17","unstructured":"Dussart, B.H., and Defaye, D. (1995). Introduction to the Copepoda, SPD Academic."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/jmedent\/43.3.484","article-title":"Ecological factors influencing Aedes aegypti (Diptera: Culicidae) productivity in artificial containers in Salinas, Puerto Rico","volume":"43","author":"Barrera","year":"2006","journal-title":"J. Med Entomol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1590\/S0037-86822005000100014","article-title":"[Effect of larvae density on adult size of Aedes aegypti reared under laboratory condictions]","volume":"38","author":"Gama","year":"2005","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1046\/j.1365-2427.1997.00214.x","article-title":"Reproduction and adult longevity of five species of planktonic cyclopoid copepods reared on different diets: A comparative study","volume":"38","author":"Hopp","year":"1997","journal-title":"Freshw. Boil."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"20140135","DOI":"10.1098\/rstb.2014.0135","article-title":"Climate change influences on global distributions of dengue and chikungunya virus vectors","volume":"370","author":"Campbell","year":"2015","journal-title":"Philos. Trans. R. Soc. B"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/j.1365-2915.2011.00971.x","article-title":"Effects of temperature and diet on development and interspecies competition in Aedes aegypti and Aedes albopictus","volume":"26","author":"Farjana","year":"2011","journal-title":"Med Veter-Entomol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1603\/0022-2585-39.4.699","article-title":"Pupal mass and wing length as indicators of fecundity in Aedes albopictus and Aedes geniculatus (Diptera: Culicidae)","volume":"39","author":"Armbruster","year":"2002","journal-title":"J. Med. Entomol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/BF02374717","article-title":"La pr\u00e8dation du cope\u2019pode Mesocyclops leuckarti pilosa (Crustacea) sur les larves de Aedes (Stegomyia) aegypti et Ae. (St.) polynesiensis (Dip.: Culicidae): Essais pr\u00e8liminaires d\u2019utilisation comme agent de lutte biologique","volume":"26","author":"Thirel","year":"1981","journal-title":"Entomophaga"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"324","DOI":"10.4269\/ajtmh.1995.53.324","article-title":"Aedes aegypti control in the Lao People\u2019s Democratic Republic, with reference to copepods","volume":"53","author":"Jennings","year":"1995","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"483","DOI":"10.2987\/8756-971X(2006)21[483:SOTLCS]2.0.CO;2","article-title":"Sensitivity of the larvivorous copepod species, Mesocyclops pehpeiensis and Megacyclops viridis, to the insect growth regulator, pyriproxyfen","volume":"21","author":"Wang","year":"2005","journal-title":"J. Am. Mosq. Control. Assoc."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.exppara.2015.03.017","article-title":"Cymbopogon citratus-synthesized gold nanoparticles boost the predation efficiency of copepod Mesocyclops aspericornis against malaria and dengue mosquitoes","volume":"153","author":"Murugan","year":"2015","journal-title":"Exp. Parasitol."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Yakob, L., Funk, S., Camacho, A., Brady, O., and Edmunds, W.J. (2017). Aedes aegypti Control Through Modernized, Integrated Vector Management. PLoS Curr., 9.","DOI":"10.1371\/currents.outbreaks.45deb8e03a438c4d088afb4fafae8747"}],"container-title":["Insects"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4450\/11\/5\/307\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T09:28:50Z","timestamp":1760174930000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4450\/11\/5\/307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,14]]},"references-count":28,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020,5]]}},"alternative-id":["insects11050307"],"URL":"https:\/\/doi.org\/10.3390\/insects11050307","relation":{},"ISSN":["2075-4450"],"issn-type":[{"type":"electronic","value":"2075-4450"}],"subject":[],"published":{"date-parts":[[2020,5,14]]}}}