{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T10:21:34Z","timestamp":1784024494949,"version":"3.55.0"},"reference-count":60,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T00:00:00Z","timestamp":1656460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"American Mosquito Control Association: AMCARF","award":["2021-01"],"award-info":[{"award-number":["2021-01"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Insects"],"abstract":"<jats:p>Arthropod control mechanisms are a vital part of public health measures around the world as many insect species serve as vectors for devastating human diseases. Aedes aegypti (Linnaeus, 1762) is a widely distributed, medically important mosquito species that transmits viruses such as yellow fever, Dengue, and Zika. Many traditional control mechanisms have become less effective due to insecticide resistance or exhibit unwanted off-target effects, and, consequently, there is a need for novel solutions. The use of attractive toxic sugar baits (ATSBs) has increased in recent years, though the toxic elements are often harmful to humans and other vertebrates. Therefore, we are investigating propylene glycol, a substance that is generally regarded as safe (GRAS) for human consumption. Using a series of feeding assays, we found that propylene glycol is highly toxic to Ae. aegypti adults and a single day of exposure significantly reduces the survivorship of test populations compared with controls. The effects are more pronounced in males, drastically reducing their survivorship after one day of consumption. Additionally, the consumption of propylene glycol reduced the survivorship of two prominent disease vectors: Aedes albopictus (Skuse, 1894) and Culex pipiens (Linnaeus, 1758). These findings indicate that propylene glycol could be used as a safe and effective alternative to pesticides in an ATSB system.<\/jats:p>","DOI":"10.3390\/insects13070595","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T22:43:28Z","timestamp":1656542608000},"page":"595","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Survivorship-Reducing Effect of Propylene Glycol on Vector Mosquito Populations and Its Potential Use in Attractive Toxic Sugar Baits"],"prefix":"10.3390","volume":"13","author":[{"given":"Heidi","family":"Pullmann Lindsley","sequence":"first","affiliation":[{"name":"Department of Biology, Baylor University, Waco, TX 76798, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry B.","family":"Lyons","sequence":"additional","affiliation":[{"name":"Department of Biology, Baylor University, Waco, TX 76798, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Leon-Nore\u00f1a","sequence":"additional","affiliation":[{"name":"Department of Biology, Baylor University, Waco, TX 76798, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald Jason","family":"Pitts","sequence":"additional","affiliation":[{"name":"Department of Biology, Baylor University, Waco, TX 76798, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.4081\/gh.2014.29","article-title":"Climate change and the potential global distribution of Aedes aegypti: Spatial modelling using geographical information system and CLIMEX","volume":"8","author":"Khormi","year":"2014","journal-title":"Geospat. 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