{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:46:20Z","timestamp":1790747180785,"version":"4.1.0"},"reference-count":77,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T00:00:00Z","timestamp":1666742400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The Turkish Ministry of Agriculture and Forestry, General Directorate of Agricultural Research and Policies (TAGEM)","award":["TAGEM\/HAYS\u00dcD\/B\/20\/A4\/P5\/1890"],"award-info":[{"award-number":["TAGEM\/HAYS\u00dcD\/B\/20\/A4\/P5\/1890"]}]},{"name":"The Turkish Ministry of Agriculture and Forestry, General Directorate of Agricultural Research and Policies (TAGEM)","award":["(PFE)-14\/2022\u20132024"],"award-info":[{"award-number":["(PFE)-14\/2022\u20132024"]}]},{"name":"Romanian Ministry of Research and Innovation","award":["TAGEM\/HAYS\u00dcD\/B\/20\/A4\/P5\/1890"],"award-info":[{"award-number":["TAGEM\/HAYS\u00dcD\/B\/20\/A4\/P5\/1890"]}]},{"name":"Romanian Ministry of Research and Innovation","award":["(PFE)-14\/2022\u20132024"],"award-info":[{"award-number":["(PFE)-14\/2022\u20132024"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Insects"],"abstract":"<jats:p>Honey bee colonies are often subjected to diseases, nutrition quality, temperature and other stresses depending on environmental and climatic conditions. As a result of malnutrition, the level of Vg protein decreases, leading to overwintering losses. The Vg values must be high for a successful wintering, especially before wintering. If good nutrition is not reached, the long winter period may cause an increase in colony losses. Supplementary feeding is essential for colony sustainability when floral resources are insufficient, as in recent years with the emerging climate changes. Furthermore, quality food sources or nutrients are significant for maintaining honey bee health and longevity. This study examined the changes in HSP 70 and Vg proteins in 6 groups of 48 colonies fed with five different nutrients. The fatty acids that are present in the highest amount in Cistus creticus (Pink rock-rose), Papaver somniferum (Opium poppy) and mixed pollen samples were linoleic, palmitic and cis-9-oleic acids. The highest values in proline, lysine and glutamic acid were determined in C. creticus pollen. Regarding the P. somniferum pollen, the highest values were observed in lysine, proline, glutamic and aspartic acids. The highest values in lysine, proline, leucine and aspartic acid were noticed in mixed pollen. The effect of different feeding on Vg protein in nurse and forager bee samples was higher in the mixed pollen group in the fall period. In nurse bees, the mixed pollen group was followed by Cistus creticus pollen &gt; Papaver somniferum pollen &gt; sugar syrup &gt; commercial bee cake &gt; control group, respectively (p &lt; 0.05). In forager bees, the order was mixed pollen, P. somniferum pollen, C. creticus pollen, commercial bee cake, sugar syrup and control. In the early spring period, the Vg levels were high in the mixed pollen group in the nurse bees and the commercial bee cake group in the forager bees. In the fall period, the HSP 70 value of the forager and nurse bees was the lowest in the C. creticus group (p &lt; 0.05). In early spring, the active period of flora, a statistical difference was found between the treatment groups.<\/jats:p>","DOI":"10.3390\/insects13110985","type":"journal-article","created":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T11:53:51Z","timestamp":1666785231000},"page":"985","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Changes in Vitellogenin (Vg) and Stress Protein (HSP 70) in Honey Bee (Apis mellifera anatoliaca) Groups under Different Diets Linked with Physico-Chemical, Antioxidant and Fatty and Amino Acid Profiles"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8287-6617","authenticated-orcid":false,"given":"Aybike","family":"Sario\u011flu-Bozkurt","sequence":"first","affiliation":[{"name":"Department of Biochemistry, School of Veterinary Medicine, Bursa Uludag University, Nil\u00fcfer, 16059 Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1398-4390","authenticated-orcid":false,"given":"Erkan","family":"Topal","sequence":"additional","affiliation":[{"name":"Izmir Food Control Laboratory Directorate, Bornova, 35100 Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazmiye","family":"G\u00fcne\u015f","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, School of Veterinary Medicine, Bursa Uludag University, Nil\u00fcfer, 16059 Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Engin","family":"\u00dc\u00e7e\u015f","sequence":"additional","affiliation":[{"name":"Apiculture Research Center, Aegean Agricultural Research Institute, 35660 Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3313-2416","authenticated-orcid":false,"given":"Mihaiela","family":"Cornea-Cipcigan","sequence":"additional","affiliation":[{"name":"Faculty of Horticulture and Business in Rural Development, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania"},{"name":"Advanced Horticultural Research Institute of Transylvania, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6796-9065","authenticated-orcid":false,"given":"\u0130lknur","family":"Co\u015fkun","sequence":"additional","affiliation":[{"name":"Alt\u0131parmak G\u0131da Sanayi ve Ticaret A.\u015e., 34782 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2742-5143","authenticated-orcid":false,"given":"Lucian","family":"Cuibus","sequence":"additional","affiliation":[{"name":"Department of Food Science, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9246-1677","authenticated-orcid":false,"given":"Rodica","family":"M\u0103rg\u0103oan","sequence":"additional","affiliation":[{"name":"Faculty of Horticulture and Business in Rural Development, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania"},{"name":"Advanced Horticultural Research Institute of Transylvania, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.cois.2018.02.006","article-title":"Feedbacks between nutrition and disease in honey bee health","volume":"26","author":"Dolezal","year":"2018","journal-title":"Curr. 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