{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:58:15Z","timestamp":1769511495857,"version":"3.49.0"},"reference-count":60,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T00:00:00Z","timestamp":1686009600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Maranh\u00e3o State Foundation for Research and Scientific and Technological Development (FAPEMA)","award":["00772\/15"],"award-info":[{"award-number":["00772\/15"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Insects"],"abstract":"<jats:p>Aedes aegypti is the principal vector of the arboviruses\u2014yellow fever, dengue virus, chikungunya, and zika virus. Given the epidemiological importance of this mosquito, its capacity to adapt to different habitats, and its resistance to many types of control measures, systematic research into the genetic variability of the populations of this mosquito is one of the most important steps toward a better understanding of its population structure and vector competence. In this context, the present study verified the presence of distinct genetic lineages of Ae. aegypti in areas with high infestation rates, based on the analysis of microsatellite markers. The samples were collected in nine municipalities with high building infestation rates in the Mid-North region of Brazil. Six microsatellite loci were genotyped in the 138 samples, producing a total of 32 alleles, varying from one to nine alleles per locus in each of the different populations. The AMOVA revealed greater within-population genetic differentiation with high fixation rates. The general analysis of population structure, based on a Bayesian approach, revealed K = 2, with two Ae. aegypti lineages that were highly differentiated genetically. These data on the connectivity of the populations and the genetic isolation of the lineages provide important insights for the development of innovative strategies for the control of the populations of this important disease vector.<\/jats:p>","DOI":"10.3390\/insects14060530","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T02:02:15Z","timestamp":1686103335000},"page":"530","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Genetic Differentiation of Aedes aegypti (Diptera: Culicidae) in Areas with High Rates of Infestation in Mid-North Region of Brazil"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0789-7247","authenticated-orcid":false,"given":"Luzianny Farias","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Graduate Program in Biodiversity, Environment and Health, Laboratory of Genetics and Molecular Biology, Universidade Estadual do Maranh\u00e3o\u2014UEMA, Caxias 65604-380, MA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8251-9073","authenticated-orcid":false,"given":"Andrelina Alves de","family":"Sousa","sequence":"additional","affiliation":[{"name":"Graduate Program in Genetics and Molecular Biology, Laboratory of Genetics and Molecular Biology, Universidade Federal do Par\u00e1\u2014UFPA, Bel\u00e9m 66075-110, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9964-6431","authenticated-orcid":false,"given":"Walter Pinheiro","family":"Mendes J\u00fanior","sequence":"additional","affiliation":[{"name":"Graduate Program in Biodiversity, Environment and Health, Laboratory of Genetics and Molecular Biology, Universidade Estadual do Maranh\u00e3o\u2014UEMA, Caxias 65604-380, MA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Caroline","family":"Cardoso e Silva","sequence":"additional","affiliation":[{"name":"Graduate Program in Biodiversity, Environment and Health, Laboratory of Genetics and Molecular Biology, Universidade Estadual do Maranh\u00e3o\u2014UEMA, Caxias 65604-380, MA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Histelle Sousa do","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Graduate Program Network Biodiversity and Biotechnology of Legal Amazon, Biological Scienses Institute, Bel\u00e9m 66075-110, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Claudene","family":"Barros","sequence":"additional","affiliation":[{"name":"Graduate Program in Biodiversity, Environment and Health, Laboratory of Genetics and Molecular Biology, Universidade Estadual do Maranh\u00e3o\u2014UEMA, Caxias 65604-380, MA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iracilda","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Graduate Program in Genetics and Molecular Biology, Laboratory of Genetics and Molecular Biology, Universidade Federal do Par\u00e1\u2014UFPA, Bel\u00e9m 66075-110, PA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elmary da Costa","family":"Fraga","sequence":"additional","affiliation":[{"name":"Graduate Program in Biodiversity, Environment and Health, Laboratory of Genetics and Molecular Biology, Universidade Estadual do Maranh\u00e3o\u2014UEMA, Caxias 65604-380, MA, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Consoli, R.A.G.B., and Oliveira, R.L. 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