{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:09:59Z","timestamp":1788862199904,"version":"build-2803163510"},"reference-count":129,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Insects"],"abstract":"<jats:p>Poecilocerus pictus and Danaus chrysippus are two common herbivorous insects that share the same host plant, Calotropis gigantea, yet they exhibit distinct feeding preferences and food utilization patterns across leaf ages. D. chrysippus larvae performed better on young leaves, which contain higher water content and suitable nutrients; before feeding, they cut leaf surfaces and inflorescence bases to interrupt latex flow and access floral sugars. P. pictus thrived on mature leaves, which offer a more balanced nutrient composition and moisture level; nymphs made serial cuts on the lower leaf surface to block latex, while adults typically fed from leaf tips. Both species performed poorly on senescent leaves, which are tough, nutrient-poor, and show altered glycoside profiles. Amino acids such as asparagine, proline, glutamine, glutamic acid, valine, alanine, and phenylalanine were more abundant in young leaves, likely explaining the strong preference of D. chrysippus, whereas mature leaves had an amino acid profile better suited to P. pictus. Gas chromatography\u2013mass spectrometry (GC-MS) analysis revealed distinct phytochemical compositions among young, mature, and senescent leaves, as well as inflorescences. These chemical differences, particularly in water, nitrogen, and key metabolites, strongly influence the feeding behavior and growth of both the hemimetabolous grasshopper and the holometabolous butterfly.<\/jats:p>","DOI":"10.3390\/insects17090939","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:02:24Z","timestamp":1788858144000},"page":"939","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Host Plant Biochemical Influence on the Foraging and Food Utilization of Poecilocerus pictus and Danaus chrysippus on Calotropis gigantea: A Behavioral Ecology Approach"],"prefix":"10.3390","volume":"17","author":[{"given":"Yewei","family":"Jia","sequence":"first","affiliation":[{"name":"Department of Entomology, Nanjing Agricultural University (NAU), Nanjing 210095, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6488-5432","authenticated-orcid":false,"given":"Murugan","family":"Vasanthakumaran","sequence":"additional","affiliation":[{"name":"Institute of Marine Biology, National Taiwan Ocean University, Keelung 202301, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7837-6361","authenticated-orcid":false,"given":"Rajapandian","family":"Rajaganesh","sequence":"additional","affiliation":[{"name":"Department of Zoology, Bharathiar University, Coimbatore 641046, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Kadarkarai","family":"Murugan","sequence":"additional","affiliation":[{"name":"Department of Zoology, Bharathiar University, Coimbatore 641046, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0770-8090","authenticated-orcid":false,"given":"Fajun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Entomology, Nanjing Agricultural University (NAU), Nanjing 210095, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e2024463118","DOI":"10.1073\/pnas.2024463118","article-title":"Cardenolides, toxicity, and the costs of sequestration in the coevolutionary interaction between monarchs and milkweeds","volume":"118","author":"Agrawal","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Tooker, J.F., and Giron, D. (2020). The evolution of endophagy in herbivorous insects. Front. Plant Sci., 11.","DOI":"10.3389\/fpls.2020.581816"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1111\/1365-2745.12248","article-title":"Above-ground herbivory by red milkweed beetles facilitates above-and below-ground conspecific insects and reduces fruit production in common milkweed","volume":"102","author":"Erwin","year":"2014","journal-title":"J. Ecol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"677","DOI":"10.18280\/ijdne.160609","article-title":"Toxicity and antifeedant activity of Calotropis gigantea L. leaf extract against Plutella xylostella L. (Lepidoptera: Plutellidae)","volume":"16","author":"Khasanah","year":"2021","journal-title":"Int. J. Des. Nat. Ecodyn."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.4161\/psb.21663","article-title":"Mechanisms of plant defense against insect herbivores","volume":"7","author":"War","year":"2012","journal-title":"Plant Signal. Behav."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.anbehav.2012.06.033","article-title":"Caterpillars use developmental plasticity and diet choice to overcome the early life experience of nutritional imbalance","volume":"84","author":"Lee","year":"2012","journal-title":"Anim. Behav."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"10920","DOI":"10.1073\/pnas.89.22.10920","article-title":"A Host-Inducible Cytochrome P-450 from a Host-Specific Caterpillar: Molecular Cloning and Evolution","volume":"89","author":"Cohen","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2307\/3546331","article-title":"The ecology of plant\/insect interactions: Implications of digestive strategy for feeding by phytophagous insects","volume":"75","author":"Hochuli","year":"1996","journal-title":"Oikos"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Schoonhoven, L.M., van Loon, J.J.A., and Dicke, M. (2005). Insect-Plant Biology, Oxford University Press. [2nd ed.].","DOI":"10.1093\/oso\/9780198525943.001.0001"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0065-2806(08)60230-1","article-title":"The consumption and utilization of food by insects","volume":"5","author":"Waldbauer","year":"1968","journal-title":"Adv. Insect Physiol."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Slansky, F., and Scriber, J.M. (1985). Food Consumption and Utilization. Regulation: Digestion, Nutrition, Excretion, Elsevier.","DOI":"10.1016\/B978-0-08-030805-0.50009-2"},{"key":"ref_12","first-page":"1","article-title":"Regulation of feeding behaviour","volume":"4","author":"Kerkut","year":"1985","journal-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1146\/annurev.es.21.110190.001331","article-title":"Host specialization in phytophagous insects","volume":"21","author":"Jaenike","year":"1990","journal-title":"Annu. Rev. Ecol. Syst."},{"key":"ref_14","unstructured":"Slansky, F., and Rodriguez, J.G. (1987). Nutritional ecology of insects, mites, spiders, and related invertebrates: An overview. Nutritional Ecology of Insects, Mites, Spiders, and Related Invertebrates, John Wiley & Sons."},{"key":"ref_15","first-page":"243","article-title":"Tradeoffs and negative correlations in evolutionary ecology","volume":"150","author":"Agrawal","year":"2010","journal-title":"Evol. Since Darwin First"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Bernays, E.A., and Chapman, R.E. (1994). Host-Plant Selection by Phytophagous Insects, Springer.","DOI":"10.1007\/b102508"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1146\/annurev.en.36.010191.000355","article-title":"Self-selection of optimal diets by insects","volume":"36","author":"Waldbauer","year":"1991","journal-title":"Annu. Rev. Entomol."},{"key":"ref_18","first-page":"135","article-title":"Allelochemical\u2013nutrient interactions in insect nutritional ecology","volume":"Volume 2","author":"Rosenthal","year":"1992","journal-title":"Herbivores: Their Interactions with Secondary Plant Metabolites"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Hedin, P.A. (1983). Impact of variable plant chemistry on insect herbivore population dynamics. Plant Resistance to Insects, American Chemical Society.","DOI":"10.1021\/bk-1983-0208"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1007\/s00442-013-2738-0","article-title":"Plant functional traits reveal the relative contribution of habitat and food preferences to the diet of grasshoppers","volume":"173","author":"Ibanez","year":"2013","journal-title":"Oecologia"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1146\/annurev.ento.46.1.703","article-title":"Neural limitations in phytophagous insects: Implications for diet breadth and evolution of host affiliation","volume":"46","author":"Bernays","year":"2001","journal-title":"Annu. Rev. Entomol."},{"key":"ref_22","unstructured":"Sih, A. (1987). Nutritional ecology and predator\u2013prey dynamics. Nutritional Ecology of Insects, Mites, Spiders, and Related Invertebrates, John Wiley & Sons."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.2307\/1937596","article-title":"Mortality risk vs. food quality trade-offs in patch selection","volume":"71","author":"Nonacs","year":"1990","journal-title":"Ecology"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1461-0248.2009.01309.x","article-title":"Immunological cost of chemical defence and the evolution of herbivore diet breadth","volume":"12","author":"Smilanich","year":"2009","journal-title":"Ecol. Lett."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s00442-018-4068-8","article-title":"Plant and herbivore ontogeny interact to shape the preference, performance and chemical defense of a specialist herbivore","volume":"187","author":"Quintero","year":"2018","journal-title":"Oecologia"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1146\/annurev.en.26.010181.001151","article-title":"The nutritional ecology of immature insects","volume":"26","author":"Scriber","year":"1981","journal-title":"Annu. Rev. Entomol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF00751605","article-title":"Limiting effects of low leaf-water content on the nitrogen utilization efficiency of a cecropia caterpillar","volume":"28","author":"Scriber","year":"1977","journal-title":"Oecologia"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0022-1910(88)90034-0","article-title":"The effects of physiological stress on black cutworm (Agrotis ipsilon) larval growth and food utilization","volume":"34","author":"Schmidt","year":"1988","journal-title":"J. Insect Physiol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"829","DOI":"10.2307\/1936618","article-title":"Growth of herbivorous caterpillars in relation to feeding specialization and to the growth form of their host plants","volume":"60","author":"Scriber","year":"1979","journal-title":"Ecology"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1086\/319302","article-title":"The beneficial acclimation hypothesis versus acclimation of specific traits: Physiological change in water-stressed Manduca sexta caterpillars","volume":"74","author":"Woods","year":"2001","journal-title":"Physiol. Biochem. Zool."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/0022-1910(92)90004-W","article-title":"Feeding and nutritional influence on growth and reproduction of Daphnis nerii (Linn.) (Lepidoptera: Sphingidae)","volume":"38","author":"Murugan","year":"1992","journal-title":"J. Insect Physiol."},{"key":"ref_32","first-page":"213","article-title":"Feeding behavior and host selection in larval insects","volume":"Volume 4","author":"Kerkut","year":"1985","journal-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1111\/j.1570-7458.1978.tb02833.x","article-title":"Metabolic cost of changes in diet and neutralization of allelochemics","volume":"24","author":"Schoonhoven","year":"1978","journal-title":"Entomol. Exp. Appl."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Kaplan, I., McArt, S.H., and Thaler, J.S. (2014). Plant defenses and predation risk differentially shape patterns of consumption, growth, and digestive efficiency in a guild of leaf-chewing insects. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0093714"},{"key":"ref_35","unstructured":"Bernays, E.A., and Barbehenn, R. (1987). Nutritional ecology of grasshoppers and locusts. Nutritional Ecology of Insects, Mites, Spiders, and Related Invertebrates, John Wiley & Sons."},{"key":"ref_36","unstructured":"Mattson, W.J., and Scriber, J.M. (1987). Nutritional ecology of insect herbivores associated with woody plants. Nutritional Ecology of Insects, Mites, Spiders, and Related Invertebrates, John Wiley & Sons."},{"key":"ref_37","unstructured":"Tabashnik, B.E., and Slansky, F. (1987). Nutritional ecology of lepidoptera associated with herbaceous crops. Nutritional Ecology of Insects, Mites, Spiders, and Related Invertebrates, John Wiley & Sons."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1111\/brv.12709","article-title":"Eco-genetics of desiccation resistance in Drosophila","volume":"96","author":"Wang","year":"2021","journal-title":"Biol. Rev."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1570-7458.1973.tb00282.x","article-title":"The regulation of feeding in Locusta migratoria: Internal inhibitory mechanisms","volume":"16","author":"Bernays","year":"1973","journal-title":"Entomol. Exp. Appl."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/BF03186269","article-title":"Physico-chemical factors in the acridid feeding behaviour (Orthoptera: Acrididae)","volume":"94","author":"Muralirangan","year":"1985","journal-title":"Proc. Anim. Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BF00344568","article-title":"Insect herbivory on C3 and C4 grasses","volume":"36","author":"Boutton","year":"1978","journal-title":"Oecologia"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Behmer, S.T., and Joern, A. (2012). Insect herbivore outbreaks viewed through a physiological framework: Insights from Orthoptera. Insect Outbreaks Revisit., 1\u201329.","DOI":"10.1002\/9781118295205.ch1"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"836","DOI":"10.2307\/1938057","article-title":"Plant quality and grasshopper feeding: Effects of sunflower condition on preference and performance in Melanoplus differentialis","volume":"65","author":"Lewis","year":"1984","journal-title":"Ecology"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1365-2311.2008.01004.x","article-title":"Host-plant quality alters grass\/forb consumption by a mixed-feeding insect herbivore, Melanoplus bivittatus (Orthoptera: Acrididae)","volume":"33","author":"Jonas","year":"2008","journal-title":"Ecol. Entomol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1570-7458.1984.tb03440.x","article-title":"Volumetric feedback and the control of meal size in Schistocerca gregaria","volume":"36","author":"Roessingh","year":"1984","journal-title":"Entomol. Exp. Appl."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0022-1910(88)90193-X","article-title":"The cause of reduced growth of Manduca sexta larvae on a low-water diet: Increased metabolic processing costs or nutrient limitation?","volume":"34","author":"Martin","year":"1988","journal-title":"J. Insect Physiol."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Bell, W.J., and Card\u00e9, R.T. (1984). Host-plant suitability. Chemical Ecology of Insects, Chapman & Hall.","DOI":"10.1007\/978-1-4899-3368-3"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1098\/rspb.1975.0076","article-title":"Cardenolide storage in Danaus chrysippus (L.) with additional notes on D. plexippus (L.)","volume":"190","author":"Rothschild","year":"1975","journal-title":"Proc. R. Soc. Lond. B"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1146\/annurev.es.11.110180.001003","article-title":"Herbivory in relation to plant nitrogen content","volume":"11","author":"Mattson","year":"1980","journal-title":"Annu. Rev. Ecol. Syst."},{"key":"ref_50","unstructured":"Rosenthal, G.A., and Janzen, D.H. (1979). Tannins and lignins. Herbivores: Their Interactions with Secondary Plant Metabolites, Academic Press."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0065-2806(08)60152-6","article-title":"Control of food intake","volume":"16","author":"Bernays","year":"1982","journal-title":"Adv. Insect Physiol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1016\/S0031-9422(00)88169-8","article-title":"Inhibitory effect of oak leaf tannins on the hydrolysis of proteins by trypsin","volume":"8","author":"Feeny","year":"1969","journal-title":"Phytochemistry"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/BF00379632","article-title":"Surfactants in the gut fluid of herbivorous insects: Their role in preventing the precipitation of proteins by tannins","volume":"61","author":"Martin","year":"1984","journal-title":"Oecologia"},{"key":"ref_54","doi-asserted-by":"crossref","unstructured":"Chamani, M., Dadpour, M., Dehghanian, Z., Panahirad, S., Chenari Bouket, A., Oszako, T., and Kumar, S. (2025). From digestion to detoxification: Exploring plant metabolite impacts on insect enzyme systems for enhanced pest control. Insects, 16.","DOI":"10.3390\/insects16040392"},{"key":"ref_55","first-page":"422","article-title":"The geometric analysis of nutrient\u2013allelochemical interactions: A case study using locusts","volume":"82","author":"Simpson","year":"2001","journal-title":"Ecology"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1365-2656.2008.01472.x","article-title":"Physical defences wear you down: Progressive and irreversible impacts of silica on insect herbivores","volume":"78","author":"Massey","year":"2009","journal-title":"J. Anim. Ecol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00442-011-1904-5","article-title":"Rapid top\u2013down regulation of plant C:N:P stoichiometry by grasshoppers in an Inner Mongolia grassland ecosystem","volume":"166","author":"Zhang","year":"2011","journal-title":"Oecologia"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s11101-016-9479-8","article-title":"Phytochemical diversity and synergistic effects on herbivores","volume":"15","author":"Richards","year":"2016","journal-title":"Phytochem. Rev."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2307\/3494145","article-title":"Insect nutrition: An adaptationist\u2019s perspective","volume":"65","author":"Slansky","year":"1982","journal-title":"Fla. Entomol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/2937304","article-title":"Host plant selection by Battus philenor butterflies: The roles of predation, nutrition, and plant chemistry","volume":"51","author":"Rausher","year":"1981","journal-title":"Ecol. Monogr."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1146\/annurev.es.07.110176.001005","article-title":"The chemical defenses of plants to pathogens and herbivores","volume":"7","author":"Levin","year":"1976","journal-title":"Annu. Rev. Ecol. Syst."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1126\/science.216.4542.201","article-title":"Plant phenols utilized as nutrients by a phytophagous insect","volume":"216","author":"Bernays","year":"1982","journal-title":"Science"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Neville, A.C. (1975). Biology of the Arthropod Cuticle, Springer.","DOI":"10.1007\/978-3-642-80910-1"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1570-7458.1978.tb02808.x","article-title":"Phenols as indispensible components of the synthetic diet of the silkworm, Bombyx mori","volume":"24","author":"Kato","year":"1978","journal-title":"Entomol. Exp. Appl."},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Singh, S., Kaur, I., and Kariyat, R. (2021). The multifunctional roles of polyphenols in plant-herbivore interactions. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms22031442"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/j.1570-7458.1982.tb03162.x","article-title":"Toxicity of tomato phenolics to the fruitworm, Heliothis zea","volume":"31","author":"Isman","year":"1982","journal-title":"Entomol. Exp. Appl."},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"El-Wakeil, N., Gaafar, N., and Al-Kahtani, S. (2026). Efficiency of Plant Metabolic Products on Insect Pests and Their Parasitoids. Microbiomes and Plant Secondary Metabolites for Insect Pest Management, Springer Nature Switzerland.","DOI":"10.1007\/978-3-032-24330-0_9"},{"key":"ref_68","first-page":"211","article-title":"Quantitative requirement of nutrients for growth of the silkworm, Bombyx mori L","volume":"12","author":"Horie","year":"1978","journal-title":"JARQ"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0022-1910(83)90143-9","article-title":"Effect of various kinds of dietary protein and supplementation with limiting amino acids on growth, haemolymph components and uric acid excretion in the silkworm, Bombyx mori","volume":"29","author":"Horie","year":"1983","journal-title":"J. Insect Physiol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.4039\/Ent1021179-9","article-title":"A quantitative study of food consumption and growth in Pseudaletia unipuncta","volume":"102","author":"Mukerji","year":"1970","journal-title":"Can. Entomol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1093\/aesa\/67.1.66","article-title":"Feeding and nutrition of insects associated with soybeans. 3. Food intake, utilization, and growth in the soybean looper, Pseudoplusia includens","volume":"67","author":"Kogan","year":"1974","journal-title":"Ann. Entomol. Soc. Am."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1080\/10409239991209282","article-title":"Occurrence, biosynthesis, and putative role of ecdysteroids in plants","volume":"34","author":"Adler","year":"1999","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1365-2311.1985.tb00536.x","article-title":"Effects of leaf toughness on mandibular wear and fecundity of Plagiodera versicolora","volume":"10","author":"Raupp","year":"1985","journal-title":"Ecol. Entomol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"73","DOI":"10.5091\/plecevo.2016.1093","article-title":"Herbivory causes increases in leaf spinescence and fluctuating asymmetry as a mechanism of delayed induced resistance in a tropical savanna tree","volume":"149","year":"2016","journal-title":"Plant Ecol. Evol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"565","DOI":"10.2307\/1934037","article-title":"Seasonal changes in oak leaf tannins and nutrients as a cause of spring feeding by winter moth caterpillars","volume":"51","author":"Feeny","year":"1970","journal-title":"Ecology"},{"key":"ref_76","first-page":"1","article-title":"Plant apparency and chemical defense","volume":"Volume 10","author":"Feeny","year":"1976","journal-title":"Biochemical Interaction Between Plants and Insects"},{"key":"ref_77","unstructured":"Lindroth, R.L. (2017). Differential toxicity of plant allelochemicals to insects: Roles of enzymatic detoxication systems. Insect-Plant Interactions 1990, CRC Press."},{"key":"ref_78","first-page":"279","article-title":"Biochemistry of digestion","volume":"Volume 4","author":"Kerkut","year":"1985","journal-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"3206","DOI":"10.1139\/z82-406","article-title":"Digestive proteinases of Sitophilus weevils (Coleoptera: Curculionidae) and their response to inhibitors from wheat and corn flour","volume":"60","author":"Baker","year":"1982","journal-title":"Can. J. Zool."},{"key":"ref_80","first-page":"20","article-title":"Ecdysteroids, juvenile hormone and vitellogenesis in the cockroach Leucophaea maderae","volume":"2","author":"Engelmann","year":"2002","journal-title":"J. Insect Sci."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1146\/annurev.en.18.010173.002121","article-title":"Insect nutrition: Current developments and metabolic implications","volume":"18","author":"Dadd","year":"1973","journal-title":"Annu. Rev. Entomol."},{"key":"ref_82","unstructured":"Townsend, C.R., and Calow, P. (1981). Strategies of digestion and defecation. Physiological Ecology: An Evolutionary Approach to Resource Use, Blackwell Scientific Publications."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0022-1910(86)90108-3","article-title":"The effect of dietary protein on the growth and digestive physiology of larval Spodoptera exigua and Helicoverpa zea","volume":"32","author":"Broadway","year":"1986","journal-title":"J. Insect Physiol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0022-1910(86)90097-1","article-title":"Plant proteinase inhibitors: Mechanism of action and effect on the growth and digestive physiology of larval Heliothis zea and Spodoptera exigua","volume":"32","author":"Broadway","year":"1986","journal-title":"J. Insect Physiol."},{"key":"ref_85","first-page":"165","article-title":"Coordination of digestion and feeding behavior","volume":"Volume 4","author":"Kerkut","year":"1985","journal-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1093\/genetics\/111.3.655","article-title":"Limits of adaptation: The evolution of selective neutrality","volume":"111","author":"Hartl","year":"1985","journal-title":"Genetics"},{"key":"ref_87","unstructured":"Beaumont, S. (1988). Metabolic Coordination and Enzyme Dynamics in Insect Herbivores, Academic Press."},{"key":"ref_88","first-page":"313","article-title":"Insect nutrition: An historical and modern perspective","volume":"Volume 4","author":"Kerkut","year":"1985","journal-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology"},{"key":"ref_89","first-page":"391","article-title":"Nutrition: Carbohydrates","volume":"Volume 4","author":"Kerkut","year":"1985","journal-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology"},{"key":"ref_90","first-page":"133","article-title":"Nutritional diseases in insects","volume":"Volume 1","author":"Steinhaus","year":"1963","journal-title":"Insect Pathology: An Advanced Treatise"},{"key":"ref_91","unstructured":"Kohlmann-Cuesta, B. (1988). The Ecological Genetics of a Narrow Hybrid Zone: The Case of Caledia captiva (Fabricius) (Orthoptera: Acrididae). [Ph.D. Thesis, The Australian National University]."},{"key":"ref_92","first-page":"77","article-title":"Lipid metabolism","volume":"Volume 10","author":"Kerkut","year":"1985","journal-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology"},{"key":"ref_93","first-page":"677","article-title":"Insect flight metabolism","volume":"15","author":"Beenakkers","year":"1985","journal-title":"Insect Biochem."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0065-2806(08)60208-8","article-title":"Lipid metabolism and function in insects","volume":"4","author":"Gilbert","year":"1967","journal-title":"Adv. Insect Physiol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"17174","DOI":"10.1016\/S0021-9258(19)76015-3","article-title":"Lipoprotein biosynthesis in the larvae of the tobacco hornworm, Manduca sexta","volume":"261","author":"Prasad","year":"1986","journal-title":"J. Biol. Chem."},{"key":"ref_96","first-page":"241","article-title":"Absorption and transport of lipids","volume":"Volume 10","author":"Kerkut","year":"1985","journal-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/0022-1910(90)90071-M","article-title":"Plant leaf lipids as fatty acid sources in two species of Lepidoptera","volume":"36","author":"Turunen","year":"1990","journal-title":"J. Insect Physiol."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/0022-1910(89)90125-X","article-title":"Relationship between dietary lipids, midgut lipids, and lipid absorption in eight species of Lepidoptera reared on artificial and natural diets","volume":"35","author":"Turunen","year":"1989","journal-title":"J. Insect Physiol."},{"key":"ref_99","unstructured":"Huffaker, C.B., and Rabb, R.L. (1984). Nutritional ecology of phytophagous insects. Ecological Entomology, John Wiley & Sons."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1126\/science.206.4414.83","article-title":"Male contribution to egg production in butterflies: Evidence for transfer of nutrients at mating","volume":"206","author":"Boggs","year":"1979","journal-title":"Science"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/BF00344970","article-title":"Population structure of pierid butterflies IV. Genetic and physiological investment in offspring by male Colias","volume":"50","author":"Boggs","year":"1981","journal-title":"Oecologia"},{"key":"ref_102","first-page":"399","article-title":"Contribution of Larval Nutrition to Adult Reproduction in Drosophila melanogaster","volume":"216","author":"Aguila","year":"2012","journal-title":"J. Exp. Biol."},{"key":"ref_103","unstructured":"Engelmann, F. (1970). The Physiology of Insect Reproduction, Pergamon Press."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0003-3472(05)81017-6","article-title":"Sexual cannibalism in the praying mantid, Mantis religiosa: A field study","volume":"43","author":"Lawrence","year":"1992","journal-title":"Anim. Behav."},{"key":"ref_105","doi-asserted-by":"crossref","unstructured":"Eisenberg, R.M., Hurd, L.E., and Bartley, J.A. (1981). Ecological consequences of food limitation for adult mantids (Tenodera ardifolia sinensis Saussure). Am. Midl. Nat., 209\u2013218.","DOI":"10.2307\/2425157"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1093\/ee\/24.2.348","article-title":"Time, temperature, and food as determinants of population persistence in the temperate mantid Tenodera sinensis (Mantodea: Mantidae)","volume":"24","author":"Hurd","year":"1995","journal-title":"Environ. Entomol."},{"key":"ref_107","first-page":"1","article-title":"Consequences of dietary amino acid imbalance for growth and gas exchange in black soldier fly (Hermetia illucens) larvae","volume":"1","author":"Jensen","year":"2026","journal-title":"J. Insects Food Feed"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"3236","DOI":"10.1242\/jeb.008060","article-title":"The interactive effects of protein quality and macronutrient imbalance on nutrient balancing in an insect herbivore","volume":"210","author":"Lee","year":"2007","journal-title":"J. Exp. Biol."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1570-7458.1969.tb02560.x","article-title":"Effects of different proportions of nutrients on insects","volume":"12","author":"House","year":"1969","journal-title":"Entomol. Exp. Appl."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1111\/j.1570-7458.1969.tb02552.x","article-title":"Chemosensory basis of host-plant selection in the silkworm","volume":"12","author":"Ishikawa","year":"1969","journal-title":"Entomol. Exp. Appl."},{"key":"ref_111","first-page":"299","article-title":"Host selection behaviour of aphid parasitoids (Aphidiidae: Hymenoptera)","volume":"2","author":"Rehman","year":"2010","journal-title":"J. Plant Breed. Crop Sci."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0022-1910(87)90077-1","article-title":"Nutrient self-selection by the omnivorous cockroach Supella longipalpa","volume":"33","author":"Cohen","year":"1987","journal-title":"J. Insect Physiol."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1590\/S1519-566X2004000500003","article-title":"Selection of oviposition sites by wild Anastrepha obliqua (Macquart) (Diptera: Tephritidae) based on the nutritional composition","volume":"33","author":"Zucoloto","year":"2004","journal-title":"Neotrop. Entomol."},{"key":"ref_114","first-page":"631","article-title":"Influence of previous experience on the preference, food utilization and performance of Ascia monuste orseis wild larvae (Godart) (Lepidoptera: Pieridae) for three different hosts","volume":"40","author":"Santana","year":"2011","journal-title":"Neotrop. Entomol."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1570-7458.1988.tb01119.x","article-title":"Dietary self-selection for vitamins and lipid by larvae of the corn earworm, Heliothis zea","volume":"46","author":"Schiff","year":"1988","journal-title":"Entomol. Exp. Appl."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s10886-018-1040-3","article-title":"Toxicity of milkweed leaves and latex: Chromatographic quantification versus biological activity of cardenolides in 16 Asclepias species","volume":"45","author":"Petschenka","year":"2019","journal-title":"J. Chem. Ecol."},{"key":"ref_117","unstructured":"Dussourd, D.E. (1986). Vein-Cutting Behavior of Insect Herbivores on Latex-Bearing Plants. [Ph.D. Thesis, Cornell University]."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"20232721","DOI":"10.1098\/rspb.2023.2721","article-title":"Late-instar monarch caterpillars sabotage milkweed to acquire toxins, not to disarm plant defence","volume":"291","author":"Betz","year":"2024","journal-title":"Proc. R. Soc. B"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1126\/science.3616620","article-title":"Vein-cutting behavior: Insect counterploy to the latex defense of plants","volume":"237","author":"Dussourd","year":"1987","journal-title":"Science"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s00049-005-0291-y","article-title":"Glues or poisons: Which triggers vein cutting by monarch caterpillars?","volume":"15","author":"Helmus","year":"2005","journal-title":"Chemoecology"},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1046\/j.1440-6055.2000.00191.x","article-title":"Foraging and vein-cutting behaviour of Euploea core corinna (W.S. Macleay) (Lepidoptera: Nymphalidae) caterpillars feeding on latex-bearing leaves","volume":"39","author":"Clarke","year":"2000","journal-title":"Aust. J. Entomol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1365-2311.1990.tb00804.x","article-title":"Oviposition by Danaus plexippus in relation to cardenolide content of three Asclepias species in the southeastern USA","volume":"15","author":"Zalucki","year":"1990","journal-title":"Ecol. Entomol."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1365-2311.1990.tb00799.x","article-title":"Cardiac glycosides and oviposition site selection in Danaus plexippus","volume":"15","author":"Oyeyele","year":"1990","journal-title":"Ecol. Entomol."},{"key":"ref_124","first-page":"1151","article-title":"Cardenolide sequestration by the dogbane tiger moth (Saucrobotys futilis)","volume":"8","author":"Cohen","year":"1982","journal-title":"J. Chem. Ecol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF01245886","article-title":"Survival of first instar larvae of Danaus plexippus (Lepidoptera: Danainae) in relation to cardiac glycoside and latex content of Asclepias humistrata (Asclepiadaceae)","volume":"3","author":"Zalucki","year":"1992","journal-title":"Chemoecology"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1126\/science.198.4320.942","article-title":"Plant crops as a source of rubber and hydrocarbon-like materials","volume":"198","author":"Nielsen","year":"1977","journal-title":"Science"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1016\/0031-9422(82)85202-3","article-title":"Cardenolides in the latex and leaves of seven Asclepias species and Calotropis procera","volume":"21","author":"Seiber","year":"1982","journal-title":"Phytochemistry"},{"key":"ref_128","unstructured":"Nishio, S. (1980). Cardenolide Distribution Within Individual Milkweed Plants and Its Ecological Significance. [Master\u2019s Thesis, University of California]."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1007\/BF00987622","article-title":"Seasonal and intraplant variation of cardenolide content in Asclepias eriocarpa","volume":"7","author":"Nelson","year":"1981","journal-title":"J. Chem. Ecol."}],"container-title":["Insects"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4450\/17\/9\/939\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T09:14:41Z","timestamp":1788858881000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4450\/17\/9\/939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,8]]},"references-count":129,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["insects17090939"],"URL":"https:\/\/doi.org\/10.3390\/insects17090939","relation":{},"ISSN":["2075-4450"],"issn-type":[{"value":"2075-4450","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,8]]}}}