{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:28:37Z","timestamp":1791390517811,"version":"4.3.3"},"reference-count":36,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:00:00Z","timestamp":1686873600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>Optimal fluid therapy during perioperative care as part of enhanced recovery after cardiac surgery (ERACS) should improve the outcome. Our objective was finding out the effects of fluid overload on outcome and mortality within a well-established ERACS program. All consecutive patients undergoing cardiac surgery between January 2020 and December 2021 were enrolled. According to ROC curve analysis, a cut-off of \u22657 kg (group M, n = 1198) and &lt;7 kg (group L, n = 1015) was defined. A moderate correlation was shown between weight gain and fluid balance r = 0.4, and a simple linear regression was significant p &lt; 0.0001, R2 = 0.16. Propensity score matching showed that increased weight gain was associated with a longer hospital length of stay (LOS) (L 8 [3] d vs. M 9 [6] d, p &lt; 0.0001), an increased number of patients who received pRBCs (L 311 (36%) vs. M 429 (50%), p &lt; 0.0001), and a higher incidence of postoperative acute kidney injury (AKI) (L 84 (9.8%) vs. M 165 (19.2%), p &lt; 0.0001). Weight gain can easily represent fluid overload. Fluid overload after cardiac surgery is common and is associated with prolonged hospital LOS and increases the incidence of AKI.<\/jats:p>","DOI":"10.3390\/jcdd10060263","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T08:56:01Z","timestamp":1686905761000},"page":"263","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Postoperative Weight Gain within Enhanced Recovery after Cardiac Surgery"],"prefix":"10.3390","volume":"10","author":[{"given":"Alexandra","family":"Kr\u00fcger","sequence":"first","affiliation":[{"name":"Heart Center Leipzig, University of Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Flo Forner","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Ender","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniruddha","family":"Janai","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youssef","family":"Roufail","sequence":"additional","affiliation":[{"name":"Health Sciences, Faculty of Science, Waterloo Campus, Wilfrid Laurier University, Waterloo, ON N2L 3C5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Otto","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Heart Center Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Meineri","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waseem Z. A.","family":"Zakhary","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Str\u00fcmpellstra\u00dfe 39, 04289 Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.4236\/wjcs.2011.12004","article-title":"Fluid Overload after Coronary Artery Bypass Grafting Surgery Increases the Incidence of Post-Operative Complications","volume":"1","author":"Morin","year":"2011","journal-title":"WJCS"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1001\/jamasurg.2019.1153","article-title":"Guidelines for Perioperative Care in Cardiac Surgery: Enhanced Recovery After Surgery Society Recommendations","volume":"154","author":"Engelman","year":"2019","journal-title":"JAMA Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1097\/CCM.0000000000001479","article-title":"Effect of Perioperative Goal-Directed Hemodynamic Resuscitation Therapy on Outcomes Following Cardiac Surgery: A Randomized Clinical Trial and Systematic Review","volume":"44","author":"Osawa","year":"2016","journal-title":"Crit. 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