{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T16:30:26Z","timestamp":1778862626479,"version":"3.51.4"},"reference-count":14,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T00:00:00Z","timestamp":1719273600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>Background: Stent implantation has become the preferred method of treatment for treating vessel stenosis in congenital heart diseases. The availability of covered stents may decrease complications and have an important role in the management of patients with complex anatomy. Aim: This study aims to evaluate the feasibility and safety of the pre-mounted cobalt\u2013chromium stent-graft-covered ePTFE Aortic BeGraft in a broad spectrum of vascular lesions. Methods: This is a multicenter retrospective results analysis of 107 implanted BeGraft stents between 2016 and 2022 in six different European centers. Results: One hundred and four patients with a mean age of thirteen years (range 1\u201370 years) and with the body weight of 56.5 kg (range 11\u2013115 kg) underwent the BeGraft stent implantation. Stents were implanted in the following conditions: aortic coarctation (74 patients), RVOT dysfunction (12 patients), Fontan circulation (7 patients), and miscellaneous (11 subjects with complex CHD). All the stents were implanted successfully. The median stent diameter was 16 mm (range 7\u201324 mm), and the median length was 39 mm (range 19\u201349 mm). Major complications occurred in five subjects (4.7%). During a median follow-up of fourteen (1\u201370) months, stents\u2019 re-dilatation was performed in five patients. Conclusions: The BeGraft stent can be used safely and effectively in a wide spectrum of congenital heart diseases. Whether these good results will be stable in the longer term still needs to be investigated in a follow-up given its recent introduction into clinical practice, in particular regarding stent fracture or neointimal proliferation.<\/jats:p>","DOI":"10.3390\/jcdd11070192","type":"journal-article","created":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T12:46:56Z","timestamp":1719319616000},"page":"192","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["BeGraft Aortic Stents: A European Multi-Centre Experience Reporting Acute Safety and Efficacy Outcomes for the Treatment of Vessel Stenosis in Congenital Heart Diseases"],"prefix":"10.3390","volume":"11","author":[{"given":"Micol","family":"Rebonato","sequence":"first","affiliation":[{"name":"Department of Pediatric Cardiology, Cardiac Surgery and Heart Lung Transplantation, Bambino Ges\u00f9 Children\u2019s Hospital, IRCCS, 00165 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mara","family":"Pilati","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Cardiac Surgery and Heart Lung Transplantation, Bambino Ges\u00f9 Children\u2019s Hospital, IRCCS, 00165 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie Malekzadeh","family":"Milani","sequence":"additional","affiliation":[{"name":"Centre de R\u00e9f\u00e9rence Malformations Cardiaques Cong\u00e9nitales Complexes\u2014M3C, H\u00f4pital Universitaire Necker Enfants Malades, F-75015 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8722-5805","authenticated-orcid":false,"given":"Damien","family":"Bonnet","sequence":"additional","affiliation":[{"name":"Centre de R\u00e9f\u00e9rence Malformations Cardiaques Cong\u00e9nitales Complexes\u2014M3C, H\u00f4pital Universitaire Necker Enfants Malades, F-75015 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma","family":"Pascall","sequence":"additional","affiliation":[{"name":"Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2006-3426","authenticated-orcid":false,"given":"Matthew","family":"Jones","sequence":"additional","affiliation":[{"name":"Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Betrian","sequence":"additional","affiliation":[{"name":"Hospital Universitari Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Bianco","sequence":"additional","affiliation":[{"name":"Hospital Universitari Vall d\u2019Hebron, 08035 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugues","family":"Lucron","sequence":"additional","affiliation":[{"name":"H\u00f4pital Marie-Lannelongue, F-92350 Le Plessis-Robinson, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8695-0503","authenticated-orcid":false,"given":"Sebastien","family":"Hascoet","sequence":"additional","affiliation":[{"name":"H\u00f4pital Marie-Lannelongue, F-92350 Le Plessis-Robinson, France"},{"name":"Groupe Hospitalier Paris Saint Joseph, F-75014 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2548-7858","authenticated-orcid":false,"given":"Alban-Elouen","family":"Baruteau","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Pediatric Cardiac Surgery, CHU Nantes, Nantes Universit\u00e9, FHU PRECICARE, F-44000 Nantes, France"},{"name":"CIC FEA 1413, INSERM, CHU Nantes, Nantes Universit\u00e9, F-44000 Nantes, France"},{"name":"L\u2019Institut du Thorax, INSERM, CNRS, CHU Nantes, Nantes Universit\u00e9, F-44000 Nantes, France"},{"name":"UMR 1280, PhAN, INRAE, Nantes Universit\u00e9, F-44000 Nantes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Giugno","sequence":"additional","affiliation":[{"name":"IRCCS Policlinico, 20097 San Donato, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1288-0108","authenticated-orcid":false,"given":"Gianfranco","family":"Butera","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Cardiac Surgery and Heart Lung Transplantation, Bambino Ges\u00f9 Children\u2019s Hospital, IRCCS, 00165 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1017\/S1047951121002389","article-title":"Endovascular treatment of aortic coarctation with a novel BeGraft aortic stent in children and young adults: A single-centre experience with short-term follow-up results","volume":"32","author":"Vuran","year":"2022","journal-title":"Cardiol. Young"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.ijcard.2014.04.271","article-title":"Use of covered Cheatham-Platinum stents in congenital heart disease","volume":"175","author":"Vanagt","year":"2014","journal-title":"Int. J. Cardiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1017\/S1047951110001459","article-title":"Large-diameter graft-stent (Advanta V12) implantation in various locations: Early results","volume":"21","author":"Schranz","year":"2011","journal-title":"Cardiol. Young"},{"key":"ref_4","first-page":"441","article-title":"Cheatham-Platinum stent for native and recurrent aortic coarctation in children and adults: Immediate and early follow-up results","volume":"11","author":"Erdem","year":"2011","journal-title":"Anadolu Kardiyol. Derg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1002\/ccd.24594","article-title":"Off-label use of percutaneous pulmonary valved stents in the right ventricular outflow tract: Time to rewrite the label?","volume":"81","author":"Boshoff","year":"2013","journal-title":"Catheter. Cardiovasc. Interv."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1136\/hrt.2004.040071","article-title":"The CP stent\u2013short, long, covered\u2014For the treatment of aortic coarctation, stenosis of pulmonary arteries and caval veins, and Fontan anastomosis in children and adults: An evaluation of 60 stents in 53 patients","volume":"91","author":"Ewert","year":"2005","journal-title":"Heart"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/ccd.20652","article-title":"Covered stents in patients with congenital heart defects","volume":"67","author":"Butera","year":"2006","journal-title":"Catheter. Cardiovasc. Interv."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ijcard.2008.11.085","article-title":"Covered stents in the management of coarctation of the aorta in the adult: Initial results and 1-year angiographic and hemodynamic follow-up","volume":"140","author":"Tanous","year":"2010","journal-title":"Int. J. Cardiol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.jcin.2015.11.038","article-title":"Immediate Outcomes of Covered Stent Placement for Treatment or Prevention of Aortic Wall Injury Associated with Coarctation of the Aorta (COAST II)","volume":"9","author":"Taggart","year":"2016","journal-title":"JACC Cardiovasc. Interv."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1017\/S1047951120003728","article-title":"Initial experience with a novel ePTFE-covered balloon expandable stent in patients with near-atretic or severe aortic coarctation and small femoral arterial access","volume":"31","author":"Pascall","year":"2021","journal-title":"Cardiol. Young"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"E310","DOI":"10.1002\/ccd.28892","article-title":"Feasibility and early outcomes of aortic coarctation treatments with BeGraft Aortic stent","volume":"96","author":"Promphan","year":"2020","journal-title":"Catheter. Cardiovasc. Interv."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1017\/S1047951122003237","article-title":"Early outcomes of the treatment of aortic coarctation with BeGraft aortic stent in children and young adults","volume":"33","author":"Kavurt","year":"2023","journal-title":"Cardiol. Young"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s00246-004-0814-2","article-title":"Use of covered stents in the man-agement of coarctation of the aorta","volume":"26","author":"Pedra","year":"2005","journal-title":"Pediatr. Cardiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1080\/00015385.2020.1838126","article-title":"Covered stent placement for treatment of coarctation of the aorta: Immediate and long-term results","volume":"76","author":"Stassen","year":"2021","journal-title":"Acta Cardiol."}],"container-title":["Journal of Cardiovascular Development and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2308-3425\/11\/7\/192\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:04:18Z","timestamp":1760108658000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2308-3425\/11\/7\/192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,25]]},"references-count":14,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["jcdd11070192"],"URL":"https:\/\/doi.org\/10.3390\/jcdd11070192","relation":{},"ISSN":["2308-3425"],"issn-type":[{"value":"2308-3425","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,25]]}}}