{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:15:06Z","timestamp":1760145306245,"version":"build-2065373602"},"reference-count":14,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014677","name":"University of Medicine, Pharmacy, Science and Technology","doi-asserted-by":"publisher","award":["511\/5\/17.01.2022"],"award-info":[{"award-number":["511\/5\/17.01.2022"]}],"id":[{"id":"10.13039\/501100014677","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCDD"],"abstract":"<jats:p>Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare and potentially life-threatening condition affecting infants that requires immediate corrective surgery to restore blood flow to the myocardium. We present a case of an infant with ALCAPA and severe heart failure. What sets this case apart is the utilization of speckle-tracking echocardiography as a non-invasive method for assessing global and regional myocardial function before and after surgical intervention. Our preoperative analysis revealed compromised contraction in specific areas of the left ventricle (LV), in the regions that were supplied by both the left coronary artery (LCA) and the right coronary artery (RCA). Interestingly, despite an increase in ejection fraction (EF) measured by conventional echocardiography, the postoperative speckle-tracking analysis revealed persistent impairment in the anterior territories supplied by LCA, highlighting the potential of this technique in identifying myocardial abnormalities during postoperative follow-up. In conclusion, speckle-tracking echocardiography may be a valuable tool for identifying subtle myocardial changes in ALCAPA patients with a higher sensitivity in detecting regional left ventricular (LV) dysfunction compared to conventional echocardiography.<\/jats:p>","DOI":"10.3390\/jcdd11070219","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T11:30:55Z","timestamp":1720697455000},"page":"219","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Advanced Echocardiography Assessment in the Management of Alcapa Syndrome: Case Report"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1521-3503","authenticated-orcid":false,"given":"Asmaa Carla","family":"Hag\u0103u","sequence":"first","affiliation":[{"name":"Doctoral School of Medicine and Pharmacy, I.O.S.U.D., George Emil Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u0219, 540136 T\u00e2rgu Mure\u0219, Romania"},{"name":"Clinic of Paediatric Cardiology, Emergency Institute for Cardiovascular Diseases and Transplantation of T\u00e2rgu Mure\u0219, 540139 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hora\u021biu","family":"Suciu","sequence":"additional","affiliation":[{"name":"Department of Surgery IV, Emergency Institute of Cardiovascular Diseases and Transplantation T\u00e2rgu Mure\u0219, 540139 T\u00e2rgu Mure\u0219, Romania"},{"name":"Department of Surgery, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u0219, 540142 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anca Voichi\u021ba","family":"Popoiu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Hospital \u201cLouis Turcanu\u201d, 300732 Timisoara, Romania"},{"name":"Department of Pediatrics, University of Medicine and Pharmacy \u201cVictor Babes\u201d Timisoara, 300732 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iolanda","family":"Muntean","sequence":"additional","affiliation":[{"name":"Clinic of Paediatric Cardiology, Emergency Institute for Cardiovascular Diseases and Transplantation of T\u00e2rgu Mure\u0219, 540139 T\u00e2rgu Mure\u0219, Romania"},{"name":"Department of Pediatrics III, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u0219, 540142 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.echo.2019.12.014","article-title":"Myocardial Function Following Repair of Anomalous Origin of Left Coronary Artery from the Pulmonary Artery in Children","volume":"33","author":"Naqvi","year":"2020","journal-title":"J. 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Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1161\/HYPERTENSIONAHA.119.12956","article-title":"Characterization of Myocardial Microstructure and Function in an Experimental Model of Isolated Subendocardial Damage","volume":"74","author":"Beyhoff","year":"2019","journal-title":"Hypertension"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.echo.2022.11.006","article-title":"Pediatric Normal Values and Z Score Equations for Left and Right Ventricular Strain by Two-Dimensional Speckle-Tracking Echocardiography Derived from a Large Cohort of Healthy Children","volume":"36","author":"Romanowicz","year":"2023","journal-title":"J. Am. Soc. Echocardiogr."}],"container-title":["Journal of Cardiovascular Development and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2308-3425\/11\/7\/219\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:13:07Z","timestamp":1760109187000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2308-3425\/11\/7\/219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,11]]},"references-count":14,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["jcdd11070219"],"URL":"https:\/\/doi.org\/10.3390\/jcdd11070219","relation":{},"ISSN":["2308-3425"],"issn-type":[{"type":"electronic","value":"2308-3425"}],"subject":[],"published":{"date-parts":[[2024,7,11]]}}}